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Tinnitus services in the United Kingdom: a survey of patient experiences
Tinnitus service provision in the United Kingdom has been investigated from the healthcare provider ’s perspective demonstrating considerable regional variation particularly regarding availability of psychologi... (Source: BMC Health Services Research)
Source: BMC Health Services Research - February 13, 2018 Category: General Medicine Authors: Don McFerran, Derek J. Hoare, Simon Carr, Jaydip Ray and David Stockdale Tags: Research article Source Type: research

Erratum to: Long-term changes in multimodal intensive tinnitus therapy. A  5-year follow-up.
Erratum to: Long-term changes in multimodal intensive tinnitus therapy. A 5-year follow-up. HNO. 2018 Feb 09;: Authors: Brüggemann P, Otto J, Lorenz N, Schorsch S, Szczepek AJ, Böcking B, Mazurek B Abstract Erratum to:HNO 2018 66 (Suppl):S34-S38 https://doi.org/10.1007/s00106-017-0463-4 Figure 1 was published incorrectly in the online version of this paper. The correct Figure is reproduced below. PMID: 29426995 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - February 12, 2018 Category: ENT & OMF Tags: HNO Source Type: research

[Smartphone app-supported approaches to tinnitus therapy].
Authors: Hesse G Abstract In recent years, applications (apps) for medical purposes have been developed and introduced, including apps that perform diagnostics and documentation for hearing loss and tinnitus in combination with smartphones. Even therapeutic apps, particularly for chronic tinnitus, have been launched. This review discusses the existing scientific literature for these smartphone applications. For tinnitus, Internet-based cognitive behavioral therapy has been developed and evaluated. For tinnitus therapy, introduced apps combine acoustic stimulation and music, or serve acoustic stimulation of cortical...
Source: HNO - February 10, 2018 Category: ENT & OMF Tags: HNO Source Type: research

[Current aspects of tinnitus and depression].
Authors: Kratzsch V, Goebel G Abstract Health authorities underestimate the negative influence of emotional factors such as depression, anxiety disorders, or somatoform disorders in the development of tinnitus and their contribution to a poor prognosis. This can lead to underestimation of the impairment suffered by tinnitus patients and, consequently, a possibly incorrect treatment approach or belated initiation of therapy. Mental disorders play a large role in the S3AWMF "Tinnitus" guidelines. Thus, the somatic and psychiatric approaches for treatment of chronic tinnitus patients are combi...
Source: HNO - February 10, 2018 Category: ENT & OMF Tags: HNO Source Type: research

[Tinnitus  - New challenge and therapeutic approaches. German version].
[Tinnitus - New challenge and therapeutic approaches. German version]. HNO. 2018 Feb 07;: Authors: Mazurek B PMID: 29417190 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - February 10, 2018 Category: ENT & OMF Tags: HNO Source Type: research

Effects of Anxiety Sensitivity and Hearing Loss on Tinnitus Symptom Severity.
Authors: Moon KR, Park S, Jung Y, Lee A, Lee JH Abstract Objective: The aim of the present study was to examine the relative role of anxiety sensitivity and hearing loss on the tinnitus symptoms severity in a large clinical sample of patients with tinnitus. Methods: A total of 1,705 patients with tinnitus who visited the tinnitus clinic underwent the pure-tone audiometric testing and a battery of self-report questionnaires. Multiple linear regression analyses were performed to identify the relationship of anxiety sensitivity and hearing loss to tinnitus symptoms severity. Results: Both anxiety sensitivity a...
Source: Psychiatry Investigation - February 10, 2018 Category: Psychiatry Tags: Psychiatry Investig Source Type: research

Comparison of the Transient Evoked Otoacoustic Emissions (TEOAEs) and Distortion Products Otoacoustic Emissions (DPOAEs) in Normal Hearing Subjects With and Without Tinnitus
AbstractThe aim of this study was to investigate the possible role of cochlear outer hair cell function with TEOAE and DPOAE tests in patients with normal hearing and tinnitus. 25 tinnitus patients with normal hearing sensitivity selected as study group. Control group consist of 50 normal hearing subjects without tinnitus. All subjects had thresholds below 25 dBHL at frequencies 250 –8,000 Hz, tympanogram type A and normal acoustic reflex thresholds. TEOAE were recorded with click stimulus at 80 dB SPL at 1,000, 2,000, 3,000 and 4000 Hz. DPOAE were measured at frequencies 1,000–8,000 Hz and inten...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - February 9, 2018 Category: ENT & OMF Source Type: research

