Evidence Mapping of Interactions on Concomitant Use of Traditional Chinese Medicine and Platinum-based Chemotherapy: A Scoping Review Protocol
This study aims to update the current knowledge on herbal-drug interactions of the commonly used platinum-based chemotherapy (PtC) in cancer patients.MethodsSystemic searches will perform on online databases (English and Chinese) to identify papers from inception until December 2019 for inclusion into the review. The search strategy will be following PRISMA Scoping Reviews Checklist as a quality assurance step. All records retrieved will be screened by 2 independent reviewers. The preclinical studies and clinical studies that involves in assessing the concurrent use of CHM and PtC will be considered. The Preferred Reportin...
Source: Integrative Medicine Research - February 15, 2020 Category: Complementary Medicine Source Type: research

Herbal medicine (Jogyeongseongjang decoction) for precocious puberty girls: a retrospective study
Publication date: Available online 13 February 2020Source: Integrative Medicine ResearchAuthor(s): Soo Bo Shim, Kyu Hee Choi, Seung Yong Lee, Jae Jun Lee, Min Seok Bu, Ju Ah Lee, In Chul Jung, Yang Chun Park, Seung Chan Park, Hye Lim Lee (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - February 15, 2020 Category: Complementary Medicine Source Type: research

Novel statistical approach offers new way to investigate the uses of acupuncture points
Publication date: Available online 1 February 2020Source: Integrative Medicine ResearchAuthor(s): Stephen Birch, Terje Alraek (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - February 1, 2020 Category: Complementary Medicine Source Type: research

The constant progression of Integrative Medicine Research
Publication date: Available online 27 January 2020Source: Integrative Medicine ResearchAuthor(s): Myeong Soo Lee (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - January 28, 2020 Category: Complementary Medicine Source Type: research

Development of Integrative Medicine Therapy for Gastrointestinal Autoimmune Diseases: A study protocol for a registry study
This study is a registry study of patients diagnosed with gastrointestinal AD. Subjects who voluntarily sign a written consent form after receiving a sufficient explanation will be assessed for compliance with the inclusion and exclusion criteria through a screening process on their first visit. A total of 35 subjects will be recruited; 15 will be assigned to the patient group, 10 to the control group, 8 to the caregiver group, and 2 to the medical staff group. The clinical information of the subjects will be evaluated through statistical analyses. As this study is a registry study, it will not test specific hypotheses.Dis...
Source: Integrative Medicine Research - January 28, 2020 Category: Complementary Medicine Source Type: research

Complementary therapy for female infertility: protocol for an overview of systematic reviews
ConclusionThis overview will apprise the overall quality and evidence of the outcomes of SRs of complementary therapy for female infertility.Study registrationResearch Registry UIN (reviewregistry769) (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - January 24, 2020 Category: Complementary Medicine Source Type: research

Herbal medicines (Eunkyosan and Samsoeum) for treating the common cold: a protocol for a randomized, placebo-controlled, multicenter clinical trial
This study is a randomized, patient-assessor blind, controlled, parallel, and multicenter clinical trial. A total of 375 participants diagnosed with the common cold were enrolled via four hospitals. The common cold patients will take a daily dose of Eunkyosan or Samsoeum or a placebo, three times a day for eight days. The primary outcome is the change in total Wisconsin Upper Respiratory Symptom Scale-21-Korean (WURSS-21-K) score between baseline and six days. The secondary outcome includes the visual analogue scale (VAS). Safety is evaluated and adverse events are assessed throughout the trial. Written informed consent wi...
Source: Integrative Medicine Research - January 23, 2020 Category: Complementary Medicine Source Type: research

Clinical trial registration, and publication in acupuncture studies: a systematic review
ConclusionsThe substantial increase of registrations by China, the Republic of Korea, Iran, Brazil, Japan was observed which may be attributed to improved awareness of the CONSORT statement. However, the fully published papers rate is low at 10%. The publication of results of acupuncture clinical trials should also be rigorously mandated. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - January 22, 2020 Category: Complementary Medicine Source Type: research

Statistical inference of acupoint specificity: Forward and reverse inference
ConclusionsThe selection of an acupoint for a particular disease does not imply that the acupoint has specific indications for that disease. We should consider inferring the specificity of acupoint indication from clinical observations. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - January 22, 2020 Category: Complementary Medicine Source Type: research

