The Mountain Model of Hyponatremia
“The Mountain Model of Hyponatremia” is an educational project byJoel Topf and me.Imagine this is the clinical scenario of severe hyponatremia:You are driving in a car at the top of a mountain. (The top of the mountain is the low sodium level.) There is a forest fire behind you. (The fire represents brain swelling and seizures if the sodium level drops much lower.)Your goal is to drive safely to the bottom of the mountain. (The bottom of the mountain is a normal sodium level.)But, to be safe, you must follow the “sodium speed limit”: a rise in sodium of 8 every 24 hours. (If you exceed this “sodiu...
Source: Kidney Notes - February 24, 2023 Category: Urology & Nephrology Authors: Test Source Type: blogs
How To Live A Longer Life By Maintaining Optimal Sodium Levels
The study sheds light on the critical link between sodium levels and aging, with potentially life-altering implications. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - February 2, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Nutrition Source Type: blogs
Fight Aging! Newsletter, January 23rd 2023
This study explored the association between tap drinking water and longevity in Cilento, Italy, to understand whether trace elements in local drinking water may have an influence on old, nonagenarian, and centenarian people and promote their health and longevity.
Data on population and water sources were collected through the National Demographic Statistics, the Cilento Municipal Archives, and the Cilento Integrated Water Service. Ordinary least squares (OLS) regression and a geographically weight regression (GWR) model were used to study the spatial relationship between the explanatory and outcome variables of long...
Source: Fight Aging! - January 22, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Artificial Neuron Uses Ions Like the Real Thing
Researchers at Linköping University in Sweden have developed artificial neurons that demonstrate 15 of the 20 characteristics of biological neural cells and can communicate with natural neurons in the body. The researchers call their device the “conductance-based organic electrochemical neuron,” or c-OECN, and it is based on materials that can conduct a negative charge, including organic electrochemical transistors and n-type conducting polymers. By printing thousands of such transistors on a flexible substrate, the researchers have been able to create artificial neurons. The device uses ions to control the fl...
Source: Medgadget - January 19, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Neurology Neurosurgery liu_universitet Source Type: blogs
Exploring Correlations Between Trace Elements in Drinking Water and Longevity
This study explored the association between tap drinking water and longevity in Cilento, Italy, to understand whether trace elements in local drinking water may have an influence on old, nonagenarian, and centenarian people and promote their health and longevity.
Data on population and water sources were collected through the National Demographic Statistics, the Cilento Municipal Archives, and the Cilento Integrated Water Service. Ordinary least squares (OLS) regression and a geographically weight regression (GWR) model were used to study the spatial relationship between the explanatory and outcome variables of long...
Source: Fight Aging! - January 19, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, January 16th 2023
Conclusions
Implanted Hair Follicle Cells Produce Remodeling of Scar Tissue
Assessment of Somatic Mosaicism as a Biomarker of Aging
The Gut Microbiome of Centenarians
https://www.fightaging.org/archives/2023/01/the-gut-microbiome-of-centenarians/
The state of the gut microbiome is arguably as influential on health as exercise. Various microbial species present in the gut produce beneficial metabolites, such as butyrate, or harmful metabolites, such as isoamylamine, or can provoke chronic inflammation in a variety of ways. An individual can have a better or worse microbiome, assessing these and other...
Source: Fight Aging! - January 15, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Dehydration as an Accelerator of Aging
In this study, we report on serum sodium in the upper part of the normal range being a risk factor for accelerated aging. In the Atherosclerosis Risk in Communities (ARIC) study, odds to be biologically older than chronological age was increased in the study participants whose serum sodium exceeded 142 mmol/l, reaching 50% increased odds at sodium levels exceeding 144 mmol/l. Such elevated biological age at middle age (47-68 years) translates into an approximate 20% increased risk of premature mortality at sodium levels greater than 144 mmol/l and increased risk to develop chronic diseases, that was already evident at s...
Source: Fight Aging! - January 9, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Top 8 Most Controversial Stories About Medical Innovations
I spend my days monitoring progress, analysing new trends, and learning about spectacular new initiatives. Needless to say: not just me, but the whole team of The Medical Futurist is fascinated by what we learn. And then sometimes there is a story that just melts the fuses at one or more team members – and our readers.
Below I picked 8 of our favourite controversial stories from – almost exclusively – this year. It’s important to note that controversial doesn’t equal bad/useless. Sometimes it’s just not widely accepted (yet) and so exotic that they can surely provide a unique talking point at a...
