Peptoid Oligomers Target Viral Membranes
Researchers at New York University have developed a new method to target many viruses that cause disease. For viruses with a lipid membrane, which includes many that commonly cause disease, this new technique could prove to be fatal. By targeting the lipid membrane, the approach may circumvent the treatment resistance that arises when viruses mutate to alter their surface proteins, which are the most common targets for conventional anti-viral drugs. This new approach is based on a synthetic version of antimicrobial peptides, which are naturally produced by our immune system and can target pathogens such as bacteria and vir...
Source: Medgadget - August 30, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Public Health Source Type: blogs

More Evidence for Vaccination to Reduce Alzheimer's Disease Risk
There is good evidence for the various forms of later life vaccination, such as for herpes zoster or influenza, to reduce the risk of later suffering Alzheimer's disease. One possibility is that people who take the time to obtain a vaccine tend to take better care of their health across the board. Another possibility is that vaccination produces a trained immunity effect that dampens age-related inflammation for a sustained period of time. It may also be the case that suffering from influenza, pneumonia, or similar infectious diseases causes sufficient additional inflammation to move the odds on suffering later neurodegene...
Source: Fight Aging! - August 28, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

DARPA ’s Role in the Development of mRNA Vaccines
Daniel Schoeni (U.S. Air Force JAG Corps), DARPA ’s Role in the Development of mRNA Vaccines (2023): One of the key purposes of the U.S. Department of Defense (DoD) is to deliver war-winning capabilities to soldiers, sailors, marines, airmen, and guardians.... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - August 27, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't ...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Senolytic Vaccine Targeting SAGP Reduces Pathology in a Mouse Model of Alzheimer's Disease
In this study, the research team created an Alzheimer's disease mouse model that mimics a human brain and simulates amyloid-beta-induced Alzheimer's disease pathology. To test the efficacy of the SAGP vaccine, the mice were treated with a control vaccine or the SAGP vaccine at two and four months old. Usually, people in the late stage of Alzheimer's lack anxiety, which means they are not aware of the things around them. The mice who received the vaccine had anxiety, which means that they were more cautious and more aware of things around them - a sign researcher say could indicate a lessening of the disease. In addition, s...
Source: Fight Aging! - August 8, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Biomaterial Injection Combines T Cell and Cancer Vaccine Treatments
Researchers at the Harvard Wyss Institute have developed an anti-cancer biomaterial treatment that combines adoptive T cell therapy and cancer vaccine technology to treat solid tumors. The researchers have called their technique SIVET, which is short for “synergistic in situ vaccination enhanced T cell”. The approach combines local delivery of cytotoxic T cells with longer lasting cancer vaccine technology that engages with the immune system more broadly for long lasting anticancer action. The researchers hope that the technology could lead to improvements in efficacy for immune therapies in treating solid tumors. A...
Source: Medgadget - August 7, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Oncology harvard wyssinstitute Source Type: blogs

Phreesia Acquires MediFind, Reinforcing its Commitment to Patient-Centered Care and Expanding its Offerings to Consumers
Phreesia, a leader in patient intake, outreach, and activation, is pleased to announce it has acquired Comsort, Inc. d/b/a MediFind (MediFind), a health technology company that uses advanced analytics to help patients—especially those with serious, chronic, and rare diseases—find better care faster. MediFind uses machine learning and proprietary algorithms to continuously review medical information across a wide range of datasets, identifying leading doctors in specific conditions and fields based on factors such as their research output, the volume of patients, and standing among their peers. MediFind assigns four lev...
Source: EMR and HIPAA - August 3, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Chronic Care Comsort Inc. David Linetsky Health IT Acquisitions Healthcare M&A MediFind Patrick Howie Phreesia Rare Diseases Rob Weker Source Type: blogs

Is More Physician-Owned Hospitals the Solution to our Health Cost problem?
BY JEFF GOLDSMITH Robert Frost once said,  “Home is where, when you have to go there, they have to take you in.” Increasingly, in our struggling society, that place is your local full service community hospital.  During COVID, if it wasn’t your local hospital standing up testing sites, pumping out vaccinations and working double overtime helping patients breathe, we would have lost several hundred thousand more of our fellow Americans.   But it wasn’t just COVID where hospitals leaped into the breach.    As primary care physicians’ practices collapsed from documentation overburde...
Source: The Health Care Blog - July 26, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: The Business of Health Care Affordable Care Act COVID Jeff Goldsmith Physician-Owned hospitals Source Type: blogs

