The Role of miRNA in Testicular Cancer: Current Insights and Future Perspectives
Conclusions: MiRNAs could represent a reliable tool for accurate diagnosis and disease monitoring in the treatment of TGCT, providing more precise tools for early detection and treatment stratification. Nevertheless, well-designed clinical trials and comprehensive long-term data are needed to ensure their translation into effective clinical tools.PMID:38004082 | PMC:PMC10672751 | DOI:10.3390/medicina59112033 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - November 25, 2023 Category: Universities & Medical Training Authors: Francesco Ditonno Antonio Franco Celeste Manfredi Daniela Fasanella Marco Abate Roberto La Rocca Fabio Crocerossa Vincenzo Iossa Ugo Giovanni Falagario Luigi Cirillo Vincenzo Maria Altieri Ernesto Di Mauro Felice Crocetto Biagio Barone Simone Cilio Savio Source Type: research
The Role of miRNA in Testicular Cancer: Current Insights and Future Perspectives
Conclusions: MiRNAs could represent a reliable tool for accurate diagnosis and disease monitoring in the treatment of TGCT, providing more precise tools for early detection and treatment stratification. Nevertheless, well-designed clinical trials and comprehensive long-term data are needed to ensure their translation into effective clinical tools.PMID:38004082 | PMC:PMC10672751 | DOI:10.3390/medicina59112033 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - November 25, 2023 Category: Universities & Medical Training Authors: Francesco Ditonno Antonio Franco Celeste Manfredi Daniela Fasanella Marco Abate Roberto La Rocca Fabio Crocerossa Vincenzo Iossa Ugo Giovanni Falagario Luigi Cirillo Vincenzo Maria Altieri Ernesto Di Mauro Felice Crocetto Biagio Barone Simone Cilio Savio Source Type: research
The Role of miRNA in Testicular Cancer: Current Insights and Future Perspectives
Conclusions: MiRNAs could represent a reliable tool for accurate diagnosis and disease monitoring in the treatment of TGCT, providing more precise tools for early detection and treatment stratification. Nevertheless, well-designed clinical trials and comprehensive long-term data are needed to ensure their translation into effective clinical tools.PMID:38004082 | PMC:PMC10672751 | DOI:10.3390/medicina59112033 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - November 25, 2023 Category: Universities & Medical Training Authors: Francesco Ditonno Antonio Franco Celeste Manfredi Daniela Fasanella Marco Abate Roberto La Rocca Fabio Crocerossa Vincenzo Iossa Ugo Giovanni Falagario Luigi Cirillo Vincenzo Maria Altieri Ernesto Di Mauro Felice Crocetto Biagio Barone Simone Cilio Savio Source Type: research
The Role of miRNA in Testicular Cancer: Current Insights and Future Perspectives
Conclusions: MiRNAs could represent a reliable tool for accurate diagnosis and disease monitoring in the treatment of TGCT, providing more precise tools for early detection and treatment stratification. Nevertheless, well-designed clinical trials and comprehensive long-term data are needed to ensure their translation into effective clinical tools.PMID:38004082 | PMC:PMC10672751 | DOI:10.3390/medicina59112033 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - November 25, 2023 Category: Universities & Medical Training Authors: Francesco Ditonno Antonio Franco Celeste Manfredi Daniela Fasanella Marco Abate Roberto La Rocca Fabio Crocerossa Vincenzo Iossa Ugo Giovanni Falagario Luigi Cirillo Vincenzo Maria Altieri Ernesto Di Mauro Felice Crocetto Biagio Barone Simone Cilio Savio Source Type: research
The Role of miRNA in Testicular Cancer: Current Insights and Future Perspectives
Conclusions: MiRNAs could represent a reliable tool for accurate diagnosis and disease monitoring in the treatment of TGCT, providing more precise tools for early detection and treatment stratification. Nevertheless, well-designed clinical trials and comprehensive long-term data are needed to ensure their translation into effective clinical tools.PMID:38004082 | PMC:PMC10672751 | DOI:10.3390/medicina59112033 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - November 25, 2023 Category: Universities & Medical Training Authors: Francesco Ditonno Antonio Franco Celeste Manfredi Daniela Fasanella Marco Abate Roberto La Rocca Fabio Crocerossa Vincenzo Iossa Ugo Giovanni Falagario Luigi Cirillo Vincenzo Maria Altieri Ernesto Di Mauro Felice Crocetto Biagio Barone Simone Cilio Savio Source Type: research
