A very special protein synthesis machinery
(ETH Zurich) Sleeping sickness-causing parasites contain an unusual protein synthesis machinery. A team of researchers from ETH Zurich and the University of Berne resolved its very special structure for the first time. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 13, 2018 Category: Biology Source Type: news
Sleeping sickness: Pathogens camouflage themselves with sugar
(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) It has long been known that the pathogens causing sleeping sickness evade the immune system by exchanging their surface proteins. But now scientists at the German Cancer Research Center have found an additional parasite strategy to escape the immune system: they confuse the defense system with sugar. The sugar chains on the coat protein prevent the binding of protective antibodies and thus increase the pathogenic properties of the unicellular pathogens. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 9, 2018 Category: Biology Source Type: news
Stopping a tiny -- and deadly -- fly in its tracks
(Brigham Young University) New research presents a technique that could help treat African sleeping sickness, which impacts millions in sub-Saharan Africa and -- in its late stages -- can be fatal. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 5, 2018 Category: Infectious Diseases Source Type: news
Angola:21 Positive Cases of Sleeping Sickness in Banga
[ANGOP] Banga -Twenty - one positive cases of sleeping sickness were diagnosed in the last two weeks in the municipality of Banga, Cuanza Norte province, during the prospecting campaign held by the Provincial Department of the Institute of Combat and Control of Trypanosomiasis (Icct). (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 8, 2018 Category: African Health Source Type: news
Angola:Luanda Hosts 3rd Cross-Border Meeting On Sleeping Sickness
[ANGOP] Luanda -Angolan capital, Luanda, is the venue of the 3rd Cross-Border Meeting on Sleeping Sickness, trypanosomiasis, on 8, 9 May, Angop has learnt. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 4, 2018 Category: African Health Source Type: news
Aksoy Labs combats the tsetse fly to protect Africa from sleeping sickness
Yale professor of Serap Aksoy ’s work to combat sleeping sickness in Africa has included mapping the genome of the tsetse fly and developing student workshops. (Source: Yale Science and Health News)
Source: Yale Science and Health News - February 15, 2018 Category: Universities & Medical Training Source Type: news
Sanofi and partner seek European Medicines Agency review for sleep sickness product
PARIS (Reuters) - French healthcare group Sanofi, along with its business partner, has asked the European Medicines Agency (EMA) to review the fexinidazole product for the treatment of sleeping sickness, the company said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - January 31, 2018 Category: Consumer Health News Tags: healthNews Source Type: news
Nigeria:'Nigeria Loses U.S.$70 Million Yearly to Sleeping Sickness'
[Guardian] Nigeria loses an estimated $70m yearly to sleeping sickness and as such, the Federal Governments should strive to eradicate tsetse flies and transpanomiases (T and T) that transmit the disease. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 29, 2018 Category: African Health Source Type: news
Study: Sleeping sickness not just a sleeping disorder
(UT Southwestern Medical Center) An international study from the O'Donnell Brain Institute shows one of Africa's most lethal diseases is actually a circadian rhythm disorder caused by the acceleration of biological clocks controlling a range of vital functions besides sleep. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 4, 2018 Category: International Medicine & Public Health Source Type: news
WATCH: The Battle Against Sleeping Sickness
HuffPost traveled to Congo to document efforts to fight this deadly disease. (Source: Science - The Huffington Post)
Source: Science - The Huffington Post - October 31, 2017 Category: Science Source Type: news
Discovery of a potential therapeutic target to combat trypanosomes
(CNRS) Using cryo-electron microscopy, French researchers at the Institut de Biologie Mol é culaire et Cellulaire (CNRS/Universit é de Strasbourg) have analyzed the structure of trypanosomes parasites in details and revealed one of their potential weak points, which has remained undetected until now. This discovery opens the path to the development of new safer therapies that are less toxic and more specific against trypanosomes, the parasites causing the Chagas disease and the African sleeping sickness. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 26, 2017 Category: Biology Source Type: news
Genomic screening helps doctors target girl's cancer
(Medical University of South Carolina) Two-year-old Victoria Thompson is part of the national precision medicine trial Peds PLAN through MUSC Children's Health for children with high-risk neuroblastoma. She's also receiving DFMO, a drug normally used to treat African sleeping sickness that may help keep high-risk neuroblastoma that's in remission from recurring. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 5, 2017 Category: International Medicine & Public Health Source Type: news
Stephen King ’s September
Monarch of suspense Stephen King is abdicating, sort of. The blockbuster author wrote his latest novel, Sleeping Beauties, with his son Owen King, the author of 2013’s Double Feature. In the father and son’s first collaboration, all but one woman in the small town of Dooling fall prey to a mysterious sleeping sickness, leaving the men to fend for themselves in an increasingly violent world. Television rights to Sleeping Beauties were snapped up by Anonymous Content in the spring, months ahead of the novel’s Sept. 26 release.
Sleeping Beauties is just one of the elder King’s projects that fans can co...
Source: TIME.com: Top Science and Health Stories - September 14, 2017 Category: Consumer Health News Authors: Lucy Feldman Tags: Uncategorized Books horror Horror films Stephen King Source Type: news
Deadly parasite messaging tactic may help curb sleeping sickness
(University of Edinburgh) New insight into the parasites that cause sleeping sickness could offer a new pathway to tackling the disease, which poses a major threat to human health and causes severe livestock losses in parts of sub-Saharan Africa. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 4, 2017 Category: Infectious Diseases Source Type: news
New insights into the world of trypanosomes
(University of W ü rzburg) Such detailed images of the pathogen that causes sleeping sickness inside a host are unique so far: They illustrate the manifold ways in which the parasites move inside a tsetse fly. A research team from the University of W ü rzburg's Biocenter has presented the images. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 23, 2017 Category: Infectious Diseases Source Type: news
