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Stephen King ’s September
Monarch of suspense Stephen King is abdicating, sort of. The blockbuster author wrote his latest novel, Sleeping Beauties, with his son Owen King, the author of 2013’s Double Feature. In the father and son’s first collaboration, all but one woman in the small town of Dooling fall prey to a mysterious sleeping sickness, leaving the men to fend for themselves in an increasingly violent world. Television rights to Sleeping Beauties were snapped up by Anonymous Content in the spring, months ahead of the novel’s Sept. 26 release. Sleeping Beauties is just one of the elder King’s projects that fans can co...
Source: TIME.com: Top Science and Health Stories - September 14, 2017 Category: Consumer Health News Authors: Lucy Feldman Tags: Uncategorized Books horror Horror films Stephen King Source Type: news

Deadly parasite messaging tactic may help curb sleeping sickness
(University of Edinburgh) New insight into the parasites that cause sleeping sickness could offer a new pathway to tackling the disease, which poses a major threat to human health and causes severe livestock losses in parts of sub-Saharan Africa. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 4, 2017 Category: Infectious Diseases Source Type: news

New insights into the world of trypanosomes
(University of W ü rzburg) Such detailed images of the pathogen that causes sleeping sickness inside a host are unique so far: They illustrate the manifold ways in which the parasites move inside a tsetse fly. A research team from the University of W ü rzburg's Biocenter has presented the images. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 23, 2017 Category: Infectious Diseases Source Type: news

News from the pathogen that causes sleeping sickness
(University of W ü rzburg) A team of researchers from the University of W ü rzburg has discovered an interesting enzyme in the pathogens responsible for African sleeping sickness: It could be a promising target for drugs. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 22, 2017 Category: Infectious Diseases Source Type: news

Sleeping Sickness Medication May Help Lessen ASD Symptoms
Small study produced positive results with suramin, but more research needed (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - May 30, 2017 Category: Psychiatry Tags: Family Medicine, Neurology, Nursing, Pediatrics, Pharmacy, Psychiatry, Journal, Source Type: news

Could a Century-Old Drug Ease Autism Symptoms?
Small study produced positive results with the sleeping sickness medication suramin, but more research needed (Source: WebMD Health)
Source: WebMD Health - May 26, 2017 Category: Consumer Health News Source Type: news

Could a Century-Old Drug Help Ease Autism Symptoms?
FRIDAY, May 26, 2017 -- A drug first used in the early 1900s to treat sleeping sickness has shown promise in an early trial as a potential treatment for autism. The study involved just 10 boys, aged 5 to 14, with autism. This was the first human... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 26, 2017 Category: General Medicine Source Type: news

Researchers studying century-old drug in potential new approach to autism
(University of California - San Diego) In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 26, 2017 Category: International Medicine & Public Health Source Type: news

Merck partners with University of California, San Diego (UCSD) to fight Neglected Tropical Diseases
Merck, a leading science and technology company, today announced that it has agreed with the University of California, San Diego (UCSD) to share compounds under the WIPO Re:Search open innovation umbrella, thereby deepening its efforts in the fight against Neglected Tropical Diseases (NTDs) to identify potential cures for leishmaniasis, Chagas disease (American trypanosomiasis) and human African trypanosomiasis (HAT, sleeping sickness). (Source: World Pharma News)
Source: World Pharma News - April 20, 2017 Category: Pharmaceuticals Tags: Featured Merck Group Business and Industry Source Type: news

Tanzania: Fighting Neglected Diseases 'Means Uplifting Livelihoods'
[Citizen] Geneva -Here in Geneva, a child is depicted in a statue leading a blind man, who is affected by river blindness--one of Tanzania's five most common neglected tropical diseases (NTDs). Other NTDs being trachoma, lymphatic filariasis, sleeping sickness, soil-transmitted worms and leprosy. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 19, 2017 Category: African Health Source Type: news

Scientists use parasite's internal clock to attack sleeping sickness
(UT Southwestern Medical Center) The parasite that causes deadly sleeping sickness has its own biological clock that makes it more vulnerable to medications during the afternoon, according to international research that may help improve treatments for one of Africa's most lethal diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 23, 2017 Category: Global & Universal Source Type: news