Effects of yoga breathing practice on heart rate variability in healthy adolescents: a randomized controlled trial
This study was conducted among healthy adolescents to assess the effects of a yoga breathing practice (Bhramari pranayama, Bhr.P) towards cardiac autonomic function using heart rate variability (HRV) parameters.MethodsOf the 730 eligible subjects screened, 520 healthy adolescents who met the inclusion and exclusion criteria were randomly assigned to either yoga breathing group (n = 260) or control group (n = 260). The yoga breathing group practiced Bhr.P. five days a week for a duration of six months while the control group continued with their daily routine without any intervention. Outcome mea...
Source: Integrative Medicine Research - January 22, 2020 Category: Complementary Medicine Source Type: research

Autonomic nervous function in patients with atopic dermatitis and its implications for acupuncture treatment: a retrospective study
Publication date: Available online 20 January 2020Source: Integrative Medicine ResearchAuthor(s): Min Hee Kim, Chunhoo Cheon, Hae Jeong Nam, Bonghyun Kim, Inhwa Choi (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - January 22, 2020 Category: Complementary Medicine Source Type: research

Horticultural therapy program for improving emotional well-being of elementary school students: an observational study
ConclusionsThis study may show a potential of horticultural therapy for psycho-emotional health of children. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - January 22, 2020 Category: Complementary Medicine Source Type: research

Is Acupuncture Dose Dependent? Ramifications of acupuncture treatment dose within clinical practice and trials
Publication date: Available online 20 January 2020Source: Integrative Medicine ResearchAuthor(s): Matthew Bauer, John Leslie McDonald, Natalie SaundersAbstractProblems in acupuncture research associated with the limitations of randomized placebo-controlled trials have been discussed for decades. However, there has been little discussion around acupuncture trial design to optimize the chances of acupuncture treatment achieving maximum therapeutic benefit (MTB). While there are numerous factors in clinical trial design which can influence clinical outcomes, there is emerging evidence to suggest that acupuncture treatment dos...
Source: Integrative Medicine Research - January 22, 2020 Category: Complementary Medicine Source Type: research

The Regulation of Complementary and Alternative Medicine Professions in Ontario, Canada
ConclusionUnregulated CAM professions may increase their likelihood of becoming regulated if they: (1) gain popularity/strong support from patients or the general public, (2) organize themselves sufficiently that they pose a direct threat to one or more scopes of practice desirable by the DSIs and/or (3) are willing to adopt standards in education, training, and ethics that may [initially] reduce their scope of practice or profession’s membership or slow their profession’s growth. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - January 18, 2020 Category: Complementary Medicine Source Type: research

A qualitative study of classical Chinese medicine in community health focusing on self-care: practitioner and staff perspectives
ConclusionThis study highlights the importance of accessibility, integration, networking, secure funding and team unity in the context of community health program delivery, as well as noting a diversity of practice among Chinese medicine practitioners. CCM concepts may hold potential for integration into community health, however, further research is warranted. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - January 18, 2020 Category: Complementary Medicine Source Type: research

2019 Reviewer Acknowledgement
Publication date: December 2019Source: Integrative Medicine Research, Volume 8, Issue 4Author(s): (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - December 21, 2019 Category: Complementary Medicine Source Type: research

Editorial Board
Publication date: December 2019Source: Integrative Medicine Research, Volume 8, Issue 4Author(s): (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - December 21, 2019 Category: Complementary Medicine Source Type: research

Contents
Publication date: December 2019Source: Integrative Medicine Research, Volume 8, Issue 4Author(s): (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - December 21, 2019 Category: Complementary Medicine Source Type: research

Japanese government research grants for Kampo medicine: an overview of 10 years (1997–2017)
ConclusionsThe Japanese government research grants from 1973 to 2017 indicate that research on Kampo medicine which barely had any interest previously, was revived in the 2000s. In particular, it increased sharply in the 2010s, and the research fields were relatively diverse. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - December 21, 2019 Category: Complementary Medicine Source Type: research

Recovery from hepatitis A after Korean medicine-based treatment: a case report
Publication date: December 2019Source: Integrative Medicine Research, Volume 8, Issue 4Author(s): Chan-Ran Park, Gayoung Lee, Chang-Gue Son, Jung-Hyo Cho, Nam-Hun LeeAbstractBackgroundMany studies reported that Korean medicine (KM) is effective for treating liver disease, including hepatitis A. However, KM, specifically with herbal medicine (Chungganplus, CGP) has not been reported yet. We aimed to report a patient with hepatitis A who was treated with KM including CGP, acupuncture, and moxibustion for 12 days.MethodsA 39-year-old man with hepatitis A who was hospitalized for 12 days after being admitted to our hospital wi...
Source: Integrative Medicine Research - December 21, 2019 Category: Complementary Medicine Source Type: research

