Concentration ‐Response Relationship of Hearing Impairment Caused by Quinine and Salicylate: Pharmacological Similarities but different molecular mechanisms
This article is protected by copyright. All rights reserved. (Source: Basic and Clinical Pharmacology and Toxicology)
Source: Basic and Clinical Pharmacology and Toxicology - July 10, 2016 Category: Drugs & Pharmacology Authors: Gunnar Alvan, Erik Berninger, Lars L. Gustafsson, Kjell K. Karlsson, Gilles Paintaud, Monique Wakelkamp Tags: Mini ‐Review Source Type: research

Possible Familial Presentation in Two Siblings with Carotid Fibromuscular Dysplasia.
Authors: Topal H, Lemmens R, Fourneau I Abstract Fibromuscular dysplasia (FMD) is a nonatherosclerotic, noninflammatory vascular disease which can affect the cervical, renal and visceral arteries. Here we report on two sisters diagnosed with carotid FMD at the same age, presenting with similar symptoms of pulsating tinnitus. The familial presentation of this rare disorder attracted our attention and was suggestive of a genetic etiology. Conservative treatment with aspirin was initiated. Carotid FMD is a rare disorder of which the exact pathophysiology is not known. A review of the literature on the clinical present...
Source: Acta Chirurgica Belgica - July 10, 2016 Category: Surgery Tags: Acta Chir Belg Source Type: research

Diazepam reduces excitability of amygdala and further influences auditory cortex following sodium salicylate treatment in rats.
CONCLUSION: Diazepam can reduce the excitability of lateral amygdala and eventually suppress the excitability of the auditory cortex in rats following salicylate treatment, indicating the regulating effect of lateral amygdala to the auditory cortex in the tinnitus procedure. OBJECTIVE: To study the spontaneous firing rates (SFR) of the auditory cortex and lateral amygdala regulated by diazepam in the tinnitus rat model induced by sodium salicylate. MATERIALS AND METHODS: This study first created a tinnitus rat modal induced by sodium salicylate, and recorded SFR of both auditory cortex and lateral amygdala. Then ...
Source: Acta Oto-Laryngologica - July 7, 2016 Category: ENT & OMF Authors: Song Y, Liu J, Ma F, Mao L Tags: Acta Otolaryngol Source Type: research

Anxiety and depression, personality traits relevant to tinnitus: A scoping review
10.1080/14992027.2016.1198966Mithila Durai (Source: International Journal of Audiology)
Source: International Journal of Audiology - July 6, 2016 Category: Audiology Authors: Mithila DuraiGrant Searchfield Source Type: research

Contemporary Neuroradiographic Assessment of the Cochleo-Carotid Partition
Purpose: The cochleo-carotid partition (CCP) describes the intimate anatomic relationship between the petrous carotid artery and the cochlear basal turn. This partition bears significant surgical and unique clinical relevance. The purpose of this paper is to radiographically assess the CCP and discuss its clinical implications. Methods: A total of 155 consecutive fine-cut temporal bone CT scans were retrospectively reviewed, and study scans were digitally analyzed in both axial and coronal views. The shortest distance between the petrous carotid canal and the cochlear basal turn was measured. Results: In all, 310 temporal ...
Source: ORL - July 6, 2016 Category: ENT & OMF Source Type: research

Dietary Supplement Comprised of β-Carotene, Vitamin C, Vitamin E, and Magnesium: Failure to Prevent Music-Induced Temporary Threshold Shift
This study examined potential prevention of music-induced temporary threshold shift (TTS) in normal-hearing participants. A dietary supplement composed of β-carotene, vitamins C and E, and magnesium was assessed using a randomized, placebo-controlled, double-blind study design. Dosing began 3 days prior to the music exposure with the final dose consumed approximately 30-min pre-exposure. Post-exposure TTS was measured, with no significant difference as a function of treatment. Distortion product otoacoustic emission amplitudes were suppressed after music exposure in both groups, with no significant difference as a fun...
Source: Audiology and Neurotology Extra - July 4, 2016 Category: Audiology Source Type: research

Suicidal Ideation Among Patients with Chronic Tinnitus
No abstract available (Source: The Hearing Journal)
Source: The Hearing Journal - July 1, 2016 Category: Audiology Tags: Original Research Source Type: research

