Expressions of ion co-transporter genes in salicylate-induced tinnitus and treatment effects of spirulina
Although the activity of tinnitus-related ion co-transporter are known, their mRNA expressions has seldom been reported. We aimed to investigate the mRNA expressions of tinnitus-related ion co-transporter gene... (Source: BMC Neurology)
Source: BMC Neurology - September 2, 2016 Category: Neurology Authors: Juen-Haur Hwang and Yin-Ching Chan Source Type: research

Evolution of treatment and a detailed analysis of occlusion, recurrence, and clinical outcomes in an endovascular library of 260 dural arteriovenous fistulas.
CONCLUSIONS Overall, in the Onyx era, the rate of initial angiographic occlusion was approximately 80%, as was the rate of meaningful clinical improvement in tinnitus and/or ocular symptoms after initial endovascular treatment of cranial dAVFs. PMID: 27588586 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - September 1, 2016 Category: Neurosurgery Authors: Gross BA, Albuquerque FC, Moon K, McDougall CG Tags: J Neurosurg Source Type: research

[Treatment and auditory rehabilitation of intralabyrinthine schwannoma by means of cochlear implants - German Version].
This study aimed to assess the results of auditory rehabilitation after treatment with CI in a series of cases. MATERIALS AND METHODS: The demographic findings, symptoms, and results of surgical therapy in 8 patients were evaluated in a retrospective analysis. RESULTS: Prior to surgery, all patients presented with profound hearing loss and tinnitus. Episodic dizziness was reported by 3 patients. Among the patients, 4 had an intracochlear and 3 an intravestibular schwannoma, and a transmodiolar schwannoma was found in 1 patient. A total of 6 patients underwent treatm...
Source: HNO - September 1, 2016 Category: ENT & OMF Tags: HNO Source Type: research

Tinnitus and Its Relation to Emotion, Exercise
No abstract available (Source: The Hearing Journal)
Source: The Hearing Journal - September 1, 2016 Category: Audiology Tags: Tinnitus Research Source Type: research

Survey on the Effectiveness of Dietary Supplements to Treat Tinnitus
Conclusions The use of dietary supplements to treat tinnitus is common, particularly withGinkgo biloba, lipoflavonoids, magnesium, melatonin, vitamin B12, and zinc. It is likely that some supplements will help with sleep for some patients. However, they are generally not effective, and many produced adverse effects. We concluded that dietary supplements should not be recommended to treat tinnitus but could have a positive outcome on tinnitus reactions in some people. (Source: American Journal of Audiology)
Source: American Journal of Audiology - September 1, 2016 Category: Audiology Source Type: research

Pulsatile tinnitus associated with dehiscent internal carotid artery: An irremediable condition?
We report the case of a 63-year-old patient referred to the Ear, Nose, and Throat (ENT) ward for unbearable pulsatile tinnitus. Otoscopy revealed a normal right tympanic membrane, with pulsatile tinnitus but without hearing impairment. Based on imaging studies, including computed tomography (CT) and magnetic resonance imaging (MRI) of the temporal bone, as well as Doppler ultrasound of the internal carotid artery and sigmoid sinus, the diagnosis of ICA canal dehiscence into the tympanic cavity was established, thus excluding the diagnosis of aberrant ICA. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - August 31, 2016 Category: ENT & OMF Authors: Jean-Philippe Van Damme, G éraldine Heylen, Chantal Gilain, Pierre Garin Source Type: research

An unusual cause of tinnitus.
PMID: 27657313 [PubMed - in process] (Source: Ear, Nose and Throat Journal)
Source: Ear, Nose and Throat Journal - August 31, 2016 Category: ENT & OMF Authors: Chen PJ, Chen HC Tags: Ear Nose Throat J Source Type: research

Comparison of characteristics observed in tinnitus patients with unilateral vs bilateral symptoms, with both normal hearing threshold and distortion-product otoacoustic emissions.
CONCLUSION: Tinnitus characteristics in normal-hearing patients differ between the groups with unilateral and bilateral complaints. OBJECTIVES: The study was to determine the differences between tinnitus characteristics observed in patients with unilateral vs bilateral symptoms and normal hearing threshold, as well as normal results of distortion-product otoacoustic emissions (DPOAEs). METHOD: The patients answered questions concerning tinnitus duration, laterality, character, accompanying symptoms, and circumstances of onset. The results of tympanometry, auditory brainstem responses, tinnitus likeness spectrum, ...
Source: Acta Oto-Laryngologica - August 29, 2016 Category: ENT & OMF Authors: Zagólski O, Stręk P Tags: Acta Otolaryngol Source Type: research

