Evaluation of Radiobiological Effects in Skin Toxicities Head and Neck Cancer Patients With PBS Proton Therapy
Conditions: Head and Neck Cancer; Head and Neck Squamous Cell Carcinoma; Head and Neck Carcinoma Interventions: Radiation: Spot Delete Sponsors: Thompson Cancer Survival Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 27, 2023 Category: Research Source Type: clinical trials
The STOP-MED CTRCD Trial
Conditions: Heart Failure; Cardiotoxicity; Cardiac Toxicity; Antineoplastics Toxicity; Cancer Interventions: Other: Stopping Heart Failure Medication(s) Sponsors: University Health Network, Toronto; Unity Health Toronto; Hamilton Health Sciences Corporation; St. Boniface Hospital; University of Alberta; University of Ottawa Heart Institute, Canada; University College London Hospitals; Alberta Health Services, Calgary; Brigham and Women ' s Hospital; Baker Heart and Diabetes Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 27, 2023 Category: Research Source Type: clinical trials
Preoperative Administration of Lugols Solution in Toxic Thyroid Diseases (TD): A Prospective Study
Conditions: Toxic; Thyroid Interventions: Dietary Supplement: Lugol ' s iodine solution 5% Sponsors: Aristotle University Of Thessaloniki Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 20, 2023 Category: Research Source Type: clinical trials
A Study to Evaluate the Efficacy and Toxicities of PLX038, in Patients With Locally Advanced or Metastatic Triple-negative Breast Cancer
Conditions: Breast; Cancer Interventions: Drug: PLX038 Sponsors: Institut Curie; ProLynx LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 8, 2023 Category: Research Source Type: clinical trials
Ventilation Using Radiographic Examination: Functional Lung Imaging Techniques for the Reduction of Toxicity in Functional Avoidance Radiation Therapy
Conditions: Lung Neoplasm Sponsors: University of Sydney; National Health and Medical Research Council, Australia; Northern Sydney and Central Coast Area Health Service Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 7, 2023 Category: Research Source Type: clinical trials
IMRT Versus 3DCRT for Locally Advanced Rectal Cancer, Prospective Phase II Study.
Conditions: Rectal Cancer; Radiotherapy; Toxicity Due to Radiotherapy Interventions: Radiation: Intensive Modulated Radiation Therapy; Radiation: 3-Dimension Conformal Radiation Therapy Sponsors: Rabin Medical Center Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 7, 2023 Category: Research Source Type: clinical trials
PD-1 Inhibitor Based Induction Chemotherapy Followed by De-escalation Protocols in OPSCC
Conditions: Oropharyngeal Cancer Interventions: Procedure: Toxicities reduced treatment; Procedure: Conventional treatment Sponsors: Fudan University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials
Effect of Salovum ™ and SPC-Flakes™ on Abemaciclib-induced Gastrointestinal Toxicity in Early Breast Cancer
Conditions: Early-stage Breast Cancer; Diarrhea; Adverse Drug Event Interventions: Drug: SPC-flakes; Drug: Salovum; Drug: Placebo Sponsors: Henrik Lindman Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 30, 2023 Category: Research Source Type: clinical trials
Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals
Conditions: Acute Hydrocarbon Toxicity Interventions: Diagnostic Test: serum procalcitonin; Diagnostic Test: C-reactive protein Sponsors: Sohag University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 30, 2023 Category: Research Source Type: clinical trials
Evaluating newly approved drugs in combination regimens for multidrug-resistant tuberculosis with fluoroquinolone resistance (endTB-Q): study protocol for a multi-country randomized controlled trial
DiscussionThis internally controlled study of shortened treatment for pre-XDR TB will provide urgently needed data and evidence for clinical and policy decision-making around the treatment of pre-XDR TB with a four-drug, all-oral, shortened regimen.Trial registrationClinicalTrials.Gov NCT03896685. Registered on 1 April 2018; the record was last updated for study protocol version 4.3 on 17 March 2023. (Source: Trials)
Source: Trials - November 30, 2023 Category: Research Source Type: clinical trials
Effects of Glucocortioids in Human Skeletal Muscle, Adipose Tissue and Skin
Conditions: Glucocorticoids Toxicity; Iatrogenic Effect Interventions: Other: Prednisolone; Other: Placebo Sponsors: University of Aarhus Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials
A flexible dose-response modeling framework based on continuous toxicity outcomes in phase I cancer clinical trials
ConclusionsPhase I cancer clinical trials, designed within a fully Bayesian framework with the utilization of continuous toxicity outcomes, offer an alternative approach to finding an optimal dose, providing unique benefits compared to trials designed based on binary toxicity outcomes. (Source: Trials)
Source: Trials - November 21, 2023 Category: Research Source Type: clinical trials
Ameliorating Contrast Induced Nephropathy After Coronary Angiography
Conditions: Coronary Artery Disease; Nephropathy; Toxic, Drugs Interventions: Drug: Atorvastatin 80mg; Drug: N-acetyl cysteine; Other: Normal Saline Sponsors: Ain Shams University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 18, 2023 Category: Research Source Type: clinical trials
Nasopharyngeal Carcinoma Treated With Reduced Volume Intensity Modulated Radiation Therapy:10-Year Outcome and Late Toxicity, Quality of Life
Conditions: Nasopharyngeal Carcinoma Sponsors: Fujian Cancer Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 17, 2023 Category: Research Source Type: clinical trials
Adjunctive Clindamycin Versus Linezolid for β-lactam Treated Patients With Invasive Group A Streptococcal Infections
Conditions: Streptococcal Sepsis; Invasive Group A Beta-Haemolytic Streptococcal Disease; Necrotizing Soft Tissue Infection; Infection, Bloodstream; Infection, Bacterial; Streptococcal Toxic Shock Syndrome Interventions: Drug: Linezolid; Drug: Clindamycin Sponsors: National Institutes of Health Clinical Center (CC); Emory University Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 10, 2023 Category: Research Source Type: clinical trials
