Evaluation of the Effect of N-acetylcysteine in Preventing Cisplatin-Induced Toxicities in Cancer Patients
Conditions: Cisplatin Adverse Reaction; Cisplatin Nephrotoxicity; Cisplatin Induced Peripheral Neuropathy; Cancer Patients; Cisplatin Ototoxicity Interventions: Drug: N acetyl cysteine Sponsors: Ain Shams University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
A Phase I/II Trial to Assess the Efficacy and Toxicity of ASTX727 (Oral Decitabine/Cedazuridine) for the Treatment of Hematological Neoplasms After Allogeneic Stem Cell Transplantation
Conditions: Allogeneic Stem Cell Transplantation Interventions: Drug: ASTX727; Drug: Donor Lymphocyte Infusion Sponsors: M.D. Anderson Cancer Center; Astex Pharmaceuticals, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures
Conditions: Tobacco Use; Cigarette Smoking; Nicotine Dependence Interventions: Other: Cigarettes Sponsors: Masonic Cancer Center, University of Minnesota; National Institutes of Health (NIH) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2024 Category: Research Source Type: clinical trials
Brentuximab Vedotin Combined With Bendamustine Supercharge, a Low-toxicity and Efficient Salvage Regimen for Primary Refractory or First-relapsed Classic Hodgkin Lymphoma: Long-term Results of a Retrospective Monocenter Study.
Conditions: Hodgkin Lymphoma Interventions: Other: observational Sponsors: Federico II University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2024 Category: Research Source Type: clinical trials
Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma
Conditions: Esophageal Squamous Cell Carcinoma; Efficacy; Toxicity Interventions: Drug: Induction Immunotherapy-Toripalimab; Drug: Induction Chemotherapy-Albumin-paclitaxel combined with cisplatin; Radiation: Radiotherapy; Drug: Apatinib; Drug: Capecitabine Sponsors: Sun Yat-sen University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
Evaluation of Impedance Cardiography for Assessing Hemodynamic Shifts in Patients With LA-NSCLC During Treatment.
Conditions: Non-small Cell Lung Cancer; Cardiac Toxicity Interventions: Other: Impedance cardiography Sponsors: Sun Yat-sen University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials
Efficacy of Structured SOcial COnsultation and Support in Reducing the FINancial Burden of Radiotherapy
Conditions: Financial Toxicity Interventions: Other: Questionnaire Sponsors: University Medical Center Goettingen Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials
Effect of Sarcopenia on the Occurrence of Toxicity Related to Anti-cancer Treatments
Conditions: Sarcopenia; Oncology; Physical Inactivity; Toxicity Due to Chemotherapy Interventions: Diagnostic Test: Sarcopenia diagnostic test Sponsors: Centre Hospitalier Metropole Savoie; Universit é Savoie Mont Blanc Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials
Effects of Exercise Training in Survivors of Lymphoma
Conditions: Lymphoma; Physical Exercise; Cardiotoxicity; Cardiovascular Diseases; Chemotherapeutic Toxicity Interventions: Behavioral: Aerobic Exercise; Behavioral: Combined Aerobic and Resistance Exercise Sponsors: Norwegian School of Sport Sciences; Uppsala University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2024 Category: Research Source Type: clinical trials
Non Interventional Study on Iron Toxicity After First Allo-transplant in MDS/CMML
Conditions: MDS; CMML Sponsors: European Society for Blood and Marrow Transplantation; Novartis Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2024 Category: Research Source Type: clinical trials
SAMe in Prevention of Oxaliplatin-associated Liver Injury
Conditions: Colorectal Cancer; Liver Metastases; Liver Metastasis Colon Cancer; Liver Injury; Sinusoidal Obstruction Syndrome; 5-Fluorouracil Toxicity; Liver Toxicity, Chemically-Induced Interventions: Radiation: Standard of care oxaliplatin-based chemotherapy; Dietary Supplement: S-adenosylmethionine (SAMe) supplement; Procedure: Surgery Sponsors: Cedars-Sinai Medical Center; Jarrow Formulas Inc Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials
Cancer Precision-Prevention trial of Metformin in adults with Li Fraumeni syndrome (MILI) undergoing yearly MRI surveillance: a randomised controlled trial protocol
DiscussionAlongside a parallel MILI study being conducted by collaborators at the National Cancer Institute (NCI), MILI is the first prevention trial to be conducted in this high-risk group. The MILI study provides a unique opportunity to evaluate the efficacy of metformin as a chemopreventive alongside exploring its m echanism of anticancer action and the biological process of mutated P53-driven tumourigenesis.Trial registrationISRCTN16699730. Registered on 28 November 2022. URL:https://www.isrctn.com/ EudraCT/CTIS number 2022-000165-41. (Source: Trials)
Source: Trials - February 3, 2024 Category: Research Source Type: clinical trials
Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab
Conditions: Urologic Neoplasms; Urogenital Neoplasms; Neoplasms by Site; Neoplasms; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Urinary Bladder Diseases; Male Urogenital Diseases; Urinary Bladder Neoplasm; Antineoplastics Toxicity Interventions: Drug: Nivolumab; Drug: Relatlimab Sponsors: The Netherlands Cancer Institute; Bristol-Myers Squibb Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 2, 2024 Category: Research Source Type: clinical trials
Aminoglycoside Administration in Septic Patients
Conditions: Sepsis; Septic Shock; Aminoglycoside Toxicity; Renal Replacement Therapy Interventions: Procedure: Continuous Renal Replacement Therapy Sponsors: University of Thessaly Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 26, 2024 Category: Research Source Type: clinical trials
The Exploratory Study About the Effect of Using Double Filtration Plasmapheresis (DFPP) Removing Inflammatory Cytokines, Lipids and Toxic Metal Ions in Peripheral Blood in Adults
Conditions: Sub-healthy; Hyperlipidemia; Toxic Metal Ions Accumulation Interventions: Device: DFPP; Device: DFPP; Device: DFPP Sponsors: Shanghai Cell Therapy Group Co.,Ltd; Shanghai Mengchao Cancer Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2024 Category: Research Source Type: clinical trials