The Role of miRNA in Testicular Cancer: Current Insights and Future Perspectives
Conclusions: MiRNAs could represent a reliable tool for accurate diagnosis and disease monitoring in the treatment of TGCT, providing more precise tools for early detection and treatment stratification. Nevertheless, well-designed clinical trials and comprehensive long-term data are needed to ensure their translation into effective clinical tools.PMID:38004082 | PMC:PMC10672751 | DOI:10.3390/medicina59112033 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - November 25, 2023 Category: Universities & Medical Training Authors: Francesco Ditonno Antonio Franco Celeste Manfredi Daniela Fasanella Marco Abate Roberto La Rocca Fabio Crocerossa Vincenzo Iossa Ugo Giovanni Falagario Luigi Cirillo Vincenzo Maria Altieri Ernesto Di Mauro Felice Crocetto Biagio Barone Simone Cilio Savio Source Type: research
The Role of miRNA in Testicular Cancer: Current Insights and Future Perspectives
Conclusions: MiRNAs could represent a reliable tool for accurate diagnosis and disease monitoring in the treatment of TGCT, providing more precise tools for early detection and treatment stratification. Nevertheless, well-designed clinical trials and comprehensive long-term data are needed to ensure their translation into effective clinical tools.PMID:38004082 | PMC:PMC10672751 | DOI:10.3390/medicina59112033 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - November 25, 2023 Category: Universities & Medical Training Authors: Francesco Ditonno Antonio Franco Celeste Manfredi Daniela Fasanella Marco Abate Roberto La Rocca Fabio Crocerossa Vincenzo Iossa Ugo Giovanni Falagario Luigi Cirillo Vincenzo Maria Altieri Ernesto Di Mauro Felice Crocetto Biagio Barone Simone Cilio Savio Source Type: research
The Role of miRNA in Testicular Cancer: Current Insights and Future Perspectives
Conclusions: MiRNAs could represent a reliable tool for accurate diagnosis and disease monitoring in the treatment of TGCT, providing more precise tools for early detection and treatment stratification. Nevertheless, well-designed clinical trials and comprehensive long-term data are needed to ensure their translation into effective clinical tools.PMID:38004082 | PMC:PMC10672751 | DOI:10.3390/medicina59112033 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - November 25, 2023 Category: Universities & Medical Training Authors: Francesco Ditonno Antonio Franco Celeste Manfredi Daniela Fasanella Marco Abate Roberto La Rocca Fabio Crocerossa Vincenzo Iossa Ugo Giovanni Falagario Luigi Cirillo Vincenzo Maria Altieri Ernesto Di Mauro Felice Crocetto Biagio Barone Simone Cilio Savio Source Type: research
The Role of miRNA in Testicular Cancer: Current Insights and Future Perspectives
Conclusions: MiRNAs could represent a reliable tool for accurate diagnosis and disease monitoring in the treatment of TGCT, providing more precise tools for early detection and treatment stratification. Nevertheless, well-designed clinical trials and comprehensive long-term data are needed to ensure their translation into effective clinical tools.PMID:38004082 | PMC:PMC10672751 | DOI:10.3390/medicina59112033 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - November 25, 2023 Category: Universities & Medical Training Authors: Francesco Ditonno Antonio Franco Celeste Manfredi Daniela Fasanella Marco Abate Roberto La Rocca Fabio Crocerossa Vincenzo Iossa Ugo Giovanni Falagario Luigi Cirillo Vincenzo Maria Altieri Ernesto Di Mauro Felice Crocetto Biagio Barone Simone Cilio Savio Source Type: research
The Role of miRNA in Testicular Cancer: Current Insights and Future Perspectives
