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Steroid intracochlear distribution differs by administration method: Systemic versus intratympanic injection
ConclusionWe thus describe differences in cochlear steroid distributions after systemic and IT injections. This finding could help our understanding of the pharmacokinetics of steroids in the cochlea. Level of EvidenceNA. Laryngoscope, 2017 (Source: The Laryngoscope)
Source: The Laryngoscope - February 28, 2017 Category: ENT & OMF Authors: Jong Joo Lee, Jeong Hun Jang, Oak ‐Sung Choo, Hye Jin Lim, Yun‐Hoon Choung Tags: Otology/Neurotology Source Type: research

Psychological Therapy for People with Tinnitus: A Scoping Review of Treatment Components
Conclusions: Scoping review methodology does not attempt to appraise the quality of evidence or synthesize the included records. Further research should therefore determine the relative importance of these different components of psychological therapies from the perspective of the patient and the clinician. (Source: Ear and Hearing)
Source: Ear and Hearing - February 23, 2017 Category: Audiology Tags: Reviews Source Type: research

Evaluating the Precision of Auditory Sensory Memory as an Index of Intrusion in Tinnitus
Conclusions: Changes in the variability of auditory short-term memory may provide a novel means of quantifying the level of intrusion associated with the tinnitus percept during listening. (Source: Ear and Hearing)
Source: Ear and Hearing - February 23, 2017 Category: Audiology Tags: Brief Report Source Type: research

The role of questioning environment, personality traits, depressive and anxiety symptoms in tinnitus severity perception
This study investigated to what extent traits (personality), states (depressive and anxiety symptoms), sociodemographic factors and questioning environment influence tinnitus severity perception and how they interplay. Data were obtained from 212 subjects in a survey that was undertaken in 2016 at Vilnius University hospital and via internet. Measures included the Tinnitus Handicap Inventory (THI), Visual Analogue Scale (VAS), Hospital Anxiety and Depression Scale (HADS), Big Five Personality Dimensions Scale and sociodemographic questions. A series of stepwise forward and multiple regression analyses were undertaken to di...
Source: Psychiatric Quarterly - February 22, 2017 Category: Psychiatry Source Type: research

Clinical effect of intratympanic dexamethasone injection in acute unilateral tinnitus: A prospective, placebo ‐controlled, multicenter study
ConclusionThe results indicate that ITDI might not be more effective than ITNI for the treatment of acute unilateral tinnitus. Therefore, ITDI should not be considered as the main treatment for patients presenting with acute tinnitus as the primary symptom. Level of Evidence1b. Laryngoscope, 2017 (Source: The Laryngoscope)
Source: The Laryngoscope - February 21, 2017 Category: ENT & OMF Authors: Hyun ‐Jin Lee, Min‐Beom Kim, Shin‐Young Yoo, Shi Nae Park, Eui‐Cheol Nam, In Seok Moon, Ho‐Ki Lee Tags: Otology/Neurotology Source Type: research

Clinical Validation of a New Tinnitus Assessment Technology
Sylvie H ébert, Philippe Fournier (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 21, 2017 Category: Neurology Source Type: research

Different Patterns of Hearing Loss among Tinnitus Patients: A Latent Class Analysis of a Large Sample
Berthold Langguth, Michael Landgrebe, Winfried Schlee, Martin Schecklmann, Veronika Vielsmeier, Thomas Steffens, Susanne Staudinger, Hannah Frick, Ulrich Frick (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 20, 2017 Category: Neurology Source Type: research

Hearing-Related Health Among Adult American Indians From a Pacific Northwest Tribe
Conclusions Increasing age and significant noise exposure were associated with hearing loss in this tribe. Tinnitus was associated with significant noise exposure and history of otitis media, even after age adjustment. Public health efforts are needed to improve hearing-related health in this tribe through messages about noise exposure and use of hearing protection. (Source: American Journal of Preventive Medicine)
Source: American Journal of Preventive Medicine - February 15, 2017 Category: Global & Universal Source Type: research

Program Sustainability: Hearing Loss and Tinnitus Prevention in American Indian Communities
Conclusions Critical factors that led to self-sustaining programs included approval of community leaders and engagement of community members in the design, administration, and evaluation of the effort; use of a well-developed, evidence-based intervention; and high-level training of local participants who could confidently and effectively continue delivering the program following a gradual transition to independence. (Source: American Journal of Preventive Medicine)
Source: American Journal of Preventive Medicine - February 15, 2017 Category: Global & Universal Source Type: research

