CCR Grand Rounds: Melanoma Control by its Cross Talk with the Microenvironment
CCR Grand Rounds “ Melanoma Control by its Cross Talk with the Microenvironment ” Ze'ev Ronai, Ph.D.Jeanne and Gary Herberger Leadership Chair in Cancer ResearchProfessor, Tumor Initiation and Maintenance ProgramSanford Burnham Prebys Medical Discovery InstituteDirector, NCI-Designated Cancer CenterFriday, October 27, 202312:00 – 1:00 p.m.Lipsett AmphitheaterAir date: 10/27/2023 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - October 13, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

CCR Grand Rounds - Personalized Cellular Therapy for Cancer
CCR Grand Rounds Antoni Ribas, M.D., Ph.D. is Professor of Medicine, Professor of Surgery, and Professor of Molecular and Medical Pharmacology at the University of California Los Angeles (UCLA), Director of the Tumor Immunology Program at the Jonsson Comprehensive Cancer Center (JCCC), Director of the Parker Inst itute for Cancer Immunotherapy (PICI) Center at UCLA. Dr Ribas is a physician-scientist who conducts laboratory and clinical research in malignant melanoma, focusing on gene engineered T cells, PD-1 blockade and BRAF targeted therapies. His National Cancer Institute (NCI), State of California and fo undation-sup...
Source: Videocast - All Events - February 2, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

CCR Grand Rounds
“ Personalized Celular Therapy for Cancer ” Antoni Ribas, M.D., Ph.D. PROFESSOR OF MEDICINE WITH TENURE PROFESSOR OF SURGERY PROFESSOR OF MOLECULAR AND MEDICAL PHARMACOLOGY UNIVERSITY OF CALIFORNIA LOS ANGELES (UCLA) Friday, February 3, 2023 12:00 – 1:00 p.m. Lipsett Amphitheater (Masks required) Also available to view via NIH Videocast. Antoni Ribas, M.D., Ph.D. is Professor of Medicine, Professor of Surgery, and Professor of Molecular and Medical Pharmacology at the University of California Los Angeles (UCLA), Director of the Tumor Immunology Program at the Jonsson Com prehensive Cancer Center (JCCC), D...
Source: Videocast - All Events - January 24, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

The Case for BK Polyomavirus as a Cause of Bladder Cancer
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Buck ’ s lab studies polyomaviruses. A great majority of healthy adults chronically shed polyomavirus virions in their urine and from the surface of their skin. Although these lifelong infections generally aren't known to cause symptoms in healthy individuals, under conditions of immune impairment polyomaviruses can cause disease. For example, BK polyomavirus (BKV) causes kidney and bladder damage in organ transplant patients, while its close relative JCV causes a lethal brain disease in patients on immunosuppressive therapies and in individuals suffering from ...
Source: Videocast - All Events - March 2, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

4 Awesome Discoveries You Probably Didn  ’ t Hear About This Week  — Episode 34
Ancient shark in 3-D, Scary robofish, skin cancer answer, and crops in deep water 3-D reconstructions ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - September 28, 2019 Category: Science Source Type: video

Rational Combinatorial Approaches to Immune Checkpoint Blockade
CCR Grand Rounds F. Stephen Hodi, M.D., is the Director of the Melanoma Center and the Center for Immuno-Oncology at Dana-Farber/Brigham and Women's Cancer Center and Professor of Medicine at Harvard Medical School. He received his MD degree from Cornell University Medical College in 1992. Dr. Hodi completed his postdoctoral training in Internal Medicine at the Hospital of the University of Pennsylvania and Medical Oncology training at Dana-Farber cancer Institute where he joined the faculty in 1995. His research focuses on gene therapy, the development of immune therapies, and first-in-human studies for malignant melanoma...
Source: Videocast - All Events - February 20, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Senescence: live fast, die young, and leave a good-looking corpse
NIH Director's Wednesday Afternoon Lecture Series In addition to serving as director of NCI, Dr. Sharpless continues his research in understanding the biology of the aging process that promotes the conversion of normal self-renewing cells into dysfunctional cancer cells. Dr. Sharpless has made seminal contributions to the understanding of the relationship between aging and cancer, and in the preclinical development of novel therapeutics for melanoma, lung cancer, and breast cancer.For more information go tohttps://oir.nih.gov/walsAir date: 11/28/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - October 9, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

