HydrUStent ’s Biodegradable Stents Could Improve Patient Outcomes
Stents are widely used in patient care, but a major complication is infection and, for many types of stents, the need for eventual surgical removal. HydrUStent, a startup based at the University of Minho in Portugal, hopes to improve those limitations. HydrUStent’s product is a ureteral stent made from a patented material that is antibacterial, homogeneous, and biodegradable. It degrades by dissolution of the material in urine, which prevents the need for a second surgery for stent removal. “The dissolution profile is controlled and [depends] on the formulation used for stent production,” says CEO Alexandre Barros. B...
Source: Medgadget - June 26, 2018 Category: Medical Devices Authors: Cici Zhou Tags: Radiology Urology Source Type: blogs

5 things that can help you take a pass on kidney stones
If you’ve ever passed a kidney stone, you probably would not wish it on your worst enemy, and you’ll do anything to avoid it again. “Kidney stones are more common in men than in women, and in about half of people who have had one, kidney stones strike again within 10 to 15 years without preventive measures,” says Dr. Brian Eisner, co-director of the Kidney Stone Program at Harvard-affiliated Massachusetts General Hospital. Where do kidney stones come from? Kidney stones form develop when certain substances, such as calcium, oxalate, and uric acid, become concentrated enough to form crystals in your kidneys. The cry...
Source: Harvard Health Blog - March 8, 2018 Category: Consumer Health News Authors: Matthew Solan Tags: Health Kidney and urinary tract Source Type: blogs

Bladder exstrophy – CT
DISCUSSION BY DR MGK MURTHY& DR GA PRASADBladder exstrophy is a rare congenital birth defect  occurring about 3 in 100, 000 births with males to female ratio of 3:1& includes malformation of the bladder and urethra in which the bladder is turned inside out, flattened and exposed to  outside the body& bladder neck fails to form.The condition is caused by incomplete development of the infra- umbilical part of the anterior abdominal wall, associated with incomplete development of the anterior wall of the bladder owing to delayed rupture of the cloacal membrane. Persistence of the cloacal membrane pr...
Source: Sumer's Radiology Site - November 20, 2017 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Funtabulously Frivolous Friday Five 198
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 198. Question 1 The BBC ran an article on sexist adverts. Drug companies were not immune to providing sexist ads as well. What was the substance advertised below with the title “You can’t set her free. But you can help her feel less anxious.”? + R...
Source: Life in the Fast Lane - July 21, 2017 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five abbott's tube dario maestrini Frank Starling Curve legge del cuore Marchiafava-bignami syndrome mercury poisoning miller-abbott tube oxazepam sexist ads steinstrasse stone street Source Type: blogs

Ten Years In
My first day as an attending general surgeon in Cleveland, Ohio was August 7th, 2006. I saw one patient with a hernia in the office that day and then, around 430 pm, the call came in from the pediatric ER about a kid with abdominal pain. Some healthy 17 year old boy with obvious early appendicitis. I booked the case, tip-toed my way through the laparoscopic appendectomy uneventfully and went home feeling awful proud of myself. It was exactly how I envisioned a life as a general surgeon. I had been a confident 5th year resident. I hadn't done a fellowship. I had felt ready. I was read...
Source: Buckeye Surgeon - March 3, 2017 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs

Funtabulously Frivolous Friday Five 172
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 172. This week we have an animal based radiology quiz sourced from radiopaedia.org.  Question 1 What animal is winking at you? + Reveal the Funtabulous Answer expand(document.getElementById('ddet1221041592'));expand(document.getElementById('ddetlink1221041592')) An owl It is in reference to an absent pedicle. Differentials include, congenital absence, neurofibromatosis, radiation therapy, spinal metastases, int...
Source: Life in the Fast Lane - January 12, 2017 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five achalasia birds beak butterflies cobra head fractures owl pedicle Pulmonary Oedema radiopaedia.org rats tail stag stag antlers ureterocele winking owl sign Source Type: blogs

ConvertX Nephroureteral Stent System Avoids Extra Procedure
BrightWater Medical, a company based in Murrieta, California, won FDA clearance to introduce in the U.S. its ConvertX nephroureteral catheter and stent system for use in treating ureteral obstructions in patients that require perc nephrostomy tubes. The system is intended to be used by interventional radiologists and removes a separate minimally invasive procedure that is required with current treatment. Right now, a nephrostomy catheter is first placed to drain urine into a bag. The patient comes back a few days later to have the catheter removed and a stent placed. The ConvertX is designed to have the stent delivered dur...
Source: Medgadget - December 7, 2016 Category: Medical Equipment Authors: Editors Tags: Radiology Urology Source Type: blogs

Smoking Linked to One-Fourth of All US Cancer Deaths
For me personally, the noxious habit of smoking does not seem to exist any more. At home and when traveling to large cities in the U.S., I rarely see anyone smoking. And yet, here's an article that indicates that smoking is linked to one-fourth of all U.S. cancer deaths (see:One-fourth of US cancer deaths linked with 1 thing: smoking). Below is an excerpt from it:Cigarettes contribute to more than 1 in 4 cancer deaths in the U.S. The rate is highest among men in Southern states where smoking is more common and the rules against it are not as strict. The American Cancer Society study found the hi...
Source: Lab Soft News - November 15, 2016 Category: Laboratory Medicine Authors: Bruce Friedman Tags: General Healthcare Medical Consumerism Medical Education Medical Research Preventive Medicine Public Health Informatics Source Type: blogs