Epidural cortical stimulation for the treatment of chronic resistant tinnitus
Introduction: Tinnitus is a distressing symptom affecting 15% of the adult population for whom no satisfactory treatment exists. It is associated with pathological neural activity in the central auditory system, possibly resulting from suboptimal or maladaptive response to a peripheral lesion. Although the underlying mechanisms are not completely understood, it can be considered as an auditory phantom phenomenon similar to deafferentation pain for the somatosensory system. For this reason, a few studies evaluated the role of epidural cortical stimulation (ECS) in the treatment of tinnitus, with mixed results. (Source: BRAI...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: A. Balossier, R. Carron, J. R égis Source Type: research

Saturation of long-term potentiation in the dorsal cochlear nucleus and its pharmacological reversal in an experimental model of tinnitus.
Abstract Animal models have demonstrated that tinnitus is a pathology of dysfunctional excitability in the central auditory system, in particular in the dorsal cochlear nucleus (DCN) of the brainstem. We used a murine model and studied whether acoustic over-exposure leading to hearing loss and tinnitus, affects long-term potentiation (LTP) at DCN multisensory synapses. Whole cell and field potential recordings were used to study the effects on release probability and synaptic plasticity, respectively in brainstem slices. Shifts in hearing threshold were quantified by auditory brainstem recordings, and gap-induced ...
Source: Experimental Neurology - February 14, 2017 Category: Neurology Authors: Tagoe T, Deeping D, Hamann M Tags: Exp Neurol Source Type: research

Endoscopic Management of Middle Ear Paragangliomas: A Case Series
Conclusions: Endoscopic management of middle ear paraganglioma is safe, feasible, and effective. (Source: Otology and Neurotology)
Source: Otology and Neurotology - February 14, 2017 Category: ENT & OMF Tags: Tumors of the Ear and Cranial Base Source Type: research

Role of preoperative air-bone gap in tinnitus outcome after tympanoplasty for chronic otitis media with tinnitus
Publication date: Available online 14 February 2017 Source:Brazilian Journal of Otorhinolaryngology Author(s): Hong Chan Kim, Chul Ho Jang, Young Yoon Kim, Jong Yuap Seong, Sung Hoon Kang, Yong Beom Cho Introduction Previous reports indicated that middle ear surgery might partially improve tinnitus after surgery. However, until now, no influencing factor has been determined for tinnitus outcome after middle ear surgery. Objective The purpose of this study was to investigate the association between preoperative air-bone gap (ABG) and tinnitus outcome after tympanoplasty type I. Methods Seventy-five patients with tinnitus w...
Source: Brazilian Journal of Otorhinolaryngology - February 13, 2017 Category: ENT & OMF Source Type: research

[Vestibular paroxysmia and paroxysmal tinnitus].
g R PMID: 28197658 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - February 13, 2017 Category: Neurology Authors: Urban PP, Brüning R Tags: Nervenarzt Source Type: research

Acoustic Coordinated Reset Neuromodulation: A Systematic Review of a Novel Therapy for Tinnitus
Marie Wegger, Therese Ovesen, Dalia Gustaityte Larsen (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 13, 2017 Category: Neurology Source Type: research

Tinnitus – Klinik und Therapie
Laryngo-Rhino-Otol 2017; 96: 47-59 DOI: 10.1055/s-0042-119419Tinnitus ist ein Phantomgeräusch, das ein Symptom verschiedener Störungen sein kann, z. B. durch Hörverlust, kardiovaskuläre oder neurologische Erkrankungen, Diabetes oder Tumoren. Bei dekompensiertem Tinnitus leiden die Patienten aufgrund ihrer Unfähigkeit, die auditive Aufmerksamkeit vom Tinnitus-Ton abzulenken, an Schlaflosigkeit, Konzentrationsproblemen und anderen psychologischen Störungen. In extremen Fällen kann es zu Symptomen einer manifesten Depression kommen. Der auditorische Charakter des Tinnitus veranlasst d...
Source: Laryngo- Rhino- Otologie - February 12, 2017 Category: ENT & OMF Authors: Mazurek, Birgit Szczepek, Agnieszka J. Br üggemann, Petra Tags: CME-Fortbildung Source Type: research

