The Role of Urothelial Cancer-Associated 1 in Gynecological Cancers
Curr Issues Mol Biol. 2024 Mar 21;46(3):2772-2797. doi: 10.3390/cimb46030174.ABSTRACTGynecological cancers (GC) represent some of the most frequently diagnosed malignancies in women worldwide. Long-non-coding RNAs (lncRNAs) are regulatory RNAs increasingly being recognized for their role in tumor progression and metastasis in various cancers. Urothelial cancer-associated 1 (UCA1) is a lncRNA, first found deregulated in bladder cancer, and many studies have exposed its oncogenic effects in more tumors since. However, the role of UCA1 in gynecological malignancies is still unclear. This review aims to analyze and define the ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Eleni Nousiopoulou Kleio Vrettou Christos Damaskos Nikolaos Garmpis Anna Garmpi Panagiotis Tsikouras Nikolaos Nikolettos Konstantinos Nikolettos Iason Psilopatis Source Type: research

The Role of Urothelial Cancer-Associated 1 in Gynecological Cancers
Curr Issues Mol Biol. 2024 Mar 21;46(3):2772-2797. doi: 10.3390/cimb46030174.ABSTRACTGynecological cancers (GC) represent some of the most frequently diagnosed malignancies in women worldwide. Long-non-coding RNAs (lncRNAs) are regulatory RNAs increasingly being recognized for their role in tumor progression and metastasis in various cancers. Urothelial cancer-associated 1 (UCA1) is a lncRNA, first found deregulated in bladder cancer, and many studies have exposed its oncogenic effects in more tumors since. However, the role of UCA1 in gynecological malignancies is still unclear. This review aims to analyze and define the ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Eleni Nousiopoulou Kleio Vrettou Christos Damaskos Nikolaos Garmpis Anna Garmpi Panagiotis Tsikouras Nikolaos Nikolettos Konstantinos Nikolettos Iason Psilopatis Source Type: research

The Role of Urothelial Cancer-Associated 1 in Gynecological Cancers
Curr Issues Mol Biol. 2024 Mar 21;46(3):2772-2797. doi: 10.3390/cimb46030174.ABSTRACTGynecological cancers (GC) represent some of the most frequently diagnosed malignancies in women worldwide. Long-non-coding RNAs (lncRNAs) are regulatory RNAs increasingly being recognized for their role in tumor progression and metastasis in various cancers. Urothelial cancer-associated 1 (UCA1) is a lncRNA, first found deregulated in bladder cancer, and many studies have exposed its oncogenic effects in more tumors since. However, the role of UCA1 in gynecological malignancies is still unclear. This review aims to analyze and define the ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Eleni Nousiopoulou Kleio Vrettou Christos Damaskos Nikolaos Garmpis Anna Garmpi Panagiotis Tsikouras Nikolaos Nikolettos Konstantinos Nikolettos Iason Psilopatis Source Type: research

The Role of Urothelial Cancer-Associated 1 in Gynecological Cancers
Curr Issues Mol Biol. 2024 Mar 21;46(3):2772-2797. doi: 10.3390/cimb46030174.ABSTRACTGynecological cancers (GC) represent some of the most frequently diagnosed malignancies in women worldwide. Long-non-coding RNAs (lncRNAs) are regulatory RNAs increasingly being recognized for their role in tumor progression and metastasis in various cancers. Urothelial cancer-associated 1 (UCA1) is a lncRNA, first found deregulated in bladder cancer, and many studies have exposed its oncogenic effects in more tumors since. However, the role of UCA1 in gynecological malignancies is still unclear. This review aims to analyze and define the ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Eleni Nousiopoulou Kleio Vrettou Christos Damaskos Nikolaos Garmpis Anna Garmpi Panagiotis Tsikouras Nikolaos Nikolettos Konstantinos Nikolettos Iason Psilopatis Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research

Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research

Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research

Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research

Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research

Update on the Sentinel Node Procedure in Vulvar Cancer
In conclusion, the SN procedure is an established procedure in early-stage VSCC, although optimization of the technique, pathologic workup, indications, and treatment in the setting of metastatic disease are the subject of ongoing research.PMID:38503055 | DOI:10.6004/jnccn.2024.7002 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Willemijn L van der Kolk Joost Bart Ate J G van der Zee Maaike H M Oonk Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research