Tinnitus Self-Efficacy and Other Tinnitus Self-Report Variables in Patients With and Without Post-Traumatic Stress Disorder
Conclusions: Tinnitus self-efficacy, along with other self-assessed tinnitus characteristics, varied across groups distinguished by PH diagnoses. In general, individuals with tinnitus and concurrent PTSD reported significantly poorer tinnitus self-efficacy and more handicapping tinnitus effects when compared to individuals with other psychological conditions or those with tinnitus alone. The group differences highlighted the need to consider tinnitus self-efficacy in intervention strategies, particularly for patients with tinnitus and concurrent PTSD as the results reiterated the unique ability of PTSD to interact in power...
Source: Ear and Hearing - August 26, 2016 Category: Audiology Tags: Research Articles Source Type: research

Does multi-modal cervical physical therapy improve tinnitus in patients with cervicogenic somatic tinnitus?
Tinnitus can be related to many different aetiologies such as hearing loss or a noise trauma, but it can also be related to the somatosensory system of the cervical spine, called cervicogenic somatic tinnitus (CST). Case studies suggest a positive effect of cervical spine treatment on tinnitus complaints in patients with CST, but no experimental studies are available. (Source: Manual Therapy)
Source: Manual Therapy - August 24, 2016 Category: Physiotherapy Authors: S. Michiels, P. Van de Heyning, S. Truijen, A. Hallemans, W. De Hertogh Source Type: research

Intraperitoneal curcumin and vitamin E combination for the treatment of cisplatin-induced ototoxicity in Rats
Cisplatin ototoxicity is characterized by irreversible, progressive, bilateral sensorineural hearing loss at high frequencies, accompanied by tinnitus. The aim of this study is to demonstrate the protective action of curcumin alone or in combination with vitamin E against cisplatin-induced ototoxicity in animal models. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - August 22, 2016 Category: ENT & OMF Authors: Harun Soyal ıç, Fikret Gevrek, Sema Koç, Mustafa Avcu, Mehmet Metin, İbrahim Aladağ Source Type: research

Auditory Thalamic Circuits and GABAA Receptor Function: Putative Mechanisms in Tinnitus Pathology.
Abstract Tinnitus is defined as a phantom sound (ringing in the ears), and can significantly reduce the quality of life for those who suffer its effects. Ten to fifteen percent of the general adult population report symptoms of tinnitus with 1-2% reporting that tinnitus negatively impacts their quality of life. Noise exposure is the most common cause of tinnitus and the military environment presents many challenging high-noise situations. Military noise levels can be so intense that standard hearing protection is not adequate. Recent studies suggest a role for inhibitory neurotransmitter dysfunction in response to...
Source: Hearing Research - August 19, 2016 Category: Audiology Authors: Caspary DM, Llano DA Tags: Hear Res Source Type: research

M énière's disease and biographical disruption: Where family transitions collide
Publication date: Available online 18 August 2016 Source:Social Science & Medicine Author(s): Sarah L. Bell, Jessica Tyrrell, Cassandra Phoenix People's lived experiences of chronic illness have garnered increasing research interest over the last 30–40 years, with studies recognising the disruptive influence of illness onset and progression, both to people's everyday lives and to their biographical selves. We extend this body of work, drawing on the experiences of people living with Ménière's disease; a long-term progressive vestibular disorder characterised by unpredictable episodes of debilit...
Source: Social Science and Medicine - August 17, 2016 Category: Psychiatry & Psychology Source Type: research

Occupational hazards survey among coal workers using hand-held vibrating tools in a northern China coal mine
Conclusions This study has identified the main signs and symptoms of HAVS among coal workers exposed to HTV in China. More information related to occupational safety and health programs are required to reduce the risk of HAVS. (Source: International Journal of Industrial Ergonomics)
Source: International Journal of Industrial Ergonomics - August 16, 2016 Category: Occupational Health Source Type: research

