Suicidal Behavior in Patients With MDD Associated With Death of Any Cause

Individuals with major depressive disorder (MDD) who exhibit suicidal behavior have 2.6 times the risk of dying from any cause compared with people with MDD who do not, according to astudy published this week inJAMA Psychiatry.“[MDD] is an important risk factor of suicidal behavior, but the added burden of suicidal behavior and MDD on the patient and societal level, including all-cause mortality, is not well studied,” wrote Johan Lundberg, M.D, Ph.D., of the Karolinska Institutet in Stockholm and colleagues. “Also, the contribution of various prognostic factors for suicidal behavior has not been quantified in larger samples.”Lundberg and colleagues used data from the Stockholm MDD Cohort, which includes all patients diagnosed with MDD in any health care setting in the Stockholm region. The data included diagnoses, history of suicidal behaviors, days worked in the past month, and overall health care utilization such as number of outpatient physician visits and inpatient bed days per month. Further, the data included the date of death but not the cause of death.The researchers identified all diagnosed MDD episodes among people aged 18 and older between 2012 and 2017, excluding those individuals with a history of psychosis, bipolar disorder, or dementia. Individuals whose depressive episode included suicidal behavior were matched with up to five individuals who had MDD without suicidal behavior of similar age, sex, year of MDD diagnosis, and sociodemographic status.The s...
Source: Psychiatr News - Category: Psychiatry Tags: anxiety Johan Lundberg Karolinska Institutet major depressive disorder personality disorders substance use suicidal behavior Source Type: research