Can Platelet Indices Be New Biomarkers for Subjective Tinnitus?
In this study, the authors investigated whether there was a relationship between platelet indices and subjective tinnitus. Methods: In this retrospective study, the authors evaluated platelet indices in subjective tinnitus patients. One hundred patients with subjective tinnitus and 100 healthy, age and sex-matched subjects were enrolled to the study. Audiometer and laboratory results were recorded. Comparative multivariate analyses between indicator factors and hearing outcomes were conducted. Results: Mean platelet volume is significantly lower in subjective tinnitus group (P  (Source: Journal of Craniofacial Surgery)
Source: Journal of Craniofacial Surgery - July 1, 2016 Category: Surgery Tags: Brief Clinical Studies Source Type: research

Position statement: Harmful effects of environmental noise exposures
The American Academy of Nursing promotes the reduction of environmental noise, which is defined as unwanted or disturbing sound (EPA, n.d.). Sources of this noise include household equipment, recreational activities, concerts, roads, railways, airports, and industrial sites. Noise is more than an annoyance; it is a public health hazard, having a significant impact on the health of our nation and its economic well-being. It has been well documented that noise exposure contributes to hearing loss, tinnitus, heart disease, stroke, anxiety, stress, depression, learning difficulties, job performance, sleep disorders, and reduce...
Source: Nursing Outlook - June 30, 2016 Category: Nursing Authors: Sally Lechlitner Lusk, Marjorie McCullagh, Victoria Vaughan Dickson, Jiayun Xu Tags: Article Source Type: research

The impact of the cochlear –carotid interval on tinnitus perception
Conclusion The strong negative correlation of CCI with tinnitus-related distress and accompanying sensorineural hearing loss predominantly at high frequencies suggests that further studies on patients with tinnitus that focus on this small area may help to improve the knowledge of tinnitus pathophysiology. (Source: Surgical and Radiologic Anatomy)
Source: Surgical and Radiologic Anatomy - June 30, 2016 Category: Anatomy Source Type: research

Position statement: Harmful effects of environmental noise exposures
The American Academy of Nursing promotes the reduction of environmental noise, which is defined as unwanted or disturbing sound (EPA, n.d.). Sources of this noise include household equipment, recreational activities, concerts, roads, railways, airports, and industrial sites. Noise is more than an annoyance; it is a public health hazard, having a significant impact on the health of our nation and its economic well-being. It has been well documented that noise exposure contributes to hearing loss, tinnitus, heart disease, stroke, anxiety, stress, depression, learning difficulties, job performance, sleep disorders, and reduce...
Source: Nursing Outlook - June 30, 2016 Category: Nursing Authors: Sally Lechlitner Lusk, Marjorie McCullagh, Victoria Vaughan Dickson, Jiayun Xu Tags: Article Source Type: research

Characterization of tinnitus in different age groups: A retrospective review.
CONCLUSIONS: Chronic tinnitus in older adults is subjectively louder, more annoying, and more distressing than that found in younger patients. We recommend considering age in the patient management plan. PMID: 27569409 [PubMed - in process] (Source: Noise and Health)
Source: Noise and Health - June 30, 2016 Category: Audiology Authors: Al-Swiahb J, Park SN Tags: Noise Health Source Type: research

Characteristics of hyperacusis in the general population.
The objectives of the present study were to investigate individuals in the general population with hyperacusis regarding demographics, lifestyle, perceived general health and hearing ability, hyperacusis-specific characteristics and behavior, and comorbidity. Using data from a large-scale population-based questionnaire study, we investigated individuals with physician-diagnosed (n = 66) and self-reported (n = 313) hyperacusis in comparison to individuals without hyperacusis (n = 2995). High age, female sex, and high education were associated with hyperacusis, and that trying to avo...
Source: Noise and Health - June 30, 2016 Category: Audiology Authors: Paulin J, Andersson L, Nordin S Tags: Noise Health Source Type: research

Impact of Multiple Factors on the Degree of Tinnitus Distress
Petra Brüggemann, Agnieszka J. Szczepek, Matthias Rose, Laurence McKenna, Heidi Olze, Birgit Mazurek (Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - June 28, 2016 Category: Neuroscience Source Type: research

