Glycemic Control and Effects of Canagliflozin in Reducing Albuminuria and eGFR: A Post Hoc Analysis of the CREDENCE Trial

Conclusions The effect of canagliflozin on eGFR slope in patients with type 2 diabetes and CKD was more pronounced in patients with higher baseline HbA1c, due partly to the more rapid decline in kidney function in these individuals.PMID:36999981 | DOI:10.2215/CJN.0000000000000161

Source: Clinical Journal of the American Society of Nephrology : CJASN - March 31, 2023 Category: Urology & Nephrology Authors: Sjoukje van der Hoek Niels Jongs Megumi Oshima Brendon L Neuen Jasper Stevens Vlado Perkovic Adeera Levin Kenneth W Mahaffey Carol Pollock Tom Greene David C Wheeler Meg J Jardine Hiddo J L Heerspink Source Type: research