Ménière's Disease: Molecular Analysis of Aquaporins 2, 3 and Potassium Channel KCNE1 Genes in Brazilian Patients
Conclusions: The genetic variant rs426496 in AQP2; rs591810 in AQP3 and rs1805127, rs1805128, and rs17173510, in KCNE1 were found in patients with Ménière's disease. The polymorphism rs426496, in AQP2, is associated with tinnitus at the onset of Ménière's disease and altered electronystagmography. In addition, rs1805127, in KCNE1, is associated with the presence of nephropathy. (Source: Otology and Neurotology)
Source: Otology and Neurotology - August 13, 2016 Category: ENT & OMF Tags: Vestibular Disorders Source Type: research

A Historical Recount: Discovering Menière's Disease and Its Association With Migraine Headaches
Conclusions: Although his colleagues discounted Menière's theory concerning migraine headaches, he continued to make deductive inferences and publish his findings, leading to the association of migraine headaches and Menière's disease. Today, this association continues to be debated, adding to Prosper Menière's legacy. (Source: Otology and Neurotology)
Source: Otology and Neurotology - August 13, 2016 Category: ENT & OMF Tags: History of Otology Source Type: research

Temporary and Permanent Noise-induced Threshold Shifts: A Review of Basic and Clinical Observations
Conclusion: Exposure to intense sound can produce TTS, acute changes in hearing sensitivity that recover over time, or PTS, a loss that does not recover to preexposure levels. In general, a threshold shift ≥10 dB at 2, 3, and 4 kHz is required for reporting purposes in human studies. The high-frequency regions of the cochlea are most sensitive to noise damage. Resonance of the ear canal also results in a frequency region of high-noise sensitivity at 4 to 6 kHz. A primary noise target is the cochlear hair cell. Although the mechanisms that underlie such hair cell damage remain unclear, there is evidence to support ...
Source: Otology and Neurotology - August 13, 2016 Category: ENT & OMF Tags: Special Section: Pihl Research Guidance Papers Source Type: research

“Measurement” of Tinnitus
Chronic tinnitus is the persistent sensation of hearing a sound that exists only inside the head. The prevalence of tinnitus in adults in the United States is estimated at 10 to 15%. For about 20% of these individuals the tinnitus is significantly bothersome. Although myriad therapies for tinnitus are offered (often at significant cost), most are not evidence based. Difficulty in the assessment and further development of interventions for tinnitus stems from the limitations of techniques used to evaluate these interventions. Questionnaires are widely available to “measure” (tinnitus can only be indirectly measu...
Source: Otology and Neurotology - August 13, 2016 Category: ENT & OMF Tags: Special Section: Pihl Research Guidance Papers Source Type: research

Transcranial magnetic stimulation for the treatment of epilepsy.
CONCLUSIONS: Overall, we judged the quality of evidence for the primary outcomes of this review to be low. There is evidence that rTMS is safe and not associated with any adverse events, but given the variability in technique and outcome reporting that prevented meta-analysis, the evidence for efficacy of rTMS for seizure reduction is still lacking despite reasonable evidence that it is effective at reducing epileptiform discharges. PMID: 27513825 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 10, 2016 Category: Journals (General) Authors: Chen R, Spencer DC, Weston J, Nolan SJ Tags: Cochrane Database Syst Rev Source Type: research

Associations between long-term serum platinum and neurotoxicity and ototoxicity, endocrine gonadal function, and cardiovascular disease in testicular cancer survivors.
Haugnes HS Abstract OBJECTIVE: To evaluate the associations between long-term serum levels of platinum (se-Pt) and neurotoxicity and ototoxicity (NTX), endocrine gonadal function (endocrine-GF), and cardiovascular disease (CVD) in testicular cancer survivors. MATERIAL AND METHODS: A total of 292 cisplatin-treated testicular cancer survivors (1980-1994) participated in a national follow-up study (2007-2008). Se-Pt was quantified by inductively coupled plasma mass spectrometry, and categorized in quartiles. Symptoms of NTX were assessed with scale for chemotherapy-induced neurotoxicity (SCIN), with each symptom...
Source: Urologic Oncology - August 10, 2016 Category: Urology & Nephrology Authors: Hjelle LV, Bremnes RM, Gundersen PO, Sprauten M, Brydøy M, Tandstad T, Wilsgaard T, Fosså SD, Oldenburg J, Haugnes HS Tags: Urol Oncol Source Type: research

