Prognostic factors for the development and progression of proliferative diabetic retinopathy in people with diabetic retinopathy

CONCLUSIONS: Increased HbA1c is likely to be associated with progression to PDR; therefore, maintaining adequate glucose control throughout life, irrespective of stage of DR severity, may help to prevent progression to PDR and risk of its sight-threatening complications. Renal impairment in people with T1D or T2D, as well as younger age at diagnosis of diabetes mellitus (DM), increased triglyceride levels, and increased retinal venular diameters in people with T1D may also be associated with increased risk of progression to PDR. Given that more advanced DR severity is associated with higher risk of progression to PDR, the earlier the disease is identified, and the above systemic risk factors are controlled, the greater the chance of reducing the risk of PDR and saving sight.PMID:36815723 | DOI:10.1002/14651858.CD013775.pub2
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Source Type: research