Martin Burke: Replacing Lost Proteins to Treat Disease
As a medical student, Martin Burke, M.D., Ph.D., helped care for a young college student with cystic fibrosis (CF), an inherited disease that affects the body’s ability to make sweat and mucus. Dr. Burke had just studied CF in class, so he relayed what he had learned to her. He had a lot of information to give—doctors and researchers know the exact amino acid changes in an ion channel protein called cystic fibrosis transmembrane conductance regulator (CFTR) that cause CF.
Credit: UIUC News Bureau, Fred Zwicky.
“At one point in the conversation, she stopped me and said, ‘It sounds like you know exactly what’s...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 10, 2024 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Tools and Techniques Medicines Profiles Source Type: blogs
DecisionRx Announces $100 Million Credit Facility with Carlyle
Funds to Support Delivery of DecisionRx’s Comprehensive Medication Therapy Optimization Program
DecisionRx, Inc., a value-based healthcare company reducing the cost of care by helping physicians eliminate medication failure, today announced that it has entered into a $100 million credit facility with global investment firm Carlyle.
The financing will support the cost-bearing that is key to DecisionRx’s unique business model: DecisionRx can assume the full cost of delivering Medication Therapy Optimization to patients of Accountable Care Organizations, Medicare Advantage Plans, and self-insured employers. The facility...
Source: EMR and HIPAA - February 5, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Akhil Bansal Aon Aon Securities Carlyle DecisionRx Health IT Funding Health IT Fundings Health IT Investment James Wallace Sourna Daneshvar Source Type: blogs
Six species of deer
The UK has six species of deer living wild.
Red Deer, Cervus elaphus – true native species found in Scotland, the Lake District, and on Exmoor, as well as Northern Ireland, much larger than all other deer, and indeed any other British mammal. Distinctive rusty, red-brown colour in summer. Short tail and pale rump patch.
Red Deer, English Lake District, very old, low-light, scanned film photo
Roe Deer, Capreolus capreolus – true native species present across the whole of England, Scotland, and Wales. Rusty red coat in summer, grey-ish in winter. Prominent white rump and no tail. Females have a small
tush or tuft...
Source: David Bradley Sciencebase - Songs, Snaps, Science - January 8, 2024 Category: Science Authors: David Bradley Tags: Vertebrates Source Type: blogs
Executive Accountability in Emergencies: Lessons from the COVID-19 Pandemic
Janina Boughey (University of New South Wales), Executive Accountability in Emergencies: Lessons from the COVID-19 Pandemic (UNSW L. Rsch. Paper No. 23-45) (2022): The COVID-19 pandemic revealed many things about our society —both negative and positive. One thing that the past... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - December 9, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
3D Printing In Medicine And Healthcare – The Ultimate List
3D printing has demonstrated huge potential for the future of medicine in the previous years, and its development is unstoppable. See the impressive list of 3D-printed healthcare materials and medical equipment below!
How does 3D printing in medicine work?
3D printing in medicine is part of the innovative process called additive manufacturing, which means producing three-dimensional solid objects from a digital file. How the technology works, we explained in our article on bioprinting here.
As technology evolves, researchers work on various solutions. For example, engineers from the University of Buffalo have ...
Source: The Medical Futurist - November 7, 2023 Category: Information Technology Authors: berci.mesko Tags: 3D Printing Biotechnology Future of Medicine Healthcare Design Medical Education Personalized Medicine 3d printed biomaterial tissue engineering Video bioprinting GC1 Innovation Source Type: blogs
Out of Control Health Costs or a Broken Society
Flawed Accounting for the US Health Spending Problem
By Jeff Goldsmith
Source: OECD, Our World in Data
Late last year, I saw this chart which made my heart sink. It compared US life expectancy to its health spending since 1970 vs. other countries. As you can see, the US began peeling off from the rest of the civilized world in the mid-1980’s. Then US life expectancy began falling around 2015, even as health spending continued to rise. We lost two more full years of life expectancy to COVID. By the end of 2022, the US had given up 26 years-worth of progress in life expecta...
Source: The Health Care Blog - October 9, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy COVID Drug Overdoses gun violence Hospitals Jeff Goldsmith Maternal mortality Mental Health Obesity Poverty Regional Economy Society Source Type: blogs
Out of Control Health Costs or a Broken Society
Flawed Accounting for the US Health Spending Problem
By Jeff Goldsmith
Source: OECD, Our World in Data
Late last year, I saw this chart which made my heart sink. It compared US life expectancy to its health spending since 1970 vs. other countries. As you can see, the US began peeling off from the rest of the civilized world in the mid-1980’s. Then US life expectancy began falling around 2015, even as health spending continued to rise. We lost two more full years of life expectancy to COVID. By the end of 2022, the US had given up 26 years-worth of progress in life expectancy gains. Adding four more ...
Source: The Health Care Blog - October 9, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy COVID Drug Overdoses gun violence Hospitals Jeff Goldsmith Maternal mortality Mental Health Obesity Poverty Regional Economy Society Source Type: blogs
Ibex Raises $55 Million in Series C Funding to Drive Global Adoption of AI for Cancer Diagnosis
Led by 83North, This Round of Financing Brings Total Funding to Over $100 Million
Ibex Medical Analytics (Ibex), the leader in AI-powered cancer diagnostics, today announced it has closed a $55 million Series C financing round led by 83North. Additional participants in the round were Sienna Venture Capital and existing investors in the company, Octopus Ventures, aMoon, Planven Entrepreneur Ventures, and Dell Technologies Capital. The financing brings total funding to over $100 million since Ibex’s inception in 2016.
