Fight Aging! Newsletter, November 19th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
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Source: Fight Aging! - November 18, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Choroidal Melanoma :DAMS Unplugged
Presenting an integrated case discussion on choroidal melanoma in DAMS unplugged series.Famous Radiology Blog http://www.sumerdoc.blogspot.com
TeleRad Providers at www.teleradproviders.com Mail us at sales@teleradproviders.com (Source: Sumer's Radiology Site)
Source: Sumer's Radiology Site - November 15, 2018 Category: Radiology Authors: Sumer Sethi Source Type: blogs
A Popular Science View of Checkpoint Inhibitor Cancer Immunotherapies
Checkpoint inhibitor therapies are a demonstrably successful approach to cancer immunotherapy. They suppress a mechanism that normally restrains immune cells from attacking other cells. This mechanism is abused by cancers, alongside a variety of other ways in which the immune system can be subverted or quieted. Any advanced tumor tends to have evolved into a state in which it is ignored or even helped by the immune system. Checkpoint inhibitor therapies are an improvement on chemotherapy when it comes to the trade-off between harming the cancer and harming the patient, as well as in the odds of success, but still present r...
Source: Fight Aging! - November 13, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, November 12th 2018
This study's researchers approached all people turning 85 in 2006 in two cities in the UK for participation. At the beginning of the study in 2006-2007, there were 722 participants, 60 percent of whom were women. The participants provided researchers with information about what they ate every day, their body weight and height measurements, their overall health assessment (including any level of disability), and their medical records.
The researchers learned that more than one-quarter (28 percent) of very old adults had protein intakes below the recommended dietary allowance. The researchers noted that older adults w...
Source: Fight Aging! - November 11, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Last Month in Oncology with Dr. Bishal Gyawali
By BISHAL GYAWALI MD
Me-too deja vu
I read the report of a phase 3 RCT of a “new” breast cancer drug but I had the feeling that I had already read this before. Later I realized that this was indeed a new trial of a new drug, but that I had read a very similar report of a very similar drug with very similar results and conclusions. This new drug is a PARP inhibitor called talazoparib and the deja vu was related to another PARP inhibitor drug called olaparib tested in the same patient population of advanced breast cancer patients with a BRCA mutation. The control arms were the same: physician choice of drug, except t...
Source: The Health Care Blog - November 8, 2018 Category: Consumer Health News Authors: matthew holt Tags: Drug Discovery Pharmaceuticals Bishal Gyawali Cancer immunotherapy Oncology Source Type: blogs
Greater Cancer Risk for Taller People is Near Entirely Due to Having More Cells
There has been some debate in the research community as to whether the observed relationship between cancer risk and height in our species is due to (a) taller people having more cells, and thus more chances to suffer a cancerous mutation, or (b) some more indirect factor, such as, for example, the role of growth hormone in cellular metabolism. The author of this study marshals data to argue convincingly for the former hypothesis, for most forms of cancer.
The multistage model of carcinogenesis predicts cancer risk will increase with tissue size, since more cells provide more targets for oncogenic somatic mutation...
Source: Fight Aging! - November 5, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Best Post of October 2018: Young adult with an iridic mass extending into the ciliary body
The next in our " Best of the Month " series comes from October 9, 2018:Melanoma markers were negative. Smooth muscle markers were positive. This case was determined to be an epithelioid leiomyoma. I didn ' t do electron microscopy to look for mitochondia, but it may well be what Ursula Schlotzer-Schredhardt et al. have called a mitochondria-rich epithelioid leiomyoma (Arch Ophthalmol, Vol 120, January 2002). (Source: neuropathology blog)
Source: neuropathology blog - November 1, 2018 Category: Radiology Tags: Best of the Month series eye ophthalmic pathology Source Type: blogs
Microfluidic Chips to Diagnose and Characterize Cancer: Interview with Prof. Fatih Sarioglu, Georgia Tech
Research into microfluidic devices to aid in cancer diagnosis promises huge leaps in making diagnostics easier and faster. Much of this research is focused on chips that can trap circulating tumor cells (CTCs) which are present in blood samples. CTCs are released from a primary tumor and can form metastases in other sites in the body, a process which is responsible for more than 90% of cancer-related deaths.
