Effect of Early Administration of Albumin 20% Versus Crystalloid
Conditions: Septic Shock Interventions: Drug: Albumin Human Sponsors: Egymedicalpedia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials
Health Related Quality of Life After Intensive Care for Sepsis, a National Cohort Study.
Conditions: Sepsis; Septic Shock; Sepsis, Severe Sponsors: Uppsala University Hospital; Sepsisfonden Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials
UK ANDROMEDA-Shock-2 RCT
Conditions: Septic Shock Interventions: Procedure: Personalised fluid and haemodynamic resuscitation Sponsors: Guy ' s and St Thomas ' NHS Foundation Trust; Pontificia Universidad Catolica de Chile; University of Rotterdam, The Netherlands Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials
Disseminated Intravascular Coagulation (DIC) Score and Organ Dysfunction in Septic Shock Patients
Conditions: Septic Shock; Disseminated Intravascular Coagulation Sponsors: Sanjay Gandhi Postgraduate Institute of Medical Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials
Effect of Statin Therapy on Sepsis-related Mortality in Intensive Care Unit Patients
Conditions: Sepsis; Septic Shock Interventions: Other: Person-level linkage of the database looking for relationship with sepsis survival and previous intake of certain drug families and previous dependence on health services. Sponsors: Hospital de Granollers; Department of Health, Generalitat de Catalunya Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
Evaluation of the Efficiency of Intermittent Enteral Nutrition on Multi-organ Failure From Patients With Mechanical Ventilation in Intensive Care Unit
Conditions: Intermittent Fasting; Septic Shock; Organ Failure, Multiple Interventions: Other: Intermittent enteral nutrition Sponsors: University Hospital, Rouen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials
A Study of Midodrine in Septic Shock
Conditions: Sepsis; Low Blood Pressure Interventions: Drug: Midodrine; Drug: Placebo Sponsors: Mayo Clinic Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2024 Category: Research Source Type: clinical trials
Intravenous Methylene Blue for Treating Refractory Neonatal Septic Shock
Conditions: Neonatal Sepsis; Shock, Septic Interventions: Drug: Methylene Blue; Other: Placebo Sponsors: Post Graduate Institute of Medical Education and Research, Chandigarh Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 12, 2024 Category: Research Source Type: clinical trials
The scientific rationale and study protocol for the DPP3, Angiotensin II, and Renin Kinetics in Sepsis (DARK-Sepsis) randomized controlled trial: serum biomarkers to predict response to angiotensin II versus standard-of-care vasopressor therapy in the treatment of septic shock
DiscussionWith an armamentarium of mechanistically distinct vasopressor agents now available, sub-phenotyping patients using biomarkers has the potential to improve septic shock outcomes by enabling treatment of the correct patient with the correct vasopressor at the correct time. However, this approach requires validation in a large definitive multicenter trial. The data generated through the DARK-Sepsis study will prove crucial to the optimal design and patient enrichment of such a pivotal trial.Trial registrationClinicalTrials.gov NCT05824767. Registered on April 24, 2023. (Source: Trials)
Source: Trials - March 12, 2024 Category: Research Source Type: clinical trials
Dexmedetomidine and Vasopressin in Septic Shock
Conditions: Sepsis; Septic Shock Interventions: Drug: DEX-PRESSIN; Drug: Standard of Care Sponsors: Mansoura University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
COronary Microcirculation and Troponin Elevation in Septic Shock
Conditions: Sepsis; Myocardial Injury; Coronary Microvascular Dysfunction; Endothelial Dysfunction Sponsors: Karolinska Institutet Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials
Molecular Endotype-Specific Dynamics of Lung Endothelial Barrier Integrity in Sepsis
Conditions: Sepsis; Septic Shock; Pneumonia Interventions: Diagnostic Test: Blood transcriptomics and BAL protein profiling Sponsors: Mater Dei Hospital, Malta; European Society of Intensive Care Medicine; University of Malta Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials
First in Human Trial to Assess the Safety & Efficacy of HemoSystem REBOOT in Patients With Sepsis-induced Immunosuppression
Conditions: Septic Shock Interventions: Device: REBOOT Hemosystem Sponsors: hemotune AG Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials
Euthyroid Sick Syndrome in Septic Shock
Conditions: Septic Shock Interventions: Other: observation Sponsors: Cantonal Hospital Zenica Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 5, 2024 Category: Research Source Type: clinical trials
The Effect of Vasopressor Therapy on Renal Perfusion in Septic Shock
Conditions: Septic Shock; Acute Kidney Injury Interventions: Drug: Angiotensin II; Drug: Vasopressin; Drug: Norepinephrine Sponsors: King ' s College Hospital NHS Trust; European Society of Intensive Care Medicine; Royal Centre for Defence Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 31, 2024 Category: Research Source Type: clinical trials