Tick tock: Time to sleep? Sleeping parasite has own internal clock
(Instituto de Medicina Molecular) Researchers from iMM Lisboa have shown that the parasite responsible for sleeping sickness, Trypanosoma brucei, has its own internal clock, which allows it to anticipate daytime alterations of its surrounding environment and become more virulent. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 13, 2017 Category: Infectious Diseases Source Type: news

Scientists effectively disrupt communication between parasites that spread disease
A new intervention to tamper with parasites'communication system may lead to the development of drugs to treat, and prevent the spread of, devastating diseases such as African sleeping sickness, leishmaniasis and Chagas'disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 9, 2017 Category: Science Source Type: news

Kenya: Sleeping Sickness On the Rise, Warn Experts
[Nation] Kenya Tsetse and Trypanosomiasis Eradication Council (KENTTEC) has warned of rise in cases of sleeping sickness in the country. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 30, 2017 Category: African Health Source Type: news

This Man Went Abroad And Brought Back A Disease U.S. Doctors Had Never Seen
This article is part of HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to fight them. Lying in a hospital bed at the State Department medical unit in Washington, D.C., Claude Reece suspected he might have contracted malaria. It was 1995 and the American was sent back to the U.S. after coming down with a fever, sweats, pounding stomach aches and headaches, while on his first assignment working as a USAID country desk officer for Chad. “I felt that whatever ailment I contracted could be treated by the Medical Unit,” Reece told The Huffington Post ― that...
Source: Healthy Living - The Huffington Post - January 17, 2017 Category: Consumer Health News Source Type: news

This Man Went Abroad And Brought Back A Disease U.S. Doctors Had Never Seen
This article is part of HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to fight them. Lying in a hospital bed at the State Department medical unit in Washington, D.C., Claude Reece suspected he might have contracted malaria. It was 1995 and the American was sent back to the U.S. after coming down with a fever, sweats, pounding stomach aches and headaches, while on his first assignment working as a USAID country desk officer for Chad. “I felt that whatever ailment I contracted could be treated by the Medical Unit,” Reece told The Huffington Post ― that...
Source: Science - The Huffington Post - January 17, 2017 Category: Science Source Type: news

Medical screening and fly control could rapidly reduce sleeping sickness in key locations
In 2012, the World Health Organization set public health goals for reducing Gambian sleeping sickness, a parasitic infection. Now, by mathematically modeling the impact of different intervention strategies, researchers report have described how two-pronged approaches, integrating medical intervention and vector control, could substantially speed up the elimination of sleeping sickness in high burden areas of the Democratic Republic of Congo. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 5, 2017 Category: Science Source Type: news

Medical screening and fly control could rapidly reduce sleeping sickness in key locations
(PLOS) In 2012, the World Health Organization set public health goals for reducing Gambian sleeping sickness, a parasitic infection. Now, by mathematically modeling the impact of different intervention strategies, researchers reporting in PLOS Neglected Tropical Diseases have described how two-pronged approaches, integrating medical intervention and vector control, could substantially speed up the elimination of sleeping sickness in high burden areas of the Democratic Republic of Congo. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 5, 2017 Category: Infectious Diseases Source Type: news

Volunteers With No Medical Training Are Fighting Diseases The World Ignores
This article is part of HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to fight them. For people suffering from painful diseases in remote parts of the world, neighbors volunteering as health educators can be their best shot at getting help. Ordinary people, without any formal medical training, have stepped up to teach others about common illnesses in the province of Nampula, Mozambique, which has one of the highest rates of neglected tropical diseases in the country ― but where many people live in remote, rural communities, far from any health centers. As p...
Source: Healthy Living - The Huffington Post - January 3, 2017 Category: Consumer Health News Source Type: news