NCI Support for Cancer Immunology
Immunonology IG Seminar Norman E. “ Ned ” Sharpless, M.D., was officially sworn in as the 15th director of the National Cancer Institute (NCI) on October 17, 2017. Prior to his appointment, Dr. Sharpless served as the director of the University of North Carolina (UNC) Lineberger Comprehensive Cancer Center, a position he held since January 2014. Dr. Sharpless was a Morehead Scholar at UNC – Chapel Hill and received his undergraduate degree in mathematics. He went on to pursue his medical degree from the UNC School of Medicine, graduating with honors and distinction in 1993. He then completed his internal medicine res...
Source: Videocast - All Events - June 12, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Skin resident T cells in human health and disease
Immunology IG Seminar Dr. Clark attended Caltech as an undergraduate, where she was told to avoid a career in medicine. Despite this excellent advice, she completed the M.D./Ph.D. program at Harvard Medical School and now serves as the Shing-Yiu Yip and Cecilia M. Hepp Associate Professor of Dermatology at Harvard Medical School and the Director of the NIAMS P30 funded Human Skin Disease Resource Center. Her research focuses on the study of human T cell responses in skin and other peripheral tissues, including T cell function in healthy skin, impaired T cell migration and responses in skin cancer, and maladaptive T cell ac...
Source: Videocast - All Events - April 4, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Immunonology IG Seminar: “ Skin resident T cells in human health and disease ”
Dr. Clark attended Caltech as an undergraduate, where she was told to avoid a career in medicine. Despite this excellent advice, she completed the M.D./Ph.D. program at Harvard Medical School and now serves as the Shing-Yiu Yip and Cecilia M. Hepp Associate Professor of Dermatology at Harvard Medical School and the Director of the NIAMS P30 funded Human Skin Disease Resource Center. Her research focuses on the study of human T cell responses in skin and other peripheral tissues, including T cell function in healthy skin, impaired T cell migration and responses in skin cancer, and maladaptive T cell activation in inflammato...
Source: Videocast - All Events - April 3, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Loss of Type I Interferon Negative Regulation – Lessons from Human Genetics
Immunonology IG Seminar Dr. Dusan Bogunovic is an Assistant Professor in the Department of Microbiology, Department of Pediatrics at Mindich Child Health and Development Institute at the Icahn School of Medicine at Mount Sinai in New York. He obtained his PhD in Immunology at NYU Medical School where he studied innate immune signaling in dendritic cells as a function of their ability to mount an adaptive immune response against melanoma. That work has inspired two clinical trials. He did his postdoctoral fellowship at The Rockefeller University with Jean-Laurent Casanova where he studied how host genetics contribute to inf...
Source: Videocast - All Events - November 2, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Developing Therapies for Ras-Driven Tumors
NCI's Center for Cancer Research (CCR) Grand Rounds Dr. Cichowski ’ s research goals are to elucidate mechanisms that drive human cancer, identify novel therapeutic targets, and generate robust animal models to facilitate these efforts. A related goal is to establish collaborative relationships with clinicians to translate basic scientific findings into clinical trials. Her principal scientific interest is to understand how the Ras pathway, which is deregulated in the majority of human cancers, promotes tumorigenesis. She and her colleagues have been investigating this question in nervous system tumors, prostate, lung, m...
Source: Videocast - All Events - October 16, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

The Hedgehog Pathway and the Race against Tumor Resistance
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Oro is a Professor of Dermatology, Associate Director of the Center for Definitive and Curative Medicine, a member of the Institute for Stem Cell Biology and Regenerative Medicine and the Stanford Cancer Institute at Stanford University, and the Cancer Biology and Stem Cell graduate student programs. He trained in the medical scientist program at the Salk Institute under Ron Evans lab, working on functions of novel orphan nuclear receptors in model systems. During Dermatology residency/fellowship in Matthew Scott ’ s lab at Stanford, he helped solidify the link ...
Source: Videocast - All Events - May 1, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

Is the Right Flavor of Inflammation the Key to Successful Cancer Therapy?
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Romina Goldszmid received her Ph.D. working on dendritic cell-based vaccines for melanoma immunotherapy from the University of Buenos Aires, Argentina, part of which was performed as a visiting scholar in the laboratory of Dr. Ralph Steinman at the Rockefeller University. She then did her postdoctoral training in infectious diseases immunology with Dr. Alan Sher in the Laboratory of Parasitic Diseases (LPD) at NIAID. There, Dr. Goldszmid focused on the interplay between dendritic cells and natural killer cells during the early response to Toxoplasma gondii infecti...
Source: Videocast - All Events - January 23, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

Merkel Cells and Merkel Cell Carcinoma
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Brownell is a Board Certified Dermatologist and a Fellow of the American Academy of Dermatology. He obtained degrees in electrical engineering and mathematics prior to undergoing MD/PhD training at Baylor College of Medicine. Dr. Brownell completed a dermatology residency at the New York University School of Medicine, and a postdoctoral research fellowship in the laboratory of Dr. Alexandra Joyner at the Sloan-Kettering Institute. On the clinical faculty at the Memorial Sloan-Kettering Cancer Center, his practice focused on patients with high-risk skin cancers. In...
Source: Videocast - All Events - September 20, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video