Herpes Zoster Vaccination Reduces Alzheimer's Risk
Evidence exists for herpesvirus infection to increase the risk of suffering Alzheimer's disease. The evidence is mixed, however, with some studies showing no effect. There is some suggestion that the interaction of multiple viruses is the real contributing effect, which is why looking at just one virus type may produce problematic data. Researchers here show that vaccination against herpes zoster reduces Alzheimer's risk, though one might as to whether this is because of reduced viral impact, or because vaccinations can produce a trained immunity effect, reducing chronic inflammation in older people. There is grow...
Source: Fight Aging! - June 2, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

A Long-Awaited Vaccine
by Gertrud U. Rey Almost sixty years have passed since the initial formalin-inactivated respiratory syncytial virus (RSV) vaccine caused enhanced disease in children when they were subsequently infected with the virus. Since then, RSV has continued to be a substantial public health threat to infants, young children, and older people. Although progress in developing a … A Long-Awaited Vaccine Read More » (Source: virology blog)
Source: virology blog - June 1, 2023 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey adjuvant F protein FDA fusion protein GlaxoSmithKline gsk Jason McLellan Pfizer phase III trial pre-fusion F protein pre-fusion spike protein public health respiratory syncytial virus rsv vaccine Source Type: blogs

Featured Health IT Job: Director, Application Development and Integrations
We like to regularly feature a healthcare IT job that might be of interest to readers. Today, we’re featuring the Director, Application Development and Integrations position that was recently posted on Healthcare IT Central. This position was posted by New York eHealth Collaborative and is in Manhattan, New York. Here’s a description of the position: New York eHealth Collaborative (NYeC) is a not-for-profit organization working in partnership with the New York State Department of Health to improve healthcare by collaboratively leading, connecting, and integrating health information exchange across the State. ...
Source: EMR and HIPAA - May 31, 2023 Category: Information Technology Authors: Health IT Jobs Tags: Career and Jobs Healthcare IT Application Development and Integrations Director Jobs Health IT Jobs Healthcare IT Jobs Job Seekers New York eHealth Collaborative New York Health IT Jobs NYeC Source Type: blogs

AI in Healthcare and Life Sciences: Further Adoption Requires Better Data Infrastructure
The following is a guest article by Jon Kimerle, Global Strategic Healthcare Alliances at Pure Storage  The digital transformation of healthcare continues to accelerate, and technologies like artificial intelligence (AI) are predicted to have an increasing impact on efficiency, quality, and scalability of health outcomes.  At present, AI is already driving high-quality, predictive patient care and better outcomes by making connections humans can’t, adding context, and unearthing new insights. The data generated by AI can facilitate early disease detection, personalized medications and care, the prevention of diagnostic...
Source: EMR and HIPAA - May 30, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Analytics/Big Data C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System IT Infrastructure and Dev Ops Security and Privacy Artificial Intelligence Clinical AI Algorithms Cyber Attacks Data A Source Type: blogs

To Improve Vaccination in the Elderly, Target Mechanisms of Aging
That vaccinations decline in effectiveness with advancing age is only one of countless ways in which the underlying mechanisms of aging collectively harm health and resilience in later life. If the urge to improve vaccination efficacy in older individuals turns out to be a major contribution to driving greater investment in the development of means of rejuvenation, therapies that target the causes of aging, then the benefits will extend far beyond this narrow goal. Despite the availability of flu vaccines formulated to better protect older adults, older adults remain disproportionally at-risk for severe infection,...
Source: Fight Aging! - May 30, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Germinal Centers Become Dysfunctional with Age, Impairing the Immune Response
In this study we looked at what was happening to different cell types in the germinal centre, particularly the structure and organisation of the germinal centre across its two functionally distinct zones, to try and understand what causes the reduced germinal centre response with age. What we found is that the T follicular helper cells aren't where they should be and as a result, antibody-producing cells lose essential selection cues. Surprisingly we also uncovered an unknown role for T follicular helper cells in supporting the expansion of follicular dendritic cells in the light zone after vaccination." Having iden...
Source: Fight Aging! - May 29, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, May 29th 2023
In this study, we used a Drosophila model to understand the role of the dec2P384R mutation on animal health and elucidate the mechanisms driving these physiological changes. We found that the expression of the mammalian dec2P384R transgene in fly sleep neurons was sufficient to mimic the short sleep phenotype observed in mammals. Remarkably, dec2P384Rmutants lived significantly longer with improved health despite sleeping less. In particular, dec2P384R mutants were more stress resistant and displayed improved mitochondrial fitness in flight muscles. Differential gene expression analyses went on to reveal several altered tr...
Source: Fight Aging! - May 28, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Reviewing mTOR Inhibition as a Pharmacological Strategy to Modestly Slow Aging
It is arguably the case that we should look at small molecule mTOR inhibitors, such as rapamycin and its descendant rapalog compounds, as the most effective of the calorie restriction mimetic approaches developed to date. The practice of calorie restriction, eating as much as 40% fewer calories while still obtaining optimal levels of micronutrients, produces sweeping changes to metabolism. Some of these, such as increased autophagy and other forms of cellular housekeeping, appear to be beneficial to long-term health. Keeping cells more free of damage leads to a slowing of aging. In mice, that slowing of aging can le...
Source: Fight Aging! - May 23, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Reviewing the Complexity of Immunosenescence
The immune system becomes more inflammatory and less competent with advancing age, undergoing sweeping changes in immune cell characteristics and relative population sizes. The cells, structures, and processes that produce immune cells similarly undergo significant changes. Taken together, this is called immunosenescence, though many researchers choose to break out the inflammatory component of dysfunction into its own category, calling it inflammaging. One of the most important goals for the research community is to find ways to improve immune function in older people. Evidently, the decline of the immune system is...
Source: Fight Aging! - May 22, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Bonus Features – May 21, 2023 – 82% of wearable users willing to share data with their physicians, 81% of Americans trust pharmacists and nurses to diagnose minor illnesses, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Research More than four in five (82%) of wearable device owners are willing to share health data with their physicians, according to a poll conducted by the Connected Health Initiative. Additionally, 87% of users said t...
Source: EMR and HIPAA - May 21, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Health IT Company Healthcare IT AccYouRate BeeKeeperAI Bill Lewkowski Cerner Cognizant Connected Health Initiative Cylera Deloitte Dispatch Health eClinicalWorks eHealth Exchange eHealth Initiative Epic EscrowAI HCTec Hea Source Type: blogs

