Etiology of Sudden Cardiac Arrest and Death in US Competitive Athletes: A 2-Year Prospective Surveillance Study
Conclusions: The etiology of SCA/D in competitive athletes involves a wide range of clinical disorders. More robust reporting mechanisms, standardized autopsy protocols, and accurate etiology data are needed to better inform prevention strategies. (Source: Clinical Journal of Sport Medicine)
Source: Clinical Journal of Sport Medicine - July 1, 2020 Category: Sports Medicine Tags: Original Research Source Type: research

Intracranial vessel wall MR imaging of an intradural vertebral artery dissection
We present a case of a 37-year-old male with a history of a Wolff- Parkinson-White presenting with acute onset of nausea, vertigo, and left body hemisensory loss of pain and temperature. A conventional brain MR identified an acute infarct in the right lateral medulla, concordant with clinical symptoms of a Wallenberg syndrome. (Source: Clinical Imaging)
Source: Clinical Imaging - June 16, 2020 Category: Radiology Authors: Kofi-Buaku Atsina, Aaron Rothstein, Steven R. Mess é, Jae W. Song Tags: Neuroradiology Source Type: research

The Case of Flecainide Toxicity: What to Look for and How to Treat
Flecainide is a class Ic antidysrhythmic agent used to prevent and treat both ventricular and supraventricular tachycardias, including atrial fibrillation, atrioventricular nodal re-entrant tachycardia, and Wolff-Parkinson-White syndrome. Flecainide can cause serious side effects, including cardiac arrest, dysrhythmias, and heart failure. Despite its growing use, the presenting signs and symptoms of flecainide toxicity are not familiar to most clinicians. In particular, our patient's particular presentation of acute kidney injury (AKI) resulting in flecainide accumulation is high risk for missed diagnosis in the emergency ...
Source: The Journal of Emergency Medicine - June 10, 2020 Category: Emergency Medicine Authors: Joshua M. Newson, Cynthia D. Santos, Bradford L. Walters, Brett R. Todd Tags: Selected Topics: Toxicology Source Type: research

Clinical characteristics of challenging catheter ablation procedures in patients with WPW syndrome: A 10 year single-center experience.
CONCLUSIONS: Symptomatic WPW patients with multiple, parahisian, and broad APs had a significantly higher risk of recurrence. In half of the recurrence patients, AP recurrences were confirmed during the acute phase, but were rarely recorded in the very late phase. PMID: 32532584 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - June 8, 2020 Category: Cardiology Authors: Fujino T, De Ruvo E, Grieco D, Scará A, Borrelli A, De Luca L, Panuccio M, Fagagnini A, Bruni G, Sciarra L, Calò L Tags: J Cardiol Source Type: research

Loss of ventricular preexcitation during noninvasive testing does not exclude high-risk accessory pathways: A multicenter study of WPW in children
Abrupt loss of ventricular preexcitation on noninvasive evaluation, or nonpersistent preexcitation, in Wolff-Parkinson-White syndrome (WPW) is thought to indicate a low risk of life-threatening events. (Source: Heart Rhythm)
Source: Heart Rhythm - May 30, 2020 Category: Cardiology Authors: Carolina A. Escudero, Scott R. Ceresnak, Kathryn K. Collins, Robert H. Pass, Peter F. Aziz, Andrew D. Blaufox, Michel Cabrera Ortega, Bryan C. Cannon, Mitchell Cohen, Brynn E. Dechert, Anne M. Dubin, Kara S. Motonaga, Michael R. Epstein, Christopher C. Er Source Type: research

Loss of Ventricular Pre-excitation During Non-invasive Testing Does Not Exclude High-Risk Accessory Pathways: A Multicenter Study of WPW in Children
Abrupt loss of ventricular pre-excitation on non-invasive evaluation, or non-persistent pre-excitation, in Wolff-Parkinson-White syndrome (WPW) is thought to indicate a low risk of life-threatening events. (Source: Heart Rhythm)
Source: Heart Rhythm - May 30, 2020 Category: Cardiology Authors: Carolina A. Escudero, Scott R. Ceresnak, Kathryn K. Collins, Robert H. Pass, Peter F. Aziz, Andrew D. Blaufox, Michel Cabrera Ortega, Bryan C. Cannon, Mitchell Cohen, Brynn E. Dechert, Anne M. Dubin, Kara S. Motonaga, Michael R. Epstein, Christopher C. Er Source Type: research

Increased pre-excitation in ECG improves accuracy of algorithms for accessory pathway localization in Wolff-Parkinson-White syndrome.
CONCLUSIONS: Greater pre-excitation in ECG improved the accuracy of the traditional AP localizing algorithms. The algorithm designed to use maximally pre-excited ECG has the best accuracy. Preferably maximally pre-excited ECGs should be used in clinical practice to facilitate the ablation procedure. PMID: 32438794 [PubMed - as supplied by publisher] (Source: Polish Heart Journal)
Source: Polish Heart Journal - May 19, 2020 Category: Cardiology Authors: Moskal P, Bednarski A, Kiełbasa G, Czarnecka D, Jastrzębski M Tags: Kardiol Pol Source Type: research

