Metformin ameliorates ferroptosis in cardiac ischemia and reperfusion by reducing NOX4 expression via promoting AMPK α

CONCLUSIONS: Met shows effectiveness in relieving ferroptosis in cardiac I/R. In the future, Met may be an effective drug for relieving ferroptosis in cardiac I/R patients clinically.PMID:37288723 | DOI:10.1080/13880209.2023.2212700

Source: Pharmaceutical Biology - June 8, 2023 Category: Drugs & Pharmacology Authors: Zhenhua Wu Yunpeng Bai Yujuan Qi Chao Chang Yan Jiao Yaobang Bai Zhigang Guo Source Type: research