Acupuncture in Italy: State of the Art
Publication date: Available online 17 December 2019Source: Integrative Medicine ResearchAuthor(s): Carlo Maria Giovanardi, Umberto Mazzanti, Alessandra Poini (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - December 19, 2019 Category: Complementary Medicine Source Type: research

Trend of clinical trials in Persian medicine: A decade of endeavours
Publication date: Available online 6 December 2019Source: Integrative Medicine ResearchAuthor(s): Mehdi Pasalar, Hossein Molavi Vardanjani (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - December 7, 2019 Category: Complementary Medicine Source Type: research

Japanese government research grants for Kampo medicine: aAn overview of 10 years (1997–2017)
ConclusionsAfter analyzing the Japanese government research grants from 1973 to 2017, research on Kampo medicine, which barely had any interest previously, was revived in the 2000s. In particular, it increased sharply in the 2010s, and the research fields were relatively diverse. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 29, 2019 Category: Complementary Medicine Source Type: research

Acupuncture plus night splint for quality of life and disability in patients with carpal tunnel syndrome: a randomized controlled trial
ConclusionThe effect of acupuncture plus night splinting may show significant reduction on pain but failed to show significant differences compared with night splinting in patients with CTS. Further studies with larger sample size may confirm the findings. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 27, 2019 Category: Complementary Medicine Source Type: research

Corrigendum to “Molecular mechanisms of anticancer activity of Deoxyelephantopin in cancer cells” [Kabeer, F.A.; Rajalekshmi, D.S.; Nair, M.S.; Prathapan, R. Molecular mechanisms of anticancer activity of deoxyelephantopin in cancer cells. Integr Med Res] 2017, 6, 190–206. https://doi.org/10.1016/j.imr.2017.03.004
Publication date: December 2019Source: Integrative Medicine Research, Volume 8, Issue 4Author(s): Farha Arakkaveettil Kabeer, Dhanya Sethumadhavan Rajalekshmi, Mangalam Sivasankaran Nair, Remani Prathapan (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 27, 2019 Category: Complementary Medicine Source Type: research

Exploring the effects of expert-led qigong and self-practice qigong on blood pressure
Publication date: December 2019Source: Integrative Medicine Research, Volume 8, Issue 4Author(s): Ji-Eun Park, Chang-Sop Yang, So-Young Jung, Ae-Ran Kim, Minhee Lee, Sun-Mi Choi (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 24, 2019 Category: Complementary Medicine Source Type: research

Overview of Cochrane reviews on Chinese herbal medicine for stroke
ConclusionThis overview reveals the potential efficacy of herbal medicines for the treatment of stroke in terms of neurological deficit improvement. However, due to the high risk of bias in the reviews’ studies, an affirmative conclusion for the recommendation of herbal medicine for clinical practice could not be drawn. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 23, 2019 Category: Complementary Medicine Source Type: research

Japanese government research grants for Kampo medicine: an overview of 10 years (1997-2017)
ConclusionsAfter analyzing the Japanese government research grants from 1973 to 2017, research on Kampo medicine, which barely had any interest previously, was revived in the 2000s. In particular, it increased sharply in the 2010s, and the research fields were relatively diverse. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 15, 2019 Category: Complementary Medicine Source Type: research

Effect of one time coffee fragrance inhalation on working memory, mood, and salivary cortisol level in healthy young volunteers: a randomized placebo controlled trial
ConclusionsOne time of coffee fragrance inhalation may enhance working memory and stimulates alertness. However, inhaling coffee fragrance does not reduce stress or modulate autonomic response to stress. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 15, 2019 Category: Complementary Medicine Source Type: research

Effects of a chattering teeth training oral appliance for working memory improvement in healthy volunteers: a cross-over randomized trial
DiscussionThis protocol proposes the rationale and method for the use of an intraoral appliance for working memory improvement. If the oral appliance demonstrates better feasibility for working memory improvement compared with chewing gum, a large scale study will be needed to investigate the effectiveness of the device on populations who require memory improvement. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 15, 2019 Category: Complementary Medicine Source Type: research

