Why is Sepsis a Condition of the Elderly?
Sepsis and consequent septic shock occur more frequently in the old and cause greater harm and mortality in older individuals. The condition occurs when an infection spurs the immune system into a state of runaway inflammation and then shutdown, sufficient to disrupt or permanently damage metabolism and organ function. The open access paper here dives into the details of age-related immune system dysfunction, with an eye to explaining why exactly these failures cause sepsis to be both worse and more prevalent in the elderly. As for so many of the specific frailties of old age, the best solution is to repair the immune syst...
Source: Fight Aging! - November 13, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
LITFL Review 300
LITFL • Life in the Fast Lane Medical Blog
LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Welcome to the 300th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM.
The Most Fair Dinkum Ripper Beauts of the Week
Flavia Machado is this week’s Master of Intensive care, discussing how she manages things i...
Source: Life in the Fast Lane - October 1, 2017 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs
The Subtle Signs of Sepsis Infographic
Sepsis has been a major challenge in healthcare for a long time. This was highlighted really well on the Wolters Kluwer Nursing Center website:
Throughout my experience in health care over the past 30 plus years, the diagnosis of sepsis has been one of the most challenging. Sepsis affects millions of people worldwide and one in four of the people affected will die. The way we recognize and treat sepsis has changed over the years, and in January 2017, the International Guidelines for Management of Sepsis and Septic Shock: 2016 was published. This update to the 2012 guidelines, emphasizes that patients with sepsis should be ...
Source: EMR and HIPAA - September 27, 2017 Category: Information Technology Authors: John Lynn Tags: Clinical Decision Support Healthcare Healthcare Communication Healthcare Interoperability HealthCare IT Sepsis Sepsis Identification Vocera Vocera Badge Wolters Kluwer Source Type: blogs
Quicker Sepsis Treatment Saves Lives: Q & A With Sepsis Researcher Christopher Seymour
Sepsis is a serious medical condition caused by an overwhelming immune response to infection. The body’s infection-fighting chemicals trigger widespread inflammation, which can lead to blood clots and leaky blood vessels. As a result, blood flow is impaired, depriving organs of nutrients and oxygen. In severe cases, one or more organs fail. In the worst cases, blood pressure drops, the heart weakens, and the patient spirals toward septic shock. Once this happens, multiple organs—lungs, kidneys, liver—may quickly fail, and the patient can die.
Because sepsis is traditionally hard to diagnose, doctors do not always rec...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 26, 2017 Category: Research Authors: Chris Palmer Tags: Physical Trauma and Sepsis Source Type: blogs
Stories to help parents think critically about the importance of vaccinations
I was rotating through an infectious disease elective at an outside hospital during my fourth year of medical school when I encountered a startling situation. We were called to evaluate a patient who was suffering from an infection called Haemophilus influenzae. Now, I knew that most children were vaccinated against this pathogen, so I was surprised by the consult.
I was working on a team with three others: one attending, one fellow, and another medical student. We donned our gowns and our gloves, and we entered the intensive care unit. The sight before me is one that I will never forget. The child was connected to various...
Source: Kevin, M.D. - Medical Weblog - September 2, 2017 Category: General Medicine Authors: < a href="http://www.kevinmd.com/blog/post-author/cherilyn-cecchini" rel="tag" > Cherilyn Cecchini, MD < /a > Tags: Conditions Hospital-Based Medicine Infectious Disease Pediatrics Source Type: blogs
Early adjunctive gentamicin in severe sepsis and septic shock
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - August 2, 2017 Category: Internal Medicine Tags: critical care infectious disease Source Type: blogs
Research and Reviews in the Fastlane 189
This study compares emergency medical care statistics for an urban metropolitan community in Oregon before and after the implementation of the Affordable Care Act in the USA. With the incidence of cardiac arrest approximately 17 percent lower post ACA than before it certainly brings home the potential implications of repealing and replacing the ACA.
Recommended by: Virginia Newcombe
Emergency Medicine
van der Hulle T, et al; YEARS study group. Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study. Lancet 2017. PMID: 28549662
The largest demonstratio...
Source: Life in the Fast Lane - July 12, 2017 Category: Emergency Medicine Authors: Jeremy Fried Tags: Emergency Medicine R&R in the FASTLANE Resuscitation EBM Education recommendations research and reviews Source Type: blogs
The vitamin C cocktail for severe sepsis and septic shock
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - June 15, 2017 Category: Internal Medicine Tags: critical care infectious disease Source Type: blogs
LITFL Review 285
LITFL • Life in the Fast Lane Medical Blog
LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Welcome to the 285th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM.