Up-regulation of Ca2+/CaMKII/CREB signaling in salicylate-induced tinnitus in rats.
Abstract The purpose of the study was to investigate the changes of Ca2+/calmodulin-dependent protein kinases II (CaMKII)/cAMP response element-binding protein (CREB) signaling pathway in a rat tinnitus model. Eighteen Wistar rats were randomly divided into three groups: normal control (NC), normal saline (NS), and tinnitus model (TM) groups. Tinnitus model was induced by intraperitoneal injection of salicylate. The concentration of intracellular calcium level in auditory cortex cells was determined using Fura-2 acetoxymethyl ester (Fura-2 AM) method with fluorospectrophotometer. Expressions of calmodulin (CaM), N...
Source: Molecular and Cellular Biochemistry - February 9, 2018 Category: Biochemistry Authors: Zhao J, Wang B, Wang X, Shang X Tags: Mol Cell Biochem Source Type: research

CTA/V detection of bilateral sigmoid sinus dehiscence and suspected idiopathic intracranial hypertension in unilateral pulsatile tinnitus
AbstractPurposeThis aimed to evaluate the prevalence and extent of bilateral sigmoid sinus dehiscence (SSD) and to explore the presence of idiopathic intracranial hypertension (IIH) in patients with unilateral pulsatile tinnitus (PT) with CTA/V.MethodsSixty PT patients (52 females; 40.4  ± 11.6 years [20–72]) who underwent CTA/V and 30 non-PT patients (27 females; 38.4 ± 14.7 years [12–62]) were enrolled in this study. The primary outcome measure was the radiographic presence of SSD. The index of transverse sinus stenosis (ITSS) was obtained by multiplying the ste...
Source: Neuroradiology - February 7, 2018 Category: Radiology Source Type: research

Tinnitus, depression, and suicidal ideation in adults: A nationally representative general population sample
Publication date: March 2018 Source:Journal of Psychiatric Research, Volume 98 Author(s): Kyu-Man Han, Young-Hoon Ko, Cheolmin Shin, Jae-Hon Lee, June Choi, Do-Young Kwon, Ho-Kyoung Yoon, Changsu Han, Yong-Ku Kim Tinnitus is strongly associated with psychiatric symptoms, including depression and suicidality. We aimed to further investigate the association of tinnitus with depressive mood and/or suicidal ideation, and explore the shared risk factors for these within a representative sample of the adult general population. We also investigated potential mediation pathways among tinnitus, suicidal ideation, depression, share...
Source: Journal of Psychiatric Research - February 7, 2018 Category: Psychiatry Source Type: research

H örsturz mit Surditas, Schwindel und Tinnitus - eine 12-jährige Odyssee
Laryngo-Rhino-Otol DOI: 10.1055/s-0044-100517 © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: Laryngo- Rhino- Otologie)
Source: Laryngo- Rhino- Otologie - February 7, 2018 Category: ENT & OMF Authors: Plontke, Plontke K Rahne, Torsten K ösling, Sabrina Tags: Der interessante Fall Source Type: research

Effects of AUT00063, a Kv3.1 channel modulator, on noise-induced hyperactivity in the dorsal cochlear nucleus.
Abstract The purpose of this study was to test whether a Kv3 potassium channel modulator, AUT00063, has therapeutic potential for reversing noise-induced increases in spontaneous neural activity, a state that is widely believed to underlie noise-induced tinnitus. Recordings were conducted in noise exposed and control hamsters from dorsal cochlear nucleus (DCN) fusiform cells before and following intraperitoneal administration of AUT00063 (30 mg/kg). Fusiform cell spontaneous activity was increased in sound-exposed animals, approximating levels that were nearly 50% above those of controls. Administration of AUT00...
Source: Hearing Research - February 7, 2018 Category: Audiology Authors: Glait L, Fan W, Stillitano G, Sandridge S, Pilati N, Large C, Alvaro G, Kaltenbach JA Tags: Hear Res Source Type: research