Conclusions: MiRNAs could represent a reliable tool for accurate diagnosis and disease monitoring in the treatment of TGCT, providing more precise tools for early detection and treatment stratification. Nevertheless, well-designed clinical trials and comprehensive long-term data are needed to ensure their translation into effective clinical tools.PMID:38004082 | PMC:PMC10672751 | DOI:10.3390/medicina59112033 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - November 25, 2023 Category: Universities & Medical Training Authors: Francesco Ditonno Antonio Franco Celeste Manfredi Daniela Fasanella Marco Abate Roberto La Rocca Fabio Crocerossa Vincenzo Iossa Ugo Giovanni Falagario Luigi Cirillo Vincenzo Maria Altieri Ernesto Di Mauro Felice Crocetto Biagio Barone Simone Cilio Savio Source Type: research
Omics sciences and precision medicine in testicular cancer
CONCLUSIONS: In order to comprehend cancer better and to discover new biomarkers and therapeutic targets, oncologists are increasingly employing omics methods, such as genomics, transcriptomics, proteomics, and metabolomics. Targeted medications that focus on specific genetic pathways and mutations hold promise for advancing the diagnosis and management of this disease.PMID:37994745 | DOI:10.7417/CT.2023.2468 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - November 23, 2023 Category: Cancer & Oncology Authors: G Madeo G Bonetti P E Maltese B Tanzi S Tezzele C Mareso F Agostini D Generali C A Donofrio M Cominetti A Fioravanti L Riccio T Beccari M R Ceccarini A E Calogero R Cannarella L Stuppia L Stuppia V Gatta M Nughman S Cecchin G Marceddu M Bertelli Source Type: research
Omics sciences and precision medicine in testicular cancer
CONCLUSIONS: In order to comprehend cancer better and to discover new biomarkers and therapeutic targets, oncologists are increasingly employing omics methods, such as genomics, transcriptomics, proteomics, and metabolomics. Targeted medications that focus on specific genetic pathways and mutations hold promise for advancing the diagnosis and management of this disease.PMID:37994745 | DOI:10.7417/CT.2023.2468 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - November 23, 2023 Category: Cancer & Oncology Authors: G Madeo G Bonetti P E Maltese B Tanzi S Tezzele C Mareso F Agostini D Generali C A Donofrio M Cominetti A Fioravanti L Riccio T Beccari M R Ceccarini A E Calogero R Cannarella L Stuppia L Stuppia V Gatta M Nughman S Cecchin G Marceddu M Bertelli Source Type: research
Molecular characterization of the CXCR4 / CXCR7 axis in germ cell tumors and its targetability using nanobody-drug-conjugates
This study identified a nanobody-drug-conjugate targeting CXCR4 as a putative therapeutic option for GCT, i.e. seminoma and yolk-sac tumors. Furthermore, this study shed light on the functional role of the CXCR4 / CXCR7 / CXCL12-signaling cascade in GCT, demonstrating an import ant influence on proliferation and migration. (Source: Experimental Hematology and Oncology)
Source: Experimental Hematology and Oncology - November 23, 2023 Category: Cancer & Oncology Source Type: research
Overexpression of SerpinB9 in non-seminomatous germ cell tumors
Med Mol Morphol. 2023 Nov 22. doi: 10.1007/s00795-023-00374-9. Online ahead of print.ABSTRACTSerpinb9 is an inhibitor of granzyme B and is potentially involved in the immune escape of tumor cells. In the present study, bioinformatics analysis using open databases suggested that SerpinB9 is overexpressed in testicular embryonal carcinoma. Immunohistological analysis was performed on 28 cases of testicular germ cell tumors to investigate the relationship between SerpinB9 expression in testicular germ cell tumors and the tumor immune environment. SerpinB9 was significantly upregulated in the non-seminoma group and inversely c...
Source: Molecular Medicine - November 22, 2023 Category: Molecular Biology Authors: Toshiki Anami Yuki Ibe Lianbo Li Yoshihiro Komohara Hiroki Hirao Mamoru Harada Hiromu Yano Yukio Fujiwara Takanobu Motoshima Junji Yatsuda Taizo Hibi Tomomi Kamba Source Type: research
