Fight Aging! Newsletter, August 24th 2020
We report that electrical stimulation (ES) stimulation of post-stroke aged rats led to an improved functional recovery of spatial long-term memory (T-maze), but not on the rotating pole or the inclined plane, both tests requiring complex sensorimotor skills. Surprisingly, ES had a detrimental effect on the asymmetric sensorimotor deficit.
Histologically, there was a robust increase in the number of doublecortin-positive cells in the dentate gyrus and SVZ of the infarcted hemisphere and the presence of a considerable number of neurons expressing tubulin beta III in the infarcted area. Among the genes that were unique...
Source: Fight Aging! - August 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Luciferase Visualization of Age-Related Loss of Mitochondrial Membrane Potential in Mice
Researchers here demonstrate a way to visualize mitochondrial membrane potential, a measure of mitochondrial function, in living animals. A tailored genetic modification causes luciferase activity to correlate with mitochondrial membrane potential: engineered mice with better functioning mitochondria glow more brightly. This, in principle, allows for rapid testing of approaches that will restore mitochondrial function in old mice.
Tiny factories float inside our cells and provide them with almost all the energy they need: the mitochondria. Their effectiveness decreases when we get older. Mitochondria are almost li...
Source: Fight Aging! - August 18, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Will vitamin supplements make my hair grow? Episode 224
Welcome to the Beauty Brains, a show where real cosmetic chemists answer your beauty product questions and give you an insider’s look at the cosmetic industry.
Hosts: Perry Romanowski.
On today’s show we’re going to answer questions about…
Whether beauty supplements can make hair & skin look better
What exactly is skin pH
And whether you have to mix products exactly to get them to work?
Beauty Science News
Does SPF 100 work better than SPF 50?
CIR releases latest findings
Beauty Questions
Question 1 – Clare – I want to grow my hair longer – it’s taking too long – Vita gummy hair gr...
Source: thebeautybrains.com - June 19, 2020 Category: Consumer Health News Authors: Perry Romanowski Tags: Podcast Source Type: blogs
Fight Aging! Newsletter, June 1st 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - May 31, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Do plant extracts work in skin care products – episode 222
Welcome to the Beauty Brains, a show where real cosmetic chemists answer your beauty product questions and give you an insider’s look at the cosmetic industry. This is Episode 222. Yes, that’s a palindrome! Yeah. I’m your host, Perry Romanowski and with me today is…well, it’s just me. Valerie is off today but she’ll be back next week.
Meanwhile on today’s show I’m going to be answering questions about…
Whether the SkinDupes AI is a reliable way to pick skin care products?
Can you combine Vitamin C and Niacinamide?
Do blue light serums provide any extra benefit?
Whether it’s worth it to gro...
Source: thebeautybrains.com - May 30, 2020 Category: Consumer Health News Authors: Perry Romanowski Tags: Podcast Source Type: blogs
Do plant extracts work in skin care products – episode 222
Welcome to the Beauty Brains, a show where real cosmetic chemists answer your beauty product questions and give you an insider’s look at the cosmetic industry. This is Episode 222. Yes, that’s a palindrome! Yeah. I’m your host, Perry Romanowski and with me today is…well, it’s just me. Valerie is off today but she’ll be back next week.
Meanwhile on today’s show I’m going to be answering questions about…
Whether the SkinDupes AI is a reliable way to pick skin care products?
Can you combine Vitamin C and Niacinamide?
Do blue light serums provide any extra benefit?
Whether it’s worth it to gro...
Source: thebeautybrains.com - May 30, 2020 Category: Consumer Health News Authors: Perry Romanowski Tags: Podcast Source Type: blogs
Reviewing the Prospects for Nicotinamide Mononucleotide Supplementation to Raise NAD+ Levels and Improve Health
A fair amount of effort is presently put towards the exploration of supplements derived from vitamin B3 compounds (nicotinamide, niacin, nicotinamide riboside) that act as precursors to enable the manufacture of nicotinamide adenine dinucleotide (NAD). NAD is an important component in mitochondrial activity, and levels decline with age. Some portion of the loss of mitochondrial function, implicated in the progression of many age-related conditions, is due to NAD insufficiency. There is a rich history of the use of high doses of vitamin B3 as an intervention, most of it predating modern understanding of the role of NAD in m...
Source: Fight Aging! - May 29, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, May 25th 2020
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation.
Lin28 as a Target for Nerve Regeneration
https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/
Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitochondr...
