Pelvic Floor Dysfunction in Transgender Men on Gender-affirming Hormone Therapy: A Descriptive Cross-sectional Study
ConclusionsTransgender men on hormone therapy have a high incidence of PFD (94.1%) and experience a greater occurrence of urinary symptoms (86.7%). (Source: International Urogynecology Journal and Pelvic Floor Dysfunction)
Source: International Urogynecology Journal and Pelvic Floor Dysfunction - April 25, 2024 Category: OBGYN Source Type: research
MicroRNA-503-5p protects streptozotocin-induced erectile dysfunction in diabetic rats by downregulating SYDE2
This study aimed to figure out microRNA (miR)-503-5p/SYDE2 axis' latent mechanisms in streptozotocin-induced diabetic rat sexual dysfunction. A model of erectile dysfunction (ED) in diabetic rats was established by injecting streptozotocin. MiR-503-5p and SYDE2 in ED rats were altered by injection of miR-503-5p mimic or si/oe-SYDE2. The targeting link between miR-503-5p and SYDE2 was testified. ICP/MAP value was tested by pressure sensor; Penile capillary abundance was assessed; Penile cGMP and AGEs were detected; penile smooth muscle cell apoptosis was assessed; MiR-503-5p and SYDE2 were tested. In streptozotocin-induced ...
Source: Cellular and Molecular Biology - April 23, 2024 Category: Molecular Biology Authors: Gangqin Li Lin Jiang Kuan Bai Guangxing Tan Source Type: research
MicroRNA-503-5p protects streptozotocin-induced erectile dysfunction in diabetic rats by downregulating SYDE2
This study aimed to figure out microRNA (miR)-503-5p/SYDE2 axis' latent mechanisms in streptozotocin-induced diabetic rat sexual dysfunction. A model of erectile dysfunction (ED) in diabetic rats was established by injecting streptozotocin. MiR-503-5p and SYDE2 in ED rats were altered by injection of miR-503-5p mimic or si/oe-SYDE2. The targeting link between miR-503-5p and SYDE2 was testified. ICP/MAP value was tested by pressure sensor; Penile capillary abundance was assessed; Penile cGMP and AGEs were detected; penile smooth muscle cell apoptosis was assessed; MiR-503-5p and SYDE2 were tested. In streptozotocin-induced ...
Source: Mol Biol Cell - April 23, 2024 Category: Molecular Biology Authors: Gangqin Li Lin Jiang Kuan Bai Guangxing Tan Source Type: research
MicroRNA-503-5p protects streptozotocin-induced erectile dysfunction in diabetic rats by downregulating SYDE2
This study aimed to figure out microRNA (miR)-503-5p/SYDE2 axis' latent mechanisms in streptozotocin-induced diabetic rat sexual dysfunction. A model of erectile dysfunction (ED) in diabetic rats was established by injecting streptozotocin. MiR-503-5p and SYDE2 in ED rats were altered by injection of miR-503-5p mimic or si/oe-SYDE2. The targeting link between miR-503-5p and SYDE2 was testified. ICP/MAP value was tested by pressure sensor; Penile capillary abundance was assessed; Penile cGMP and AGEs were detected; penile smooth muscle cell apoptosis was assessed; MiR-503-5p and SYDE2 were tested. In streptozotocin-induced ...
Source: Cellular and Molecular Biology - April 23, 2024 Category: Molecular Biology Authors: Gangqin Li Lin Jiang Kuan Bai Guangxing Tan Source Type: research
Sexual dysfunction in patients with cancer, a challenge in oncology practice: results of the CLARIFY project
ConclusionsOur population has a high prevalence of SD, which supports the need to increase awareness of this disorder among the medical oncology team and the importance of including sexual health assessment in oncological patient follow-up. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - April 22, 2024 Category: Cancer & Oncology Source Type: research
Invasive neurostimulation in neuro-urology: state of the art
Aktuelle Urol. 2024 Apr 17. doi: 10.1055/a-2261-4792. Online ahead of print.ABSTRACTModulation or stimulation of the nerves supplying the lower urinary tract is a possible treatment option for dysfunction of the lower urinary tract, pelvic floor and rectum if conservative or minimally invasive treatment approaches fail. This overview shows the possibilities and limitations of sacral neuromodulation, sacral deafferentation with sacral anterior root stimulation and conus deafferentation.Sacral neuromodulation (SNM) is a procedure for the treatment of refractory pelvic floor dysfunction of various origins (idiopathic, neuroge...