Being able to easily detect and assess CTCs in the blood would provide clinicians with the ability to minimally-invasively diagnose cancer and provide researchers with a window on cancer metastasis and progression. At ...
Source: Medgadget - October 24, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Exclusive Oncology Source Type: blogs
Dr. Holly Christman moves practice to Marin
After many years working in downtown San Francisco, dermatologist Holly Christman has left that group for a prestigious practice in Marin. We wish Holly the best--Marin is lucky to have her!For those seeking care in San Francisco, Union Square Dermatology is located in the venerable 450 Sutter Street Building. The four Board Certified dermatologists provide services such as mole and skin cancer checks, Mohs surgery, management of rosacea, eczema and psoriasis. The practice is in network with Aetna, Cigna and United Health Care PPO plans and Medicare. Cosmetic options included Botox, fillers, lasers for sun sp...
Source: Skinema, dermatology in the media blog - October 20, 2018 Category: Dermatology Authors: vail reese Tags: Health Source Type: blogs
Dark patches on the face may be melasma
You may have heard melasma referred to as “the mask of pregnancy,” because it is sometimes triggered by an increase in hormones in pregnant women. But while the condition may be common among pregnant women, you don’t have to be pregnant to experience melasma.
“It’s not only associated with pregnancy, but can affect women at all stages of life,” says Dr. Shadi Kourosh, director of the Pigmentary Disorder and Multi-Ethnic Skin Clinic at Harvard-affiliated Massachusetts General Hospital. And it may last for many years. “Women who develop melasma in their teens or 20s or 30s may see it stay around...
Source: Harvard Health Blog - October 19, 2018 Category: Consumer Health News Authors: Kelly Bilodeau Tags: Health Pregnancy Skin and Hair Care Source Type: blogs
Young adult with an iridic mass extending into the ciliary body
Melanoma markers were negative. Smooth muscle markers were positive. This case was determined to be anepithelioid leiomyoma. I didn ' t do electron microscopy to look for mitochondia, but it may well be whatUrsula Schlotzer-Schredhardtet al. have called amitochondria-rich epithelioid leiomyoma(Arch Ophthalmol, Vol 120, January 2002). (Source: neuropathology blog)
Source: neuropathology blog - October 9, 2018 Category: Radiology Tags: eye ophthalmic pathology Source Type: blogs
Fight Aging! Newsletter, October 8th 2018
This article, unfortunately paywalled, is interesting to note as a mark of the now increasingly energetic expansion of commercial efforts in longevity science. David Sinclair has been building a private equity company to work in many areas relevant to this present generation of commercial longevity science; while I'm not sold on his primary research interests as the basis for meaningful treatments for aging, he is diversifying considerably here, including into senolytics, the clearance of senescent cells demonstrated to produce rejuvenation in animal studies. This sort of approach to business mixes aspects of investing and...
Source: Fight Aging! - October 7, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Mesoectodermal Leiomyoma of the Ciliary Body
A 47-year-old woman is suspected of having a ciliary body melanoma (A). Histologic sections (B and C) show large ciliary body tumor composed of tumor cells in a fibrillar cytoplasmic matrix. Electron microscopy (D) shows a dense osmophiliic structure known as askeinoid fiber.Immunohistochemistry helped to confirm that this was a leiomyoma.(Case reported by J. Campbell et al. Ultrastruct Pathol 28:559, 1997.) (Source: neuropathology blog)
Source: neuropathology blog - October 5, 2018 Category: Radiology Tags: eye Source Type: blogs
September is Blood Cancer Awareness Month
When, many many years ago (19, but who’s counting? ), my doctor uttered those two words, “mieloma multiplo,” I thought he’d said: “melanoma.”
Who’d ever heard of multiple myeloma???
Ahhhh, how things change!!!
And today, thanks to my research, mixed in with quite a bit of determination (stubbornness?), and, oh yes, quite a bit of luck, I’m doing okay:
No CRAB symptoms.
No conventional treatments.
Just…curcumin (mainly).
And, for sure!, lots of awareness!!! (Source: Margaret's Corner)
Source: Margaret's Corner - September 24, 2018 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll mieloma multiplo; myeloma multiple myeloma Source Type: blogs
