Wednesday Bible Study: A public health lesson
Psalm 90 is attributed to Moses. At least David might have existed, although he certainly did not write the psalms attributed to him. Moses is an entirely fictitious character. We know for a fact that the Egyptian captivity and the exodus never happened. But I ' ll give the writer this much credit -- the human lifespan of 70 years was probably pretty accurate at the time, in the sense that it was about the longest people could hope to live. You may recall that in Genesis 6:3 God says the human lifespan will be 120 years, and that many of the characters in Genesis lived for hundreds of years. However, life expectancy -...
Source: Stayin' Alive - April 3, 2024 Category: American Health Source Type: blogs

Arguing the Primacy of Predation in Determining Species Longevity
Researchers here review a variety of species and conclude that defense against predation is the most important determinant of species longevity. Long-lived species tend to have shells, or fly, or live underground. Evolution will not favor longevity until other factors reduce extrinsic mortality at the hands of predators. After that, proximate biochemical causes of longevity can come into play in what looks to be a wide variety of ways. Various environmental morphological and behavioral factors can determine the longevity of representatives of various taxa. Long-lived species develop systems aimed at increasing org...
Source: Fight Aging! - April 3, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

A View of Type 2 Diabetes as Accelerated Aging
The mortality characteristics resulting from type 2 diabetes look very much like an accelerated form of normal aging, as noted in today's open access paper reporting on a large epidemiological study. This mortality characteristic is so much like aging that at times in the past researchers have used animal models of type 2 diabetes as stand-ins for aging, in order to conduct studies more rapidly. Type 2 diabetes is a metabolic disease, a condition that usually arises from excess fat tissue, and is characterized by chronic inflammation, excessive blood sugar, high levels of circulating advanced glycation end-products, and ot...
Source: Fight Aging! - April 2, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Lewy Body Disease May Be More Common than Thought
Access to human brain tissue for medical research is more limited than most people realize is the case, and, for obvious reasons, far too little of the available tissue data covers the early stages of disease. This limitation is one of the factors slowing the pace of research into age-related neurodegenerative conditions. Here, for example, researchers make use of an unusual resource to show that the prevalence of Lewy body disease may be greater than presently thought, with pathology beginning in the 50s, even if there are no outright symptoms of disease at that stage. Lewy body disease is the second most common ...
Source: Fight Aging! - April 2, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

A Stem Cell Secretome Treatment Improves Measures of Health in Old Mice
In this study, we tested a stem cell secretome product, which contains extracellular vesicles and growth factors, cytoskeletal remodeling factors, and immunomodulatory factors. We examined the effects of 4 weeks of 2×/week unilateral intramuscular secretome injections (quadriceps) in ambulatory aged male C57BL/6 mice (22-24 months) compared to saline-injected aged-matched controls. Secretome delivery substantially increased whole-body lean mass and decreased fat mass, corresponding to higher myofiber cross-sectional area and smaller adipocyte size, respectively. Secretome-treated mice also had greater whole-bod...
Source: Fight Aging! - April 1, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

The Best Beauty Advice From Science You Will Get Today (M)
Study tested the effects of poor sleep on two consecutive nights. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 31, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Attractiveness Social psychology subscribers-only Source Type: blogs

Bonus Features – March 31, 2024 – 55% of Change Healthcare customers expect adverse impacts on patient care, a mobile app helped 84% of seniors lower their blood pressure after 6 months, plus 19 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News The State Department is offering a reward of up to $10 million for information about the ALPHV BlackCat ransomware-as-a-service group that was behind the Change Healthcare cyberattack. A report from HFMA and Eliciting Insig...
Source: EMR and HIPAA - March 31, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT AdvancedMD Bitsight Carequality CENTEGIX CentralReach Closed Loop Medicine David Stevens Diligent Eliciting Insights Experity FrontRunnerHC Healthcare IT Today Bonus Features Hello Heart HFMA Incite Strategic Pa Source Type: blogs

Fight Aging! Newsletter, April 1st 2024
This study supports the proposed model that aging-related loss of colonic crypt epithelial cell AMP gene expression can promote increased relative abundances of Gn inflammaging-associated bacteria and gene expression markers of colonic inflammaging. These data may support new targets for aging-related therapies based on intestinal genes and microbiomes. « Back to Top A Skeptical View of the Role of Nuclear DNA Damage in Aging https://www.fightaging.org/archives/2024/03/a-skeptical-view-of-the-role-of-nuclear-dna-damage-in-aging/ It is evident and settled that stochastic nuclear DNA damag...
Source: Fight Aging! - March 31, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Low-frequency ultrasound for pain relief [PODCAST]
Subscribe to The Podcast by KevinMD. Watch on YouTube. Catch up on old episodes! We welcome L. Joseph Parker, a research physician, as we delve into a study that explores the potential of low-frequency ultrasound waves in pain management. Joseph will guide us through the intriguing findings of this study, shedding light on how targeted Read more… Low-frequency ultrasound for pain relief [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 30, 2024 Category: General Medicine Authors: Tags: Podcast Pain Management Source Type: blogs

