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Research and Reviews in the Fastlane 111
This study from Canada looked at the ED diagnosis of concussion in a convenience sample of 495 kids within 2 weeks of head injury and found that compared to the Zurich criteria, ED physicians underdiagnosed concussion. ED physicians diagnosed concussion in 40.4% of the patients, while the Zurich criteria for concussion were fulfilled by 89.5%. Concussion was more likely to be diagnosed in kids >10 years old, those playing collision sports, those with an injury >1 day prior, or 3+ symptoms. This criteria, in this case defined by SCAT3 (not validated in all head trauma/cumbersome in ED), may represent another area of o...
Source: Life in the Fast Lane - December 3, 2015 Category: Emergency Medicine Authors: Anand Swaminathan Tags: Airway Cardiology Emergency Medicine Infectious Disease Intensive Care Pediatrics Resuscitation Toxicology and Toxinology Trauma Urology critical care literature R&R in the FASTLANE recommendations research and reviews Source Type: blogs

Demonstrating an Integrated and Functional Kidney Organoid
Researchers have recently demonstrated in pigs the integration of an engineered kidney organoid, a few centimeters of kidney tissue grown from stem cells. The tissue functions as a kidney should, but it is far from full size, and does not bear all of the hallmarks of the real thing. However, enough of the normal suite of additional connections were also produced by the researchers involved to allow surgical integration of the organoid with the excretory system, and thus demonstrate generation of urine. This work well illustrates the nature of the challenges that lie ahead for the field of tissue engineering. It isn't enou...
Source: Fight Aging! - September 22, 2015 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Considering Klotho Delivery as a Means to Reduce Age-Related Stem Cell Decline
Today I'll point out an open access paper on the longevity-related gene klotho. Some researchers see therapies to adjust levels of the klotho protein produced from this genetic blueprint as a possible way to slow some of the effects of aging, particularly those connected to regeneration and stem cell activity. Work on this is slow-moving and painstaking, as for any similar approaches. Yet a fairly large section of the medical research community is now devoted to at least partial and temporary restoration of tissue maintenance by stem cells in the old. A good fraction of the frailty and failure of aging results not just fr...
Source: Fight Aging! - September 14, 2015 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Research and Reviews in the Fastlane 095
This article reveals the lack of knowledge about contrast reactions, but also reinforces the real risk of repeat reactions despite treatment. The authors found that despite premedication, patients with a history of a prior reaction were still at a significantly increased risk of a recurrent reaction. The bottom line is that premedication may not work. Be ready to treat these patients aggressively if symptoms occur. Recommended by:Daman Langguth Emergency Medicine, RespiratoryRaja AS, et al. Effects of Performance Feedback Reports on Adherence to Evidence-Based Guidelines in Use of CT for Evaluation of Pulmonary Embolism...
Source: Life in the Fast Lane - August 12, 2015 Category: Emergency Medicine Authors: Anand Swaminathan Tags: Education Emergency Medicine Intensive Care Respiratory Resuscitation Urology Wilderness Medicine critical care EBM literature R&R in the FASTLANE recommendations research and reviews Source Type: blogs

Case of hematuria- left ureteric calculus
Left ureteric/ ureteral calculus as a possible cause of hematuria in this patient:Left hydronephrosis and left hydroureterFor more such cases of ureteral stones see:http://www.ultrasound-images.com/ureteric-calculi/ (Source: cochinblogs)
Source: cochinblogs - March 27, 2015 Category: Radiology Source Type: blogs

Malpractice defense: Chiropractic adjustment allegedly caused Bell’s Palsy
I’m the former chairman of the board of Advanced Practice Strategies (APS) and I always find their malpractice defense cases to be fascinating. Illustrated Verdict by APS APS’ Demonstrative Evidence Group shares case examples from our archives to show how a visual strategy can support the defense effort. We hope that it is of value in your practice as you develop your defense strategies on behalf of health care providers. Please feel free to forward it to colleagues or clients.About Us APS is a leading provider of demonstrative evidence for the defense of medical malpractice claims. Our team of me...
Source: Health Business Blog - August 13, 2013 Category: Health Managers Authors: dewe67 Tags: Patients Physicians Source Type: blogs

Ureterolithotripsy
Basic equipment to perform semi-rigid (endoscopic) ureterolithotripsy for lithiasis of the lower third of the ureter. We use an ultra-thin uretero-renoscope and a lithotriptor (Swiss Lithoclast 2), the stone is fragmented and extracted from the ureter. Results are excellent. Soon, I’ll upload a video to show you how it is done. (Source: Unbounded Medicine)
Source: Unbounded Medicine - March 1, 2012 Category: Surgery Authors: Jon Mikel I ñarritu Tags: Med Gadgets Medical Images lithiasis Ureterolithotripsy urology Source Type: blogs

Minimal Reporting Guidelines for the Treatment of Cancer Patients
Minimal Reporting Guidelines for the Treatment of Cancer Patients As laboratory physicians, our contribution to patient care is knowledge: this is the starting point from which all informed therapeutic intervention proceeds. How that knowledge is obtained and communicated is the art and science of our profession. These minimal diagnostic guidelines are designed to be used as an aid, not a constraint, in that process. The guidelines are presented in a specific format out of necessity, but any format that effectively communicates the necessary information in a given patho...
Source: Oncopathology - September 5, 2011 Category: Cancer & Oncology Source Type: blogs