Chronic ethanol exposure induces mitochondrial dysfunction and alters gene expression and metabolism in human cardiac spheroids
CONCLUSION: Chronic ethanol treatment of hiPSC-CMs resulted in overall decreased mitochondrial function, increased glycolysis, disrupted fatty acid oxidation, and impaired cardiac structural development.PMID:36799338 | DOI:10.1111/acer.15026
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Hyun Hwang Rui Liu Ronald Eldridge Xin Hu Parvin Forghani Dean P Jones Chunhui Xu Source Type: research
More News: Addiction | Alcoholism | Arrhythmia | Cardiology | Cardiomyopathy | Genetics | Heart | Heart Failure | Stem Cell Therapy | Stem Cells | Toxicology