Source: The Medical Futurist - December 13, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF 3d printing AI artificial intelligence bioprinting digital health CRISPR designer baby designer babies robotics in healthcare assisted dying DIY blood draw DIY blood test medical innovation deepfake Source Type: blogs
Independent Medicines and Medical Devices Safety Review: update report on government implementation
Department of Health and Social Care - This implementation report provides an update on the government ’s progress to implement the2021 government response to the 2020Independent Medicines and Medical Devices Safety Review and improve patient safety. It sets out the steps the government is taking to implement the accepted strategic recommendations and actions for improvement and provides more detail on the government ’s work on sodium valproate and pelvic mesh.ReportMore detail (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - December 13, 2022 Category: UK Health Authors: The King ' s Fund Library Tags: Patient safety Source Type: blogs
Rapid Diagnosis: Vomiting Blood
The dispatcher reports that the patient is vomiting blood. Hemataemesis if you want to be technical about it. It could be a whole bunch of things right? … Well yes it could. Before you e-mail me to say that you can’t believe I missed Bolivian Hemorrhagic Fever, here’s one web site that lists 113 possibilities.
But if you want to play the numbers, it’s going to be one of four things. And if you want to play “stump your partner” you can narrow it down quite a bit based on your patients age and disposition.
There are four things that tend to cause a person to vomit blood. Before you click on the little ...
Source: The EMT Spot - November 14, 2022 Category: Emergency Medicine Authors: Steve Whitehead Tags: EMT Source Type: blogs
Fight Aging! Newsletter, November 14th 2022
In this study, we show that TXNIP is vital for the cell fate choice when cells are challenged by various stress signals. Furthermore, prolonged IGF1 treatment leads to the establishment of a premature senescence phenotype characterized by a unique senescence network signature. Combined IGF1/TXNIP-induced premature senescence can be associated with a typical secretory inflammatory phenotype that is mediated by STAT3/IL-1A signaling. Finally, these mechanistic insights might help with the understanding of basic aspects of IGF1-related pathologies in the clinical setting.
Investigating the Ability of Type 2 Diabetes...
Source: Fight Aging! - November 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
How To Lower Diastolic Blood Pressure Through Minor Lifestyle Changes?
ConclusionWhat Is Diastolic Blood Pressure?
Diastolic blood pressure is the pressure in arteries during the resting phase of a heart. These range below 120 mmHg in a healthy human, whereas 120-129 is an elevated stage, and anything in between 130-139 mmHg or above is considered hypertension.
Why Choose The Drug-Free Approach To Manage Blood Health?
Managing blood health without using medicines is best for early-stage patients. There are a few reasons why one should choose a drug-free approach.
First, drug-free approaches are often more effective in the long run. Second, these methods tend to have fewer side eff...
Source: The EMT Spot - November 11, 2022 Category: Emergency Medicine Authors: Michael Kutryk Tags: Guides Blood Pressure Source Type: blogs
Wrong Medicine
Some of the stacks of trip reports were nearing four feet high and they filled the musty closet. Dividing them up, we started sorting through them in earnest. The dates indicated that the calls had been run between 1972 and 1978. Most of the narratives were as brief as the treatment lists.
Hall Ambulance’s station one was an older house in an early residential area of Bakersfield, California. It had been, at one time, the residence of the company’s owner, Harvey Hall. In the early days of the ambulance service, Harvey had both lived in the home and run his fledgling ambulance service out of it.
One of the crews s...
Source: The EMT Spot - November 10, 2022 Category: Emergency Medicine Authors: Steve Whitehead Tags: EMT Source Type: blogs
The Med List: ACE Inhibitors
Today I’m starting a new series called The Med List. Once or twice a month, I’d like take a closer look at a single class of home medications and explore the medical implications for our patients who take these meds.
The patient’s medications list holds a wealth of information. Prescribed medications tell us about the patient’s medical history. They also give us clues to the patient’s possible current condition and presentation. Some medicines can better explain the clinical picture in front of us and others can be red flags regarding treatment options and the patients likely response.
Let’s kic...
Source: The EMT Spot - November 9, 2022 Category: Emergency Medicine Authors: Steve Whitehead Tags: EMT Source Type: blogs
High Blood Pressure Can Lead to Kidney Damage
Conclusion
A potential outcome of hypertension is damage to blood vessels and organs such as the kidneys. In addition, a delay in receiving treatment increases the risk of waste fluid build-up, which elevates the chance of complications and, ultimately, renal failure.
If your doctor has diagnosed you with hypertension, you might be recommended adaptations to your lifestyle and medications. It’s vital to take prescription drugs as indicated and attend follow-ups as scheduled to check blood pressure.
References
“High Blood Pressure & Kidney Disease.” National Institute of Diabetes and Digestive and Kidney...
Source: The EMT Spot - November 8, 2022 Category: Emergency Medicine Authors: Michael Kutryk Tags: Guides Blood Pressure Source Type: blogs