Volunteers With No Medical Training Are Fighting Diseases The World Ignores
This article is part of HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to fight them. For people suffering from painful diseases in remote parts of the world, neighbors volunteering as health educators can be their best shot at getting help. Ordinary people, without any formal medical training, have stepped up to teach others about common illnesses in the province of Nampula, Mozambique, which has one of the highest rates of neglected tropical diseases in the country ― but where many people live in remote, rural communities, far from any health centers. As p...
Source: Science - The Huffington Post - January 3, 2017 Category: Science Source Type: news

Deadly sleeping sickness set to be eliminated in six years
A Gambian sleeping sickness could be eliminated in 6 years thanks to new research. A combination of active screening and tsetse fly traps, it turns out, will be the key to quick elimination. Without changing current strategy, however, researchers warn that elimination isn't predicted until the next century. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 23, 2016 Category: Science Source Type: news

Deadly sleeping sickness set to be eliminated in 6 years
(University of Warwick) Gambian sleeping sickness -- a deadly parasitic disease spread by tsetse flies -- could be eliminated in six years in key regions in the Democratic Republic of Congo (DRC), according to new research by the University of Warwick. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 22, 2016 Category: Infectious Diseases Source Type: news

How Disease Detectives Unearthed A Forgotten Drug To Fight A Lethal Illness
This article is part HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to eliminate them. One morning a few years ago, a vial containing just a few drops of a long-forgotten drug candidate arrived at the office of bioengineer Els Torreele in Switzerland.  The compound, fexinidazole, had been studied at a drug company several decades earlier, but researchers had given up on it for no clear reason. Torreele had asked the company to unearth whatever it had left from its archive, hoping to get her hands on the final clue in a long process of painstaking detectiv...
Source: Healthy Living - The Huffington Post - December 13, 2016 Category: Consumer Health News Source Type: news

18 Diseases The World Has Turned Its Back On
This article is part HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to eliminate them. More than 1 billion people on the planet suffer from illnesses that the world pays little attention to. Neglected tropical diseases are a group of at least 18 diseases that primarily affect people living in poverty in tropical regions of the world and are virtually unknown elsewhere, according to the World Health Organization. These are diseases like river blindness, which has infected 18 million people worldwide and caused blindness in 270,000 people; or...
Source: Healthy Living - The Huffington Post - December 6, 2016 Category: Consumer Health News Source Type: news

18 Diseases The World Has Turned Its Back On
This article is part HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to eliminate them. More than 1 billion people on the planet suffer from illnesses that the world pays little attention to. Neglected tropical diseases are a group of at least 18 diseases that primarily affect people living in poverty in tropical regions of the world and are virtually unknown elsewhere, according to the World Health Organization. These are diseases like river blindness, which has infected 18 million people worldwide and caused blindness in 270,000 people; or...
Source: Science - The Huffington Post - December 6, 2016 Category: Science Source Type: news

This Group Helps Fight Devastating Diseases The World Ignores
This article is part HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to eliminate them. This group is developing drugs to treat diseases that are too often left behind. The Drugs For Neglected Diseases Initiative (DNDi) develops treatments for neglected tropical diseases ― a group of at least 18 diseases, such as elephantiasis and river blindness, which affect more than 1 billion people but are largely unknown and under-resourced since they mainly impact poor communities.  “They’re diseases that nobody has ever heard of, that are di...
Source: Science - The Huffington Post - December 1, 2016 Category: Science Source Type: news

This Doctor Gave Up His Shot At A Cushy Career To Cure A Little Known-Disease
This article is part HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to eliminate them. His name was Tendayi. He had watched five of his nine children die. Yet when he was diagnosed with a serious disease, he steadfastly held onto his will to live ― until he just couldn’t anymore.   Tendayi died about a decade ago, but his picture still sits on Dr. Wilfried Mutombo’s desk in Kinshasa, the capital of the Democratic Republic of Congo. It reminds him daily that a terrifying ― yet treatable ― disease is still killing far too many people. Muto...
Source: Healthy Living - The Huffington Post - November 29, 2016 Category: Consumer Health News Source Type: news