Prevalence of otologic signs and symptoms in adult patients with temporomandibular disorders: a systematic review and meta-analysis
ConclusionThe prevalence of otologic signs and symptoms in adult patients with TMD is high. The most prevalent otologic symptom in patient adults with TMD is ear fullness.Clinical relevanceThis study intends to provide understanding over the prevalence of otologic signs and symptoms in TMD cases in adults. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - August 9, 2016 Category: Dentistry Source Type: research

The Importance of Aging in Gray Matter Changes Within Tinnitus Patients Shown in Cortical Thickness, Surface Area and Volume.
This study explores the structural changes of gray matter using surface base methods and focuses more specifically on changes in cortical thickness in 127 tinnitus patients. The linear relationships between cortical thickness and behavioral measures including aging, tinnitus loudness, tinnitus duration, tinnitus distress, and hearing loss were analyzed. Three dimensional T1-weighted MR images were acquired and cortical gray matter volumes were segmented using FreeSurfer on Talairach space. The results showed that cortical thickness and volume are negatively correlated to age in widespread regions of frontal cortices, and p...
Source: Brain Topography - August 9, 2016 Category: Neuroscience Authors: Yoo HB, De Ridder D, Vanneste S Tags: Brain Topogr Source Type: research

Different infusion durations for preventing platinum-induced hearing loss in children with cancer.
CONCLUSIONS: Since only one eligible RCT evaluating the use of a continuous cisplatin infusion versus a one-hour bolus cisplatin infusion was found, and that had methodological limitations, no definitive conclusions can be made. It should be noted that 'no evidence of effect', as identified in this review, is not the same as 'evidence of no effect'. For other (combinations of) infusion durations and other platinum analogues no eligible studies were identified. More high quality research is needed. PMID: 27498707 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 7, 2016 Category: Journals (General) Authors: van As JW, van den Berg H, van Dalen EC Tags: Cochrane Database Syst Rev Source Type: research

The Role of Trace Elements in Tinnitus.
In this study, we aimed to investigate the role of three trace elements, namely, zinc, copper, and lead, in tinnitus by analyzing the serum level of copper and lead and both the serum and tissue level of zinc. Eighty patients, who applied to outpatient otolaryngology clinic with the complaints of having tinnitus, and 28 healthy volunteers were included. High-frequency audiometry was performed, and participants who had hearing loss according to the pure tone average were excluded; tinnitus frequency and loudness were determined and tinnitus reaction questionnaire scores were obtained from the patients. Of all the participan...
Source: Biological Trace Element Research - August 7, 2016 Category: Biology Authors: Yaşar M, Şahin Mİ, Karakükçü Ç, Güneri E, Doğan M, Sağıt M Tags: Biol Trace Elem Res Source Type: research

EP 50. High frequency stimulation of the rat dorsal cochlear nucleus inhibits tinnitus
Tinnitus can cause a serious burden on patients and remains often treatment-resistant. Up to date no standard effective treatment is available. Deep brain stimulation (DBS) has been widely applied for various neurological disorders, most often in patients with Parkinson ’s disease. There is growing evidence that deep brain stimulation might be able to interrupt the local altered neuronal activity found in tinnitus and hereby inhibit tinnitus perception. Multiple preclinical and clinical studies suggest that the dorsal cochlear nucleus (DCN) plays an important rol e in the development of tinnitus and could therefore b...
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: G. van Zwieten, J. Smit, A. Jahanshahi, R. Stokroos, Y. Temel Source Type: research

Tinnitus- related distress: evidence from fMRI of an emotional stroop task
Chronic tinnitus affects 5  % of the population, 17 % suffer under the condition. This distress seems mainly to be dependent on negative cognitive-emotional evaluation of the tinnitus and selective attention to... (Source: BMC Ear, Nose and Throat Disorders)
Source: BMC Ear, Nose and Throat Disorders - August 5, 2016 Category: ENT & OMF Authors: Dennis Golm, Carsten Schmidt-Samoa, Peter Dechent and Birgit Kr öner-Herwig Source Type: research