Long-term ototoxicity in women after cisplatin treatment for ovarian germ cell cancer.
CONCLUSION: Long-term MOGCT survivors treated with CBCT have small but significant reductions in age-adjusted hearing thresholds at 4, 6 and 8kHz versus Controls. Approximately one in four women experienced subjective hearing loss. To avoid overestimation of clinically relevant cisplatin-induced ototoxicity, absolute hearing thresholds should be age-adjusted and compared to an age-matched control group. PMID: 28202195 [PubMed - as supplied by publisher] (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - February 11, 2017 Category: Cancer & Oncology Authors: Skalleberg J, Solheim O, Fosså SD, Småstuen MC, Osnes T, Gundersen PO, Bunne M Tags: Gynecol Oncol Source Type: research

Categorization of tinnitus in view of history and medical discourse.
Authors: PMID: 28169727 [PubMed - in process] (Source: International Journal of Qualitative Studies on Health and Well-being)
Source: International Journal of Qualitative Studies on Health and Well-being - February 11, 2017 Category: Global & Universal Tags: Int J Qual Stud Health Well-being Source Type: research

Learning from tinnitus patients' narratives-A case study in the psychodynamic approach.
Authors: Dauman N, Erlandsson SI Abstract Tinnitus is assumed to be the perception of sound that results exclusively from activity within the nervous system without any external stimulation. Approximately 1-2% of the population regard their tinnitus as a serious threat towards their quality of life. The way the patients describe their suffering varies, sometimes also depending on the interest and insight of the clinician to whom they turn to for help. The lack of insightful narratives of someone who is severely annoyed by the presence of a constant tinnitus sound may lead to limited and biased models of tinnitus su...
Source: International Journal of Qualitative Studies on Health and Well-being - February 11, 2017 Category: Global & Universal Tags: Int J Qual Stud Health Well-being Source Type: research

Pre- and post-operative dizziness, tinnitus, and taste disturbances among cochlear implant recipients.
CONCLUSION: The high prevalence of dizziness, tinnitus and taste disturbances reported by cochlear implant recipients necessitates that assessment of symptoms related to inner ear and chorda tympani damage are included when evaluating operative results. PMID: 28173884 [PubMed - as supplied by publisher] (Source: Journal of Laryngology and Otology)
Source: Journal of Laryngology and Otology - February 9, 2017 Category: ENT & OMF Tags: J Laryngol Otol Source Type: research

Transcranial magnetic stimulation for tinnitus: using the Tinnitus Functional Index to predict benefit in a randomized controlled trial
Identifying characteristics associated with transcranial magnetic stimulation (TMS) benefit would offer insight as to why some individuals experience tinnitus relief following TMS treatment, whereas others do ... (Source: Trials)
Source: Trials - February 9, 2017 Category: Journals (General) Authors: Sarah M. Theodoroff, Susan E. Griest and Robert L. Folmer Source Type: research

Analysis of Audiometric Differences of Patients with and without Tinnitus in a Large Clinical Database
Dominik Gollnast, Konstantin Tziridis, Patrick Krauss, Achim Schilling, Ulrich Hoppe, Holger Schulze (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 8, 2017 Category: Neurology Source Type: research

Abnormal regional activity and functional connectivity in resting-state brain networks associated with etiology confirmed unilateral pulsatile tinnitus in the early stage of disease.
This study was designed to demonstrate the functional network alterations in the patients with pulsatile tinnitus (PT). In this study, we recruited 45 patients with unilateral PT in the early stage of disease (less than 48 months of disease duration) and 45 normal controls. We used regional homogeneity (ReHo) and seed-based FC computational methods to reveal resting-state brain activity features associated with pulsatile tinnitus. Compared with healthy controls, PT patients showed regional abnormalities mainly in the left middle occipital gyrus (MOG), posterior cingulate gyrus (PCC), precuneus and right anterior insula (AI...
Source: Hearing Research - February 6, 2017 Category: Audiology Authors: Lv H, Zhao P, Liu Z, Li R, Zhang L, Wang P, Yan F, Liu L, Wang G, Zeng R, Li T, Dong C, Gong S, Wang Z Tags: Hear Res Source Type: research