Association between the extent of sigmoid sinus dehiscence and an occurrence of pulsatile tinnitus: a retrospective imaging study
To assess the extent of sigmoid sinus dehiscence (SSD) on high-resolution computed tomography venography (HRCTV) or high-resolution computed tomography (HRCT) images in pulsatile tinnitus (PT) and non-PT groups to determine whether there is an association between the extent of SSD and occurrence of PT. (Source: Clinical Radiology)
Source: Clinical Radiology - June 28, 2016 Category: Radiology Authors: C. Dong, P. Zhao, Z. Liu, W. Xu, H. Lv, S. Pang, Z. Wang Source Type: research

Cochlear implantation for single‐sided deafness: A multicenter study
ConclusionPreliminary results suggest that speech recognition in a singly deafened ear is significantly improved after cochlear implantation, although speech recognition in noise measured in the bilateral condition remains the same at 6‐months postactivation. Level of Evidence4. Laryngoscope, 2016 (Source: The Laryngoscope)
Source: The Laryngoscope - June 26, 2016 Category: ENT & OMF Authors: Douglas P. Sladen, Christopher D. Frisch, Matthew L. Carlson, Colin L.W. Driscoll, Jennifer H. Torres, Daniel M. Zeitler Tags: Otology/Neurotology Source Type: research

Paediatric tinnitus: The unmet clinical need
10.1080/14992027.2016.1190467Rachel Humphriss (Source: International Journal of Audiology)
Source: International Journal of Audiology - June 26, 2016 Category: Audiology Authors: Rachel HumphrissAmanda HallDavid Baguley Source Type: research

Cochlear implantation for single ‐sided deafness: A multicenter study
ConclusionPreliminary results suggest that speech recognition in a singly deafened ear is significantly improved after cochlear implantation, although speech recognition in noise measured in the bilateral condition remains the same at 6‐months postactivation. Level of Evidence4. Laryngoscope, 2016 (Source: The Laryngoscope)
Source: The Laryngoscope - June 26, 2016 Category: ENT & OMF Authors: Douglas P. Sladen, Christopher D. Frisch, Matthew L. Carlson, Colin L.W. Driscoll, Jennifer H. Torres, Daniel M. Zeitler Tags: Otology/Neurotology Source Type: research

Perilymphatic fistula after underwater diving: a series of 11 cases.
CONCLUSION: The diagnosis of perilymphatic fistula is based on clinical assessments and various laboratory findings. When there was strong evidence of this condition, surgery yielded excellent functional outcomes in all patients treated early. PMID: 27334993 [PubMed - in process] (Source: Diving and Hyperbaric Medicine)
Source: Diving and Hyperbaric Medicine - June 25, 2016 Category: Sports Medicine Tags: Diving Hyperb Med Source Type: research

Comparative observational study on the clinical presentation, intracranial volume measurements, and intracranial pressure scores in patients with either Chiari malformation Type I or idiopathic intracranial hypertension.
Abstract OBJECTIVE Several lines of evidence suggest common pathophysiological mechanisms in Chiari malformation Type I (CMI) and idiopathic intracranial hypertension (IIH). It has been hypothesized that tonsillar ectopy, a typical finding in CMI, is the result of elevated intracranial pressure (ICP) combined with a developmentally small posterior cranial fossa (PCF). To explore this hypothesis, the authors specifically investigated whether ICP is comparable in CMI and IIH and whether intracranial volumes (ICVs) are different in patients with CMI and IIH, which could explain the tonsillar ectopy in CMI. The author...
Source: Journal of Neurosurgery - June 23, 2016 Category: Neurosurgery Authors: Frič R, Eide PK Tags: J Neurosurg Source Type: research

Hearing thresholds, tinnitus, and headphone listening habits in nine-year-old children
10.1080/14992027.2016.1190871Sara Båsjö (Source: International Journal of Audiology)
Source: International Journal of Audiology - June 21, 2016 Category: Audiology Authors: Sara BåsjöClaes MöllerStephen WidénGöran JutengrenKim Kähäri Source Type: research

Mid-term Outcomes of Anterior Cervical Fusion for Cervical Spondylosis With Sympathetic Symptoms
Study Design: Prospective study. Objective: The purpose of this study is to elucidate mid-term outcomes of anterior cervical fusion for cervical spondylosis with sympathetic symptoms (CSSS). Summary of Background Date: The terminology, pathogenesis, diagnosis, and treatment of CSSS remain controversial. Surgical treatment of CSSS has been rarely reported. This is the first prospective study to evaluate the mid-term outcome of surgical treatment of CSSS. Methods: Thirty-one patients who were diagnosed with CSSS in 2006 were evaluated prospectively. All patients were assigned to undergo anterior cervical fusion with poste...
Source: Journal of Spinal Disorders and Techniques - June 21, 2016 Category: Surgery Tags: Primary Research Source Type: research