Acupuncture plus night sprint for quality of life and disability in patients with carpal tunnel syndrome: a randomized controlled trial
ConclusionThe effect of acupuncture on pain combine night splinting has a better effect on pain in the treatment of CTS than that of the only splinting. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 14, 2019 Category: Complementary Medicine Source Type: research

Effect of expert-lead qigong and home qigong on blood pressure: A pilot study
Publication date: Available online 12 November 2019Source: Integrative Medicine ResearchAuthor(s): Ji-Eun Park, Chang-Sop Yang, So-Young Jung, Ae-Ran Kim, Minhee Lee, Sun-Mi Choi (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 14, 2019 Category: Complementary Medicine Source Type: research

Minimisation of variations in locating an acupuncture point using a laser-device
ConclusionsOur findings suggest that direct measurement of the acupoint location using a laser device can reduce variations in locating points. Laser-assisted tools will help practitioners locate the acupoints more accurately and should be considered as standard practice, especially in acupuncture research and education. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 14, 2019 Category: Complementary Medicine Source Type: research

Recovery from Hepatitis A after Korean medicine-based treatment : A case report
Publication date: Available online 7 November 2019Source: Integrative Medicine ResearchAuthor(s): Chan-Ran Park, Gayoung Lee, Chang-Gue Son, Jung-Hyo Cho, Nam-Hun LeeAbstractBackgroundMany studies reported that Korean medicine (KM) is effective for treating liver disease, including hepatitis A. However, KM, specifically with herbal medicine (Chungganplus, CGP) has not been reported yet. We aimed to report a patient with hepatitis A who was treated with KM including CGP, acupuncture, and moxibustion for 12 days.MethodsA 39-year-old man with hepatitis A who was hospitalized for 12 days after being admitted to our hospital wi...
Source: Integrative Medicine Research - November 7, 2019 Category: Complementary Medicine Source Type: research

Buddhist meditation for vascular function: A narrative review
ConclusionThis paper presents brief overview of clinical outcomes of complementary therapeutic approach of Buddhist meditation in vascular function. In future, well-structured systematic reviews are essential to report specificity of Buddhist mindfulness-based approach on vascular function, blood pressure and other cardiovascular risk factors. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - November 5, 2019 Category: Complementary Medicine Source Type: research

Research-related attitudes among Chinese medicine students at a Canadian college: A mixed-methods study
ConclusionResearch-related curricular interventions in the Chinese medicine field should directly address model validity, as it is of significant interest to a majority of students. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - October 19, 2019 Category: Complementary Medicine Source Type: research

Complementary and alternative medicine for treating amyotrophic lateral sclerosis: A narrative review
ConclusionThis review shows that CAM may be useful for ALS treatment, but more evidence regarding the efficacy and molecular mechanisms is required to establish CAM as a good therapy for the treatment of ALS patients. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - October 19, 2019 Category: Complementary Medicine Source Type: research

Effects of a Gochi (chattering teeth training) device for working memory improvement in healthy volunteers: a cross-over randomized trial
DiscussionThis protocol proposes the rationale and method for the use of an intraoral device for working memory improvement. If the No-Sick Exerciser® demonstrates better feasibility for working memory improvement compared with chewing gum, a large scale study will be needed to investigate the effectiveness of the device on populations who require memory improvement. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - October 15, 2019 Category: Complementary Medicine Source Type: research

Editorial Board
Publication date: September 2019Source: Integrative Medicine Research, Volume 8, Issue 3Author(s): (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - September 26, 2019 Category: Complementary Medicine Source Type: research

Contents
Publication date: September 2019Source: Integrative Medicine Research, Volume 8, Issue 3Author(s): (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - September 26, 2019 Category: Complementary Medicine Source Type: research

Ethnomedicine of Tetun ethnic people in West Timor Indonesia: philosophy and practice in the treatment of malaria
ConclusionEthnomedicine practice of Tetun people on malaria is proven to contain scientific truth, although it is built on the basis of concepts that are different or even contrary to the true etiology of malaria. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - September 26, 2019 Category: Complementary Medicine Source Type: research

Herbal formula (Danggui Beimu Kushen Wan) for prostate disorders: A systematic review of classical literature
ConclusionIncluded classic literature has provided fundamental evidence for the management of difficult urination in female and male. Further studies should investigate its mechanisms of actions for difficult urination related conditions, such as prostate disorders. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - September 2, 2019 Category: Complementary Medicine Source Type: research

