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Mystery illness among U.S. diplomats did not cause permanent brain damage
For several years, dozens of U.S. diplomats and intelligence agents have fallen ill with a perplexing array of symptoms that some politicians, intelligence analysts, and physicians have speculated may have been triggered by a so-called directed-energy weapon. Whatever caused these anomalous health incidents (AHIs), as the cases have been labeled by the U.S. government, it did not leave lasting brain damage, two new studies suggest. “We hope these results will alleviate concerns about AHIs being associated with severe neurodegenerative changes in the brain,” says Carlo Pierpaoli, chief of the Laboratory on Quantit...
Source: Science of Aging Knowledge Environment - March 18, 2024 Category: Geriatrics Source Type: research

Gesture profiles distinguish primary progressive aphasia variants: a preliminary study
. (Source: Aphasiology)
Source: Aphasiology - March 12, 2024 Category: Speech-Language Pathology Authors: Haley C. DresangRand WilliamsonHana KimArgye E. HillisLaurel J. Buxbauma Jefferson Health, Moss Rehabilitation Research Institute, Elkins Park, PA, USAb Department of Neurology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, US Source Type: research

This tiny swimming robot can think for itself
MINNEAPOLIS— Tiny robots that swim through our blood to deliver drugs or hunt down pathogens have been a staple of science fiction for decades. Although still distant, that vision is a step closer to reality now that electrical engineers have unveiled swimming microrobots smaller than grains of sand with enough computing power to perform a simple task on their own—rather than being constantly guided by external signals. “It’s awesome,” says Daniel Goldman, a physicist at the Georgia Institute of Technology who specializes in larger robots that mimic animals. He was not involved in the work, which was ...
Source: Science of Aging Knowledge Environment - March 7, 2024 Category: Geriatrics Source Type: research

News at a glance: Methane-hunting satellite, Elsevier ’s earnings, and protecting Kinsey
ENVIRONMENT White House wants to weigh ecosystem benefits President Joe Biden’s administration published guidance last week for U.S. federal agencies to weigh benefits to human health and welfare provided by natural resources when considering whether to undertake or approve actions that could harm them. These “ecosystem benefits” include clean water and air and intangible perks such as spiritual connections to nature. Until now, federal rules have required agencies to analyze costs and benefits when building roads or issuing permits for logging or mining, for example, but did not explicitly men...
Source: Science of Aging Knowledge Environment - March 7, 2024 Category: Geriatrics Source Type: research

Design and rationale of the Post-Intensive Care Syndrome - paediatrics (PICS-p) Longitudinal Cohort Study
This study has received ethical approval from the University of Pennsylvania Institutional Review Board (protocol #843844). Our overall objective is to characterise the ongoing impact of paediatric critical illness to guide development of interventions that optimise outcomes among children surviving critical illness and their families. Findings will be presented at key disciplinary meetings and in peer-reviewed publications at fixed data points. Published manuscripts will be added to our public study website to ensure findings are available to families, clinicians and researchers. Trials registration number NCT04967365. (Source: BMJ Open)
Source: BMJ Open - February 24, 2024 Category: General Medicine Authors: Curley, M. A. Q., Watson, R. S., Killien, E. Y., Kalvas, L. B., Perry-Eaddy, M. A., Cassidy, A. M., Miller, E. B., Talukder, M., Manning, J. C., Pinto, N. P., Rennick, J. E., Colville, G., Asaro, L. A., Wypij, D. Tags: Open access, Intensive care Source Type: research

Alabama IVF ruling may halt uterine transplant program
The Supreme Court of Alabama’s ruling last week declaring frozen embryos at fertility clinics to be people has upended patient care there. The state’s two leading private in vitro fertilization providers as well as the University of Alabama at Birmingham (UAB) paused all IVF procedures earlier this week while officials sort through the legal risks of continuing to create and store embryos and impregnate patients. But the impacts extend beyond would-be parents, to research. A uterus transplant program in which women conceive by IVF—one of only four in the country—is located at UAB, and its leader is also co–...
Source: Science of Aging Knowledge Environment - February 23, 2024 Category: Geriatrics Source Type: research

One in Five Who Attempt Suicide Have No Prior Mental Illness
Nearly one in five people who attempt suicide either have no history of prior mental illness or do not meet the criteria for a diagnosis of mental illness at the time of the attempt, astudy inJAMA Psychiatry suggests.“This finding challenges clinical notions of who is at risk for suicidal behavior and raises questions about the safety of limiting suicide risk screening to psychiatric populations,” wrote Past APA President Maria A. Oquendo, M.D., Ph.D., of the University of Pennsylvania and colleagues.The researchers analyzed data from 1,948 adults (66.8% female) aged 20 to 65 years with a history of suicide attempts wh...
Source: Psychiatr News - February 23, 2024 Category: Psychiatry Tags: JAMA Psychiatry Maria Oquendo mental illness risk screening suicide attempt survey Source Type: research

Predictors of Identity Crime Victimization of Adolescent Youth in Foster Care
. (Source: Victims and Offenders)
Source: Victims and Offenders - February 23, 2024 Category: Criminology Authors: John R. GyourkoGreg Ridgewaya School of Social Policy and Practice, University of Pennsylvania, Philadelphia, Pennsylvania, USAb Field Center for Children ’s Policy, Practice & Research, University of Pennsylvania, Philadelphia, Pennsylvania, USAc Depa Source Type: research