Source: Aktuelle Urologie - April 17, 2024 Category: Urology & Nephrology Authors: Ines Kurze Ralf B öthig Arndt van Ophoven Source Type: research
Invasive neurostimulation in neuro-urology: state of the art
Aktuelle Urol. 2024 Apr 17. doi: 10.1055/a-2261-4792. Online ahead of print.ABSTRACTModulation or stimulation of the nerves supplying the lower urinary tract is a possible treatment option for dysfunction of the lower urinary tract, pelvic floor and rectum if conservative or minimally invasive treatment approaches fail. This overview shows the possibilities and limitations of sacral neuromodulation, sacral deafferentation with sacral anterior root stimulation and conus deafferentation.Sacral neuromodulation (SNM) is a procedure for the treatment of refractory pelvic floor dysfunction of various origins (idiopathic, neuroge...
Source: Aktuelle Urologie - April 17, 2024 Category: Urology & Nephrology Authors: Ines Kurze Ralf B öthig Arndt van Ophoven Source Type: research
Efficacy of a web-based psychoeducational intervention, Fex-can sex, for young adult childhood cancer survivors with sexual dysfunction: A randomized controlled trial
CONCLUSION: The Fex-Can Sex intervention shows potential to improve sexual function, especially among those with greater dysfunction. To increase adherence and effect, we recommend the intervention to be further developed including more tailored content.CLINICAL TRIAL REGISTRATION: ISRCTN Registry, trial number: 33081791 (registered on November 27, 2019).PMID:38623084 | PMC:PMC11016752 | DOI:10.1016/j.invent.2024.100739 (Source: Cancer Control)
Source: Cancer Control - April 16, 2024 Category: Cancer & Oncology Authors: Kristina Fagerkvist Kirsi Jahnukainen Lisa Ljungman Claudia Lampic Lena Wettergren Source Type: research
Validation of Qualisex questionnaire to evaluate sexual dysfunction in women affected by fibromyalgia
CONCLUSIONS: This study validated Qualisex questionnaire as a good test for the sexual disorders' evaluation in FM women. Its use allows the assessment of different factors associated with sexual dysfunction, showing an impact of FM on sexuality. Moreover, due to demotivation feelings, sexual dysfunction contributes to worsen patients' quality of life.PMID:38607686 | DOI:10.55563/clinexprheumatol/a00yur (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 12, 2024 Category: Rheumatology Authors: Chiara Gioia Giulio Dolcini Cristina Iannuccelli Martina Favretti Daniele Franculli Piercarlo Sarzi-Puttini Fabrizio Conti Roberta Priori Manuela Di Franco Source Type: research
Attitudes and practice patterns of Finnish obstetrician-gynecologists regarding patients' sexual problems
Sexuality is an important aspect of quality of life [1,2]. However, sexual problems are common, with the prevalence of female sexual dysfunction (FSD) ranging from 40 % to 50 %, irrespective of age [3]. Many different health care professionals—for instance, certified nurses, sexuality educators, sexuality counselors, and sexuality therapists, as well as physicians in various fields—take part in the management of sexual problems. Obstetrician-gynecologist s (OB/GYNs) are some of the key health care professionals who diagnose and treat female sexual problems, but previous studies have reported that OB/GYNs underesti...
Source: Maturitas - April 12, 2024 Category: Primary Care Authors: Anna Aromaa, P äivi Polo-Kantola, Sanna-Mari Manninen, Jarna Grönlund, Markus Riskumäki, Tero Vahlberg, Katja Kero Tags: Original article Source Type: research
Minor impact of anastomotic leakage in anterior resection for rectal cancer on long-term male urinary and sexual function
ConclusionAnastomotic leakage after anterior resection had a minor negative impact on urinary and sexual function in men. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - April 9, 2024 Category: Gastroenterology Source Type: research