Drug-Induced Ototoxicity: Diagnosis and Monitoring
AbstractOtotoxicity diagnosis and management has historically been approached using a variety of methods. However, in recent years a consensus on useful and practical approaches has been developed through clinical guidelines of the American Speech Language Hearing Association, the American Academy of Audiology, and multiple clinical trials published in peer-reviewed literature. Some of the guidelines and approaches are used to detect and monitor ototoxicity, while others are used to grade adverse events. Some of the audiologic measures are primary, while others are adjunct measures and may be tailored to the specific needs...
Source: Drug Safety - February 6, 2018 Category: Drugs & Pharmacology Source Type: research

Kv3 K+ currents control spike-timing in dorsal cochlear nucleus principal cells.
In conclusion, modulation of putative Kv3 K+ currents may restore regular spike-timing of DCN fusiform cell firing following noise exposure, and could provide a means to restore deficits in temporal encoding observed during noise-induced tinnitus. PMID: 29421326 [PubMed - as supplied by publisher] (Source: Neuropharmacology)
Source: Neuropharmacology - February 5, 2018 Category: Drugs & Pharmacology Authors: Olsen T, Capurro A, Pilati N, Large C, Hamann M Tags: Neuropharmacology Source Type: research

Hyperacusis: major research questions.
CONCLUSION: This clinical/researcher-led project identified major research questions in hyperacusis. A further development to identify patient-prioritized research will follow. PMID: 29392341 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - February 4, 2018 Category: ENT & OMF Tags: HNO Source Type: research

Improving the Quality of Life of Tinnitus Patients
No abstract available (Source: The Hearing Journal)
Source: The Hearing Journal - February 1, 2018 Category: Audiology Tags: Journal Club Source Type: research

Tinnitus, Hyperacusis, and the Autonomic Nervous System
No abstract available (Source: The Hearing Journal)
Source: The Hearing Journal - February 1, 2018 Category: Audiology Tags: Hearing Matters Source Type: research

The Audiology of Otosclerosis
Diagnostic audiologic procedures for otosclerosis are effective tools in identifying this condition. Audiometric data usually demonstrate a conductive hearing loss at the early stages of otosclerosis. Modern middle ear analysis procedures are becoming more popular in the better diagnosis of otosclerosis. In clinical practice, cochlear otosclerosis can also be observed. Audiologic rehabilitation of otosclerosis includes fitting of hearing aids and implantable hearing devices. Current hearing technology enables patients who do not pursue surgical correction to function well and significantly improve their communication and q...
Source: Otolaryngologic clinics of North America - February 1, 2018 Category: ENT & OMF Authors: Ali A. Danesh, Navid Shahnaz, James W. Hall Source Type: research

The relation between flocculus volume and tinnitus after cerebellopontine angle tumor surgery.
CONCLUSIONS: The lack of a relation between flocculus volumes and the presence of tinnitus, combined with the significant correlation between tinnitus severity and flocculus volumes, suggests that the flocculus may not be the primary source of tinnitus, but is likely to mediate tinnitus severity. The reduced ipsi-to-contralateral volume ratio in patients with gaze-modulated tinnitus suggests that atrophy of the flocculus on the surgery side triggers cross-modal interactions leading to modulation of tinnitus. PMID: 29398141 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - January 31, 2018 Category: Audiology Authors: Mennink LM, Van Dijk JMC, Van Der Laan BFAM, Metzemaekers JDM, Van Laar PJ, Van Dijk P Tags: Hear Res Source Type: research

Commentary on “Clinical and audiologic characteristics of patients with sensorineural tinnitus and its association with psychological aspects: an analytic retrospective study”
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 29, 2018 Category: ENT & OMF Source Type: research