The 2024 ASM Awards and Prize Program —recognizing excellence in the microbiological sciences
Journal of Clinical Microbiology, Ahead of Print. (Source: Journal of Clinical Microbiology)
Source: Journal of Clinical Microbiology - February 23, 2024 Category: Microbiology Authors: Irving NachamkinN. Esther Babady1Member and Past Chair, Subcommittee on Awards, American Academy of Microbiology, Washington, DC, USA2Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, P Source Type: research

Olfaction and Quality of Life in Patients with Eosinophilic CRS Undergoing Endoscopic Sinus Surgery
Conclusion Surgery effectively controlled eCRS in patients who adhered to high-volume budesonide nasal irrigation postoperatively. There were significant improvements in quality of life and olfaction, which persisted at least up to one year postoperatively. [...] Thieme Revinter Publicações Ltda. Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, BrazilArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: International Archives of Otorhinolaryngology)
Source: International Archives of Otorhinolaryngology - February 16, 2024 Category: ENT & OMF Authors: Tepedino, Miguel Soares Voegels, Richard Louis Pezato, Rog ério Thamboo, Andrew Kosug, Eduardo Macoto Ferr ão, Ana Clara Miotello Neves, Ra íssa de Figueiredo Castilla, Val éria Maria Barcia Greg ório, Luis Carlos Tags: Original Research Source Type: research

Passion is not misconduct | Science
University of Pennsylvania climate scientist Michael Mann was awarded more than $1 million in a lawsuit against bloggers who accused him of scientific misconduct in inflammatory terms, likening his treatment of data to what a noted child molester did to ... (Source: Science: Current Issue)
Source: Science: Current Issue - February 13, 2024 Category: Science Source Type: research

Jury rules for climate scientist Michael Mann in long-running defamation case
A jury found today that Michael Mann, a prominent climate scientist, was defamed by the writers of two blog posts 12 years ago that compared his work on global warming to child molestation. In ruling for Mann, the six-person jury in the Superior Court of the District of Columbia awarded Mann just $2 in actual damages due to the defamation, but then levied a $1 million fine against one of the defendants, Mark Steyn, a conservative author and broadcaster, for punitive damages; Rand Simberg, the other defendant, faces $1000 in punitive damages. The ruling is a victory for climate researchers who have been frequent...
Source: Science of Aging Knowledge Environment - February 8, 2024 Category: Geriatrics Source Type: research

Recovery of the spatially-variant deformations in dual-panel PET reconstructions using deep-learning
Phys Med Biol. 2024 Feb 8. doi: 10.1088/1361-6560/ad278e. Online ahead of print.ABSTRACTDual panel PET systems, such as Breast-PET (B-PET) scanner, exhibit strong asymmetric and anisotropic spatially-variant deformations in the reconstructed images due to the limited-angle data and strong depth of interaction effects for the oblique LORs inherent in such systems.
In our previous work, we studied TOF effects and image-based spatially-variant PSF resolution models within dual-panel PET reconstruction to reduce these deformations.
The application of PSF based models led to better and more uniform quantificatio...
Source: Physics in Medicine and Biology - February 8, 2024 Category: Physics Authors: Juhi Raj Ma ël Baptiste Millardet Srilalan Krishnamoorthy Joel S Karp Suleman Surti Samuel Matej Source Type: research

Omega-3 Supplementation May Reduce Symptoms of Schizotypal Personality Disorder in Children
Community-dwelling children with schizotypal personality disorder may benefit from dietary supplementation with omega-3 fatty acids, according to areport inSchizophrenia Bulletin. Schizotypal personality disorder (or “schizotypy”) is marked by symptoms of aggression and interpersonal and cognitive problems that can be precursors to schizophrenia.“Poor nutrition has long been associated with schizophrenia-spectrum disorders, including schizoid personality and schizotypal personality,” wrote Adrian Raine, D. Phil., of the University of Pennsylvania and colleagues. One of the researchers’ previous studies found that...
Source: Psychiatr News - February 7, 2024 Category: Psychiatry Tags: Adrian Raine CBT conduct disorder omega 3 fatty acids oppositional defiant disorder schizotypal personality disorder schizotypy SPQ-C19 University of Pennsylvania Source Type: research

Artificial Intelligence and Technology Collaboratories: Innovating aging research and Alzheimer's care
The objective is to apply these innovations effectively in real-world scenarios, including in rural settings. In addition, the AITC focuses on developing best practices for AI application in the care of older adults, facilitating pilot studies, and addressing ethical concerns related to technology development for older adults with cognitive impairment, with the ultimate aim of improving the lives of older adults and their caregivers. HIGHLIGHTS: Addressing the complex needs of older adults with Alzheimer's disease (AD) requires a comprehensive approach, integrating medical and social support. Current gaps in training, tech...
Source: The Journal of Alzheimers Association - February 7, 2024 Category: Psychiatry Authors: Peter Abadir Esther Oh Rama Chellappa Niteesh Choudhry George Demiris Deepak Ganesan Jason Karlawish Benjamin Marlin Rose M Li Najim Dehak Alicia Arbaje Mathias Unberath Thomas Cudjoe Christopher Chute Jason H Moore Phillip Phan Quincy Samus Nancy L Schoe Source Type: research