Perceptions of using herbal medicines for managing menopausal symptoms: A web-based survey of Korean medicine doctors
Conclusion: The results of this survey may provide information about doctor’s perceptions on using herbal medicines to manage patient’s menopausal symptoms. Future studies should be done with a larger sample size to overcome the limitation of this study and to examine how KM is used for treating menopausal symptoms in clinical practice. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - August 30, 2019 Category: Complementary Medicine Source Type: research

Complementary and alternative medicine for treating amyotrophic lateral sclerosis : a narrative review
Publication date: Available online 29 August 2019Source: Integrative Medicine ResearchAuthor(s): Mudan Cai, Eun Jin YangAbstractAmyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease that is characterized by selective motor neuron cell death in the motor cortex, brainstem, and spinal cord. Two drugs for ALS, riluzole and edaravone, have been approved by FDA for the treatment of ALS patients. However, they have many side effects, and riluzole extends the patient’s life by only 2–3 months. Therefore, ALS patients seek an effective therapy for treating the symptoms or delaying the progression of A...
Source: Integrative Medicine Research - August 30, 2019 Category: Complementary Medicine Source Type: research

Clinical Application of Single Acupoint (HT7)
Publication date: Available online 30 August 2019Source: Integrative Medicine ResearchAuthor(s): Chang-Gue Son (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - August 30, 2019 Category: Complementary Medicine Source Type: research

Anti-inflammatory and analgesic potential of Tamarindus indica Linn. (Fabaceae): a narrative review
Publication date: September 2019Source: Integrative Medicine Research, Volume 8, Issue 3Author(s): Richard Komakech, Yong-goo Kim, Gilbert Motlalepula Matsabisa, Youngmin KangAbstractChronic inflammation is one of the causes of a number of non-infectious diseases in the world. Over the years, Tamarindus indica has played fundamental roles in traditional medicine as an anti-inflammatory and analgesic drug. It is a commercialized biocompatible medicinal plant species with a wide range of therapeutic window and with suggested LD50 greater than 5000 mg kg−1 body weight when administered to the Wistar rats. This...
Source: Integrative Medicine Research - August 15, 2019 Category: Complementary Medicine Source Type: research

An examination of naturopathic treatment of non-specific gastrointestinal complaints: comparative analysis of two cases
ConclusionsThe holistic and individualised approach core to naturopathic medicine practice is also informed by traditional methods, research evidence and the pragmatic needs of the patient. The emphasis within naturopathic treatment approaches on dietary changes and lifestyle prescription alongside other ingestive therapies such as herbal and nutritional medicine underscores the need for clinical research designs which support evaluation of complex interventions in real-world settings. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - August 14, 2019 Category: Complementary Medicine Source Type: research

Acupuncture using pattern-identification for the treatment of insomnia disorder: A systematic review and meta-analysis of randomized controlled trials
Publication date: Available online 13 August 2019Source: Integrative Medicine ResearchAuthor(s): Sang-Ho Kim, Jin-Hyung Jeong, Jung-Hwa Lim, Bo-Kyung KimABSTRACTBackgroundInsomnia symptoms are common, affecting almost 30% of the population of the population. many use medications that may be ineffective and cause substantial harm. In complementary and alternative medicine, acupuncture is widely used to manage mental health problems. Acupuncture therapy emphasizes individualized treatment according to TCM pattern diagnosis. Although there are some systematic reviews that acupuncture has the benefit for insomnia, there is no ...
Source: Integrative Medicine Research - August 14, 2019 Category: Complementary Medicine Source Type: research

Herbal medicine (Hepad) prevents dopaminergic neuronal death in the rat MPTP model of Parkinson’s disease
ConclusionsHepad S1 exerts antioxidant and neuroprotective effects on neurons of the substantia nigra in a rodent model of PD. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - August 6, 2019 Category: Complementary Medicine Source Type: research

A comparison of attitudes towards complementary and alternative medicine between psychologists in Australia and Indonesia: A short report
ConclusionAustralian and Indonesian psychologists reported ambivalent attitudes towards CAM that might be reduced with clear regulation of CAM integration into psychological services from the government and professional organizations. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - July 30, 2019 Category: Complementary Medicine Source Type: research