Demographic data, referral patterns and interventions used for children and adolescents with tinnitus and hyperacusis in Denmark
To investigate whether children and adolescents with tinnitus and/or hyperacusis are seen in Ear-Nose-Throat (ENT) clinics and to report the clinical data, treatment and referral patterns of these children. To describe the population of children and adolescents with tinnitus and/or hyperacusis found in Educational- Psychological Advisory services (EPAs) and Centres for special Education for Adults (CEAs) and to identify the referral patterns and interventions used for the children in each of these settings. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - August 4, 2016 Category: ENT & OMF Authors: Susanne Nemholt Rosing, Anestis Kapandais, Jesper Hvass Schmidt, David M. Baguley Source Type: research

Intratympanic corticosteroids injections: a systematic review of literature
The objective of the study was to determine the evidence of intratympanic steroids injections (ITSI) for efficacy in the management of the following inner ear diseases: M énière’s disease, tinnitus, noise-induced hearing loss (NIHL) and idiopathic sudden sensorineural hearing loss (ISSNHL). The data sources were literature review from 1946 to December 2014, PubMed and Medline. A systematic review of the existing literature was performed. Databases were searched f or all human prospective randomized clinical trials using ITSI in at least one treatment group. The authors identified 29 prospective randomiz...
Source: European Archives of Oto-Rhino-Laryngology - August 4, 2016 Category: ENT & OMF Source Type: research

A case series of a magnetic bone conduction hearing implant.
The objective of the study was to retrospectively review the postoperative outcomes of patients from a single centre who were implanted with a magnetic bone conduction hearing implant system. The medical and audiological case notes of all patients (n = 34) in a tertiary referral centre ENT department who had been implanted with a Baha® 4 Attract System between October 2013 and April 2015 were reviewed retrospectively. The main outcome measures were use of the aid and complications from implantation or use of the aid. Results indicated that 23 patients had no significant postoperative problems; 5 required an alteration ...
Source: Annals of the Royal College of Surgeons of England - August 3, 2016 Category: Surgery Authors: Reddy-Kolanu R, Gan R, Marshall AH Tags: Ann R Coll Surg Engl Source Type: research

Comprehensive Audiometric Analysis of Hearing Impairment and Tinnitus After Cisplatin-Based Chemotherapy in Survivors of Adult-Onset Cancer [Treatment-Related Complications]
Purpose Cisplatin is widely used but highly ototoxic. Effects of cumulative cisplatin dose on hearing loss have not been comprehensively evaluated in survivors of adult-onset cancer. Patients and Methods Comprehensive audiological measures were conducted on 488 North American male germ cell tumor (GCT) survivors in relation to cumulative cisplatin dose, including audiograms (0.25 to 12 kHz), tests of middle ear function, and tinnitus. American Speech-Language-Hearing Association criteria defined hearing loss severity. The geometric mean of hearing thresholds (0.25 to 12 kHz) summarized overall hearing status consistent wi...
Source: Journal of Clinical Oncology - August 2, 2016 Category: Cancer & Oncology Authors: Frisina, Wheeler, Fossa, Kerns, Fung, Sesso, Monahan, Feldman, Hamilton, Vaughn, Beard, Budnick, Johnson, Ardeshir-Rouhani-Fard, Einhorn, Lipshultz, Dolan, Travis Tags: Chemotherapy, Outcomes Research Treatment-Related Complications Source Type: research

Does stapes surgery improve tinnitus in patients with otosclerosis?
Conclusion Low pitch tinnitus is more likely to be resolved after stapedotomy for patients with otosclerosis. High pitch tinnitus may not resolve even after closure of the Air-Bone Gap at tinnitus frequencies. (Source: Brazilian Journal of Otorhinolaryngology)
Source: Brazilian Journal of Otorhinolaryngology - August 2, 2016 Category: ENT & OMF Source Type: research

Platinum-induced hearing loss after treatment for childhood cancer.
CONCLUSIONS: This systematic review shows that children treated with platinum analogues are at risk for developing hearing loss, but the exact prevalence and risk factors remain unclear. There were no data available for tinnitus. Based on the currently available evidence we can only advise that children treated with platinum analogues are screened for ototoxicity in order to make it possible to diagnose hearing loss early and to take appropriate measures. However, we are unable to give recommendations for specific follow-up protocols including frequency of testing. Counselling regarding the prevention of noise pollution ca...
Source: Cochrane Database of Systematic Reviews - August 2, 2016 Category: Journals (General) Authors: van As JW, van den Berg H, van Dalen EC Tags: Cochrane Database Syst Rev Source Type: research