Quality of Life and Hearing Eight Years After Sudden Sensorineural Hearing Loss
ConclusionIdiopathic sudden sensorineural hearing loss that failed to recover had a negative impact on long‐term QoL and QoH. The hearing deteriorated as a function of age similarly both in the affected and the healthy ear, and there were no differences between the groups. The cumulative recurrence rate for ISSNHL was 3.5%. Level of Evidence4 Laryngoscope, 2016 (Source: The Laryngoscope)
Source: The Laryngoscope - June 20, 2016 Category: ENT & OMF Authors: Kati Härkönen, Ilkka Kivekäs, Markus Rautiainen, Voitto Kotti, Juha‐Pekka Vasama Tags: Otology/Neurotolgoy Source Type: research

Psychological Mediators of Chronic Tinnitus: The Critical Role of Depression
Maintenance of chronic tinnitus has been proposed to result from a vicious cycle of hypervigilance occurring when a phantom sound is associated with anxiety and limbic system overactivity. Depression, obsessive-compulsiveness, illness attitudes and coping strategies are known to impact tinnitus, but their relationship with the vicious cycle is unknown. As such, we aimed to identify psychological mediators of the vicious cycle. We also examined the relationship between coping strategies and any identified mediators to facilitate the translation of our research to treatment settings. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - June 20, 2016 Category: Neurology Authors: Krysta J Trevis, Neil M McLachlan, Sarah J Wilson Tags: Research paper Source Type: research

Treatment of Meniere ’s disease with intratympanic dexamethazone plus high dosage of betahistine
Conclusions Our preliminary results demonstrate that complete and substantial vertigo control is significantly higher in patients treated with a combination of HDBH and ITD. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - June 17, 2016 Category: Endocrinology Source Type: research

Intratympanic dexamethasone in Meniere ’s disease
Conclusion: Intratympanic dexamethasone for Meniere’s disease is very satisfactory if medical treatment fails with good vertigo control and no risk to hearing. (Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences)
Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences - June 17, 2016 Category: ENT & OMF Source Type: research

Intratympanic dexamethasone in Meniere’s disease
Conclusion: Intratympanic dexamethasone for Meniere’s disease is very satisfactory if medical treatment fails with good vertigo control and no risk to hearing. (Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences)
Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences - June 16, 2016 Category: ENT & OMF Source Type: research

Prevalence and associated risk factors of otitis media and its subtypes in South Indian population
Conclusions: The study has revealed that otitis media predominantly affects all age groups and has a serious health concern in cases affected with hearing loss and its associated co-morbidities. (Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences)
Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences - June 16, 2016 Category: ENT & OMF Source Type: research

Tinnitus Screener: Results From the First 100 Participants in an Epidemiology Study.
Conclusions: These results provide preliminary evidence that the Screener may be suitable for quickly determining essential parameters of reported tinnitus. We have since revised the instrument to differentiate acute from chronic tinnitus and to identify occasional tinnitus. We are also obtaining measures that will enable assessment of its test-retest reliability. PMID: 27315442 [PubMed - as supplied by publisher] (Source: American Journal of Audiology)
Source: American Journal of Audiology - June 16, 2016 Category: Audiology Authors: Henry JA, Griest S, Austin D, Helt W, Gordon J, Thielman E, Theodoroff SM, Lewis MS, Blankenship C, Zaugg TL, Carlson K Tags: Am J Audiol Source Type: research

An Investigation of Feasibility and Safety of Bi‐Modal Stimulation for the Treatment of Tinnitus: An Open‐Label Pilot Study
ObjectivesTinnitus is the perception of sound in the absence of an external auditory stimulus. It is widely believed that tinnitus, in patients with associated hearing loss, is a neurological phenomenon primarily affecting the central auditory structures. However, there is growing evidence for the involvement of the somatosensory system in this form of tinnitus. For this reason it has been suggested that the condition may be amenable to bi‐modal stimulation of the auditory and somatosensory systems. We conducted a pilot study to investigate the feasibility and safety of a device that delivers simultaneous auditory and so...
Source: Neuromodulation: Technology at the Neural Interface - June 15, 2016 Category: Biotechnology Authors: Caroline Hamilton, Shona D'Arcy, Barak A. Pearlmutter, Gloria Crispino, Edmund C. Lalor, Brendan J. Conlon Tags: Basic Research Source Type: research

An Investigation of Feasibility and Safety of Bi ‐Modal Stimulation for the Treatment of Tinnitus: An Open‐Label Pilot Study
ObjectivesTinnitus is the perception of sound in the absence of an external auditory stimulus. It is widely believed that tinnitus, in patients with associated hearing loss, is a neurological phenomenon primarily affecting the central auditory structures. However, there is growing evidence for the involvement of the somatosensory system in this form of tinnitus. For this reason it has been suggested that the condition may be amenable to bi‐modal stimulation of the auditory and somatosensory systems. We conducted a pilot study to investigate the feasibility and safety of a device that delivers simultaneous auditory and so...
Source: Neuromodulation: Technology at the Neural Interface - June 15, 2016 Category: Biotechnology Authors: Caroline Hamilton, Shona D'Arcy, Barak A. Pearlmutter, Gloria Crispino, Edmund C. Lalor, Brendan J. Conlon Tags: Basic Research Source Type: research

Absence of skin discoloration after transarterial embolization of a subcutaneous auricular arteriovenous malformation with PHIL.
CONCLUSION: To our knowledge, this is the first case report describing PHIL embolization as a treatment option for superficial arteriovenous malformations without the necessity for subsequent surgery. The white color and rubbery consistency are beneficial characteristics of PHIL in treatment of subcutaneous lesions, especially in cosmetically relevant locations. PMID: 27298010 [PubMed - as supplied by publisher] (Source: Interventional Neuroradiology)
Source: Interventional Neuroradiology - June 15, 2016 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Objectification and Differential Diagnosis of Vascular Pulsatile Tinnitus by Transcanal Sound Recording and Spectrotemporal Analysis: A Preliminary Study
Conclusion: The present diagnostic approach may provide additional information regarding the origins of VPT cases as well as an efficient and objective diagnostic method. Furthermore, this approach may aid in the determination of appropriate imaging modalities, treatment planning, and evaluation of treatment outcomes. (Source: Otology and Neurotology)
Source: Otology and Neurotology - June 15, 2016 Category: ENT & OMF Tags: Research Methodology Source Type: research

Prognostic and Evolutive Factors of Tinnitus Triggered by Sudden Sensorineural Hearing Loss
The objective of the study is to evaluate tinnitus of which onset is concurrent with SSNHL and analyze it as a prognostic factor and its correlation with hearing recovery. Materials and Methods: A prospective cohort study was conducted with 30 patients with SSNHL. Serial audiometry was performed and the Tinnitus Handicap Inventory (THI) was applied at the initial consultation and after treatment. Results: Tinnitus had an incidence of 93.3%, with an initial mean THI of 63.6%. The mean decrease in THI was significant in all scale domains. However, there was no statistically significant difference between the degrees of tin...
Source: Otology and Neurotology - June 15, 2016 Category: ENT & OMF Tags: Sensorineural Hearing Loss & Tinnitus Source Type: research

Characteristics and Spontaneous Recovery of Tinnitus Related to Idiopathic Sudden Sensorineural Hearing Loss
Conclusions: Prognosis for ISSNHL-related tinnitus is relatively poor in case of severe-profound hearing loss and the longer it has persisted. Alleviation or management of tinnitus should be a key therapeutic objective especially in pronounced ISSNHL cases. (Source: Otology and Neurotology)
Source: Otology and Neurotology - June 15, 2016 Category: ENT & OMF Tags: Sensorineural Hearing Loss & Tinnitus Source Type: research

Relationships between tinnitus and the prevalence of anxiety and depression
Objectives/HypothesisQuantify the relationships between tinnitus, and anxiety and depression among adults. Study DesignCross‐sectional analysis of a national health survey. MethodsAdult respondents in the 2007 Integrated Health Interview Series tinnitus module were analyzed. Data for tinnitus symptoms and severity and reported anxiety and depression symptoms were extracted. Associations between tinnitus problems and anxiety, depression, lost workdays, days of alcohol consumption, and mean hours of sleep were assessed. ResultsAmong 21.4 ± 0.69 million adult tinnitus sufferers, 26.1% reported problems with anxiety i...
Source: The Laryngoscope - June 14, 2016 Category: ENT & OMF Authors: Jay M. Bhatt, Neil Bhattacharyya, Harrison W. Lin Tags: Otology/Neurotology Source Type: research

Multiple sclerosis and primary vascular dysregulation (Flammer syndrome)
Conclusions MS patients suffer significantly more often from FS symptoms and signs than controls. The reason for this association between MS and FS and the potential implications of this association still need to be determined. (Source: EPMA Journal)
Source: EPMA Journal - June 14, 2016 Category: Global & Universal Source Type: research

Next generation shape memory prosthesis (NiTiBOND) for stapedotomy: Short‐term results
ConclusionsCompared with the SMart prosthesis, the NiTiBOND prosthesis is a safe prosthesis that achieves at least comparable hearing results and may offer some surgical advantages. Level of Evidence4 Laryngoscope, 2016 (Source: The Laryngoscope)
Source: The Laryngoscope - June 13, 2016 Category: ENT & OMF Authors: J. Douglas Green, John T. McElveen Tags: Otology/Neurotology Source Type: research

Next generation shape memory prosthesis (NiTiBOND) for stapedotomy: Short ‐term results
ConclusionsCompared with the SMart prosthesis, the NiTiBOND prosthesis is a safe prosthesis that achieves at least comparable hearing results and may offer some surgical advantages. Level of Evidence4 Laryngoscope, 127:915–920, 2017 (Source: The Laryngoscope)
Source: The Laryngoscope - June 13, 2016 Category: ENT & OMF Authors: J. Douglas Green, John T. McElveen Tags: Otology/Neurotology Source Type: research

Intraoperative cone-beam computed tomography contributes to avoiding hypoglossal nerve palsy during transvenous embolization for dural arteriovenous fistula of the anterior condylar confluence.
CONCLUSION: An intraoperative cone-beam CT contributed to avoiding hypoglossal nerve palsy by estimating the relationship between the coil mass and the hypoglossal canal during TVE of ACC-DAVF. PMID: 27288404 [PubMed - as supplied by publisher] (Source: Interventional Neuroradiology)
Source: Interventional Neuroradiology - June 12, 2016 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Five Synchronous Paragangliomas of the Head and Neck: A Case Report.
Authors: Yavapolkul D, Jittreetat T Abstract This is a case report of synchronous bilateral carotid body tumor, bilateral jugulotympanic and left subclavian paraganglioma in a 38-year-old man who presented with a history of slow-growing bilateral neck masses for 4 years and a one-month history of right facial palsy, tinnitus, and hearing loss. A discussion of this case is followed by a review of the literature surrounding this rare clinical entity. PMID: 27266239 [PubMed - in process] (Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet)
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - June 10, 2016 Category: Journals (General) Tags: J Med Assoc Thai Source Type: research

Acute Stroke in a Girl with an Absent Radial Pulse
A 13 year-old right-handed girl woke with left-sided tinnitus, left facial burning, slurred speech, and confusion. Past medical history included poorly controlled ulcerative colitis, von Willebrand’s disease type 2, and anemia [hemoglobin 9.2 g/dL; normal 11.2-14.8 g/dL]. Medications included mercaptopurine, mesalamine, and ferrous sulfate. (Source: Pediatric Neurology)
Source: Pediatric Neurology - June 9, 2016 Category: Neurology Authors: Shivani Ghoshal, Richard A. Bronen, Paul L. McCarthy, Salley G. Pels, Lauren A. Beslow Tags: Visual Diagnosis Source Type: research

Acute Stroke in a Girl With an Absent Radial Pulse
This 13-year-old right-handed girl awoke with left tinnitus, left facial burning, slurred speech, and confusion. Her past medical history included poorly controlled ulcerative colitis, von Willebrand disease type 2, and anemia (hemoglobin 9.2  g/dL; normal 11.2 to 14.8 g/dL). Medications included mercaptopurine, mesalamine, and ferrous sulfate. (Source: Pediatric Neurology)
Source: Pediatric Neurology - June 9, 2016 Category: Neurology Authors: Shivani Ghoshal, Richard A. Bronen, Paul L. McCarthy, Salley G. Pels, Lauren A. Beslow Tags: Visual Diagnosis Source Type: research

