Selective reduction of oxidative stress markers in the SAMP8 mouse brain by a distinct spearmint extract with antioxidant properties. (P4.078)
CONCLUSIONS: Neumentix supplementation improved learning and memory and selectively reduced brain tissue markers of oxidative stress in a mouse model of accelerated aging. Moreover, these results suggest Neumentix supplementation may attenuate oxidative changes that occur with aging and cognitive decline. Study Supported by:Kemin Foods,L.C.Disclosure: Dr. Farr has received research support from Kemin Foods, L.C. Dr. Fonsec has received personal compensation for activities with Kemin Foods, L.C. as an employee. Dr. Herrlinger has received personal compensation for activities with Kemin Foods, L.C. as an employee. Dr. Niema...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Farr, S., Fonseca, B., Herrlinger, K., Nieman, K., Ceddia, M., Fullmer, L., Niehoff, M., Lewis, B., Welleford, A., Butterfield, D., Morley, J. Tags: Aging, Dementia, Cognitive, and Behavioral Neurology: Basic and Pre-clinical Studies Source Type: research

The effects of essential oil treatment on the biogenic amines inhibition and quality preservation of red drum (Sciaenops ocellatus) fillets
Publication date: October 2015 Source:Food Control, Volume 56 Author(s): Luyun Cai , Ailing Cao , Yingchang Li , Zhuo Song , Liping Leng , Jianrong Li Several naturally occurring essential oils were evaluated for their effectiveness in maintaining post-mortem quality and extending shelf life of red drum (Sciaenops ocellatus). Fresh fish fillets were treated with 4 μl/L clove, cumin and spearmint oils at 10 °C for 2 h and the hardness, pH value, K-value, TCA-soluble peptides, sensory evaluation, biogenic amines and microbiological characteristics determined. The results showed that the fillets treated with sp...
Source: Food Control - April 7, 2015 Category: Food Science Source Type: research

Plants used during pregnancy, childbirth, postpartum and infant healthcare in Palestine.
CONCLUSION: This study revealed that there is an appreciable prevalence of herbal use among pregnant women at different pregnancy stages and for infant healthcare in Palestine. PMID: 25900613 [PubMed - as supplied by publisher] (Source: Complementary Therapies in Clinical Practice)
Source: Complementary Therapies in Clinical Practice - April 2, 2015 Category: Complementary Medicine Authors: Ali-Shtayeh MS, Jamous RM, Jamous RM Tags: Complement Ther Clin Pract Source Type: research

Functional analysis of (4S)-limonene synthase [Biochemistry]
Crystal structural data for (4S)-limonene synthase [(4S)-LS] of spearmint (Mentha spicata L.) were used to infer which amino acid residues are in close proximity to the substrate and carbocation intermediates of the enzymatic reaction. Alanine-scanning mutagenesis of 48 amino acids combined with enzyme fidelity analysis [percentage of (−)-limonene produced] indicated... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - March 17, 2015 Category: Science Authors: Srividya, N., Davis, E. M., Croteau, R. B., Lange, B. M. Tags: Biological Sciences Source Type: research

The safety of a dry spearmint extract in vitro and in vivo
Publication date: Available online 16 December 2014 Source:Regulatory Toxicology and Pharmacology Author(s): Joanne A. Lasrado , Debbie Trinker , Michael A. Ceddia , Kelli A. Herrlinger A proprietary dry spearmint extract standardized to 15.4% rosmarinic acid was assessed in a 90-day study with Sprague–Dawley rats that were gavaged at 0, 422 (low), 844 (mid), or 1948 (high) mg dry spearmint extract/kg bw/day, (equivalent to 0, 65, 130, or 300mg rosmarinic acid/kg bw/day, respectively). No treatment-related clinical signs or adverse effects were observed in body weight, feed consumption, neurological parameters, h...
Source: Regulatory Toxicology and Pharmacology - December 23, 2014 Category: Toxicology Source Type: research

The safety of a dry spearmint extract in vitro and in vivo.
Abstract A proprietary dry spearmint extract standardized to 15.4% rosmarinic acid was assessed in a 90-day study with Sprague-Dawley rats that were gavaged at 0, 422 (low), 844 (mid), or 1948 (high) mg dry spearmint extract/kg bw/day, (equivalent to 0, 65, 130, or 300mg rosmarinic acid/kg bw/day, respectively). No treatment-related clinical signs or adverse effects were observed in body weight, feed consumption, neurological parameters, hematology, clinical chemistry, gross pathology, and histopathology. However, there were statistically significant increases in the absolute and relative weight of the pit...
Source: Regulatory Toxicology and Pharmacology : RTP - December 16, 2014 Category: Toxicology Authors: Lasrado JA, Trinker D, Ceddia MA, Herrlinger KA Tags: Regul Toxicol Pharmacol Source Type: research

Assessment of Polyphenol Coated Nano Zero Valent Iron for Hexavalent Chromium Removal from Contaminated Waters.
Abstract Alternative plant extracts were examined as raw materials for the synthesis of nZVI from ferric solutions. Four plants were selected for evaluation, i.e. Camellia sinensis (green tea, GT), Syzygium aromaticum (clove, CL), Mentha spicata (spearmint, SM) and Punica granatum (pomegranate, PG). Based on the results obtained, it was concluded that the reduction of Fe(III) with the herb extracts is not complete. Using the GT extract, approximately 28 mM of the initial 66 mM of Fe (42.4 %) are reduced to the elemental state Fe(0). The highest reduction of Fe(III), about 53 %, was achieved with PG and...
Source: Bulletin of Environmental Contamination and Toxicology - December 16, 2014 Category: Environmental Health Authors: Mystrioti C, Sparis D, Papasiopi N, Xenidis A, Dermatas D, Chrysochoou M Tags: Bull Environ Contam Toxicol Source Type: research