Featured Health IT Job: Director, Application Development and Integrations
We like to regularly feature a healthcare IT job that might be of interest to readers. Today, we’re featuring the Director, Application Development and Integrations position that was recently posted on Healthcare IT Central. This position was posted by New York eHealth Collaborative and is a hybrid position requiring one day in either the Manhattan, New York office or the Albany, New York office. Here’s a description of the position: New York eHealth Collaborative (NYeC) is a not-for-profit organization working in partnership with the New York State Department of Health to improve healthcare by collaborativel...
Source: EMR and HIPAA - July 26, 2023 Category: Information Technology Authors: Health IT Jobs Tags: Career and Jobs Healthcare IT Application Development and Integrations Director Jobs Health IT Jobs Healthcare IT Jobs Job Seekers New York eHealth Collaborative New York Health IT Jobs NYeC Source Type: blogs

Health Care, Disagree Better
BY KIM BELLARD On one of the Sunday morning news programs Governors Spence Cox (UT) and Jared Polis (CO) promoted the National Governors Association initiative Disagree Better. The initiative urges that we practice more civility in our increasingly civilized political discourse. It’s hard to argue the point (although one can question why NGA thinks two almost indistinguishable, middle-aged white men should be the faces of the effort), but I found myself thinking, hmm, we really need to do that in healthcare too.   No one seems happy with the U.S. healthcare system, and no one seems to have any real ideas about...
Source: The Health Care Blog - July 25, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Health insurance Healthcare Access Healthcare system Kim Bellard Source Type: blogs

Public Health Transparency Leads to Better Outcomes at San Bernardino County
Maps are important tools in infectious disease surveillance. They depict where cases are occurring and where treatment resources are needed. San Bernardino County uses geographic information system (GIS) technology to accurately track the prevalence of specific infectious diseases in their communities. That information is used to raise awareness and to marshal resources to limit the spread. Healthcare IT Today sat down with Diana Ibrahim, Public Health Program Manager and Umang Sharma, Statistical Analyst at the San Bernardino County Department of Public Health (SBCDPH), to learn more. GIS technology + Disease Surveillance...
Source: EMR and HIPAA - July 25, 2023 Category: Information Technology Authors: Colin Hung Tags: Analytics/Big Data Healthcare IT ArcGIS Diana Ibrahim Disease Surveillance esri GIS technology Healthcare Scene Featured infection surveillance Infectious Disease Tracking San Bernardino County Department of Public Health Umang Sharm Source Type: blogs

“The Problem is Not Lack of Information”: A Qualitative Study of Parents and School Nurses’ Perceptions of Barriers and Potential Solutions for Hpv Vaccination in Schools
Ève Dubé (Institut National De Santé Publique Du Québec), Chantal Sauvageau (Institut National De Santé Publique Du Québec), Maude Dionne (Institut National De Santé Publique Du Québec), Marilou Kiely (Institut National De Santé Publique Du Québec), “The Problem is Not... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - July 22, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

A Comparison of Electronic Health Records and the Oregon State Immunization Registry for Human Papilloma Virus Vaccine Delivery (2005-2022)
Sarah Bumatay (Oregon Rural Practice-based Research Network), Caitlin Dickinson (Oregon Rural Practice-based Research Network), Rex Larsen (Oregon Rural Practice-based Research Network), Isabel Stock (Oregon Rural Practice-based Research Network), A Comparison of Electronic Health Records and the Oregon State Immunization Registry... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - July 21, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Pulmonary Arterial Hypertension: Unraveling Its Impact On Heart And Lungs
Conclusion Navigating the complexities of Pulmonary Arterial Hypertension (PAH) might seem daunting. However, with the right knowledge and proactive approach, it’s possible to manage the condition and maintain a good quality of life. PAH, a unique type of high blood pressure affecting the arteries in the lungs, can put extra strain on the heart. Over time, this can lead to heart failure. The condition’s root cause may vary, from genetic factors to other health issues like heart defects, liver disease, or autoimmune diseases. Remember, sometimes the cause remains unknown, resulting in idiopathic pulmonary ...
Source: The EMT Spot - July 19, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer'...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs