Cardiac regeneration – Past advancements, current challenges, and future directions
Cardiovascular disease is the leading cause of mortality and morbidity worldwide. Despite improvements in the standard of care for patients with heart diseases, including innovation in pharmacotherapy and surgical interventions, none have yet been proven effective to prevent the progression to heart failure. Cardiac transplantation is the last resort for patients with severe heart failure, but donor shortages remain a roadblock. Cardiac regenerative strategies include cell-based therapeutics, gene therapy, direct reprogramming of non-cardiac cells, acellular biologics, and tissue engineering methods to restore damaged hearts.
Source: Journal of Molecular and Cellular Cardiology - Category: Cytology Authors: Arash Pezhouman, Ngoc B. Nguyen, Maryam Kay, Baishali Kanjilal, Iman Noshadi, Reza Ardehali Source Type: research
More News: Cardiology | Cardiovascular | Cytology | Gene Therapy | Genetics | Heart | Heart Failure | Heart Transplant | Molecular Biology | Transplants