How You Can Help Stamp Out A Deadly Disease
This article is part HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to eliminate them. Some events have a way of getting under our skin. (The bitter 2016 election comes to mind.) They consume our thoughts and conversations, dominate our news and social feeds, maybe even keep us up at night. But some problems, for whatever reason, fail to capture the world’s attention. Take sleeping sickness, a parasitic disease caused by the bite of a fly, that has plagued Africa for centuries. Sleeping sickness is fatal if left untreated, and the most recent epidemic re...
Source: Healthy Living - The Huffington Post - November 22, 2016 Category: Consumer Health News Source Type: news

Solving the riddle of putrid camel urine could aid millions affected by sleeping sickness
Biochemists have solved an old mystery as to the cause of especially smelly camel urine, with implications for the millions of people affected by African parasites called trypanosomes. These parasites frequently cause fatalities via sleeping sickness. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 17, 2016 Category: Science Source Type: news

Solving the riddle of putrid camel pee could aid millions affected by sleeping sickness
(Trinity College Dublin) Trypanosome parasites that cause sleeping sickness break down amino acids to produce a metabolic by-product that suppresses the immune response. This by-product, which makes the urine of infected camels smell terrible, is a good candidate for anti-trypanosome drugs and therapies. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - November 17, 2016 Category: Global & Universal Source Type: news

New Clues to Sleeping Sickness
Disease-causing parasites found on skin of symptomless people Source: HealthDay Related MedlinePlus Pages: International Health, Parasitic Diseases (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 4, 2016 Category: Consumer Health News Source Type: news

New Clues to Sleeping Sickness
Title: New Clues to Sleeping SicknessCategory: Health NewsCreated: 10/3/2016 12:00:00 AMLast Editorial Review: 10/4/2016 12:00:00 AM (Source: MedicineNet Sleep General)
Source: MedicineNet Sleep General - October 4, 2016 Category: Sleep Medicine Source Type: news

New clues to sleeping sickness
HealthDay News Parasites that cause sleeping sickness can be found on the skin of people with no symptoms of the disease, a new study finds. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 4, 2016 Category: Consumer Health News Source Type: news

New Clues to Sleeping Sickness
MONDAY, Oct. 3, 2016 -- Parasites that cause sleeping sickness can be found on the skin of people with no symptoms of the disease, a new study finds. Sleeping sickness affects 4,000 to 8,000 people in sub-Saharan Africa each year. People are... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 3, 2016 Category: Journals (General) Source Type: news

Africa: New Finding Offers Breakthrough in Beating Sleeping Sickness
[The Conversation Africa] African sleeping sickness is a deadly disease spread by the bite of the tsetse fly, which only lives in sub-Saharan Africa. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 22, 2016 Category: African Health Source Type: news

New drug for tropical disease Trypanosomiasis discovered
Researchers are working to find the fastest way possible to treat and cure human African trypanosomiasis, long referred to as sleeping sickness. Human African trypanosomiasis, or HAT, is a tropical disease endemic to some rural communities in sub-Saharan Africa. A vector-borne parasitic disease, existing diagnosis and treatment regimens are complex, especially challenging in some of the world's most poverty-stricken regions. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 30, 2016 Category: Science Source Type: news

UGA researchers discover a drug for a tropical disease
(University of Georgia) Researchers at the University of Georgia are working to find the fastest way possible to treat and cure human African trypanosomiasis, long referred to as sleeping sickness. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 30, 2016 Category: Infectious Diseases Source Type: news

New research reveals single class of drug could treat three neglected diseases
New research conducted by scientists from the University of York and Novartis has revealed that one drug might be able to treat three fatal and usually neglected parasitic diseases, Chagas disease, leishmaniasis and human African trypanosomiasis, als … (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - August 9, 2016 Category: Pharmaceuticals Source Type: news

One drug is 'new hope' for three killer infections
A single drug can treat three deadly and neglected infections - Chagas disease, leishmaniasis and sleeping sickness - animal studies show.. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - August 9, 2016 Category: Consumer Health News Source Type: news

New compound offers hope for millions
A single class of drugs could treat chagas disease, leishmaniasis and sleeping sickness Related items fromOnMedica Parasitic worm increases women's fertility Weight loss linked to intestinal worms helps fight the parasite World ‘not prepared’ for Zika and Ebola Better use of vaccines could help tackle antimicrobial resistance Drugs firm waives drug patents in poor countries (Source: OnMedica Latest News)
Source: OnMedica Latest News - August 8, 2016 Category: UK Health Source Type: news