Annie Award Recognizes Hearing Education Awareness for Rockers
Hearing Education Awareness for Rockers (HEAR), a nonprofit organization dedicated to “the prevention of hearing loss and tinnitus among musicians, other music professionals, and all music fans (especially teens and young adults) through education and grass-roots advocacy,” will receive ASHA’s 2016 Annie Glenn Award. (Source: The ASHA Leader Online)
Source: The ASHA Leader Online - August 1, 2016 Category: Speech Therapy Source Type: research

The Tinnitus-Traumatic Brain Injury Link: What is the role of the audiologist in patient care, treatment and coping strategies?
(Source: The ASHA Leader Online)
Source: The ASHA Leader Online - August 1, 2016 Category: Speech Therapy Source Type: research

Analysis of Outcome Domains in Adult Cochlear Implantation: A Systematic Review
Conclusions An analysis of randomized controlled trials studying cochlear implantation in adults yielded a wide spectrum of outcome domains. This is the first study to comprehensively describe the breadth of outcome domains in adult cochlear implantation. Validated instruments from these domains could be considered for potential inclusion as quality measures and registry use. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - July 31, 2016 Category: ENT & OMF Authors: Vila, P. M., Hullar, T. E., Buchman, C. A., Lieu, J. E. C. Tags: Review Articles Source Type: research

The Persistence of Tinnitus after Acoustic Neuroma Surgery
Objective Examine possible prognostic factors for the persistence of tinnitus after acoustic neuroma resection. Study Design Case series with chart review. Setting Tertiary academic medical center. Subjects and Methods The records of 166 patients who underwent acoustic neuroma resection from 2009 to 2014 were reviewed. Patients were asked to complete a survey, including the Tinnitus Handicap Inventory, 1 to 6 years postoperatively. Results Of the 53 patients who completed the survey, 17% reported that their tinnitus resolved; 9% reported improvement; 23% reported no change; 43% reported that their tinnitus worsened; an...
Source: Otolaryngology - Head and Neck Surgery - July 31, 2016 Category: ENT & OMF Authors: Bell, J. R., Anderson-Kim, S. J., Low, C., Leonetti, J. P. Tags: Otology and Neurotology Source Type: research

Evidence of activity-dependent plasticity in the dorsal cochlear nucleus, in  vivo, induced by brief sound exposure.
We examined the levels of multi- and single-unit spontaneous activity before and immediately following brief exposure (2 min) to tones at levels of either 109 or 85 dB SPL. Exposure frequency was selected to either correspond to the units' best frequency (BF) or fall within the borders of its inhibitory side band. The results demonstrate that these exposure conditions caused significant alterations in spontaneous activity and responses to BF tones. The induced changes have a fast onset (minutes) and are persistent for durations of at least 20 min. The directions of the change were found to depend on the freq...
Source: Hearing Research - July 31, 2016 Category: Audiology Authors: Gao Y, Manzoor N, Kaltenbach JA Tags: Hear Res Source Type: research

Effects on auditory function of chronic exposure to electromagnetic fields from mobile phones.
Abstract The widespread use of mobile phones has given rise to apprehension regarding the possible hazardous health effects of high-frequency electromagnetic fields (EMFs) on auditory function. We conducted a study to investigate the effects of long-term (>4 yr) exposure to EMFs emitted by mobile phones on auditory function. Our study population was made up of 40 healthy medical students-31 men and 9 women, aged 20 to 30 years (mean 22.7). Of this group, 31 subjects typically held their phone to the right ear and 9 to the left ear; the non-phone-using ear served as each subject's control ear. The phone-using su...
Source: Ear, Nose and Throat Journal - July 31, 2016 Category: ENT & OMF Authors: Bhagat S, Varshney S, Bist SS, Goel D, Mishra S, Jha VK Tags: Ear Nose Throat J Source Type: research

