Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals
Conditions: Acute Hydrocarbon Toxicity Interventions: Diagnostic Test: serum procalcitonin; Diagnostic Test: C-reactive protein Sponsors: Sohag University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 30, 2023 Category: Research Source Type: clinical trials
Evaluating newly approved drugs in combination regimens for multidrug-resistant tuberculosis with fluoroquinolone resistance (endTB-Q): study protocol for a multi-country randomized controlled trial
DiscussionThis internally controlled study of shortened treatment for pre-XDR TB will provide urgently needed data and evidence for clinical and policy decision-making around the treatment of pre-XDR TB with a four-drug, all-oral, shortened regimen.Trial registrationClinicalTrials.Gov NCT03896685. Registered on 1 April 2018; the record was last updated for study protocol version 4.3 on 17 March 2023. (Source: Trials)
Source: Trials - November 30, 2023 Category: Research Source Type: clinical trials
Effects of Glucocortioids in Human Skeletal Muscle, Adipose Tissue and Skin
Conditions: Glucocorticoids Toxicity; Iatrogenic Effect Interventions: Other: Prednisolone; Other: Placebo Sponsors: University of Aarhus Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials
A flexible dose-response modeling framework based on continuous toxicity outcomes in phase I cancer clinical trials
ConclusionsPhase I cancer clinical trials, designed within a fully Bayesian framework with the utilization of continuous toxicity outcomes, offer an alternative approach to finding an optimal dose, providing unique benefits compared to trials designed based on binary toxicity outcomes. (Source: Trials)
Source: Trials - November 21, 2023 Category: Research Source Type: clinical trials
Ameliorating Contrast Induced Nephropathy After Coronary Angiography
Conditions: Coronary Artery Disease; Nephropathy; Toxic, Drugs Interventions: Drug: Atorvastatin 80mg; Drug: N-acetyl cysteine; Other: Normal Saline Sponsors: Ain Shams University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 18, 2023 Category: Research Source Type: clinical trials
Nasopharyngeal Carcinoma Treated With Reduced Volume Intensity Modulated Radiation Therapy:10-Year Outcome and Late Toxicity, Quality of Life
Conditions: Nasopharyngeal Carcinoma Sponsors: Fujian Cancer Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 17, 2023 Category: Research Source Type: clinical trials
Adjunctive Clindamycin Versus Linezolid for β-lactam Treated Patients With Invasive Group A Streptococcal Infections
Conditions: Streptococcal Sepsis; Invasive Group A Beta-Haemolytic Streptococcal Disease; Necrotizing Soft Tissue Infection; Infection, Bloodstream; Infection, Bacterial; Streptococcal Toxic Shock Syndrome Interventions: Drug: Linezolid; Drug: Clindamycin Sponsors: National Institutes of Health Clinical Center (CC); Emory University Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 10, 2023 Category: Research Source Type: clinical trials
Prodromes of Menstrual Staphylococcal Toxic Shock
Conditions: Toxic Shock Syndrome Staphylococcal Interventions: Other: Identification of symptoms of menstrual staphylococcal toxic shock in last three menstrual period; Other: Identification of symptoms of menstrual in control patient in the last three menstrual period Sponsors: Hospices Civils de Lyon Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 9, 2023 Category: Research Source Type: clinical trials
Pattern of Acute Antipsychotic Drug- Toxicity in Children
Conditions: Antipsychotic Drug- Toxicity Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 9, 2023 Category: Research Source Type: clinical trials
Evaluation of High Dose Methotrexate Toxicity
Conditions: Methotrexate Toxicity Interventions: Diagnostic Test: blood methotrexate level and Cystatin C level Sponsors: Sohag University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 8, 2023 Category: Research Source Type: clinical trials
Evaluation of the Efficacy and Safety of Methylprednisolone Combined With the JAK Inhibitors in the Treatment of Toxic Epidermal Necrolysis
Conditions: Toxic Epidermal Necrolysis Interventions: Drug: Abrocitinib Sponsors: Peng Zhang Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 7, 2023 Category: Research Source Type: clinical trials
Crisaborole Ointment for Skin Toxicity Induced by Cetuximab
Conditions: Metastatic Colorectal Cancer; Cetuximab; Skin Toxicity Interventions: Drug: Crisaborole Ointment; Drug: Cetuximab Sponsors: Sun Yat-sen University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 6, 2023 Category: Research Source Type: clinical trials
A Study to Develop Molecular Integrated Predictive Models of Breast Radio-toxicity (Precise-RTox)
Conditions: Breast Cancer Sponsors: Centro di Riferimento Oncologico - Aviano Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 2, 2023 Category: Research Source Type: clinical trials
Paraoxonase-1 Pseudo Cholinesterase Organophosphate Toxicity Enzyme in Prediction the Severity and Outcome of Acute Organophosphate Poisoning and Its Correlation With Pseudo Cholinesterase Enzyme Level.
Conditions: Organophosphate Poisoning Interventions: Diagnostic Test: Serum Pararoxonase -1 level; Diagnostic Test: Diagnostic Test: Serum pseudocholinesterase enzyme level Sponsors: Sohag University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 31, 2023 Category: Research Source Type: clinical trials
Toxicity and Efficacy Evaluation of Topical Minoxidil in Acne Vulgaris
Conditions: Acne Vulgaris Interventions: Drug: topical minoxidil in Acne Vulgaris Sponsors: Chang Gung Memorial Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 30, 2023 Category: Research Source Type: clinical trials