Source: Fight Aging! - May 24, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Loss of NAD+ Implicated in Age-Related Circadian Rhythm Dysfunction
As for other aspects of metabolic regulation, circadian rhythm becomes increasingly disrupted with age. Researchers here provide evidence for falling NAD+ levels to be a proximate cause of this issue. NAD+ is important in the core activity of mitochondria, generation of energy store molecules to power cellular operations, but also acts on numerous other processes in the cell. Unfortunately the various mechanisms of synthesis and recycling of NAD+ falter as tissues age, though it is an open question as to how much of this is a matter of failing to maintain fitness versus more inexorable processes of aging. Data suggests tha...
Source: Fight Aging! - May 22, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, May 18th 2020
This study provides direct evidence for the contribution of gut microbiota to the cognitive decline during normal aging and suggests that restoring microbiota homeostasis in the elderly may improve cognitive function.
On Nutraceutical Senolytics
https://www.fightaging.org/archives/2020/05/on-nutraceutical-senolytics/
Nutraceuticals are compounds derived from foods, usually plants. In principle one can find useful therapies in the natural world, taking the approach of identifying interesting molecules and refining them to a greater potency than naturally occurs in order to produce a usefully large therap...
Source: Fight Aging! - May 17, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Ten Weeks of Resistance Training in 60-Year-Olds Doubles NAD+ Levels in Muscle Tissue
When looking at any of the work presently taking place on improving metabolism in older individuals, whether by stress response upregulation, or by improving mitochondrial function, it is always worth checking the human data, where it exists, to compare the effect size with that of exercise. This open paper is a useful resource when comparing exercise to the class of approaches that fairly directly increase levels of NAD+/NADH. These molecules are involved in mitochondrial function, and for various reasons - decline in recycling, decline in synthesis - become less available with age.
A number of supplements and trea...
Source: Fight Aging! - May 13, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Monat MLM Beauty Products – Are they remarkable? Episode 218
Welcome to the Beauty Brains, a show where real cosmetic chemists answer your beauty product questions and give you an insider’s look at the cosmetic industry. This is Episode 218.
Hosts: Valerie George and Perry Romanowski.
On today’s show we’re going to be answering beauty questions about…
How do magnetic face masks work?
Do Rodan + Field products really live up to their claims?
Are Monat’s hair products really that special?
Can Monat cleanser remove a marker mark?
Beauty Industry news
Most popular beauty products during quarantine
Recall alert
Wyndmere Naturals Recalls Birch Sweet Essential Oil and Ache...
Source: thebeautybrains.com - April 22, 2020 Category: Consumer Health News Authors: Perry Romanowski Tags: Podcast Source Type: blogs
Monat MLM Beauty Products – Are they remarkable? Episode 218
Welcome to the Beauty Brains, a show where real cosmetic chemists answer your beauty product questions and give you an insider’s look at the cosmetic industry. This is Episode 218.
Hosts: Valerie George and Perry Romanowski.
On today’s show we’re going to be answering beauty questions about…
How do magnetic face masks work?
Do Rodan + Field products really live up to their claims?
Are Monat’s hair products really that special?
Can Monat cleanser remove a marker mark?
Beauty Industry news
Most popular beauty products during quarantine
Recall alert
Wyndmere Naturals Recalls Birch Sweet Essential Oil and Ache...
Source: thebeautybrains.com - April 22, 2020 Category: Consumer Health News Authors: Perry Romanowski Tags: Podcast Source Type: blogs
Does Beverly Hills MD Brow Serum work and other beauty questions? episode 213
We have a lot of beauty questions to answer today, including:
What do we think of the Beverly Hills MD brow serum
Are lash tints safe?
Why do anti-aging ingredients affect skin color?
Why do dermatologists keep saying hyaluronic acid is pointless?
Perry and Valerie are under self imposed quarantine! But we’re still recording.
Beauty science news
Are cosmetics going to be more regulated?
The spokesperson from the EWG (who likes this new legislation by the way) said the following about the cosmetics industry. “…no category of consumer products is subject to less government oversight than cosmetics and o...
Source: thebeautybrains.com - March 19, 2020 Category: Consumer Health News Authors: Perry Romanowski Tags: Podcast Source Type: blogs
Can I use a facial cleanser as a shampoo? Episode 212
Beauty Questions covered
We have a lot of beauty questions to answer today, including:
What are the best facial moisturizers for sensitive skin?
Is there a big difference between facial cleansers and shampoo?
Will castor oil help your hair grow?
How does someone become a cosmetic chemist? (Audio)
Beauty Science News
How is the spread of the coronavirus affecting the beauty industry?
You can’t turn on any news channel without hearing about the coronavirus, and that includes the beauty news! The coronavirus is doing more to the beauty industry than impacting stocks; supply chains for all aspects of the beauty indu...
Source: thebeautybrains.com - March 11, 2020 Category: Consumer Health News Authors: Perry Romanowski Tags: Podcast Source Type: blogs