When alarm bells ring: emergency tinnitus.
CONCLUSIONS: Tinnitus, mainly linked to loss of hearing, is a frequent symptom among the population at large. About 7% of those affected by tinnitus turn to their doctor to solve their problem, while between 0.5 and 2% request urgent medical assistance. Their cry for help may be the result of an acute onset of tinnitus or the rapid impairment of an already chronic condition. Tinnitus is not considered an urgent ear, nose and throat (ENT) condition by the Associazione Otorinolaringologi Ospedalieri Italiani (AOOI) [Italian Association of Hospital ENT], even though there are many pathological conditions, sometimes serious, a...
Source: European Review for Medical and Pharmacological Sciences - July 29, 2016 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

O-032 Venous Blood Flow Visualization in Sigmoid Sinus Diverticulum Using MRI
ConclusionPT caused by SSD may be caused by a unique flow pattern in the SSD and sinuses as visualized on both MRV and CFD.Abstract O-032 Figure 1Townes projection CFD analysis of a patient with a left SSD and an upstream stenosis in the transverse sinus. The pretreatment analysis (A) shows a jet of flow from the stenosis into the SSD (arrow), vortex of flow in the SSD (double arrow), and a vortex component of flow in the sigmoid sinus down-stream from the SSD (arrow head). The post-treatment model (B) shows absence of the flow in the SSD as well as decreased vortex component of flow in down-stream sigmoid sinusDisclosures...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Amans, M., Kao, E., Kefayati, S., Meisel, K., Faraji, F., Glastonbury, C., Ballweber, M., Halbach, V., Saloner, D. Tags: Oral abstracts Source Type: research

O-033 Jugular Vein Flow Patterns in Patients with Pulsatile Tinnitus Using Computational Fluid Dynamics
ConclusionThe geometry of the jugular vein significantly affects the position, size, and length of the vortex cores. Our results suggest a link between geometry, flow, and PT.Abstract O-033 Figure 1Visualization of streamlines (A, B) and vortex cores by swirling strength (C, D) in internal jugular veins of subjects without (A, C) and with (B, D) PT. White arrows (A, B) reperent the general re-direction of flow from the sigmoid sinus into the jagular vein as dictated by the shape of the junction with the jugular bulb (red lines). Subjects without PT have strong vortex cores in jugular bulb (C, red arrows), while those with ...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Kao, E., Kefayati, S., Meisel, K., Ballweber, M., Faraji, F., Halbach, V., Saloner, D., Amans, M. Tags: Oral abstracts Source Type: research

P-024 Prominent Condylar Veins Causing Pulsatile Tinnitus: Dynamic Angiographic Confirmation
ConclusionProminent flow in condylar veins should be considered among the numerous causes of PT. This may be a frequent cause of these symptoms in patients who previously would have had no identifiable cause Further investigation is warranted with respect to this cause of PT and PT in general.DisclosuresM. Alexander: None. K. Meisel: None. V. Halbach: None. R. Darflinger: None. A. Nicholson: None. F. Settecase: None. D. Cooke: None. R. Higashida: None. C. Dowd: None. S. Hetts: None. M. Amans: None. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Alexander, M., Meisel, K., Halbach, V., Darflinger, R., Nicholson, A., Settecase, F., Cooke, D., Higashida, R., Dowd, C., Hetts, S., Amans, M. Tags: Oral poster abstracts Source Type: research

P-029 Turbulent Flow in the Venous Outflow Tract of Pulsatile Tinnitus Patients with Sigmoid Sinus Diverticulum
ConclusionThe unique flow patterns and the presence of turbulence introduced by the TSS and SSD may help explain PT in these patients. Treatment of TSS with PTA and stent implantation, or treatment of the SSD with coil embolization can potentially alter the TKE level and pattern.DisclosuresS. Kefayati: None. E. Kao: None. J. Liu: None. H. Haraldsson: None. F. Faraji: None. M. Ballweber: None. K. Meisel: None. V. Halbach: None. D. Saloner: None. M. Amans: None. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Kefayati, S., Kao, E., Liu, J., Haraldsson, H., Faraji, F., Ballweber, M., Meisel, K., Halbach, V., Saloner, D., Amans, M. Tags: Oral poster abstracts Source Type: research