Advances in Early Diagnosis
This article shows how some surprising technologies are improving the early detection of several conditions. Nutromics continuously monitors the delivery of an antibiotic used to treat sepsis. Eye-tracking from Tobii is used by several of its clients to detect certain kinds of autism as early as twelve months of age. And Cordio Medical is detecting oncoming congestive heart failure (CHF) three weeks in advance of an incident. Minimally Invasive Monitoring Provides Real-Time Measurements Although doctors learn what people have in their bodies most often through blood tests, technologies developed over the past few decades c...
Source: EMR and HIPAA - May 18, 2023 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Clinical Health IT Company Healthcare IT Telemedicine and Remote Monitoring ADOS Agim Beshiri AI Diagnosis Autism CHF Cordio Medical Eye Tracking Eye Tracking Sensors Healthcare Sensors HearO Karen Pierce Source Type: blogs

Featured Health IT Job: Procurement Coordinator
We like to regularly feature a healthcare IT job that might be of interest to readers. Today, we’re featuring the Procurement Coordinator position that was recently posted on Healthcare IT Central. This position was posted by New York eHealth Collaborative and is in New York. Here’s a description of the position: New York eHealth Collaborative (NYeC) is a not-for-profit organization working in partnership with the New York State Department of Health to improve healthcare by collaboratively leading, connecting, and integrating health information exchange across the State. Founded in 2006 by healthcare leaders,...
Source: EMR and HIPAA - May 17, 2023 Category: Information Technology Authors: Health IT Jobs Tags: Career and Jobs Healthcare IT Health IT Jobs Health IT Procurement Healthcare IT Jobs Job Seekers New York eHealth Collaborative New York Health IT Jobs NYeC Procurement Coordinator Source Type: blogs

In an Ideal World, How Much Would We Spend on Health Care? – Part 1
BY BEN WHEATLEY We have heard it said before, and it is no longer shocking to say, that in 2021 the United States spent $4.3 trillion on health care. To put this gaudy number in some perspective, we measure it as a share of our economy and report that health care comprised 18.3% of our gross domestic product. CMS projects that health care will approach 20% of GDP in coming years—one-fifth of everything we buy and sell in this country.  In a recent report, the Health Affairs Council on Health Care Spending and Value said that “it is unclear what percentage of GDP would represent the ideal level to devote to healt...
Source: The Health Care Blog - May 11, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Ben Wheatley Health care spending medical debt Patent Source Type: blogs

In an Ideal World, How Much Would We Spend on Health Care?
BY BEN WHEATLEY We have heard it said before, and it is no longer shocking to say, that in 2021 the United States spent $4.3 trillion on health care. To put this gaudy number in some perspective, we measure it as a share of our economy and report that health care comprised 18.3% of our gross domestic product. CMS projects that health care will approach 20% of GDP in coming years—one-fifth of everything we buy and sell in this country.  In a recent report, the Health Affairs Council on Health Care Spending and Value said that “it is unclear what percentage of GDP would represent the ideal level to devote to h...
Source: The Health Care Blog - May 11, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Ben Wheatley Health care spending medical debt Patent Source Type: blogs

Burden of Pain
BY JAY JOSHI We’re seeing a trend of late, where matters in healthcare once deemed to be civil in nature are turning criminal. We see it for nearly every polarizing health issue, from abortion to opioids. And it’s affecting vulnerable patients the most. We have two separate systems in place, civil and criminal, because we have different standards of behavior. Civil laws determine whether undue harm was caused by one party to another. Criminal laws determine whether someone committed a crime. The threshold is distinctly different. If someone is caught driving ten miles over the designated speed limit, that pers...
Source: The Health Care Blog - May 5, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Abortion Civil Penalties Criminal Law Jay Joshi Opioids Source Type: blogs