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Multiomic Analysis of Infection in Sudden Infant Death Syndrome
This case-control study investigates if a subset of sudden infant deaths are associated with undiagnosed neuroinflammation and occult infection. (Source: JAMA Neurology)
Source: JAMA Neurology - January 29, 2024 Category: Neurology Source Type: research

GSE245891 Transcriptomic analysis of neuroinflammation and occult infection in sudden infant death syndrome
Contributor : Benjamin OkatySeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAntemortem infection is a risk factor for sudden infant death syndrome (SIDS) – the leading postneonatal cause of infant mortality in the developed world. Manifestations of infection and attendant inflammation, however, are not always apparent in clinical settings or by standard autopsy, thus enhanced resolution approaches are needed. Here we screened postmortem SIDS tissue s and fluids for inflammatory markers and applied metagenomics and transcriptomics to a subset of cases to look for evidence of occult ...
Source: GEO: Gene Expression Omnibus - January 4, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

Inflammation in sudden infant death syndrome
Pediatr Res. 2023 Dec 15. doi: 10.1038/s41390-023-02966-8. Online ahead of print.NO ABSTRACTPMID:38097722 | DOI:10.1038/s41390-023-02966-8 (Source: Pediatric Research)
Source: Pediatric Research - December 14, 2023 Category: Pediatrics Authors: Peter M MacFarlane Source Type: research

Revisiting the association of sudden infant death syndrome (SIDS) with polymorphisms of NHE3 and IL13
ConclusionOur findings suggest an association ofNHE3 variant rs2247114 (C2405T), though not rs71597645 (NHE3), with SIDS. A potential role of rs20541 (IL13) still has to be elucidated. Especially NHE3 seems to be an interesting topic for future SIDS research. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - December 13, 2023 Category: Medical Law Source Type: research

Deaths: Leading Causes for 2020
This report presents final 2020 data on the 10 leading causes of death in the United States by age, race and Hispanic origin, and sex. Leading causes of infant, neonatal, and postneonatal death are also presented. This report supplements "Deaths: Final Data for 2020," the National Center for Health Statistics' annual report of final mortality statistics. Methods-Data in this report are based on information from all death certificates filed in the 50 states and the District of Columbia in 2020. Causes of death classified by the International Classification of Diseases, 10th Revision (ICD-10) are ranked according to the numb...
Source: Natl Vital Stat Rep - December 12, 2023 Category: Statistics Authors: Sally C Curtin Betzaida Tejada-Vera Brigham A Bastian Source Type: research