Role of ATP-binding cassette transporters in efflux of amyloid-ss at the human blood-brain barrier (P4.083)

CONCLUSION: Our results using a new human in vitro BBB model suggest that BCRP act to prevent the blood-borne Aß from entering brain at the human BBB. Study Supported by: Research grant (26461271) from the Japan Society for the Promotion of Science, Tokyo, Japan.Disclosure: Dr. Sano has nothing to disclose. Dr. Abe has nothing to disclose. Dr. Nishihara has nothing to disclose. Dr. Takeshita has nothing to disclose. Dr. Kanda has nothing to disclose.

Source: Neurology - April 8, 2015 Category: Neurology Authors: Sano, Y., Abe, M., Nishihara, H., Takeshita, Y., Kanda, T. Tags: Aging, Dementia, Cognitive, and Behavioral Neurology: Basic and Pre-clinical Studies Source Type: research