Hearing loss and tinnitus in survivors with chemotherapy-induced neuropathy.
CONCLUSIONS: Our findings suggest that compared to survivors with only CIN, survivors with CIN/HL/TIN are at increased risk for the most severe symptom burden, significant problems associated with sensory loss and changes in balance, as well as significant decrements in all aspects of QOL. PMID: 29353626 [PubMed - in process] (Source: European Journal of Oncology Nursing)
Source: European Journal of Oncology Nursing - January 24, 2018 Category: Nursing Authors: Miaskowski C, Paul SM, Mastick J, Schumacher M, Conley YP, Smoot B, Abrams G, Kober KM, Cheung S, Henderson-Sabes J, Chesney M, Mazor M, Wallhagen M, Levine JD Tags: Eur J Oncol Nurs Source Type: research

[Female patient with pulsatile tinnitus].
Authors: Biber F, Nolte CH, Albers AE PMID: 29350238 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - January 21, 2018 Category: ENT & OMF Tags: HNO Source Type: research

Long-term changes in multimodal intensive tinnitus therapy : A 5 ‑year follow-up.
CONCLUSION: The results of the present study support the effectiveness of the 7‑day multimodal intensive therapy for tinnitus. Posttreatment improvements were related to both tinnitus burden as well as stress and depressive symptoms and were maintained at the 5‑year follow-up. PMID: 29350237 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - January 21, 2018 Category: ENT & OMF Tags: HNO Source Type: research

Prevalence of tinnitus according to temporomandibular joint disorders and dental pain: The Korean National Population ‐based Study
Summary Some studies have reported that temporomandibular joint disorder (TMD) is related to tinnitus. However, there is no study of the relationship and prevalence of dental pain and tinnitus. We evaluated the associations between the prevalence of tinnitus and TMD and dental pain by analysing the Korean national health survey. We analysed totally 11 745 participants. The presence of tinnitus, TMD symptoms and dental pain was surveyed by self‐assessment questionnaires from all the participants. Multivariable regression analysis was applied to acquire odds ratios (OR) and 95% confidence intervals (CI). The prevalenc...
Source: Journal of Oral Rehabilitation - January 21, 2018 Category: Dentistry Authors: Y. H. Kim, Y. G. Park, K. D. Han, D. Vu, K. H. Cho, S. Y. Lee Tags: ORIGINAL ARTICLE Source Type: research

Degree of tinnitus improvement with stapes surgery – a review
Conclusion We conclude that stapes surgery is effective for the treatment of tinnitus (average improvement is 85.52%), and hearing loss (average improvement is 93%). When deciding about the surgical indication in patients with otosclerosis, the presence and level tinnitus should be considered as well as the level of hearing. (Source: Brazilian Journal of Otorhinolaryngology)
Source: Brazilian Journal of Otorhinolaryngology - January 19, 2018 Category: ENT & OMF Source Type: research

Sensory systems: Bimodal cochlear nucleus stimulation alleviates tinnitus
Sensory systems: Bimodal cochlear nucleus stimulation alleviates tinnitus, Published online: 19 January 2018; doi:10.1038/nrneurol.2018.1Sensory systems: Bimodal cochlear nucleus stimulation alleviates tinnitus (Source: Nature Reviews Neurology)
Source: Nature Reviews Neurology - January 19, 2018 Category: Neurology Authors: Heather Wood Source Type: research

Alteration of auditory function in type 2 diabetic and pre-diabetic patients.
CONCLUSIONS: Diabetes is associated with bilateral sensorineural hearing loss, especially at high frequencies. While pre-diabetes is not necessarily associated with significant hearing loss, there may be cochlear malfunction, as indicated by DPOAEs. Thus, patients with pre-diabetes who have tinnitus may benefit from DPOAEs and PTA tests. PMID: 29347860 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - January 18, 2018 Category: ENT & OMF Authors: Li J, Zhang Y, Fu X, Bi J, Li Y, Liu B, Zhang L Tags: Acta Otolaryngol Source Type: research

