Quantification of l ‐carvone in toothpastes available on the Swedish market
ConclusionThe majority of toothpastes on the Swedish market contain l‐carvone, but the concentration hardly relates to the advertised flavour or labelled ingredients. It is hitherto unknown whether the found concentrations are sufficient for induction of contact allergy in individuals with healthy oral mucosa or in those with oral lichenoid lesions or other mucosal disease. (Source: Contact Dermatitis)
Source: Contact Dermatitis - May 19, 2017 Category: Dermatology Authors: Liv Kroona, Gunnar Warfvinge, Marl éne Isaksson, Camilla Ahlgren, Jakob Dahlin, Östen Sörensen, Magnus Bruze Tags: Original Article Source Type: research

Safety and tolerability of a dried aqueous spearmint extract
Publication date: Available online 7 March 2017 Source:Regulatory Toxicology and Pharmacology Author(s): Joanne A. Lasrado, Kristin M. Nieman, Brenda A. Fonseca, Kristen D. Sanoshy, Arianne L. Schild, Kelli A. Herrlinger Spearmint (Mentha spicata L.) and spearmint extracts are Generally Recognized as Safe (GRAS) for use as flavoring in beverages, pharmaceuticals, and confectionaries. Studies of spearmint extracts in humans and animals have reported conflicting results with respect to toxicity. Since the chemical composition of these extracts was not reported and the spearmint source material was different, the rele...
Source: Regulatory Toxicology and Pharmacology - March 7, 2017 Category: Toxicology Source Type: research

Safety and tolerability of a dried aqueous spearmint extract.
Abstract Spearmint (Mentha spicata L.) and spearmint extracts are Generally Recognized as Safe (GRAS) for use as flavoring in beverages, pharmaceuticals, and confectionaries. Studies of spearmint extracts in humans and animals have reported conflicting results with respect to toxicity. Since the chemical composition of these extracts was not reported and the spearmint source material was different, the relevance of these existing data to evaluating the risks associated with ingestion of a dried aqueous spearmint extract standardized to rosmarinic acid is not clear. Hence, the safety and tolerability of the...
Source: Regulatory Toxicology and Pharmacology : RTP - March 6, 2017 Category: Toxicology Authors: Lasrado JA, Nieman KM, Fonseca BA, Sanoshy KD, Schild AL, Herrlinger KA Tags: Regul Toxicol Pharmacol Source Type: research

Study of hypoglycemic, hypocholesterolemic and antioxidant activities of Iranian Mentha spicata ...
This study was conducted to evaluate the hypoglycemic, hypocholesterolemic and antioxidant properties of Mentha spicata (Labiateae) leaves aqueous extract (MSLA) in alloxan-induced diabetic rats. In this study, hyperglycemia was induced in male rats by intraperitoneal injection of alloxan monohydrate (150 mg/kg). The aqueous extract of M. spicata was orally administered at a dose of 300 mg/kg body weight to diabetic rats for 21 days and the effects were compared with glibenclamid (2 mg/kg). Fasting blood sugar (FBS), body weight, lipid profile and serum malondialdehyde (MDA) were monitored at 0, 7, 14 and 21 days after ind...
Source: Iranian Journal of Pharmaceutical Research - February 28, 2017 Category: Drugs & Pharmacology Source Type: research

Vegetative, physiological, nutritional and antioxidant behavior of spearmint (Mentha spicata L.) in response to different nitrogen supply in hydroponics
Publication date: Available online 12 February 2017 Source:Journal of Applied Research on Medicinal and Aromatic Plants Author(s): Antonios Chrysargyris, Erato Nikolaidou, Aristeidis Stamatakis, Nikos Tzortzakis Mints are regarded as one of the most important spices throughout the world with increased demands on cultivation under controlled environment. We conducted a study to evaluate the effects of different nitrogen levels (N: 150–175–200–225–250mg/L) on the morphological and biochemical characteristics of spearmint (Mentha spicata L.) in hydroponics. The results indicated that N levels affected plant grow...
Source: Journal of Applied Research on Medicinal and Aromatic Plants - February 18, 2017 Category: Complementary Medicine Source Type: research

Extraction of Essential Oils from Mentha Spicata L. (Labiatae) via Optimized Supercritical Carbon Dioxide Process
Publication date: Available online 11 February 2017 Source:The Journal of Supercritical Fluids Author(s): M. Shahsavarpour, M. Lashkarbolooki, Mohammad Javad Eftekhari, F. Esmaeilzadeh Spearmint oil known as aromatic volatile compound of plants are widely used in food industries. In the present study, supercritical carbon dioxide (SC-CO2) extraction is used to extract the essential oil from spearmint leaves. In this way, a series of extraction experiments are designed to investigate the effect of different operating conditions such as extraction pressure (85–120bar), extraction temperature (38–50°C), CO2 flow ra...
Source: The Journal of Supercritical Fluids - February 10, 2017 Category: Chemistry Source Type: research

Molecules, Vol. 22, Pages 263: A Comparative Analysis of the Chemical Composition, Anti-Inflammatory, and Antinociceptive Effects of the Essential Oils from Three Species of Mentha Cultivated in Romania
This work was aimed at correlating the chemotype of three Mentha species cultivated in Romania with an in vivo study of the anti-inflammatory and antinociceptive effects of essential oils. The selected species were Mentha piperita L. var. pallescens (white peppermint), Mentha spicata L. subsp. crispata (spearmint), and Mentha suaveolens Ehrh. (pineapple mint). Qualitative and quantitative analysis of the essential oils isolated from the selected Mentha species was performed by gas chromatography coupled with mass spectrometry (GC-MS). The anti-inflammatory activity of the essential oils was determined by the rat paw edema ...
Source: Molecules - February 9, 2017 Category: Chemistry Authors: Cristina Mogosan Oliviu Vostinaru Radu Oprean Codruta Heghes Lorena Filip Georgeta Balica Radu Moldovan Tags: Article Source Type: research