Antidiabetic effects of Morus alba fruit polysaccharides on high-fat diet- and streptozotocin-induced type 2 diabetes in rats
Conclusions MFP50 and MFP90 have markedly antihyperglycemic and antihyperlipidemic effects and can clearly relieve diabetes symptoms in the T2DM rat model. The M. alba fruit polysaccharides may potentially be utilized as an effective treatment for T2DM. Further research into the structures of active M. alba fruit polysaccharides and their mechanisms in promoting antidiabetic effects are underway. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - February 5, 2017 Category: Drugs & Pharmacology Source Type: research

High-Resolution fMRI of Auditory Cortical Map Changes in Unilateral Hearing Loss and Tinnitus.
Abstract Animal models of hearing loss and tinnitus observe pathological neural activity in the tonotopic frequency maps of the primary auditory cortex. Here, we applied ultra high-field fMRI at 7 T to test whether human patients with unilateral hearing loss and tinnitus also show altered functional activity in the primary auditory cortex. The high spatial resolution afforded by 7 T imaging allowed tonotopic mapping of primary auditory cortex on an individual subject basis. Eleven patients with unilateral hearing loss and tinnitus were compared to normal-hearing controls. Patients showed an over-represen...
Source: Brain Topography - February 5, 2017 Category: Neuroscience Authors: Ghazaleh N, Zwaag WV, Clarke S, Ville DV, Maire R, Saenz M Tags: Brain Topogr Source Type: research

A 15-Year-Old Girl With Unexplained Intracranial Hypertension
A white, nonobese, 15-year-old girl presented with 1 month of frontal and occipital throbbing headaches, tinnitus, and “whooshing” in the ears. What is your diagnosis? (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - February 2, 2017 Category: Pediatrics Source Type: research

Is CBT for Tinnitus Overemphasized?
No abstract available (Source: The Hearing Journal)
Source: The Hearing Journal - February 1, 2017 Category: Audiology Tags: Journal Club Source Type: research

A comparative study on the effects of systemic manual acupuncture, periauricular electroacupuncture, and digital electroacupuncture to treat tinnitus: A randomized, paralleled, open-labeled exploratory trial
This study evaluated and compared the... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - January 31, 2017 Category: Complementary Medicine Authors: Bong Hyun Kim, Kyuseok Kim and Hae Jeong Nam Source Type: research

Prevalence of hearing loss and tinnitus in Iraq and Afghanistan veterans: A Chronic Effects of Neurotrauma Consortium study.
Abstract The purpose of this study was to describe the prevalence of hearing loss and tinnitus in a cohort of Iraq and Afghanistan veterans (IAV) with common post-deployment conditions, including traumatic brain injury (TBI), post-traumatic stress disorder (PTSD), and other typical post-concussive conditions such as headaches and vertigo/dizziness. This retrospective observational study used data from the national Veterans Health Administration (VA) data repository from fiscal years 2001-2014. Veteran data was included if there were at least three years of VA care, with one or more years of care in 2007 or after. ...
Source: Hearing Research - January 29, 2017 Category: Audiology Authors: Swan AA, Nelson JT, Swiger B, Jaramillo CA, Eapen BC, Packer M, Pugh MJ Tags: Hear Res Source Type: research

Imaging of carotid artery-cochlear dehiscence. A cause of pulsatile tinnitus
This study was conducted on 8 adult patients. The dehiscences ranged between 0.7 and 1.7mm (average 1.04mm). Two male patients showed bilateral dehiscences together with excessive pneumatization of both petrous apices. Six female patients showed only unilateral dehiscences. In the controls, the internal carotid artery to cochlea (ICA/Ch) distance ranged from 0.59mm to 3.1mm and was 1.618mm in average. The dehiscences were more common in female. However when they occur in males, they tend to be bilateral and seems to be predisposed by excessive pneumatization of both petrous apices. (Source: The Egyptian Journal of Radiolog...
Source: The Egyptian Journal of Radiology and Nuclear Medicine - January 28, 2017 Category: Nuclear Medicine Source Type: research

Repetitive Transcranial Magnetic Stimulation for Tinnitus
This Viewpoint discusses evidence of the efficacy of repetitive transcranial magnetic stimulation for treatment of tinnitus and the need for a randomized clinical trial. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - January 26, 2017 Category: ENT & OMF Source Type: research