Prevalence of Hearing Loss and Hearing Care Use Among Asian Americans: A Nationally Representative Sample
Objective: To assess the prevalence of hearing loss and factors affecting hearing care use among Asian Americans, using the first nationally representative sample of Asian Americans. Study Design: National cross-sectional survey. Setting: Ambulatory examination centers. Patients: Three thousand six hundred twelve adults (522 Asian American) aged 20 to 69 in the 2011 to 2012 National Health and Examination Survey with pure-tone audiometry. Main Outcome Measure(s): Percentage with hearing loss, undertaking a hearing test before the study, and hearing aid use. Hearing loss was defined as better hearing ear speec...
Source: Otology and Neurotology - January 17, 2018 Category: ENT & OMF Tags: Sensorineural Hearing Loss and Tinnitus Source Type: research

Relationship Between the Extent of Endolymphatic Hydrops and the Severity and Fluctuation of Audiovestibular Symptoms in Patients With Menière's Disease and MRI Evidence of Hydrops
Conclusion: The ELH was progressive in the long-term course of the disease in this large population of definite MD patients, but short-term and middle-term fluctuations of the symptom severity did not involve measurable variations of the ELH. Furthermore, the symptom severity did not decrease with increasing disease duration. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 17, 2018 Category: ENT & OMF Tags: Vestibular Disorders Source Type: research

Investigation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and mean platelet volume in patients with tinnitus.
This study aimed to evaluate patients with tinnitus in terms of mean platelet volume and platelet distribution width, and to explore neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, recently reported in the literature as being possible inflammation markers. METHODS: This study comprised 64 tinnitus patients and 64 age-matched healthy controls. Statistical significance level was accepted as p
Source: Journal of Laryngology and Otology - January 16, 2018 Category: ENT & OMF Tags: J Laryngol Otol Source Type: research

Strategies for a  regenerative therapy of hearing loss.
Strategies for a regenerative therapy of hearing loss. HNO. 2018 Jan 09;: Authors: Diensthuber M, Stöver T Abstract Despite impressive technical progress in the field of conventional hearing aids and implantable hearing systems, the hopes for the treatment of inner ear diseases such as hearing loss and tinnitus have become increasingly directed toward regenerative therapeutic approaches. This review discusses the currently most promising strategies for hair cell regeneration in the inner ear to treat hearing loss, including stem cell-based, gene transfer-based, and pharmacological interventio...
Source: HNO - January 11, 2018 Category: ENT & OMF Tags: HNO Source Type: research

Prevalence of Hearing Loss and Hearing Care Use Among Asian Americans: A Nationally Representative Sample
Objective: To assess the prevalence of hearing loss and factors affecting hearing care use among Asian Americans, using the first nationally representative sample of Asian Americans. Study Design: National cross-sectional survey. Setting: Ambulatory examination centers. Patients: Three thousand six hundred twelve adults (522 Asian American) aged 20 to 69 in the 2011 to 2012 National Health and Examination Survey with pure-tone audiometry. Main Outcome Measure(s): Percentage with hearing loss, undertaking a hearing test before the study, and hearing aid use. Hearing loss was defined as better hearing ear speec...
Source: Otology and Neurotology - January 9, 2018 Category: ENT & OMF Tags: Sensorineural Hearing Loss and Tinnitus Source Type: research

Relationship Between the Extent of Endolymphatic Hydrops and the Severity and Fluctuation of Audiovestibular Symptoms in Patients With Menière's Disease and MRI Evidence of Hydrops
Conclusion: The ELH was progressive in the long-term course of the disease in this large population of definite MD patients, but short-term and middle-term fluctuations of the symptom severity did not involve measurable variations of the ELH. Furthermore, the symptom severity did not decrease with increasing disease duration. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 9, 2018 Category: ENT & OMF Tags: Vestibular Disorders Source Type: research

Attenuation of noise-induced hyperactivity in the dorsal cochlear nucleus by pre-treatment with MK-801.
In this study, we examined the effect of administering an NMDA receptor blocker on the induction of hyperactivity in the dorsal cochlear nucleus (DCN) following intense sound exposure. Our prediction was that if hyperactivity induced by intense sound exposure is dependent on NMDA receptors, then blocking these receptors by administering an NMDA receptor antagonist just before animals are exposed to intense sound should reduce the degree of hyperactivity that subsequently emerges. We compared the levels of hyperactivity that develop in the DCN after intense sound exposure to activity recorded in control animals that were no...
Source: Brain Research - January 9, 2018 Category: Neurology Authors: Criddle MW, Godfrey DA, Kaltenbach JA Tags: Brain Res Source Type: research