Next generation sequencing unravels the biosynthetic ability of Spearmint ( Mentha spicata ) peltate glandular trichomes through comparative transcriptomics
Conclusions: The extensive transcriptome data set renders a complete description of genes differentially expressed in spearmint PGT. This will facilitate the metabolic engineering of mint terpene pathway to increase yield and also enable the development of strategies for sustainable production of novel or altered valuable compounds in mint. (Source: BMC Plant Biology)
Source: BMC Plant Biology - November 1, 2014 Category: Biology Authors: Jingjing JinDeepa PanickerQian WangMi KimJun LiuJun-Lin YinLimsoon WongIn-Cheol JangNam-Hai ChuaRajani Sarojam Source Type: research

Phytotherapy for Polycystic Ovarian Syndrome: A review of the literature and evaluation of practitioners’ experiences
Conclusions This exploratory study suggests that there is a role for phytotherapy in the treatment of PCOS. Further investigation, consisting of well-designed clinical trials and monitoring the successful use of herbal medicine by practitioners, is clearly necessary. This future research would serve to substantiate positive empirical evidence, constructing a more robust evidence base for the effective use of phytotherapy as a therapeutic option for women with PCOS. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - October 12, 2014 Category: Complementary Medicine Source Type: research

Monitoring in vitro antibacterial efficacy of 26 Indian spices against multidrug resistant urinary tract infecting bacteria
Conclusion The most effective and unique 16 spice plants recorded for the in vitro control of MDR uropathogens could further be pursued for the development of complementary and supplementary medicine against MDR bacteria. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - October 12, 2014 Category: Complementary Medicine Source Type: research

High-Rosmarinic Acid Spearmint Tea in the Management of Knee Osteoarthritis Symptoms
Journal of Medicinal Food , Vol. 0, No. 0. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - July 24, 2014 Category: Nutrition Tags: article Source Type: research

L-Carvone Induces p53, Caspase 3 Mediated Apoptosis and Inhibits the Migration of Breast Cancer Cell Lines.
Abstract A wide variety of natural compounds exists that possesses significant cytotoxic as well as chemopreventive activity through induction of apoptosis in cancer cells. The antiproliferative and apoptotic effect of L-carvone, an active component of spearmint (Mentha spicata) was studied on breast cancer (MCF 7 and MDA MB 231) and normal (MCF 10A) cell lines, and insight into its mechanism of action was attained. L-carvone inhibited proliferation of MCF 7 (IC50 1.2 mM) and MDA MB 231 cells (IC50 1.0 mM) and inhibited the migration of breast cancer cell lines. L-carvone induced apoptosis as observed by...
Source: Nutrition and Cancer - March 10, 2014 Category: Cancer & Oncology Authors: Patel PB, Thakkar VR Tags: Nutr Cancer Source Type: research

The Association between Chromaticity, Phenolics, Carotenoids, and In Vitro Antioxidant Activity of Frozen Fruit Pulp in Brazil: An Application of Chemometrics
Abstract A total of 19 Brazilian frozen pulps from the following fruits: açai (Euterpe oleracea), blackberry (Rubus sp.), cajá (Spondias mombin), cashew (Anacardium occidentale), cocoa (Theobroma cacao), coconut (Cocos nucifera), grape (Vitis sp.), graviola (Annona muricata), guava (Psidium guajava), papaya (Carica papaya), peach (Prunus persica), pineapple (Ananas comosus), pineapple and mint (A. comosus and Mentha spicata), red fruits (Rubus sp. and Fragaria sp.), seriguela (Spondias purpurea), strawberry (Fragaria sp.), tamarind (Tamarindus indica), umbu (Spondias tuberosa), and yellow passion fruit (Passiflora edulis...
Source: Journal of Food Science - February 18, 2014 Category: Food Science Authors: Acácio Antonio Ferreira Zielinski, Suelen Ávila, Vivian Ito, Alessandro Nogueira, Gilvan Wosiacki, Charles Windson Isidoro Haminiuk Tags: C: Food Chemistry Source Type: research

Comparison of the antibacterial activity of essential oils and extracts of medicinal and culinary herbs to investigate potential new treatments for irritable bowel syndrome
Conclusions: Many of the essential oils had antibacterial activity in the three assays, suggesting that they would be good candidates for testing in clinical trials. The observed antibacterial activity of ethanolic extracts of coriander, lemon balm and spearmint leaves suggests a mechanistic explanation for the efficacy of a mixture of coriander, lemon balm and mint extracts against IBS in a published clinical trial. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - November 28, 2013 Category: Complementary Medicine Authors: Aiysha ThompsonDilruba MeahNadia AhmedRebecca Conniff-JenkinsEmma ChilesheChris PhillipsTim ClaypoleDan FormanPaula Row Source Type: research

Antibacterial Effect of Mentha spicata Essential Oil on Listeria monocytogenes in Traditional Lighvan Cheese
AbstractListeria monocytogenes is a foodborne pathogen that is widespread in the environment. There are several reports on the isolation of L. monocytogenes from many types of cheeses. The aim of this study was to evaluate the antibacterial effect of Mentha spicata essential oil on L. monocytogenes in traditional Lighvan cheese. L. monocytogenes was added to the raw ewe's milk and M. spicata essential oil was subsequently mixed with the milk at concentrations of 0, 2 and 2.5%. After producing the cheese, sampling performed until 60 days. Results of this study showed that M. spicata essential oil at all concentrat...
Source: Journal of Food Safety - October 16, 2013 Category: Food Science Authors: Mir‐Hassan Moosavy, Saber Esmaeili, Ehsan Mostafavi Tags: Original Article Source Type: research