[Press Release] Deadly Gaps Persist in New Drug Development for Neglected Diseases
This study reports a slight increase of 2.4 new products/year for 2000-2011 and predicts 4.7 new products/year through 2018.
"Although strides have been made in the last decade, we still see deadly gaps in new medicines for some of the world's least visible patients," said Dr. Nathalie Strub-Wourgaft, medical director of DNDi. "We need to get more treatment candidates, NCEs or existing ones for repurposing, into and through the R&D pipeline to fundamentally change the way we manage these diseases."
"Our patients are still waiting for true medical breakthroughs," said D...
Source: MSF News - December 3, 2013 Category: Global & Universal Source Type: news
Breaking new ground for drug discovery research in the fight against sleeping sickness
Scientists at the University of Oulu, Finland, and at the Helmholtz Center Berlin (HZB) have shown the way to new directions in drug development against African sleeping sickness and other tropical parasitic infections. This was based on the structural analysis of the enzyme thiolase, which plays a central role in lipid metabolism in the parasite that causes sleeping sickness. The researchers examined the biomolecule's structure at the MX beamline of electron storage ring, BESSY II, at the HZB... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 11, 2013 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
Blocking the active site of thiolase
(Helmholtz-Zentrum Berlin für Materialien und Energie) Scientists at the University of Oulu, Finland, and at the HZB break new ground for drug discovery research in the fight against sleeping sicknessScientists at the University of Oulu, Finland, and at the Helmholtz Center Berlin have shown the way to new directions in drug development against African sleeping sickness and other tropical parasitic infections. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 7, 2013 Category: Global & Universal Source Type: news
Uganda: Worrying Sleeping Sickness Merger
[New Vision]Health experts are worried about the narrowing gap between two types of sleeping sickness from the eastern region of the country to the northern. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 1, 2013 Category: African Health Source Type: news
Deadly Gaps Persist in New Drug Development for Neglected Diseases
This study reports a slight increase of 2.4 new products/year for 2000-2011 and predicts 4.7 new products/year through 2018.
"Although strides have been made in the last decade, we still see deadly gaps in new medicines for some of the world's least visible patients," said Dr. Nathalie Strub-Wourgaft, medical director of DNDi. "We need to get more treatment candidates, NCEs or existing ones for repurposing, into and through the R&D pipeline to fundamentally change the way we manage these diseases."
"Our patients are still waiting for true medical breakthroughs," said D...
Source: MSF News - October 24, 2013 Category: Global & Universal Source Type: news
Clemson hosting scientists who study devastating diseases
(Clemson University) Clemson University is hosting the region's leading scientists for discussions about the causative agents of some of the most devastating and intractable diseases of humans, including malaria, amoebic dysentery, sleeping sickness, Chagas disease and fungal meningitis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 24, 2013 Category: Global & Universal Source Type: news
An end to the deadly disease of sleeping sickness?
A tag team of two bacteria, one of them genetically modified, has a good chance to reduce or even eliminate the deadly disease African trypanosomiasis, or sleeping sickness, researchers at Oregon State University conclude in a recent mathematical modeling study. African trypanosomiasis, caused by a parasite carried by the tsetse fly, infects 30,000 people in sub-Saharan Africa each year and is almost always fatal without treatment. In a 2008 epidemic, 48,000 people died... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 7, 2013 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
In a single-cell organism a 'mistake' is actually a rewrite essential to life
A tiny but unexpected change to a segment of RNA in a single-cell organism looks a lot like a mistake, but is instead a change to the genetic information that is essential to the organism's survival. Scientists have discovered this RNA "edit" in Trypanosoma brucei, a parasite that causes sleeping sickness in Africa and Chagas disease in Latin America. Though the organism is a model system for this work, the finding could lead to a new drug target to fight the parasite if higher species don't share this genetic behavior. Some of the organism's genetic activity was already known... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 7, 2013 Category: Consumer Health News Tags: Genetics Source Type: news
Innovative approach could ultimately end deadly disease of sleeping sickness
(Oregon State University) A tag team of two bacteria, one of them genetically modified, has a good chance to reduce or even eliminate the deadly disease African trypanosomiasis, or sleeping sickness, researchers at Oregon State University conclude in a recent mathematical modeling study. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 3, 2013 Category: Global & Universal Source Type: news
Africa: GM Bacteria 'Could Eliminate' Sleeping Sickness
[SciDev.Net]Releasing tsetse flies that carry genetically modified bacteria resistant to the parasite that causes sleeping sickness could eliminate the disease in Africa under certain conditions, a modelling study has shown. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 26, 2013 Category: African Health Source Type: news
Uganda: New Tools to Fight Sleeping Sickness
[New Vision]Mark Biong Deng, a student from South Sudan studying in Kampala, suffered from what was for long thought to be malaria. But strangely, all tests for malaria turned out negative and it took experts time to discover it was another problem. It was sleeping sickness. (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - September 23, 2013 Category: Infectious Diseases Source Type: news
Sleeping Sickness in the DRC
When I first met up with the team in the Central African Republic, it was the first time I had left my home country. Before long however, I was moving on to South Sudan with the team to start up the project there. My first time in an English speaking country... (Source: MSF News)
Source: MSF News - August 28, 2013 Category: Global & Universal Authors: Dr Papy Banza Source Type: news
DRC: MSF screens 16,000 people for sleeping sickness
MSF has just completed a five-month project to combat sleeping sickness in the Democratic Republic of Congo, during which more than 16,000 people were screened for the disease. (Source: MSF News)
Source: MSF News - August 28, 2013 Category: Global & Universal Authors: Nick Source Type: news
Congo-Kinshasa: MSF Completes Sleeping Sickness Screening for 16,000 People
[MSF]The international medical humanitarian organisation Médecins Sans Frontières (MSF) has just completed a five month project to combat sleeping sickness in the Democratic Republic of Congo, during which more than 16,000 people were screened for the disease. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 28, 2013 Category: African Health Source Type: news
Scientists make breakthrough in finding cure for sleeping sickness
Scientists in Belgium say they have made significant progress in creating a cure for the most common form of sleeping sickness. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - August 21, 2013 Category: Pharmaceuticals Source Type: news