The Most Fair Dinkum Ripper Beauts of the Week
Haney Mallemat shares some cheat codes for central line placement on 5 Minute Sono with Jaco...
Source: Life in the Fast Lane - June 13, 2017 Category: Emergency Medicine Authors: Anand Swaminathan Tags: LITFL review LITFL R/V Source Type: blogs
Research and Reviews in the Fastlane 185
This article on remifentanyl tolerance and hyperalgesia is nerdy, focussed on perioperative anaesthesia, but good.
Recommended by: Matthew MacPartlin
Emergency Medicine
Verma AA et al, for the GEMINI Investigators. Pulmonary Embolism and Deep Venous Thrombosis in Patients Hospitalized With Syncope: A Multicenter Cross-sectional Study in Toronto, Ontario, Canada. JAMA Intern Med. PMID: 28492876
A quick update on PESIT. This retrospective chart review tried to replicate the PESIT inclusion criteria. They identified 1305 patients admitted with first time syncope. Ultimately, 11 were diagnosed with PE and 10 with DVT, re...
Source: Life in the Fast Lane - June 7, 2017 Category: Emergency Medicine Authors: Justin Morgenstern Tags: Anaesthetics Emergency Medicine Intensive Care R&R in the FASTLANE critical care EBM Education literature recommendations research and reviews Source Type: blogs
Research and Reviews in the Fastlane 185
This article on remifentanyl tolerance and hyperalgesia is nerdy, focussed on perioperative anaesthesia, but good.
Recommended by: Matthew MacPartlin
Emergency Medicine
Verma AA et al, for the GEMINI Investigators. Pulmonary Embolism and Deep Venous Thrombosis in Patients Hospitalized With Syncope: A Multicenter Cross-sectional Study in Toronto, Ontario, Canada. JAMA Intern Med. PMID: 28492876
A quick update on PESIT. This retrospective chart review tried to replicate the PESIT inclusion criteria. They identified 1305 patients admitted with first time syncope. Ultimately, 11 were diagnosed with PE and 10 with DVT, re...
Source: Life in the Fast Lane - June 7, 2017 Category: Emergency Medicine Authors: Justin Morgenstern Tags: Anaesthetics Emergency Medicine Intensive Care R&R in the FASTLANE critical care EBM Education literature recommendations research and reviews Source Type: blogs
LITFL Review 284
LITFL • Life in the Fast Lane Medical Blog
LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Welcome to the 284th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM.
The Most Fair Dinkum Ripper Beauts of the Week
The EM Nerd eloquently reminds us that simplifying quality care to a simple time metric does...
Source: Life in the Fast Lane - June 4, 2017 Category: Emergency Medicine Authors: Anand Swaminathan Tags: LITFL review Source Type: blogs
Severe sepsis and septic shock: clinical audit 2016/17
Royal College of Emergency Medicine (RCEM) - This audit report finds that there has been an improvement in the proportion of patients receiving the best care for severe sepsis and septic shock, but that improvements are needed to make treatment available faster. ReportPress release (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - June 1, 2017 Category: UK Health Authors: The King ' s Fund Information & Knowledge Service Tags: Patient safety Quality of care and clinical outcomes Source Type: blogs
Research and Reviews in the Fastlane 179
This study is limited by its retrospective methods and by data originating from a single center with a bedside medical toxicology service.
Recommended by: Meghan Spyres
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The list of contributors
The R&R ARCHIVE
R&R Hall of famer You simply MUST READ this!
R&R Hot stuff! Everyone’s going to be talking about this
R&R Landmark paper A paper that made a difference
R&R Game Changer? Might change your clinical practice
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R&R Mona Lisa Brilliant writing or explanation
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Source: Life in the Fast Lane - April 20, 2017 Category: Emergency Medicine Authors: Nudrat Rashid Tags: Emergency Medicine Intensive Care Pediatrics Pre-hospital / Retrieval R&R in the FASTLANE Resuscitation Toxicology and Toxinology critical care Education literature recommendations research and reviews Source Type: blogs
LITFL Review 276
LITFL: Life in the Fast Lane Medical Blog
LITFL: Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Welcome to the 276th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM.
The Most Fair Dinkum Ripper Beauts of the Week
Vitamin C in Sepsis has been all over social media and the lay press as the “cure” for severe s...
Source: Life in the Fast Lane - April 2, 2017 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs
