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Delayed hyperbaric intervention in life-threatening decompression illness.
We report on a 51-year-old, male rebreather diver who suffered loss of consciousness and cardiovascular collapse within minutes of a 30-metre deep dive at a remote Micronesian dive site. Recompression treatment did not start for six days for reasons to be presented, during which time he remained deeply comatose, cardiovascularly unstable and intubated on ventilator support. Despite this, following aggressive hyperbaric treatment over many days he made a functional recovery. At one year post injury, he is leading a functional life but has not returned to his previous occupation as a diver and suffers from moderately severe ...
Source: Diving and Hyperbaric Medicine - December 15, 2017 Category: Sports Medicine Tags: Diving Hyperb Med Source Type: research

Neural plasticity and its initiating conditions in tinnitus.
CONCLUSION: The latter process may be induced by transient auditory events in normal processing but it persists in tinnitus, driven by phantom signals from the auditory pathway. Several tinnitus therapies attempt to suppress tinnitus through plasticity, but repeated sessions will likely be needed to prevent tinnitus activity from returning owing to deafferentation as its initiating condition. PMID: 29234817 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - December 15, 2017 Category: ENT & OMF Tags: HNO Source Type: research

PTA Stent of Dural Sinuses in Brain DAVF
ConclusionIn cases of type I and II DAVFs associated with sinus stenosis, angioplasty and stenting alone seem to be safe and effective. This treatment probably compresses the venules within the sinus walls, promoting thrombosis of the shunts thus solving the underlying cause of the fistula. (Source: Clinical Neuroradiology)
Source: Clinical Neuroradiology - December 14, 2017 Category: Neurology Source Type: research

Randomized Controlled Trial of a Novel Device for Tinnitus Sound Therapy During Sleep
Conclusions This study offers some support for greater average improvement in reactions to tinnitus with TM or NS devices compared to the BSG device. The TM group, compared to the BSG and NS groups, showed a greater reduction in ratings of tinnitus loudness on the NRS on average.Supplemental Materialhttps://doi.org/10.23641/asha.5545759 (Source: American Journal of Audiology)
Source: American Journal of Audiology - December 12, 2017 Category: Audiology Source Type: research

Factors Associated With Depression in Patients With Tinnitus and Hyperacusis
Conclusion Those involved in the management of patients with tinnitus and/or hyperacusis should use a wide range of instruments to assess the full impact of tinnitus on a patient's life and should be prepared to refer a patient for treatment for depression, especially when the patient has anxiety, hyperacusis, and/or insomnia. (Source: American Journal of Audiology)
Source: American Journal of Audiology - December 12, 2017 Category: Audiology Source Type: research

Quality of life in individuals with tinnitus with and without hearing loss
ABSTRACT Purpose: to evaluate the perception of the level of quality of life in subjects with tinnitus, with and without hearing loss. Methods: a cross-sectional quantitative study. A total of 189 subjects (mean age 53.06 years) divided into four groups. Group 1: subjects with normal auditory thresholds without tinnitus complaint; Group 2: subjects with normal auditory thresholds and tinnitus complaint; Group 3: subjects with sensorineural hearing loss without tinnitus complaint; Group 4: subjects with sensorineural hearing loss and with tinnitus complaint. Levels of quality of life were investigated through the World Heal...
Source: Revista CEFAC - December 11, 2017 Category: Speech-Language Pathology Source Type: research

Quality of life, perception and knowledge of dentists on noise
Conclusion: noise was considered, regardless of gender, harmful to health and associated with perception of musculoskeletal pain. Symptoms and complaints caused by noise have been reported to negatively impact the professional activity of dentists, however, most of them do not adopt preventive measures.RESUMO Objetivo: analisar a percep ção e conhecimento de odontólogos sobre o ruído, sua prevenção e efeitos na saúde e qualidade de vida. Métodos: estudo transversal, realizado com 54 dentistas de ambos os gêneros. Aplicou-se dois questionários: um abordand...
Source: Revista CEFAC - December 11, 2017 Category: Speech-Language Pathology Source Type: research

Intracranial hypertension induced by internal jugular vein stenosis can be resolved by stenting
Background and purposeIdiopathic intracranial hypertension (IIH) is characterized by abnormally elevated intracranial pressure (ICP) without identifiable etiology. Recently, however, a subset of patients with presumed IIH have been found with isolated internal jugular vein (IJV) stenosis in the absence of intracranial abnormalities. MethodsFifteen consecutive patients were screened from 46 patients suspected as IIH and were finally confirmed as isolated IJV stenosis. The stenotic IJV was corrected with stenting when the trans‐stenotic mean pressure gradient (∆MPG) was equal to or higher than 5.44 cmH2O. Dynamic magneti...
Source: European Journal of Neurology - December 7, 2017 Category: Neurology Authors: D. Zhou, R. Meng, X. Zhang, L. Guo, S. Li, W. Wu, J. Duan, H. Song, Y. Ding, X. Ji Tags: Original Article Source Type: research

[Central and peripheral aspects of noise-induced hearing loss].
Authors: Basta D, Gröschel M, Ernst A Abstract Noise is an important socioeconomic problem in industrialized countries. Development of efficient treatment options for the audiological phenomena resulting from noise-induced hearing loss requires in-depth understanding of the underlying damage mechanisms causing peripheral and central nervous changes. Mechanical damage, ischemia and excitotoxicity are mainly responsible for noise-induced cell death and biophysical changes in the cochlea. Auditory synaptopathy is an additional consequence. Besides these cochlear pathologies, noise exposure leads to extensive chan...
Source: HNO - December 6, 2017 Category: ENT & OMF Tags: HNO Source Type: research

Facial palsy after embolization of dural arteriovenous fistula: A case report and literature review.
Conclusion: Although embolization is an effective and safe procedure, complications may occur. Reflux of the embolic agent to the vasa nervorum of the cranial nerve may lead to ischemic neuropathy. Here, we reported a case of embolized DAVF presenting with a postoperative peripheral facial palsy where the two embolized pedicles were branches of the middle meningeal and occipital arteries involved in the vascularization of the extratemporal segment of the facial nerve. We discuss the etiopathogenic, anatomical, and pathophysiological aspects of this complication. PMID: 29204306 [PubMed] (Source: Surgical Neurology International)
Source: Surgical Neurology International - December 6, 2017 Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

Factors Associated With Depression in Patients With Tinnitus and Hyperacusis.
Conclusion: Those involved in the management of patients with tinnitus and/or hyperacusis should use a wide range of instruments to assess the full impact of tinnitus on a patient's life and should be prepared to refer a patient for treatment for depression, especially when the patient has anxiety, hyperacusis, and/or insomnia. PMID: 29209701 [PubMed - as supplied by publisher] (Source: American Journal of Audiology)
Source: American Journal of Audiology - December 6, 2017 Category: Audiology Authors: Aazh H, Moore BCJ Tags: Am J Audiol Source Type: research

Ethnopharmacology, phytochemistry, and pharmacology of Cornus officinalis Sieb. et Zucc
Conclusions In this paper, we reviewed various studies conducted on C. officinalis, especially in areas of its ethnopharmacological use, as well as on its phytochemistry, pharmacology, and modern analytical methods used. Some of the herb’s ethnomedical indications have been confirmed by the herb’s pharmacological effects, such as its hepatic and renal protection and the antidiabetic effects. In particular, the crude extract and its chemical composition have exerted good therapeutic effect in diabetic treatment. C. officinalis entails additional attention on its pharmacological effects and drug development to ex...
Source: Journal of Ethnopharmacology - December 5, 2017 Category: Drugs & Pharmacology Source Type: research

The mediating role of tinnitus perception between hearing impairment and development of psychological problems in male and female tinnitus patients
International Journal of Human Rights in Healthcare,Volume 10, Issue 5, Page 332-343, December 2017. Purpose The purpose of this paper is to investigate the mediating role of psychological problems (stress, anxiety, depression) between hearing impairment (HI) and tinnitus in tinnitus patients. Sample comprised of 110 patients (male, n=70; female, n=40). Design/methodology/approach The purposive sampling technique was used based on correlational design. Two scales, tinnitus handicap inventory developed by Newman et al. (1996), and depression, anxiety and stress scale developed by Lovibond and Lovibond (1995), were employed ...
Source: International Journal of Human Rights in Healthcare - December 4, 2017 Category: International Medicine & Public Health Source Type: research

Clinical Features, Familial History, and Migraine Precursors in Patients With Definite Vestibular Migraine: The VM-Phenotypes Projects.
CONCLUSIONS: Our results may indicate that vestibular symptoms in pediatric patients may act as a predisposing factor to develop vestibular migraine at an earlier age in adulthood. PMID: 29205326 [PubMed - as supplied by publisher] (Source: Headache)
Source: Headache - December 4, 2017 Category: Neurology Authors: Teggi R, Colombo B, Albera R, Asprella Libonati G, Balzanelli C, Batuecas Caletrio A, Casani A, Espinoza-Sanchez JM, Gamba P, Lopez-Escamez JA, Lucisano S, Mandalà M, Neri G, Nuti D, Pecci R, Russo A, Martin-Sanz E, Sanz R, Tedeschi G, Torelli P, Vannucc Tags: Headache Source Type: research

Role of trichloroacetic acid and gelfoam in closure of tympanic membrane perforations
Conclusions: Cautery and patching of tympanic membrane perforation may be considered as the first-line management in the small- to medium-sized perforations before attempting the surgical closure. (Source: Nigerian Journal of Clinical Practice)
Source: Nigerian Journal of Clinical Practice - December 1, 2017 Category: Rural Health Authors: M Singh M Kaur B Singh K Singh A Singh A Kaur Source Type: research

The effect of specially designed and managed occlusal devices on patient symptoms of tinnitus: A cohort study
. (Source: Cranio - Journal of Craniomandibular and Sleep Practice)
Source: Cranio - Journal of Craniomandibular and Sleep Practice - December 1, 2017 Category: Sleep Medicine Authors: L. Parnell Taylor Wayne O. Sletten Thomas D. Dumont Source Type: research

Tinnitus Is Associated with a Higher Risk of Benign Brain Tumors: A Nationwide, Population-Based Secondary Cohort Study of Young and Middle-Aged Adults
Conclusions: Findings from this secondary cohort analysis indicated that tinnitus is associated with a higher risk of benign brain tumors.Neuroepidemiology 2017;49:174 –178 (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 30, 2017 Category: Epidemiology Source Type: research

Double tinnitus in a single ear
. (Source: International Journal of Audiology)
Source: International Journal of Audiology - November 30, 2017 Category: Audiology Authors: Olaf Zag ólski Pawe ł Stręk Source Type: research

The effect of tinnitus specific intracochlear stimulation on speech perception in patients with unilateral or asymmetric hearing loss accompanied with tinnitus and the effect of formal auditory training
. (Source: International Journal of Audiology)
Source: International Journal of Audiology - November 30, 2017 Category: Audiology Authors: Remo A. G. J. Arts Erwin L. J. George Miranda A. M. L. Janssen Andreas Griessner Clemens Zierhofer Robert J. Stokroos Source Type: research

Psychiatric (Axis I) and personality (Axis II) disorders and subjective psychiatric symptoms in chronic tinnitus
. (Source: International Journal of Audiology)
Source: International Journal of Audiology - November 30, 2017 Category: Audiology Authors: Hanna Sahlsten Tero Taiminen Max Karukivi Noora Sj östen Johanna Nikkil ä Juuso Virtanen Janika Paavola Juho Joutsa Katri Niinivirta-Joutsa Mari Takala Anu Holm Esa Rauhala Eliisa L öyttyniemi Reijo Johansson Satu K. J ääskeläinen Source Type: research

Tinnitus and its risk factors in african americans: The Jackson Heart Study
Objectives/HypothesisTo describe the prevalence of reported tinnitus and tinnitus handicap in the all–African American Jackson Heart Study (JHS) cohort, with assessment of the relationship to cardiometabolic risk and depression. Study DesignProspective cohort study. MethodsAudiologic data were obtained from a sample of 1,314 participants of the JHS. Reported tinnitus was assessed dichotomously (yes/no) by interview and with the Tinnitus Handicap Inventory (THI). The statistical relationship of reported tinnitus and tinnitus handicap to various cardiometabolic risks (i.e., hypertension and waist circumference) and Cen...
Source: The Laryngoscope - November 29, 2017 Category: ENT & OMF Authors: Laura House, Charles E. Bishop, Christopher Spankovich, Dan Su, Karen Valle, John Schweinfurth Tags: Otology/Neurotology Source Type: research

Tinnitus, Traumatic Brain Injury, and Posttraumatic Stress Disorder in the Military
ConclusionsAdditional research is warranted to determine the common and unique symptoms and associated neurological pathways of tinnitus, TBI, and PTSD. Brief treatment recommendations are provided, including a multidisciplinary approach for the physical and psychological distress associated with tinnitus. (Source: International Journal of Behavioral Medicine)
Source: International Journal of Behavioral Medicine - November 28, 2017 Category: Psychiatry Source Type: research

Electroencephalographic evaluation of acoustic therapies for the treatment of chronic and refractory tinnitus
To date, a large number of acoustic therapies have been applied to treat tinnitus. The effect that produces those auditory stimuli is, however, not well understood yet. Furthermore, the conventional clinical p... (Source: BMC Ear, Nose and Throat Disorders)
Source: BMC Ear, Nose and Throat Disorders - November 28, 2017 Category: ENT & OMF Authors: Luz Mar ía Alonso-Valerdi, David I. Ibarra-Zarate, Francisco J. Tavira-Sánchez, Ricardo A. Ramírez-Mendoza and Manuel Recuero Tags: Study protocol Source Type: research

Right-Ear Advantage for Speech-in-Noise Recognition in Patients with Nonlateralized Tinnitus and Normal Hearing Sensitivity
In this study, the Quick Speech-in-Noise test (QuickSIN) was conducted monaurally on 14 patients with bilateral tinnitus and 14 age- and hearing-matched adults to determine the relation between tinnitus characteristics and speech understanding. Further, Tinnitus Handicap Inventory (THI), tinnitus loudness magnitude estimation, and loudness matching were obtained to better characterize the perceptual and psychological aspects of tinnitus. The patients reported low THI scores, with most participants in the slight handicap category. Significant between-group differences in speech-in-noise performance were only found at the 5-...
Source: JARO - Journal of the Association for Research in Otolaryngology - November 27, 2017 Category: ENT & OMF Source Type: research

An improved system for grading and treating tinnitus
Tinnitus is an auditory sensation that can cause discomfort or even pain. Because patients with tinnitus frequently have psychological problems, self-reporting of the severity of tinnitus is unreliable. We developed a new grading system and practical protocol for the systematic treatment of tinnitus that accounts for its severity, patients ’ psychological problems, and the frequency of catastrophic episodes. The aim of this study is to employ and validate the new system in patients with tinnitus. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - November 27, 2017 Category: ENT & OMF Authors: Mariko Takahashi, Kayoko Kabaya, Kenichi Sekiya, Futoshi Matsuda, Yoshimasa Sekiya, Shinichi Esaki, Yuji Sato, Akira Inagaki, Shingo Murakami Source Type: research

Gap-induced reductions of evoked potentials in the auditory cortex: a possible objective marker for the presence of tinnitus.
Abstract Animal models of tinnitus are essential for determining the underlying mechanisms and testing pharmacotherapies. However, there is doubt over the validity of current behavioural methods for detecting tinnitus. Here, we applied a stimulus paradigm widely used in a behavioural test (gap-induced inhibition of the acoustic startle reflex GPIAS) while recording from the auditory cortex, and showed neural response changes that mirror those found in the behavioural tests. We implanted guinea pigs (GPs) with electrocorticographic (ECoG) arrays and recorded baseline auditory cortical responses to a startling stimu...
Source: Brain Research - November 27, 2017 Category: Neurology Authors: Berger JI, Owen W, Wilson CA, Hockley A, Coomber B, Palmer AR, Wallace MN Tags: Brain Res Source Type: research

Lateralization effects on functional connectivity of the auditory network in patients with unilateral pulsatile tinnitus as detected by functional MRI
In this study, we recruited 23 left-sided, 23 right-sided PT (LSPT, RSPT) patients and 23 normal controls (NC). We combined applied independent component analysis and seed-based functional connectivity (FC) analysis to investigate alteration feature of the FC of the AN by using resting-state functional magnetic resonance imaging (rs-fMRI). Compared with NC, LSPT patients demonstrated disconnected FC within the AN on both sides. Disrupted network integrity between AN and several brain functional networks, including executive control network, self-perceptual network and the limbic network, was also demonstrated in LSPT patie...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - November 24, 2017 Category: Psychiatry Source Type: research

The Protean Neuropsychiatric and Vestibuloauditory Manifestations of Neurosarcoidosis
Conclusions: Neurosarcoidosis is an elusive diagnosis and can cause hearing loss and psychiatric symptoms. Cochlear implantation for patients with severe hearing loss should be considered once the diagnosis is confirmed, as it is possible to achieve a successful level of hearing. Psychiatric symptoms can manifest with the onset of neurosarcoidosis, result from CN deficits, or develop as a side effect from long-term, high-dose corticosteroids, and should be monitored carefully in patients with neurosarcoidosis.Audiol Neurotol 2017;22:205-217 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - November 22, 2017 Category: Audiology Source Type: research

Transition from Acute to Chronic Tinnitus: Predictors for the Development of Chronic Distressing Tinnitus
Elisabeth Wallh äusser-Franke, Roberto D’Amelio, Anna Glauner, Wolfgang Delb, Jérôme J. Servais, Karl Hörmann, Ines Repik (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - November 20, 2017 Category: Neurology Source Type: research

Impact of chemotherapy-induced neurotoxicities on adult cancer survivors ’ symptom burden and quality of life
AbstractPurposeLimited information is available on the impact of chemotherapy (CTX)-induced neurotoxicity on adult survivors ’ symptom experience and quality of life (QOL). Purposes were to describe occurrence of hearing loss and tinnitus and evaluate for differences in phenotypic characteristics and measures of sensation, balance, perceived stress, symptom burden, and QOL between survivors who received neurotoxic CTX a nd did (i.e., neurotoxicity group) and did not (i.e., no neurotoxicity group) develop neurotoxicity. Neurotoxicity was defined as the presence of chemotherapy-induced neuropathy (CIN), hearing loss, a...
Source: Journal of Cancer Survivorship - November 20, 2017 Category: Cancer & Oncology Source Type: research

Retrospective comparison of three-dimensional imaging sequences in the visualization of posterior fossa cranial nerves
Publication date: December 2017 Source:European Journal of Radiology, Volume 97 Author(s): Suna Ors, Ercan Inci, Rustu Turkay, Atilla Kokurcan, Elif Hocaoglu Purpose To compare efficancy of three-dimentional SPACE (sampling perfection with application-optimized contrasts using different flip-angle evolutions) and CISS (constructive interference in steady state) sequences in the imaging of the cisternal segments of cranial nerves V–XII. Methods Temporal MRI scans from 50 patients (F:M ratio, 27:23; mean age, 44.5±15.9 years) admitted to our hospital with vertigo, tinnitus, and hearing loss were retrospectively...
Source: European Journal of Radiology - November 19, 2017 Category: Radiology Source Type: research

[Neurofeedback for the treatment of chronic tinnitus : Review and future perspectives].
Authors: Kleinjung T, Thüring C, Güntensperger D, Neff P, Meyer M Abstract Neurofeedback is a noninvasive neuromodulation technique employing real-time display of brain activity in terms of electroencephalography (EEG) signals to teach self-regulation of distinct patterns of brain activity or influence brain activity in a targeted manner. The benefit of this approach for control of symptoms in attention deficit disorders, hyperactivity, depression, and migraine has been proven. Studies in recent years have also repeatedly shown this treatment to improve tinnitus symptoms, although it has not become e...
Source: HNO - November 18, 2017 Category: ENT & OMF Tags: HNO Source Type: research

Changes in gray and white matter in subgroups within the tinnitus population.
In this study, we investigated gray and white matter changes in subgroups within the larger tinnitus population related to differences in severity or duration of tinnitus symptoms. Tinnitus is the illusory perception of sound in the absence of an external source, most often experienced as a chronic condition. The psychological reaction to the sound constitutes the severity, or degree of discomfort experienced, and the duration refers to the time since onset of chronic tinnitus. We used voxel- and surface-based morphometry to investigate gray matter changes and diffusion tensor imaging (using fractional anisotropy, or FA, m...
Source: Brain Research - November 17, 2017 Category: Neurology Authors: Schmidt SA, Zimmerman B, Medina ROB, Carpenter-Thompson JR, Husain FT Tags: Brain Res Source Type: research

Hearing impairment is common among Saami adults in Northern Finland.
The objective was to investigate the presence and type of HI among Saami adults, aged 49-77 years (median age 61 years), living in northern Finland. In addition, the presence of self-reported hearing difficulties, difficulties to hear in background noise and tinnitus were studied. An epidemiological, cross-sectional study encompassing a structured interview, otological examination and audiometry was performed. Bilateral HI was present in 42.9% of men and 29.4% of women, when HI was defined as a pure tone average (PTA) of at least 20 dB hearing level (HL) or more at the frequencies of 0.5, 1, 2 and 4 kHz. In one o...
Source: International Journal of Circumpolar Health - November 16, 2017 Category: International Medicine & Public Health Tags: Int J Circumpolar Health Source Type: research

Cochlear Implant Associated Labyrinthitis: A Previously Unrecognized Phenomenon With a Distinct Clinical and Electrophysiological Impedance Pattern
Conclusions: We describe a unique clinical entity, “cochlear implant associated labyrinthitis,” characterized by a distinct constellation of clinical symptoms and corresponding electrode impedance anomalies. The exact cause for this event remains unknown, but may be related to viral illness, delayed foreign body reaction to the electrode, or a reaction to electrical stimulation. Future studies characterizing this unique clinical entity are needed to further elucidate cause and optimal management. (Source: Otology and Neurotology)
Source: Otology and Neurotology - November 15, 2017 Category: ENT & OMF Tags: Cochlear Implants Source Type: research

Prospective Evaluation of Patients Undergoing Translabyrinthine Excision of Vestibular Schwannoma with Concurrent Cochlear Implantation
Conclusions: These data demonstrate preservation of electrical hearing in TL VS surgery is consistently possible, and although speech outcomes do not achieve the same levels seen with other etiologies of hearing loss, excellent improvement in sound localization, improved speech understanding, and substantial reductions in tinnitus are achieved. (Source: Otology and Neurotology)
Source: Otology and Neurotology - November 15, 2017 Category: ENT & OMF Tags: Tumors of the Ear and Cranial Base Source Type: research

Petrous Apex Cholesterol Granulomas: Outcomes, Complications, and Hearing Results From Surgical and Wait-and-Scan Management
Conclusion: Surgical drainage is preferable to more aggressive resection procedures, with the latter reserved for recurrent lesions or lesions with severe hearing loss/involvement of critical neurovascular structures. ITF-B approach provides adequate cyst and neurovascular control for resection, while avoiding brain retraction. An initial wait-and-scan approach can be used in most patients where symptoms and imaging justify so. (Source: Otology and Neurotology)
Source: Otology and Neurotology - November 15, 2017 Category: ENT & OMF Tags: Tumors of the Ear and Cranial Base Source Type: research

Management of Sigmoid Sinus Associated Pulsatile Tinnitus: A Systematic Review of the Literature
Conclusion: PT as a result of sigmoid sinus diverticula, aneurysms, and dehiscence is a rare, but largely treatable condition. Available interventions include SSW R/R, endovascular intervention, and cardiac U-clip techniques. In SSW R/R, bone pate, unspecified soft-tissue graft, and bone cement had the highest rates of PT resolution. While temporalis fascia and autologous bone chips were the materials most commonly used, they had significantly lower rates of PT resolution compared with the other materials, with the exception of auricular cartilage and bone cement. Most episodes of recurrence are resolved with medical manag...
Source: Otology and Neurotology - November 15, 2017 Category: ENT & OMF Tags: Review Article Source Type: research

The Etiological Relationship Between Migraine and Sudden Hearing Loss
Conclusion: SSNHL patients had a higher prevalence of migraine. Although those with migraine had higher recovery rates, the differences were not statistically significant. (Source: Otology and Neurotology)
Source: Otology and Neurotology - November 15, 2017 Category: ENT & OMF Tags: Sensorineural Hearing Loss and Tinnitus Source Type: research

STRC Deletion is a Frequent Cause of Slight to Moderate Congenital Hearing Impairment in the Czech Republic
Conclusions: Following GJB2, STRC was the second most frequently mutated gene in patients from the Czech Republic with hearing loss. To decrease the cost of testing, we recommend STRC deletion screening with MLPA before next-generation sequencing. The existence of a pseudogene and polymorphic STRC regions can lead to false-positive or false-negative results when copy number variation analysis is based on next-generation sequencing data. (Source: Otology and Neurotology)
Source: Otology and Neurotology - November 15, 2017 Category: ENT & OMF Tags: Sensorineural Hearing Loss and Tinnitus Source Type: research

Electrode Impedance Fluctuations as a Biomarker for Inner Ear Pathology After Cochlear Implantation
Conclusion: Our results suggest that there is a relationship between a spike and the loss of residual hearing. It seems that rises in impedance can reflect pathology within the inner ear and predict the future loss of residual hearing. (Source: Otology and Neurotology)
Source: Otology and Neurotology - November 15, 2017 Category: ENT & OMF Tags: Cochlear Implants Source Type: research

Glutamate is down-regulated and tinnitus loudness-levels decreased following rTMS over auditory cortex of the left hemisphere: A prospective randomized single-blinded sham-controlled cross-over study.
Abstract Using a prospective randomized single-blinded sham-controlled cross-over design, we studied the efficacy of low frequency (1-Hz) repetitive transcranial magnetic stimulation (rTMS) over auditory cortex of the left temporal lobe as an experimental treatment modality for noise-induced tinnitus. Pre/post outcome measures for sham vs. active rTMS conditions included differential changes in tinnitus loudness, self-perceived changes in the Tinnitus Handicap Questionnaire (THQ), and neurochemical changes of brain metabolite concentrations using single voxel proton magnetic resonance spectroscopy ((1)H-MRS) obtai...
Source: Hearing Research - November 14, 2017 Category: Audiology Authors: Cacace AT, Hu J, Romero S, Xuan Y, Burkard RF, Tyler RS Tags: Hear Res Source Type: research

Tinnitus and Hearing Survey: A Polish Study of Validity and Reliability in a Clinical Population
In conclusion, the THS-POL is a valid and reliable screening tool to assist in deciding about the optimal management approach.Audiol Neurotol 2017;22:197-204 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - November 10, 2017 Category: Audiology Source Type: research

Performance of the Tinnitus Functional Index as a diagnostic instrument in a UK clinical population.
CONCLUSION: The TFI was confirmed to cover multiple symptom domains, measuring a multi-domain construct of tinnitus, and satisfies a range of psychometric requirements for a good clinical measure, including having excellent reliability, stability over time and sensitivity to individual differences in tinnitus severity. However, a modified seven-factor structure without the Auditory subscale (TFI-22) is recommended for calculating a global composite score for UK patients. Using patients' experience and Receiver Operator Characteristic analysis, a grading system was presented which identifies the distinct grades of tinnitus ...
Source: Hearing Research - November 9, 2017 Category: Audiology Authors: Fackrell K, Hall DA, Barry JG, Hoare DJ Tags: Hear Res Source Type: research

Internal jugular vein stenosis induced intracranial hypertension can be resolved by stenting
Abstract BackgroundIdiopathic intracranial hypertension (IIH) is characterized by abnormally elevated intracranial pressure (ICP) without identifiable etiology. Recently, however, a subset of patients with presumed IIH have been found with isolated internal jugular vein (IJV) stenosis in the absence of intracranial abnormalities. MethodsFifteen consecutive patients were screened from 46 patients suspected as IIH and were finally confirmed as isolated IJV stenosis. The stenotic IJV was corrected with stenting when a trans‐stenotic mean pressure gradient (∆MPG) was equal or higher than 5.44 cmH2O. Dynamic MRV/CTV/DSA of ...
Source: European Journal of Neurology - November 8, 2017 Category: Neurology Authors: Da Zhou, Ran Meng, Xuxiang Zhang, Linlin Guo, Sijie Li, Weijuan Wu, Jiangang Duan, Haiqing Song, Yuchuan Ding, Xunming Ji Tags: Original Article Source Type: research

The importance of audiometric monitoring in patients with multidrug-resistant tuberculosis
CONCLUSIONS: Evaluations of ototoxicity symptoms were not usually reported in the routine care of patients with MDR-TB. Complaints of tinnitus were associated with amikacin and streptomycin use. These results require confirmation in future studies. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - November 6, 2017 Category: Tropical Medicine Source Type: research

Alexithymia Is Associated with Tinnitus Severity
Jan Wielopolski, Tobias Kleinjung, Melanie Koch, Nicole Peter, Martin Meyer, Michael Rufer, Steffi Weidt (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - November 6, 2017 Category: Psychiatry Source Type: research

Pediatric tinnitus: A clinical perspective
ConclusionsThis study distinguishes pediatric tinnitus from adult tinnitus in terms of lower association with underlying hearing loss, lower likelihood of reported anxiety, and higher likelihood of improvement and resolution. There are opportunities for tinnitus prevention in the areas of reducing head injury and noise‐induced hearing loss. Level of Evidence4 Laryngoscope, 2017 (Source: The Laryngoscope)
Source: The Laryngoscope - November 6, 2017 Category: ENT & OMF Authors: Kenny H. Chan, Emily L. Jensen, Dexiang Gao Tags: Pediatrics Source Type: research

Higher prevalence and increased severity of sleep ‐disordered breathing in male patients with chronic tinnitus: our experience with 173 cases
This article is protected by copyright. All rights reserved. (Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - November 6, 2017 Category: ENT & OMF Authors: Jen ‐Tsung Lai, Ping‐Hung Shen, Che‐Yang Lin, Chun‐Lin Liu, Tien‐Chen Liu Tags: Our Experience Source Type: research