E-008 Patient Outcomes Following Treatment of High Flow Vascular Lesions of the Anterior Cranial Fossa and Orbit
ConclusionsHFVL are uncommon lesions that are challenging to treat. Endovascular embolization alone or in combination with surgery results in HFVL obliteration in 50% of patients with an acceptable safety profile. Further studies should determine whether radiosurgery alone or in combination with endovascular embolization results in high rates of HFVL cure.Abstract E-008 Figure 1DisclosuresA. Moraff: None. R. Dodd: None. M. Marks: None. H. Do: None. G. Steinberg: None. S. Chang: None. J. Heit: None. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Moraff, A., Dodd, R., Marks, M., Do, H., Steinberg, G., Chang, S., Heit, J. Tags: Electronic poster abstracts Source Type: research

E-009 A Novel Transvenous Approach to Embolization of an Extensive Transverse and Sigmoid Sinus DAVM in a Patient with an Occluded Ipsilateral Internal Jugular Vein
We describe the case of a patient who presented with left-sided pulsatile tinnitus. Initial cerebral angiogram demonstrated an extensive DAVM of the left transverse and sigmoid sinuses being supplied primarily by branches of the left internal carotid, middle meningeal, and occipital arteries and the right occipital artery. We also observed cortical venous reflux compatible with venous hypertension. Given the extensive arterial supply, a transvenous approach to treatment was chosen. Upon attempted catheterization of the left internal jugular vein (IJ), we discovered that it was occluded up to the level of its junction with ...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Adix, M., Choi, I., Kaminsky, I. Tags: Electronic poster abstracts Source Type: research

An electromyography guided botulinum toxin injection is effective treatment for objective tinnitus as an office procedure: A case report
We present a case of pulsatile tinnitus who was effectively treated with BTX injection under an electromyography guidance as an office procedure. (Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences)
Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences - July 27, 2016 Category: ENT & OMF Source Type: research

Noise-induced hearing loss: Neuropathic pain via Ntrk1 signaling
Publication date: Available online 26 July 2016 Source:Molecular and Cellular Neuroscience Author(s): Senthilvelan Manohar, Kimberly Dahar, Henry J. Adler, Ding Dalian, Richard Salvi Severe noise-induced damage to the inner ear leads to auditory nerve fiber degeneration thereby reducing the neural input to the cochlear nucleus (CN).Paradoxically, this leads to a significant increase in spontaneous activity in the CN which has been linked to tinnitus, hyperacusis and ear pain.The biological mechanisms that lead to an increased spontaneous activity are largely unknown, but could arise from changes in glutamatergic or ...
Source: Molecular and Cellular Neuroscience - July 25, 2016 Category: Neuroscience Source Type: research

Sudden Sensorioneural Hearing Loss and Autoimmune Systemic Diseases
Conclusion In our sample of patients with sudden SNHL, the prevalence of SAD was found relevant. The majority had tinnitus and dizziness concomitant hearing loss, unilateral involvement and had experienced profound hearing loss at the time of the installation. In spite of instituted treatment, most cases showed no improvement in audiometric thresholds. Apparently, patients with sudden SNHL and SAD have a more severe initial impairment, higher percentage of bilateral, lower response to treatment, and worse prognosis than patients with sudden SNHL of unknown etiology.[...]Thieme Publicações Ltda Rio de Jan...
Source: International Archives of Otorhinolaryngology - July 25, 2016 Category: ENT & OMF Authors: Rossini, Bruno Almeida Antunes Penido, Norma de Oliveira Munhoz, Mario Sergio Lei Bogaz, Eduardo Amaro Curi, Renata Souza Tags: Original Research Source Type: research

Reliability and validity of the Lithuanian Tinnitus Handicap Inventory
Conclusions The results suggest that the Lithuanian version of THI maintains its original validity and may serve as reliable and valid measure of general tinnitus related distress that can be used in a clinical setting to quantify the impact of tinnitus on daily living. (Source: Medicina)
Source: Medicina - July 22, 2016 Category: Journals (General) Source Type: research

The effect of intratympanic gentamicin for treatment of M énière’s disease on lower frequency hearing
Conclusion Our results indicate that intratympanic gentamicin especially affects the mean pure tone audiometry threshold in the low frequency range, which may have clinical implications. Though many of our results are (statistically) substantial the study was limited by the small cohort size. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - July 21, 2016 Category: Drugs & Pharmacology Source Type: research