Effect of transcranial direct current stimulation on short-term and long-term treatment of chronic tinnitus
Conclusion In conclusion, anodal stimulation was more effective than the cathodal and control stimulation in reducing the intensity of tinnitus in the short term. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - January 7, 2018 Category: Endocrinology Source Type: research

A daily blast of sound and electrical pulses may tame tinnitus
A new technique to tackle the phantom noises of tinnitus brought total relief for some patients and eased symptoms in half those who tried it (Source: New Scientist - Health)
Source: New Scientist - Health - January 5, 2018 Category: Consumer Health News Source Type: research

Degree of tinnitus improvement with stapes surgery – a systematic review
Conclusion We conclude that stapes surgery is quite effective for the treatment of tinnitus (average improvement is 85.52%), and hearing loss (average improvement is 93%). When deciding about the surgical indication in patients with otosclerosis, the presence and level tinnitus should be considered as well as the level of hearing. (Source: Brazilian Journal of Otorhinolaryngology)
Source: Brazilian Journal of Otorhinolaryngology - January 5, 2018 Category: ENT & OMF Source Type: research

Inner ear involvement in fabry disease: Clinical and audiometric evaluation of a large cohort of patients followed in a reference centre.
CONCLUSIONS: In FD, hearing loss is common and age-matched hearing thresholds by frequency are worse than in the general population. Hearing loss was associated to the presence of acroparesthesias and higher values of microalbuminuria. Hearing loss stabilized in patients under ERT. A careful cochleo-vestibular evaluation should be part of the clinical assessment of FD. PMID: 29307789 [PubMed - as supplied by publisher] (Source: European Journal of Medical Genetics)
Source: European Journal of Medical Genetics - January 4, 2018 Category: Genetics & Stem Cells Authors: Rodrigues J, Azevedo O, Sousa N, Cunha D, Mexedo A, Fonseca R Tags: Eur J Med Genet Source Type: research

A daily blast of sound and electrical pulses may tame tinnitus
A new technique to tackle the phantom noises of tinnitus brought total relief for some patients and eased symptoms in half those who tried it (Source: New Scientist - Health)
Source: New Scientist - Health - January 3, 2018 Category: Consumer Health News Source Type: research

Effect of Cochlear Implantation on Quality of Life in Adults with Unilateral Hearing Loss
Conclusions: Cochlear implantation in cases of substantial UHL may offer significant improvements in quality of life. Quality of life measures revealed a reduction in perceived tinnitus severity and subjective improvements in speech perception in noise, spatial hearing, and listening effort. While self-report of difficulties were lower for the UHL cohort than the conventional CI and EAS cohorts, subjects in all 3 groups reported an improvement in quality of life with CI use.Audiol Neurotol 2017;22:259-271 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - January 3, 2018 Category: Audiology Source Type: research

Prevalence of tinnitus according to temporomanibular joint disorders and dental pain: the Korean National Population ‐based Study
Summary Some studies have reported that temporomandibular joint disorder (TMD) is related to tinnitus. However, there is no study of the relationship and prevalence of dental pain and tinnitus. We evaluated the associations between the prevalence of tinnitus and TMD and dental pain by analyzing the Korean national health survey. We analyzed total 11,745 participants. Presence of tinnitus, TMD symptoms, and dental pain were surveyed by self‐assessment questionnaires from the all participants. Multivariable regression analysis was applied to acquire odds ratios (OR) and 95% confidence intervals (CI). The prevalence of tinn...
Source: Journal of Oral Rehabilitation - January 3, 2018 Category: Dentistry Authors: Y.H. Kim, Y. G Park, K. D Han, D Vu, K. H Cho, S. Y. Lee Tags: Original Article Source Type: research