Simultaneous idiopathic bilateral sudden hearing loss – characteristics and response to treatment
The objective of this study is identify the characteristics and treatment response of simultaneous bilateral sudden hearing loss. Methods This is a case–control study that practised in tertiary care academic centre. 132 patients with sudden hearing loss (SHL) who were treated with systemic steroid and hyperbaric oxygen together were included. 26 patients had bilateral SHL and 106 patients had unilateral SHL. Patients were evaluated with clinical, audiological and radiological examinations and laboratory tests were done. Findings and response to treatment of the patients were compared. Results and conclusion The mean ...
Source: Brazilian Journal of Otorhinolaryngology - January 24, 2017 Category: ENT & OMF Source Type: research

Neurotological findings after electrical injury at the workplace
ConclusionsFrequency and characterization of symptoms following electrical injury are provided. Dizziness is the most common presenting neurotological feature. Loss of consciousness and/or associated head injury do not affect the clinical presentation in this particular population. Level of Evidence2b. Laryngoscope, 2017 (Source: The Laryngoscope)
Source: The Laryngoscope - January 24, 2017 Category: ENT & OMF Authors: Carolina Wuesthoff, Ophir Ilan, John Alexander Rutka Tags: Otology/Neurotology Source Type: research

Resting-State Brain Abnormalities in Chronic Subjective Tinnitus: A Meta-Analysis
Yu-Chen Chen, Fang Wang, Jie Wang, Fan Bo, Wenqing Xia, Jian-Ping Gu, Xindao Yin (Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - January 24, 2017 Category: Neuroscience Source Type: research

Pulsatile Tinnitus: Differential Diagnosis and Radiological Work-Up
AbstractPurpose of ReviewIdentification of the underlying cause of pulsatile tinnitus is important for treatment decision making and for prognosis estimation. For this, an adequate diagnostic imaging strategy is crucial.Recent FindingsBoth CT and MRI can be useful, and in general, these modalities provide complementary diagnostic information. The scanning protocol can be optimized based on the estimated a priori chance for finding specific pathology, or the need to rule out more rare but clinical significant disease. In recent years, dynamic CTA, also referred to as 4D-CTA, has become available as a new technique that enab...
Source: Current Radiology Reports - January 23, 2017 Category: Radiology Source Type: research

Tinnitus distress is linked to enhanced resting ‐state functional connectivity from the limbic system to the auditory cortex
Abstract The phantom sound of tinnitus is believed to be triggered by aberrant neural activity in the central auditory pathway, but since this debilitating condition is often associated with emotional distress and anxiety, these comorbidities likely arise from maladaptive functional connections to limbic structures such as the amygdala and hippocampus. To test this hypothesis, resting‐state functional magnetic resonance imaging (fMRI) was used to identify aberrant effective connectivity of the amygdala and hippocampus in tinnitus patients and to determine the relationship with tinnitus characteristics. Chronic tinnitus p...
Source: Human Brain Mapping - January 22, 2017 Category: Neurology Authors: Yu ‐Chen Chen, Wenqing Xia, Huiyou Chen, Yuan Feng, Jin‐Jing Xu, Jian‐Ping Gu, Richard Salvi, Xindao Yin Tags: Research Article Source Type: research

Pulsatile tinnitus and carotid artery dissection
Carotid artery dissection is an uncommon entity associated with head and neck pain, partial Horner ’s syndrome, amaurosis fugax, and brain ischemia, which may all occur in isolation or in combination. Herein, we report a rare case of cervical artery dissection in which pulsatile tinnitus was the only reported symptom. A 38-years-old man attended our hospital with a 4-days history of left side p ulsatile tinnitus which began after stumbling. He had no other symptom. MRA showed luminal stenosis with pseudo lumen of the internal carotid artery. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - January 22, 2017 Category: ENT & OMF Authors: Yuya Shimizu, Masato Yagi Source Type: research

Influence of factors and personal habits on the tinnitus perception
Conclusion: more than half of the subjects had bilateral tinnitus and that most situations surveyed do not cause change in the tinnitus perception to the studied people. It is noteworthy, however, that the presence of ambient noise helps to reduce the feeling of tinnitus annoyance, as well as the silence, the period of night and the anxiety contribute to accentuate it. (Source: Revista CEFAC)
Source: Revista CEFAC - January 19, 2017 Category: Speech Therapy Source Type: research

