Epidemiology of vulvar cancer in Croatia
CONCLUSION: In the studied period, the incidence of invasive vulvar cancer in Croatia was stable. Age-standardized rates (for all-ages, under 60, and over 60 years of age) increased, but the increase did not reach the level of statistical significance. The pattern in younger and older age groups was the same. The mortality rates over the last decade were stable.PMID:37131312 | PMC:PMC10183957 | DOI:10.3325/cmj.2023.64.103 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - May 3, 2023 Category: General Medicine Authors: Irena Bari šić Petra Čukelj Ivana Brki ć Biloš Mario Šekerija Source Type: research
Epidemiology of vulvar cancer in Croatia
CONCLUSION: In the studied period, the incidence of invasive vulvar cancer in Croatia was stable. Age-standardized rates (for all-ages, under 60, and over 60 years of age) increased, but the increase did not reach the level of statistical significance. The pattern in younger and older age groups was the same. The mortality rates over the last decade were stable.PMID:37131312 | PMC:PMC10183957 | DOI:10.3325/cmj.2023.64.103 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - May 3, 2023 Category: General Medicine Authors: Irena Bari šić Petra Čukelj Ivana Brki ć Biloš Mario Šekerija Source Type: research
Epidemiology of vulvar cancer in Croatia
CONCLUSION: In the studied period, the incidence of invasive vulvar cancer in Croatia was stable. Age-standardized rates (for all-ages, under 60, and over 60 years of age) increased, but the increase did not reach the level of statistical significance. The pattern in younger and older age groups was the same. The mortality rates over the last decade were stable.PMID:37131312 | PMC:PMC10183957 | DOI:10.3325/cmj.2023.64.103 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - May 3, 2023 Category: General Medicine Authors: Irena Bari šić Petra Čukelj Ivana Brki ć Biloš Mario Šekerija Source Type: research
Mammary-like adenocarcinoma of the vulva: a rare case report with next generation sequencing
We report a case of an 88-year-old woman affected by MLAV with comedo-like features, with a detailed description of the pathological, immunohistochemical and molecular features. Immunohistochemistry (IHC) showed strong staining for cytokeratin 7, GATA3, androgen receptor, GCFPD15, and weak staining for mammaglobin; no staining for Her-2 was found. The proliferation index (Ki-67) was 15%. Molecular testing detected a pathogenic mutation of the AKT1 gene, a likely pathogenic frameshift insertion of the JAK1 gene, and two likely pathogenic frameshift deletions of the KMT2C gene; in addition, two variants of unknown significan...
Source: Pathologica - April 28, 2023 Category: Pathology Authors: Renato Lobrano Alessandra Manca Maria Cristina Sini Giuseppe Palmieri Marco Petrillo Antonio Cossu Panagiotis Paliogiannis Source Type: research