Wolff Parkinson White and recreational (meth)amphetamine use: a potentially lethal combination
. (Source: Acta Clinica Belgica)
Source: Acta Clinica Belgica - April 2, 2020 Category: General Medicine Authors: B. Aspeslagh P. Calle J. De Pooter Source Type: research

Prevalence and Outcomes of Patients with Wolff-Parkinson-White in Danon Disease: Results of a Retrospective Analysis
This study examined the prevalence of WPW and associated outcomes in a cohort of patients with Danon Disease. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: M. Brooks, D. Darden, K. Hong, V. Escobedo, B. Le, C. Bougalt, E. Adler Tags: (367) Source Type: research

Ablation for Wolff-Parkinson-White syndrome: a life ‑saving procedure.
Ablation for Wolff-Parkinson-White syndrome: a life‑saving procedure. Kardiol Pol. 2020 Mar 25;78(3):177-178 Authors: Giaccardi M PMID: 32218386 [PubMed - as supplied by publisher] (Source: Polish Heart Journal)
Source: Polish Heart Journal - March 24, 2020 Category: Cardiology Authors: Giaccardi M Tags: Kardiol Pol Source Type: research

[Research Articles] Noninvasive localization of cardiac arrhythmias using electromechanical wave imaging
This study evaluates the accuracy of EWI for localization of various arrhythmias in all four chambers of the heart before catheter ablation. Fifty-five patients with an accessory pathway (AP) with Wolff-Parkinson-White (WPW) syndrome, premature ventricular complexes (PVCs), atrial tachycardia (AT), or atrial flutter (AFL) underwent transthoracic EWI and 12-lead ECG. Three-dimensional (3D) rendered EWI isochrones and 12-lead ECG predictions by six electrophysiologists were applied to a standardized segmented cardiac model and subsequently compared to the region of successful ablation on 3D electroanatomical maps generated b...
Source: Science Translational Medicine - March 24, 2020 Category: Biomedical Science Authors: Grubb, C. S., Melki, L., Wang, D. Y., Peacock, J., Dizon, J., Iyer, V., Sorbera, C., Biviano, A., Rubin, D. A., Morrow, J. P., Saluja, D., Tieu, A., Nauleau, P., Weber, R., Chaudhary, S., Khurram, I., Waase, M., Garan, H., Konofagou, E. E., Wan, E. Y. Tags: Research Articles Source Type: research

Success rate and safety of catheter ablation in preexcitation syndrome: A comparison between adult and pediatric patients.
CONCLUSIONS: Ablation in children and adults are equally effective with respect to short-term clinical observation. PMID: 32207846 [PubMed - as supplied by publisher] (Source: Cardiology Journal)
Source: Cardiology Journal - March 23, 2020 Category: Cardiology Authors: Pietrzak R, Franke M, Gawałko M, Lodziński P, Balsam P, Grabowski M, Werner B Tags: Cardiol J Source Type: research

Histological examination of the potential arrhythmic substrates in the setting of Ebstein's malformation.
Abstract Cardiac arrhythmias, notably Wolff-Parkinson-White syndrome, are known to represent a major issue in patients with Ebstein's malformation of the tricuspid valve. Abnormal conducting circuits, however, can also be produced by pathways extending either from the atrioventricular node or the ventricular components of the atrioventricular conduction axis, direct to the crest of the muscular ventricular septum. We hoped to provide further information on the potential presence of such pathways by investigations of six autopsied examples of Ebstein's malformation. All were studied by histological sectioni...
Source: Journal of Anatomy - March 1, 2020 Category: Anatomy Authors: Sánchez-Quintana D, Cabrera JA, Picazo-Angelin B, Cabrera A, Anderson RH Tags: J Anat Source Type: research

“If at first you don’t succeed”: repeat ablations in young patients with supraventricular tachycardia
ConclusionsIn this report of 55 young patients who underwent repeat ablation for WPW and/or SVT, acute and mid-term success rates were 87% and 80%, respectively. These data may help inform decision-making when caring for patients with persistent or recurrent SVT after an initial ablation attempt. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - December 12, 2019 Category: Cardiology Source Type: research

[Electrophysiological properties of asymptomatic children and adolescents with the Wolff-Parkinson-White electrocardiographic pattern].
CONCLUSION: High-risk antegrade conduction properties are exhibited by more than one-quarter of asymptomatic children and adolescents with WPW. Ablation should be considered as a first-line therapy in asymptomatic children and adolescents with high-risk WPW. PMID: 31802767 [PubMed - in process] (Source: Turk Kardiyoloji Dernegi arsivi)
Source: Turk Kardiyoloji Dernegi arsivi - November 30, 2019 Category: Cardiology Authors: Koca S, Akdeniz C, Tuzcu V Tags: Turk Kardiyol Dern Ars Source Type: research