A single compound could treat Chagas disease, leishmaniasis and sleeping sickness
Scientists have identified a compound that can kill the parasites responsible for three neglected diseases: Chagas disease, leishmaniasis and sleeping sickness. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 8, 2016 Category: Science Source Type: news

Compound found to treat three parasitic tropical diseases
LONDON (Reuters) - Scientists have found a single class of drugs that can kill the parasites responsible for three tropical diseases that affect millions in Africa, Asia and Latin America - Chagas disease, leishmaniasis and sleeping sickness. (Source: Reuters: Health)
Source: Reuters: Health - August 8, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

A single compound could treat 3 parasitic diseases
(Wellcome Trust) Scientists have identified a compound that can kill the parasites responsible for three neglected diseases: Chagas disease, leishmaniasis and sleeping sickness. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 8, 2016 Category: Infectious Diseases Source Type: news

Fluorescent trypanosomes reveal invasion of skin and beyond following tsetse fly bites
( PLOS ) Trypanosome parasites cause sleeping sickness in Africa. If left untreated, the infection causes coma and eventually death. A study published on July 21 in PLOS Pathogens takes a close look at what happens after an infected tsetse fly transmits parasites into the skin of a mouse host and shows that very few parasites are needed to successfully colonize the host. In addition, multiplication of parasites at the bite site creates a reservoir from which parasites can be picked up by subsequent tsetse fly bites. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 21, 2016 Category: Infectious Diseases Source Type: news

New insect imaging technique may help victims of sleeping sickness
(Entomological Society of America) Researchers have employed near infrared still photographs and time-lapse video to observe the pupa of the living tsetse fly. The imaging technique may allow lab workers to identify male and female tsetse flies before they emerge as adults, which could make it easier to control them by using the Sterile Insect Technique. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 11, 2016 Category: Infectious Diseases Source Type: news

Malawi: Sleeping Sickness Diagnosis to be Simplified
[Nyasa Times] Professor John Chisi has said the country is moving towards the right direction in research for sleeping sickness which is a complex and big problem as it is difficult to diagnose. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 20, 2016 Category: African Health Source Type: news

Malawi: Research to Simplify Sleeping Sickness Diagnosis
[Malawi News Agency] Blantyre -Professor John Chisi has said the country is moving towards the right direction in research for sleeping sickness which is a complex and big problem as it is difficult to diagnose. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 19, 2016 Category: African Health Source Type: news

Discovery of enzyme in the sleeping sickness parasite streamlines drug development
The single-celled parasite causing African sleeping sickness has a defense mechanism against potential pharmaceuticals under development against the disease, new research indicates. The deadly parasite has an enzyme that can cleave and hence disarm adenosine analogue pharmaceuticals. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 18, 2016 Category: Science Source Type: news

Discovery of enzyme in the sleeping sickness parasite streamlines drug development
(Umea University) Researchers from Umeå University in Sweden have discovered that the single-celled parasite causing African sleeping sickness has a defense mechanism against potential pharmaceuticals under development against the disease. The deadly parasite has an enzyme that can cleave and hence disarm adenosine analogue pharmaceuticals. This according to a study recently published in the Journal of Biological Chemistry. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 18, 2016 Category: Global & Universal Source Type: news

Nitric oxide protects against parasite invasion and brain inflammation by keeping the blood brain barrier intact
(PLOS) African trypanosomiasis is called 'sleeping sickness' because when the infection is untreated, trypanosome parasites will invade the brain and cause disruption of sleeping patterns and irreversible neurological damage. A study published on Feb. 25 in PLOS Pathogens reports that in a mouse model of trypanosome disease, nitric oxide plays an unexpected role in preserving the integrity of the blood brain barrier, thereby reducing parasite invasion into the brain, and likely limiting neurological damage. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 25, 2016 Category: Infectious Diseases Source Type: news