[Research Articles] Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans
The dorsal cochlear nucleus is the first site of multisensory convergence in mammalian auditory pathways. Principal output neurons, the fusiform cells, integrate auditory nerve inputs from the cochlea with somatosensory inputs from the head and neck. In previous work, we developed a guinea pig model of tinnitus induced by noise exposure and showed that the fusiform cells in these animals exhibited increased spontaneous activity and cross-unit synchrony, which are physiological correlates of tinnitus. We delivered repeated bimodal auditory-somatosensory stimulation to the dorsal cochlear nucleus of guinea pigs with tinnitus...
Source: Science Translational Medicine - January 3, 2018 Category: Biomedical Science Authors: Marks, K. L., Martel, D. T., Wu, C., Basura, G. J., Roberts, L. E., Schvartz-Leyzac, K. C., Shore, S. E. Tags: Research Articles Source Type: research

Effects of Acoustic Environment on Tinnitus Behavior in Sound-Exposed Rats
AbstractLaboratory studies often rely on a damaging sound exposure to induce tinnitus in animal models. Because the time course and ultimate success of the induction process is not known in advance, it is not unusual to maintain sound-exposed animals for months while they are periodically assessed for behavioral indications of the disorder. To demonstrate the importance of acoustic environment during this period of behavioral screening, sound-exposed rats were tested for tinnitus while housed under quiet or constant noise conditions. More than half of the quiet-housed rats developed behavioral indications of the disorder. ...
Source: JARO - Journal of the Association for Research in Otolaryngology - January 2, 2018 Category: ENT & OMF Source Type: research

Auditory Related Resting State fMRI Functional Connectivity in Tinnitus Patients: Tinnitus Diagnosis Performance
Conclusions: The associations between auditory-related networks are weakened in tinnitus patients, even if they have normal hearing. It is possible that rs-fMRI can be a tool for objective examination of tinnitus, by focusing the auditory-related areas. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 1, 2018 Category: ENT & OMF Tags: Audiology Source Type: research

Health Burden and Socioeconomic Disparities From Hearing Loss: A Global Perspective
Objectives/Hypothesis: To characterize the disability-related health burden of hearing loss (HL) at a global level, with a focus on socioeconomic health disparities. Methods: The global burden of HL, as calculated by disability-adjusted life years (DALYs) per 100,000 individuals, was evaluated for 184 countries. Data from 5-year intervals encompassing 1990 to 2015 were organized by human development index (HDI) categorizations as specified by the U.N. Development Program (UNDP). Gini coefficients and concentration indices were used to evaluate global inequality in HL burden over this time period. Results: There was...
Source: Otology and Neurotology - January 1, 2018 Category: ENT & OMF Tags: Sensorineural Hearing Loss and Tinnitus Source Type: research

Mobile Hearing Testing Applications and the Diagnosis of Sudden Sensorineural Hearing Loss: A Cautionary Tale
Conclusion: While mobile hearing testing apps offer improved access to hearing screening in resource-limited settings, caution must be exercised when interpreting data and making clinical decisions based upon results. The role of professional audiologists remains critical. Further testing and validation of specific apps is required. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 1, 2018 Category: ENT & OMF Tags: Sensorineural Hearing Loss and Tinnitus Source Type: research

Stress and Unusual Events Exacerbate Symptoms in Menière's Disease: A Longitudinal Study
Conclusion: This study provides the strongest evidence to date that stress and unusual events are associated with attacks and symptom exacerbation in MD. Improving our understanding of stress and unusual events as triggers in Menière's may reduce the uncertainty associated with this condition and lead to improved quality of life for affected individuals. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 1, 2018 Category: ENT & OMF Tags: Vestibular Disorders Source Type: research

Hearing Outcomes After Stereotactic Radiosurgery for Jugular Paraganglioma
Conclusion: The short- and intermediate-term risk of progression to nonserviceable hearing following SRS for JP is low. Data regarding the impact of cochlear dose from the vestibular schwannoma literature should not be freely applied to JP, since the impact of SRS parameters on hearing preservation seems to be less significant. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 1, 2018 Category: ENT & OMF Tags: Tumors of the Ear and Cranial Base Source Type: research