Noise level measurement and its effects on hospital employees based on complaint reports
Conclusion: noise levels are above the recommended levels in different sectors and professionals manifest discomfort and tinnitus before and after their exposure. (Source: Revista CEFAC)
Source: Revista CEFAC - January 19, 2017 Category: Speech Therapy Source Type: research

Cognitive Training for Adults With Bothersome Tinnitus
This randomized clinical trial evaluates the effect of a cognitive training program on bothersome tinnitus in adults. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - January 19, 2017 Category: ENT & OMF Source Type: research

Cochlear implantation for single-sided deafness and tinnitus suppression
Conclusion The present data is in agreement with previously published studies that have shown an improvement in tinnitus following cochlear implantation for the large majority of patients with single-sided deafness. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - January 18, 2017 Category: Endocrinology Source Type: research

A Systems Science Approach to Understanding Polytrauma and Blast-Related Injury: Bayesian Network Model of Data From a Survey of the Florida National Guard
AbstractWe sought to further define the epidemiology of the complex, multiple injuries collectively known as polytrauma/blast-related injury (PT/BRI). Using a systems science approach, we performed Bayesian network modeling to find the most accurate representation of the complex system of PT/BRI and identify key variables for understanding the subsequent effects of blast exposure in a sample of Florida National Guard members (1,443 deployed to Operation Enduring Freedom/Operation Iraqi Freedom and 1,655 not deployed) who completed an online survey during the period from 2009 to 2010. We found that postdeployment symptoms r...
Source: American Journal of Epidemiology - January 18, 2017 Category: Epidemiology Source Type: research

Somatosensory Tinnitus: Correlation between Cranio-Cervico-Mandibular Disorder History and Somatic Modulation
In this study, we included 310 tinnitus patients with normal hearing, no psychiatric comorbidities, and a positive history of TMJ and/or NECK dysfunction and/or a positive modulation of tinnitus to evaluate the characteristics of somatic modulation, investigate the relationship between positive history and positive modulation, and identify factors most strongly associated with somatic modulation. Tinnitus modulation was present in 79.67% of the patients. We found a significant association within the same subjects between a positive history and a positive tinnitus modulation for the same region, mainly for TMJ in unilateral...
Source: Audiology and Neurotology - January 18, 2017 Category: Audiology Source Type: research

The hearing benefit of cochlear implantation for individuals with unilateral hearing loss, but no tinnitus.
CONCLUSION: Cochlear implants improve the hearing abilities of individuals with unilateral hearing loss and no tinnitus. The benefit is no different from that seen in patients with unilateral hearing loss and incapacitating tinnitus. OBJECTIVE: To evaluate hearing outcomes after cochlear implantation in individuals with unilateral hearing loss and no tinnitus and compare them to those obtained in a similar group who had incapacitating tinnitus. METHODS: Six cases who did not experience tinnitus before operation and 15 subjects with pre-operative tinnitus were evaluated with a structured interview, a monosyllabic ...
Source: Acta Oto-Laryngologica - January 17, 2017 Category: ENT & OMF Authors: Skarzynski H, Lorens A, Kruszynska M, Obrycka A, Pastuszak D, Skarzynski PH Tags: Acta Otolaryngol Source Type: research

Selective attentional impairment in chronic tinnitus: Evidence from an event-related potentials study.
CONCLUSION: These results point to a general slowing in early stimulus perception in tinnitus subjects. Moreover, a specific difficulty emerged in attentional switching to unexpected events during an orienting response, probably owing to a dysfunction in the ventral attention network. SIGNIFICANCE: Psychophysiological approach reveals selective attentional impairment and could provide useful data for rehabilitative strategies in chronic tinnitus. PMID: 28160746 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - January 15, 2017 Category: Neurology Authors: Mannarelli D, Pauletti C, Mancini P, Fioretti A, Greco A, De Vincentiis M, Fattapposta F Tags: Clin Neurophysiol Source Type: research