Study of hypoglycemic, hypocholesterolemic and antioxidant activities of Iranian Mentha spicata ...
This study was conducted to evaluate the hypoglycemic, hypocholesterolemic and antioxidant properties of Mentha spicata (Labiateae) leaves aqueous extract (MSLA) in alloxan-induced diabetic rats. In this study, hyperglycemia was induced in male rats by intraperitoneal injection of alloxan monohydrate (150 mg/kg). The aqueous extract of M. spicata was orally administered at a dose of 300 mg/kg body weight to diabetic rats for 21 days and the effects were compared with glibenclamid (2 mg/kg). Fasting blood sugar (FBS), body weight, lipid profile and serum malondialdehyde (MDA) were monitored at 0, 7, 14 and 21 days after ind...
Source: Iranian Journal of Pharmaceutical Research - January 27, 2017 Category: Drugs & Pharmacology Source Type: research

Mentha spicata as natural analgesia for treatment of pain in osteoarthritis patients.
Abstract Osteoarthritis, as the major cause of chronic musculoskeletal pain, impacts people aged 45 and above. The first line analgesic treatments have reported minimal short term effects. The use of essential oils as pain killer has increased, recently. Mentha spicata, or spearmint essential oil is famous due to its anti-flatulence effects, but one less known biological activity of spearmint is its analgesic activity. The aim of our study was to confirm the analgesic effects of M. spicata essential oil. In this review, we evaluated the articles on analgesic activities of M. spicata essential oil from diff...
Source: Complementary Therapies in Clinical Practice - January 22, 2017 Category: Complementary Medicine Authors: Mahboubi M Tags: Complement Ther Clin Pract Source Type: research

Identification and Quantitation of Potent Odorants in Spearmint Oils
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.6b04852 (Source: Journal of Agricultural and Food Chemistry)
Source: Journal of Agricultural and Food Chemistry - January 17, 2017 Category: Food Science Authors: Lauren E. Kelley and Keith R. Cadwallader Source Type: research

Advanced structure-activity relationships applied to Mentha spicata L. subsp. spicata essential oil compounds as AChE and NMDA ligands, in comparison with donepezil, galantamine and memantine - new approach in brain disorders pharmacology.
CONCLUSION: Our results point towards 1,8-cineole as a good candidate for NMDA antagonism, with a weaker AChE inhibitory effect. Our results may be useful in establishing new therapeutic strategies for neurological disorders. PMID: 28088901 [PubMed - as supplied by publisher] (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - January 12, 2017 Category: Drugs & Pharmacology Authors: Avram S, Maria M, Bagci E, Hritcu L, Borcan LC, Mihailescu D Tags: CNS Neurol Disord Drug Targets Source Type: research

Report on the Medicinal Use of Eleven Lamiaceae Species in Lebanon and Rationalization of Their Antimicrobial Potential by Examination of the Chemical Composition and Antimicrobial Activity of Their Essential Oils.
Authors: Khoury M, Stien D, Eparvier V, Ouaini N, El Beyrouthy M Abstract Many Lamiaceae species are consumed in the Lebanese cuisine as food or condiment and are largely used in the traditional medicine of Lebanon to treat various diseases, including microbial infections. In this article we report the traditional medicinal uses of eleven Lamiaceae species: Coridothymus capitatus L., Lavandula stoechas L., Lavandula angustifolia Mill., Mentha spicata L. subsp. condensata, Origanum syriacum L., Rosmarinus officinalis, Salvia fruticosa Miller., Satureja cuneifolia Ten., Satureja thymbra L., Thymbra spicata L...
Source: Evidence-based Complementary and Alternative Medicine - January 7, 2017 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Evidence of biological activity of Mentha species extracts on apoptotic and autophagic targets on murine RAW264.7 and human U937 monocytic cells.
CONCLUSIONS: The cytotoxic profiles depend on the extracts considered; MS extract showed the strong activity. However, all the mint extracts studied interact with the apoptotic and autophagic pathways at elevated concentrations. PMID: 27927076 [PubMed - in process] (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - December 10, 2016 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research

Laboratory Comparison of the Anti-Bacterial Effects of Spearmint Extract and Hypochlorite Sodium on Enterococcus Faecalis Bacteria
Conclusions:Considering the limitations of an experimental study, it seems that spearmint extract does not have any anti-bacterial effect against Enterococcus faecalis bacteria, in contrast to hypochlorite sodium 5.25%.Key words:Hypochlorite Sodium, Spearmint Extract, Root Canal Irrigation, Enterococcus faecalis (Source: Journal of Dental Biomaterials)
Source: Journal of Dental Biomaterials - November 29, 2016 Category: Dentistry Source Type: research

In vitro study of the antifungal activity of essential oils obtained from Mentha spicata, Thymus vulgaris and Laurus nobilis.
Authors: Houicher A, Hechachna H, Teldji H, Ozogul F Abstract The aim of this study was to determine the antifungal activity of the essential oils isolated from three aromatic plants against 13 filamentous fungal strains. The major constituents of Mentha spicata, Thymus vulgaris, and Laurus nobilis essential oils were carvone (52.2%), linalool (78.1%), and 1,8-cineole (45.6%), respectively. M. spicata essential oil exhibited the strongest activity against all tested fungi in which Fusarium graminearum, F.moniliforme, and Penicillium expansum were the most sensitive to mint oil with lower minimal inhibitory...
Source: Recent Patents on Food, Nutrition and Agriculture - October 6, 2016 Category: Food Science Tags: Recent Pat Food Nutr Agric Source Type: research