New strategies in the treatment of diseases caused by Acanthamoeba based on nanoparticles: a systematic review

CONCLUSION: This study showed that chlorhexidine and other plant metabolites loaded with silver and gold nanoparticles increase the anti-Acanthambae activity of these nanoparticles. However, green synthesized nanoparticles based on stabilization by plant gums, loaded with citrus fruits flavonoids hesperidin (HDN) and naringin (NRG), showed the best anti-Acanthambae effect. Nevertheless, further studies should be performed to determine their safety for human use.PMID:36372923 | DOI:10.2174/2772432818666221111155119

Source: Pharmacological Reviews - November 14, 2022 Category: Drugs & Pharmacology Authors: Pegah Shakib Hamed Kalani Muhammad Tahir Aleem Roghiyeh Faridnia Mustafa Zebardast Pour Kobra Moradpour Kourosh Cheraghipour Source Type: research