Selective attentional impairment in chronic tinnitus: evidence from an event-related potentials study
Tinnitus is an auditory phantom sensation experienced in the absence of a sound source (Eggermont and Roberts, 2004; Eggermont and Roberts, 2012). Tinnitus is a common symptom that is perceived as chronic by 10-15% of adults (Heller, 2003; Henry et al., 2005), 10-20% of whom report that it interferes with their everyday life (Leske, 1981; Quaranta et al., 1996). It is usually described as a ringing noise, though some patients experience a high-pitched whining, hissing or steady tone. (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - January 13, 2017 Category: Neuroscience Authors: Daniela Mannarelli, Caterina Pauletti, Patrizia Mancini, Alessandra Fioretti, Antonio Greco, Marco De Vincentiis, Francesco Fattapposta Source Type: research

Venous sinus compromise after pre-sigmoid, transpetrosal approach for skull base tumors: A study on the asymptomatic incidence and report of a rare dural arteriovenous fistula as symptomatic manifestation
Publication date: Available online 12 January 2017 Source:Journal of Clinical Neuroscience Author(s): Walter C. Jean, Daniel R. Felbaum, Andrew B. Stemer, Michael Hoa, H. Jeffrey Kim The sigmoid sinus is routinely exposed and manipulated during pre-sigmoid, transpetrosal approaches to the skull base, but there is scant data available on the incidence of venous sinus compromise after surgery. We encountered a dural arteriovenous fistula as a result of sigmoid sinus occlusion and examined the incidence of venous sinus thrombosis or narrowing after transpetrosal surgeries. We performed a retrospective analysis of a series of...
Source: Journal of Clinical Neuroscience - January 12, 2017 Category: Neuroscience Source Type: research

Non-invasive vagus nerve stimulation reduces sympathetic preponderance in patients with tinnitus.
CONCLUSION: Transcutaneous vagal nerve stimulation (tVNS) might offer a targeted, patient-friendly, and low-cost therapeutic tool for tinnitus patients with sympathovagal imbalance. OBJECTIVES: Conventionally, VNS has been performed to treat severe epilepsy and depression with an electrode implanted to the cervical trunk of vagus nerve. This study investigated the acute effects of tVNS on autonomic nervous system (ANS) imbalance, which often occurs in patients with tinnitus-triggered stress. METHODS: This study retrospectively analysed records of 97 patients who had undergone ANS function testing by heart rate va...
Source: Acta Oto-Laryngologica - January 12, 2017 Category: ENT & OMF Authors: Ylikoski J, Lehtimäki J, Pirvola U, Mäkitie A, Aarnisalo A, Hyvärinen P, Ylikoski M Tags: Acta Otolaryngol Source Type: research

Ruxolitinib for symptom control in patients with chronic lymphocytic leukaemia: a single-group, phase 2 trial
Publication date: Available online 12 January 2017 Source:The Lancet Haematology Author(s): Preetesh Jain, Michael Keating, Sarah Renner, Charles Cleeland, Huang Xuelin, Graciela Nogueras Gonzalez, David Harris, Ping Li, Zhiming Liu, Ivo Veletic, Uri Rozovski, Nitin Jain, Phillip Thompson, Prithviraj Bose, Courtney DiNardo, Alessandra Ferrajoli, Susan O'Brien, Jan Burger, William Wierda, Srdan Verstovsek, Hagop Kantarjian, Zeev Estrov Background Disease-related symptoms impair the quality of life of patients with chronic lymphocytic leukaemia (CLL) who do not require systemic therapy. Available therapies are not specifica...
Source: The Lancet Haematology - January 11, 2017 Category: Hematology Source Type: research

[Idiopathic intracranial hypertension].
f A Abstract This review describes the clinical findings as well as thes diagnostic and therapeutic options for idiopathic intracranial hypertension (pseudotumor cerebri). Furthermore, the pathophysiological concepts are discussed. Idiopathic intracranial hypertension is characterized by signs and symptoms of raised intracranial pressure with no established pathogenesis. Common symptoms include headaches, visual loss and pulsatile tinnitus. Treatment has two major goals: the alleviation of headaches and the preservation of vision. Weight loss and acetazolamide are the cornerstones in the treatment of the disorder....
Source: Der Nervenarzt - January 11, 2017 Category: Neurology Authors: Bäuerle J, Egger K, Harloff A Tags: Nervenarzt Source Type: research