Weekly Roundup – March 30, 2024
Welcome to our Healthcare IT Today Weekly Roundup. Each week, we’ll be providing a look back at the articles we posted and why they’re important to the healthcare IT community. We hope this gives you a chance to catch up on anything you may have missed during the week. Leveraging an Outside Provider for the EHR Service Desk. UI Health CIO Audrius Polikaitis talked to John about how the Illinois health system consolidated its help desk onto a “single front door” powered by HCTec. The move proved helpful following a transition to Epic and powered virtual onboarding during the pandemic. Read more… ItR...
Source: EMR and HIPAA - March 30, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Weekly Roundup Source Type: blogs

Ebstein ’ s Anomaly of Tricuspid Valve
Transcript of the video: Ebstein’s Anomaly is one of the cyanotic congenital heart disease in which survival to adult life is common. In Ebstein’s anomaly, there is downward or apical displacement of posterior and septal tricuspid leaflets. The anterior leaflet is not displaced, but is elongated to meet the other leaflets, so that when it closes, a loud sound, tricuspid sound, is produced, which is called as the sail sound. Ebstein’s anomaly may be associated with atrial septal defect or a patent foramen ovale, in about 50% of cases. The cyanosis in Ebstein’s anomaly, is usually not due to pulmonary...
Source: Cardiophile MD - March 30, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

The Long and Tortured History of Alpha-Synuclein and Parkinson ’s Disease
This study tracks the decades-long journey to harness alpha-synuclein as a treatment for Parkinson’s disease. Steven Zecola an activist who tracks Parkinson’s research and was on THCB last month discussing it, offers three key changes needed to overcome the underlying challenges. A Quick Start for Alpha-Synuclein R&D In the mid-1990’s, Parkinson’s patient advocacy groups had become impatient by the absence of any major therapeutic advances in the 25 years since L-dopa had been approved for Parkinson’s disease (PD). The Director of National Institute of Neurological Disorders and Stroke (NINDS) se...
Source: The Health Care Blog - March 29, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice Parkinson's Disease Steven Zecola Source Type: blogs

Overjet Raises $53 Million: The Largest Investment in the History of Dental AI
With this Series C Funding, Overjet will Expand its AI Platform to Create the First Unified Standard for Dental Providers and Payers — Allowing Them to Give Patients the Best Possible Care Overjet, the world leader in dental AI, today announced a $53.2 million Series C round: the largest investment ever in artificial intelligence for dentistry. The historic round was led by March Capital, with participation from General Catalyst, Insight Partners, E14 Fund, Crosslink Capital, Spring Rock Capital, Liquid 2 Ventures, and Harmonic Growth Partners, as well as the American Dental Association. It brings Overjet’s total ...
Source: EMR and HIPAA - March 29, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Aligned Dental Partners American Dental Association Crosslink Capital E14 Fund General Catalyst Harmonic Growth Partners Health IT Funding Health IT Fundings Health IT Investment Insight Partners Liq Source Type: blogs

Tristetraprolin Upregulation Reduces Frailty and Increases Bone Density in Old Mice
Researchers here report that life-long tristetraprolin (TTP) upregulation leads to reduced frailty and improved bone mineral density in aged mice. One of the functions of TTP is that it suppresses expression of the pro-inflammatory TNF-α cytokine, so a reduced degree of age-related inflammation would be the first place to look for an explanation of the outcome noted here. It is an open question as to whether TTP upregulation produces a more nuanced and reactive reduction of TNF-α signaling than is the case for the blunt, across the board inhibition achieved by present anti-TNF-α therapies, and is thus a mechanism that i...
Source: Fight Aging! - March 29, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Advantages, Challenges, and Costs of Healthcare at Home Services
Switching to fully remote operations during the pandemic was a rushed adventure into what was mostly uncharted territory. There were a lot of challenges and bugs to work out, but there were also plenty of advantages and unforeseen benefits. And it is thanks to those advantages and benefits that healthcare at home is continuing, even as there are still challenges to work on and in-person operations return. While our first big push into remote care was a leap into the unknown, this time we want to make sure that we are surveying the landscape to make this a safe, smart, and financially responsible decision. So let’s ta...
Source: EMR and HIPAA - March 28, 2024 Category: Information Technology Authors: Grayson Miller Tags: Clinical Health IT Company Healthcare IT Hospital - Health System LTPAC Revenue Cycle Management Telemedicine and Remote Monitoring Alaina Victoria Ash Wellness Brenden Hayden Carenet Health Carium Chris Darland David McCormick Source Type: blogs