Interventions for Meniere's disease: protocol for an umbrella systematic review and a network meta-analysis
Introduction The large number of treatment modalities for patients diagnosed with Menière's disease (MD) complicates the selection of the best available treatment as the comparative efficacy of these interventions is not clear. We aim to identify the treatment or treatments with the highest efficacy of current pharmacological and non-pharmacological treatments for MD. Methods and analysis We will identify all available systematic reviews on the treatment of MD. An online database search will be conducted in association with the UK Cochrane Centre, particularly the Ear, Nose and Throat Group. We will screen the syst...
Source: BMJ Open - June 8, 2016 Category: Journals (General) Authors: van Esch, B. F., van der Zaag-Loonen, H. J., Bruintjes, T. D., van Benthem, P. P. G. Tags: Open access, Ear, nose and throat/otolaryngology, Evidence based practice, Medical management, Patient-centred medicine, Qualitative research Protocol Source Type: research

Imaging Manifestations of Neurologic Complications in Anemia
The hallmark signs and symptoms of anemia are directly related to a decrease in oxygen delivery to vital tissues and organs and include pallor, fatigue, lightheadedness, and shortness of breath. Neurologic complications are often nonspecific and can include poor concentration, irritability, faintness, tinnitus, and headache. If undiagnosed or untreated, anemia can progress to cognitive dysfunction, psychosis, encephalopathy, myelopathy, peripheral neuropathy, and more focal syndromes, such as stroke, seizures, chorea, and transverse myelitis. Imaging can play an important role in the early diagnosis and treatment of these ...
Source: Hematology/Oncology Clinics of North America - June 6, 2016 Category: Cancer & Oncology Authors: Ritesh Patel, Shyam Sabat, Sangam Kanekar Source Type: research

Imaging Manifestations of Neurologic Complications in Anemia
Publication date: Available online 7 June 2016 Source:Hematology/Oncology Clinics of North America Author(s): Ritesh Patel, Shyam Sabat, Sangam KanekarTeaser The hallmark signs and symptoms of anemia are directly related to a decrease in oxygen delivery to vital tissues and organs and include pallor, fatigue, lightheadedness, and shortness of breath. Neurologic complications are often nonspecific and can include poor concentration, irritability, faintness, tinnitus, and headache. If undiagnosed or untreated, anemia can progress to cognitive dysfunction, psychosis, encephalopathy, myelopathy, peripheral neuropathy, and...
Source: Hematology Oncology Clinics of North America - June 6, 2016 Category: Hematology Source Type: research

Tinnitus.
PMID: 27270658 [PubMed - in process] (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - June 6, 2016 Category: Internal Medicine Authors: Masson V Tags: Ann Intern Med Source Type: research

Imaging Manifestations of Neurologic Complications in Anemia
The hallmark signs and symptoms of anemia are directly related to a decrease in oxygen delivery to vital tissues and organs and include pallor, fatigue, lightheadedness, and shortness of breath. Neurologic complications are often nonspecific and can include poor concentration, irritability, faintness, tinnitus, and headache. If undiagnosed or untreated, anemia can progress to cognitive dysfunction, psychosis, encephalopathy, myelopathy, peripheral neuropathy, and more focal syndromes, such as stroke, seizures, chorea, and transverse myelitis. Imaging can play an important role in the early diagnosis and treatment of these ...
Source: Hematology/Oncology Clinics of North America - June 6, 2016 Category: Cancer & Oncology Authors: Ritesh Patel, Shyam Sabat, Sangam Kanekar Source Type: research

Prevalence of tinnitus and hyperacusis in children and adolescents: a systematic review
Conclusions Data on prevalence vary considerably according to the study design, study population and the research question posed. The age range of children studied was varied and a marked degree of variation between definitions (tinnitus, hyperacusis) and measures (severity, perception, annoyance) was observed. The lack of consistency among studies indicates the necessity of examining the epidemiology of tinnitus and hyperacusis in children and adolescents with a set of standardised criteria. Trial registration number CRD42014013456. (Source: BMJ Open)
Source: BMJ Open - June 2, 2016 Category: Journals (General) Authors: Rosing, S. N., Schmidt, J. H., Wedderkopp, N., Baguley, D. M. Tags: Open access, Ear, nose and throat/otolaryngology, Epidemiology, Paediatrics Research Source Type: research