Two MODYs walk into a bar...

Recently I had my follow up with the geneticist/Endocrinologist of last August's appointment. I absolutely adore her, because I have her personal email and every question I have is a promptly answered. Learning to live with MODY hasn't been all roses and sunshine, as I've developed a swelling of my left kidney (called hydronephrosis) which I've had an ultrasound and abdominal CT for and am scheduled for a renal perfusion scan in two weeks. It hasn't affected the overall function of said kidneys but it's there,like an albatross, needing attention. There are no kidney stones (#1 cause) and the geneticist feels like it's MODY caused, such as stricture in the ureter causing back flow into the kidney. The renal perfusion scan will tell what's going on. In the meantime, I'm going to work very seriously on my a1c and try to get it down before the school stress starts up again. I'm going to prebolus, low carb it as much as I can, and try to eat more fruits and veggies to take the D out of the picture of kidney stressors. I'm also going to start taking some antioxidants, fish oil, and give glipizide another whirl. We talked a lot about the added risks to the kidneys with this condition (1 report of cancer,&just various kidney issues) and she recommended a yearly ultrasound with that yearly appointment. And we are talked about the genetics of it,&risks/dangers of it being passed down &the no way of knowing how the deletion will express itself in the next generation. It make...
Source: The D-Log Cabin - Category: Endocrinology Authors: Source Type: blogs

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This article attempts to aid clinicians in using diabetes devices in their clinical practice. It reviews device selection, initiation, and follow-up. It discusses work flow in an office and provides tips on billing. It stresses the need for patient choice, education, and on-going support through downloading and interpretation of data to optimize care. PMID: 31980122 [PubMed - in process]
Source: The Medical Clinics of North America - Category: General Medicine Authors: Tags: Endocrinol Metab Clin North Am Source Type: research
Authors: Fournier E Abstract Carpal tunnel syndrome (CTS) is too common a condition not to daily interact with the practitioner, if only because of its entanglement to other pathologies, causal or chance association. The typical symptomatology, with hand paresthesia and morning pain upon waking, is related to a median nerve injury in the confined space of the carpal tunnel, more often by local inflammation and tenosynovitis of the finger flexors (repetitive activity of the hands). SCC may be secondary to situations (pregnancy) or conditions (edema, hypothyroidism…), which exaggerate the ordinary pathophysiol...
Source: Revue de Medecine Interne - Category: Internal Medicine Tags: Rev Med Interne Source Type: research
Publication date: April 2020Source: Colloids and Surfaces B: Biointerfaces, Volume 188Author(s): Didem Cetin, Meltem Okan, Erhan Bat, Haluk KulahAbstractDetection of circulating tumor cells (CTCs) from the bloodstream holds great importance to diagnose cancer at early stages. However, CTCs being extremely rare in blood makes them difficult to reach. In this paper, we introduced different surface modification techniques for the enrichment and detection of MCF-7 in microfluidic biosensor applications using gold surface and EpCAM antibody. Mainly, two different mechanisms were employed to immobilize the antibodies; covalent b...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Publication date: Available online 25 January 2020Source: The Journal of Supercritical FluidsAuthor(s): P. Casademont, J. Sánchez-Oneto, A.P.J. Scandelai, L. Cardozo-Filho, J.R. PortelaAbstractThe Supercritical Water Gasification (SCWG) of black liquor (BL) to obtain hydrogen and dispose of organic waste simultaneously has been studied in a continuous reactor employing short residence times. The experiments were conducted at 600–700 °C, with times between 24.5–29.1 s, at 23 MPa and feedstock was diluted to different concentration levels (0.81–2.43 wt.%). Furthermore,...
Source: The Journal of Supercritical Fluids - Category: Chemistry Source Type: research
Publication date: Available online 25 January 2020Source: Journal of Solid State ChemistryAuthor(s): Meera Keskar, S.K. Sali, Geeta P. Shelke, Muhammed Shafeeq, S. KannanAbstractSynthesis, X-ray, chemical analysis and thermal properties of Nd doped (U, Th)O2 mixed oxides of the formula [(U0.3Th0.7)1-yNdy]O2+x; (Where y = 0–0.4) are reported in this work. The Nd doped mixed (U, Th)O2 oxides were synthesized using gel combustion method followed by heating the precursors at 1673 K in reduced atmosphere. Powder X-ray Diffraction (XRD) patterns of the mixed oxides showed retention of a single FCC phase up to 40 mo...
Source: Journal of Solid State Chemistry - Category: Chemistry Source Type: research
Publication date: 25 March 2020Source: Journal of Industrial and Engineering Chemistry, Volume 83Author(s): Xuan Thang Cao, Maheshkumar Prakash Patil, Quoc Thang Phan, Cuong M.Q. Le, Byung-Hyun Ahn, Gun-Do Kim, Kwon Taek LimAbstractThis paper reports a green and direct functionalization of poly(ethylene glycol)-graft-[furfuryl-graft-(poly(styrene-alt-maleic anhydride))] (PEG-PSMF) on the surface of single walled carbon nanotubes (SWCNTs) in aqueous media through Diels-Alder (DA) click reaction. Firstly, novel PEG grafted, furfuryl functionalized copolymers were prepared by RAFT polymerization followed by ring opening react...
Source: Journal of Industrial and Engineering Chemistry - Category: Chemistry Source Type: research
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Source: Journal of Industrial and Engineering Chemistry - Category: Chemistry Source Type: research
In this study, CaCu3Ti4O12 (CCTO) modified polyethersulfone (PES) HF membranes were prepared via dry-wet phase inversion by adding different concentration of CCTO particles (0–4 wt.%) in the dope solution. The synthesized PES/CCTO composites were characterized by viscosity measurement, scanning electron microscope, X-ray diffraction, contact angle, pore size, and pore size distribution. The flux and the photocatalytic activity of CCTO entrapped PES membranes were subsequently evaluated by crossflow ultrafiltration and the photodegradation of Rhodamine B (RhB) under UV irradiation, respectively. The pure water ...
Source: Journal of Industrial and Engineering Chemistry - Category: Chemistry Source Type: research
Publication date: 25 March 2020Source: Journal of Industrial and Engineering Chemistry, Volume 83Author(s): Liangbo Zhang, Siyuan ShenAbstractIn this work, a composite material of mesoporous carbon loaded nano zero valent iron (nZVI/MC) was prepared and used as an activator of persulfate (PS) to degrade sulfamethazine (SMZ). Scanning electron microscopy (SEM) images showed nano zero valent iron (nZVI) was dispersed on the surface or in the mesopores of mesoporous carbon (MC) without aggregation. nZVI/MC has less surface area (175.63 m2 g−1) than MC (240.83 m2 g−1). The adsorption efficiency ...
Source: Journal of Industrial and Engineering Chemistry - Category: Chemistry Source Type: research
Publication date: Available online 25 January 2020Source: Colloids and Surfaces A: Physicochemical and Engineering AspectsAuthor(s): Yan Li, Shuai Wang, Fang Xiang Song, Li Zhang, Wei Yang, Hong Xia Wang, Qian Lin ChenAbstractMesoporous silica nanoparticles with folic acid (MSN-COOH-Tet-HBP-FA) are able to mediate targeting and have a pH stimulation response character, and therefore have been successfully synthesized as vectors for antitumor drug delivery. The model drug is tetrandrine (Tet). The chemical structure and properties of these NPs were characterized through systematic characterization analyses. Their drug loadi...
Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
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