The Duration of an Exposure Response Gradient between Incident Obstructive Airways Disease and Work at the World Trade Center Site: 2001-2011
We examined how lower respiratory symptoms were associated with OAD diagnoses within individuals. Table 3 shows the relationship of physician diagnoses of OAD to prior self-reported OAD symptoms of cough, wheeze, and shortness of breath. Most persons who developed OAD reported symptoms prior to physician diagnosis, and this was true throughout the follow-up period. However, the majority of persons who never received an OAD diagnosis also reported OAD symptoms. Of the 2,286 persons who received an OAD diagnosis during the follow-up period, 1,934 (84.6%) took a medical monitoring questionnaire and completed the question on self-reported lower respiratory symptoms during the first 15 months. Of those, 1,559 reported at least one lower respiratory symptom during the first 15 months, for an overall sensitivity of 80.6%.Table 3. Fraction of persons reporting OAD symptoms on medical monitoring questionnaires by month of OAD diagnosis.
*1,471 persons did not complete a medical monitoring questionnaire during the first 15 months and are excluded from this column.
Month of OAD diagnosis
#/N (%) self-reporting OAD symptoms in first 15 months*
#/N self-reporting OAD symptoms in any prior period
1-15
321/351 (91.5%)
–
16-60
477/585 (81.5%)
477/685 (69.6%)
61-84
288/369 (78.1%)
319/432 (73.8%)
85-120
473/629 (75.2%)
554/745 (74.4%)
Never
4,088/6,373 (64.2%)
4,682/7,492 (62.5%)
Entire cohort
5,647/8,307 (68.0%)
9,778
Persons whose first physician diagnosis of OAD ...
Source: PLOS Currents Disasters - Category: Global & Universal Authors: Charles Hall Source Type: research
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