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Immunogenicity Response of Mus musculus var. Balb/C after Immunization using Flagellin Salmonella typhi Serovar Semarang
Conclusion: The results indicated that the flagellin protein of S. typhi serovar Semarang induces adaptive immune responses and produces specific antibodies against flagellin. The immunogenic properties of the flagellin protein of S. typhi serovar Semarang potentially developed as a specific diagnostic marker. Further research may also focus on a beneficial feature of flagellin as a vaccine candidate.PMID:36978276 | DOI:10.3923/pjbs.2022.1085.1093 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - March 29, 2023 Category: Biomedical Science Authors: Sri Darmawati I Agus Adi Gunawan Nastiti Wijayanti Muchamad Dafip Source Type: research

Genes, Vol. 14, Pages 823: Genomic Characterization and Genetic Profiles of Salmonella Gallinarum Strains Isolated from Layers with Fowl Typhoid in Colombia
This study presents, for the first time, the genomic content of Colombian SG strains and a profile of the genetic elements frequently found in SG, which can be further studied to clarify the pathogenicity and evolutionary characteristics of this serotype. (Source: Genes)
Source: Genes - March 29, 2023 Category: Genetics & Stem Cells Authors: Ruy D. Chac ón Manuel Ram írez Carmen L. Rodr íguez-Cueva Christian S ánchez Wilma Ursula Quispe-Rojas Claudete S. Astolfi-Ferreira Antonio J. Piantino Ferreira Tags: Article Source Type: research

Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains the efficacy of immune responses
DiscussionTherefore, Vi-specific IgM or IgG are independently capable of protecting from infection and any superior protection from vaccination with TCV in adults may relate to responses being able to persist better rather than from differences in the antibody isotypes induced. These findings suggest that enhancing our understanding of how responses to vaccines are maintained may inform on how to maximize protection afforded by conjugate vaccines against encapsulated pathogens such as S. Typhi. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - March 23, 2023 Category: Allergy & Immunology Source Type: research