Targeting the Liver with Nucleic Acid Therapeutics for the Treatment of Systemic Diseases of Liver Origin

This article aims to provide the most updated information on targeting the liver with ASO and siRNA drugs. The generated knowledge may stimulate further investigations in this growing field of new therapeutic entities for the treatment of some human systemic diseases, which currently have no or limited options for treatment.PMID:37696583 | DOI:10.1124/pharmrev.123.000815

Source: Pharmacological Reviews - September 11, 2023 Category: Drugs & Pharmacology Authors: Anagha Gogate Jordyn Belcourt Milan Shah Alicia Zongxun Wang Alexis Frankel Holly Kolmel Matthew Chalon Prajith Stephen Aarush Kolli Sherouk M Tawfik Jing Jin Raman Bahal Theodore P Rasmussen Jose E Manautou Xiao-Bo Zhong Source Type: research