Ibex is transforming cancer diagnostics with AI-powered solutions that help pathologists improve the...
Source: EMR and HIPAA - September 25, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT 83North aMoon Dell Technologies Capital Galen Gil Goren Health IT Funding Health IT Fundings Health IT Investment Ibex Ibex Medical Analytics Joseph Mossel Octopus Ventures Planven Entrepreneur V Source Type: blogs
Ignoring High Blood Pressure After 60? Study Warns of a 42% Increase in Dementia Risk
Conclusion
The study brings to light startling data: untreated high blood pressure in people over 60 raises their risk of dementia by 42%.
It’s a finding that shouldn’t be ignored, considering the societal burden dementia poses.
Even when compared to individuals with treated hypertension, the risks remain elevated.
In essence, this compelling study highlights the critical need for treating high blood pressure in later life.
Doing so could significantly lower the risk of dementia, providing not just longer but also higher-quality lives for older adults.
Read next: High Blood Pressure In Your...
Source: The EMT Spot - September 14, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
“To do nothing is not an option”: The NHS Confederation releases digital mental health whitepaper
This report highlights practical and achievable suggested discussion points that aim to bridge this gap and make a difference. They include a call for a wider and deeper national conversation on digital mental health and its future and consider developing effective ways of scaling digital mental health solutions in local and national solutions.
Why digital mental health?
Improved access: Digital mental health solutions can overcome geographical barriers, making mental health services more accessible to people in remote areas, those with limited mobility, and those who would prefer not to have in-person visits…
Early ...
Source: SharpBrains - September 12, 2023 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation digital digital mental health mental health services mental healthcare NHS Confederation technologies Source Type: blogs
Towards an Australian Housing and Homelessness Strategy: Understanding National Approaches in Contemporary Policy
Chris Martin (City Futures Research Center), Julie Lawson (RMIT University), Vivienne Milligan (University of New South Wales), Chris Hartley (University of New South Wales), Towards an Australian Housing and Homelessness Strategy: Understanding National Approaches in Contemporary Policy (2023): This research... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - August 20, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
Current resources about COVID-19
(Last updated 19th June 2023)IntroductionDuring lockdown I maintained a set of blogposts linking to resources about COVID. I have not updated those for some time, and have now decided that they are no longer needed. I have added the word " Archived " to the start of each page title, and tried to make it clear that they are no longer updated. Of course, COVID-19 has not gone away, and has become one of the infectious diseases that is with us always. So, I think although those older posts are no longer useful, a current list of resources might be. So, here is a shorter...
Source: Browsing - June 19, 2023 Category: Databases & Libraries Tags: COVID-19 Source Type: blogs
Ask and Tell: Family Caregiving as a Social Determinant of Health
I sat in front of my doctor for the first time since before the pandemic. She was concerned: “You’re way overdue for a couple of screening tests and a vaccination.” I explained that between Covid waves and caregiving for my mom, I’d had to cancel and reschedule the most the screening test at least 3 times. And, caregiving for my mom was becoming more intense, which was going to create more challenges. She asked if anyone was helping me. I explained that my husband is a huge help. But I’m the only adult child who lives within driving distance. And just within the past few months there’s been a couple of falls, a...
Source: EMR and HIPAA - June 14, 2023 Category: Information Technology Authors: Geri Lynn Baumblatt Tags: Clinical Communication and Patient Experience Healthcare IT Hospital - Health System care partner family caregiver patient clinician relationship patient engagement SDOH Social Determinants of Health Source Type: blogs
75 year old with 24 hours of chest pain, STEMI negative
Written by Jesse McLaren A 75 year old
with a history of CABG called EMS after 24 hours of chest pain. HR 40, BP
135/70, RR16, O2 100%. Here ’s the paramedic ECG (digitized by PMcardio). What
do you think? There ’s sinus
bradycardia, normal conduction, normal axis, delayed R wave progression, and
normal voltages. There are inferior Q waves and lead III has mild concave ST
elevation, with subtle reciprocal ST depression in I/aVL. This is diagnostic of
inferior OMI, likely from the RCA. The patient has a hi story of CABG so some of
these changes could be old, but with ongoing chest pain and bradycardia in a
hig...
Source: Dr. Smith's ECG Blog - June 8, 2023 Category: Cardiology Authors: Jesse McLaren Source Type: blogs
Fight Aging! Newsletter, June 5th 2023
In conclusion, higher BMR might reduce lifespan. The underlying pathways linking to major causes of death and relevant interventions warrant further investigation.
Betting Against Progress Turns Out Poorly, But Can Work in the Short Term in a Slow Field
https://www.fightaging.org/archives/2023/06/betting-against-progress-turns-out-poorly-but-can-work-in-the-short-term-in-a-slow-field/
Setting oneself up as a spokesperson for "we will not achieve this goal", as the fellow noted here is choosing to do, is a bet against technological progress. A glance at any few decade period in the past two hundred yea...
Source: Fight Aging! - June 4, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
