Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research

Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research

Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research

Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research

Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research

Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research

Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Cancers, Vol. 16, Pages 1013: Feasibility of Introducing a Prehabilitation Program into the Care of Gynecological Oncology Patients & mdash;A Single Institution Experience
This study aims to assess the feasibility of implementing a multimodal prehabilitation program into the standard care of gynecological oncology patients at an academic hospital in terms of recruitment, adherence, and safety, which were assessed by the number of patients eligible, recruitment rate, participation rate, and adherence to individual modalities. Data were derived from the F4S PREHAB trial, a single-center stepped-wedge trial implementing a multimodal prehabilitation program among various surgical specialties. All patients undergoing elective surgery as part of treatment for ovarian, uterine, and vulvar cancer at...
Source: Cancers - February 29, 2024 Category: Cancer & Oncology Authors: Jo ëlle Dhanis Dieuwke Strijker Luuk D. Drager Maaike van Ham Cornelis J. H. M. van van Laarhoven Johanna M. A. Pijnenborg Anke Smits Baukje van den van den Heuvel Tags: Article Source Type: research

Genetics and beyond: Precision Medicine Real-World Data for Patients with Cervical, Vaginal or Vulvar Cancer in a Tertiary Cancer Center
Int J Mol Sci. 2024 Feb 16;25(4):2345. doi: 10.3390/ijms25042345.ABSTRACTAdvances in molecular tumor diagnostics have transformed cancer care. However, it remains unclear whether precision oncology has the same impact and transformative nature across all malignancies. We conducted a retrospective analysis of patients with human papillomavirus (HPV)-related gynecologic malignancies who underwent comprehensive molecular profiling and subsequent discussion at the interdisciplinary Molecular Tumor Board (MTB) of the University Hospital, LMU Munich, between 11/2017 and 06/2022. We identified a total cohort of 31 patients diagno...
Source: Molecular Medicine - February 24, 2024 Category: Molecular Biology Authors: Fabian B T Kraus Elena Sultova Kathrin Heinrich Andreas Jung C Benedikt Westphalen Christina V Tauber J örg Kumbrink Martina Rudelius Frederick Klauschen Philipp A Greif Alexander K önig Anca Chelariu-Raicu Bastian Czogalla Alexander Burges Sven Mahner Source Type: research