Research and Reviews in the Fastlane 140
In this study of 187 traumatic arrest patients, the survival rate was 3.2%. The authors found that if the patient had no cardiac motion AND no pericardial effusion, the mortality was 100%. This potentially identifies a group in which providers should not be subjected to the risks of thoracotomy. Recommended by Anand Swaminathan The Best of the Rest Emergency medicine Cheng YJ et al. The Role of Macrolide Antibiotics in Increasing Cardiovascular Risk. J Am Coll Cardiol. 2015. PMID 26564594 The harm is small – 1 in ~25,000 prescriptions – but this is another call to avoid unnecessary use of macrolide antibiotics w...
Source: Life in the Fast Lane - June 30, 2016 Category: Emergency Medicine Authors: Soren Rudolph Tags: Clinical Research Education Emergency Medicine Intensive Care LITFL Pre-hospital / Retrieval R&R in the FASTLANE Resuscitation Review Trauma critical care Source Type: blogs

Two MODYs walk into a bar...
Recently I had my follow up with the geneticist/Endocrinologist of last August's appointment. I absolutely adore her, because I have her personal email and every question I have is a promptly answered. Learning to live with MODY hasn't been all roses and sunshine, as I've developed a swelling of my left kidney (called hydronephrosis) which I've had an ultrasound and abdominal CT for and am scheduled for a renal perfusion scan in two weeks. It hasn't affected the overall function of said kidneys but it's there,like an albatross, needing attention. There are no kidney stones (#1 cause) and the geneticist feels like it's MODY...
Source: The D-Log Cabin - June 29, 2016 Category: Endocrinology Authors: HVS Source Type: blogs

FAQ: Understanding Kidney Stones (Part I)
What are kidney stones? Are small (at the beginning), hard mineral deposits that form in the kidney. Urine contains dissolved salts and minerals. If the urine has high levels of this deposits, you can form kidney stones. Stones can stay in the kidney, but eventually can travel down to the ureter, bladder and urethra. If the stone blocks the ureter, it also blocks the urinary flow and can cause excruciating pain. How common are kidney stones? The lifetime prevalence of having kidney stones is estimated at 1% to 15%. It varies according to race, age, gender and geographic location. Specifically, 114.3 per 100,000 people w...
Source: Unbounded Medicine - May 28, 2016 Category: Surgery Authors: Jon Mikel I ñarritu Tags: Fast Facts kidney lithiasis stones urology Source Type: blogs

FAQ: Understanding Kidney Stones (Part I)
What are kidney stones? Are small (at the beginning), hard mineral deposits that form in the kidney. Urine contains dissolved salts and minerales. If the urine has high levels of this deposits, you can form kidney stones. Stones can stay in the kidney, but eventually can travel down to the ureter, bladder and urethra. If the stone blocks the ureter, it also blocks the urinary flow and can cause excruciating pain. How common are kidney stones? The lifetime prevalence of having kidney stones is estimated at 1% to 15%. It varies according to race, age, gender and geographic location. Specifically, 114.3 per 100,000 people ...
Source: Unbounded Medicine - May 28, 2016 Category: Surgery Authors: Jon Mikel Iñarritu Tags: Fast Facts kidney lithiasis stones urology Source Type: blogs

“@deathunderglass is taking over the...
"@deathunderglass is taking over the @muttermuseum@instagram account this week to showcase some of the specimens in the museum collection related to forensic science! @deathunderglass is a collaboration between a forensic pathologist and forensic photographer that generates images of human tissue at high magnification. Whether know it or not, it's likely you have a few anatomic quirks you're not aware of – say, an accessory spleen or two, a double ureter, or an extra coronary ostium in your heart. One of the most common anatomic variants, affecting about 1 in 500 people, is the horseshoe kidney. Most people have two sep...
Source: Kidney Notes - May 10, 2016 Category: Urology & Nephrology Authors: Joshua Schwimmer Source Type: blogs

Don’t forget the power of over the counter remedies
I recently had an enormous kidney stone. Well OK, it seemed enormous to me. But in terms of kidney stones, it was reasonably large; 9 mm, in fact. Large enough that I had to have lithotripsy (the use of sound waves to break up the stone) performed by my friend and most excellent urologist, Dr. Robert McAlpine in Seneca, SC. As uncomfortable as the whole experience was (and it wasn’t my first rodeo either), I was reminded of something very important, which is that prescription drugs aren’t all they’re cracked up to be. In fact, the best pain relief I had from my kidney stone involved the little blue wonder pill (for w...
Source: Kevin, M.D. - Medical Weblog - May 3, 2016 Category: Journals (General) Authors: Tags: Meds Medications Primary care Source Type: blogs

In Defense of Small Data
By ANISH KOKA, MD I read with interest a recent editorial that opined on the poor evidence for screening in cancer trials. The evidence was judged poor because apparently no screening trial has demonstrated a clear reduction in all-cause mortality, only disease-specific mortality.  One example discussed in the analysis reviews the data for colon cancer screening and notes that, while there were a statistically significant lower number of deaths related to colon cancer in the screened group, the total mortality in the two groups was no different.  The authors posit that the study is either underpowered for total mortali...
Source: The Health Care Blog - March 9, 2016 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs