Funding Opportunity: R21/R33 to Test Existing or New Biospecimens from Sepsis Patients
We’ve issued a new funding opportunity announcement (FOA): Exploring the Scientific Value of Existing or New Sepsis Human Biospecimen Collections (R21/R33 – Clinical Trial Not Allowed) (PAR-21-077). This FOA aims to promote the optimal use, testing, and sharing of patient-derived materials. It stems from recommendations of the NAGMSC working group on sepsis and input from the scientific community for strategies to rebalance NIGMS’ investment in sepsis research. This two-phase FOA supports a 2-year R21 award for up to $275,000 direct costs in the first phase, and a 2-year R33 award with a budget cap of $500...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - November 17, 2020 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Funding Opportunities Sepsis Research Source Type: blogs

Rapid Identification of Antibiotic-Resistant Infections: Interview with Jong Lee, CEO at Day Zero Diagnostics
Antibiotic resistance is a growing concern, with some predictions suggesting that routine surgery could be unacceptably risky in a future where many antibiotics have become obsolete. Part of the problem lies in the time it takes clinicians to diagnose an antibiotic-resistant infection. Current techniques involve lab technicians culturing a bacterial sample until it can be analyzed for drug resistance. The whole process takes days, and by the time the test provides an answer, a patient could be dead from sepsis. To address this, clinicians typically administer broad-spectrum antibiotics in an effort to bring an infection...
Source: Medgadget - November 11, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Medicine Pathology Public Health Source Type: blogs

Wanted: Program Director, Pharmacological and Physiological Sciences Branch
We’re recruiting for an accomplished scientist with interest and experience in sepsis, critical illness, and/or polytraumatic injury join the Pharmacological and Physiological Sciences (PPS) Branch of the Division of Pharmacology, Physiology, and Biological Chemistry (PPBC). The successful applicant will be responsible for scientific and administrative management of a portfolio of research, career development, and training grants. Opportunities also exist for Small Business Innovation and Small Business Technology Transfer (SBIR/STTR) grants. The PPS Branch of PPBC supports both basic and clinical research. This ...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - October 19, 2020 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Job Announcements Source Type: blogs

A gastroenterologist ’s COVID musings from behind the mask
I was recently asked to see an 89-year-old woman who was gravely ill in the intensive care unit. She was admitted with cholangitis due to bile duct stones causing complete obstruction leading to septic shock. It is a life-threatening situation, especially in elderly patients. She needed an emergency endoscopic procedure: ERCP. By the way, one […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 14, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/sripathi%e2%80%8b-kethu" rel="tag" > Sripathi ​ Kethu, MD < /a > < /span > Tags: Conditions COVID-19 coronavirus Gastroenterology Infectious Disease Source Type: blogs

Wanted: Program Director, Pharmacological and Physiological Sciences Branch
We’re recruiting for an accomplished scientist with interest and experience in total body responses to traumatic and other injuries, as well as sepsis, to join the Pharmacological and Physiological Sciences (PPS) Branch of the Division of Pharmacology, Physiology, and Biological Chemistry (PPBC). The successful applicant will have responsibility for scientific and administrative management of a portfolio of research, career development, and training grants. Opportunities also exist for Small Business Innovation and Small Business Technology Transfer (SBIR/STTR) grants. The PPS Branch of PPBC supports both basic an...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - September 11, 2020 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Job Announcements Source Type: blogs

Blood Volume Analysis Using The BVA-100: Interview with Michael Feldschuh, Daxor CEO
This study highlights the value of our technology and its potential to improve heart failure outcomes. There have been dozens of peer-reviewed studies that have established the value of the BVA-100 test for clinical use, confirming that accurate blood volume measurement leads to better informed physicians, better treatment strategies, and improves patient outcomes and resource utilization. Medgadget: What are the problems with surrogate measures of blood volume that clinicians sometimes use in the absence of a device such as the BVA-100? Michael Feldschuh: Physicians predominantly rely on clinical assessment...
Source: Medgadget - June 8, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Anesthesiology Cardiac Surgery Cardiology Critical Care Emergency Medicine Exclusive Source Type: blogs

Please don ’t call me a hero. This is what nurses have always done.
Before becoming a certified registered nurse anesthetist (CRNA), I was a surgical intensive care unit (SICU) nurse for decades. During that time, I often saw patients during their greatest time of need – trauma victims, transplant recipients, patients with brain tumors, ruptured aortas, and septic shock. I thought I had seen it all, but working […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - May 4, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/anonymous" rel="tag" > Anonymous < /a > < /span > Tags: Conditions COVID-19 coronavirus Critical Care Infectious Disease Source Type: blogs

Letting go when people let go of their lives
My 83-year-old patient had outlived peoples’ expectations on several occasions. Faced with a critical illness three years ago, she underwent emergency surgery and spent several months in the hospital with a series of complications, including septic shock, renal failure, and hospital-acquired pneumonia. I’d seen her in the office for a new visit soon after she […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - November 5, 2019 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/john-a-dodson" rel="tag" > John A. Dodson, MD < /a > < /span > Tags: Physician Cardiology Palliative Care Source Type: blogs

Effect of angiotensin II in patients with vasodilatory (mainly septic) shock requiring renal replacement therapy
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - March 12, 2019 Category: Internal Medicine Tags: critical care nephrology pharmacology Source Type: blogs

The 2011 norepi shortage was associated with increased mortality in septic shock
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - September 27, 2018 Category: Internal Medicine Tags: cardiovascular critical care pharmacology Source Type: blogs

Sepsis awareness: Should there be different awareness goals for the young and the old?
Sepsis, the body’s self-destructive inflammatory response to severe infection, is the leading cause of death in U.S. hospitals, particularly among the elderly. It starts as mild sepsis, advances to severe sepsis, and all too frequently blossoms into septic shock. More than 1.5 million Americans get sepsis each year. More than 250,000 die of the illness. One in three patients who die in a hospital have sepsis. 62percent of survivors are re-hospitalized within 30 days. Over 90 percent of cases start in the community. Understanding the critical role sepsis plays at the end of so many lives is important. September is Sepsis...
Source: Kevin, M.D. - Medical Weblog - September 4, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/samuel-harrington" rel="tag" > Samuel Harrington, MD < /a > Tags: Conditions Critical Care Hospital-Based Medicine Infectious Disease Source Type: blogs

LITFL Review 344
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Welcome to the 344th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM. The Most Fair Dinkum Ripper Beauts of the Week Catch up with the Curbsiders and hear Renee Dversdal talk about her passion for IMPOCUS...
Source: Life in the Fast Lane - August 20, 2018 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: LITFL review LITFL R/V Source Type: blogs

The Doctor Who Thwarted the Charge of the General Medical Council – Part 1
By  SAURABH JHA After Dr. Hadiza Bawa-Garba was convicted for manslaughter for delayed diagnosis of fatal sepsis in Jack Adcock, a six-year-old boy who presented to Leicester Royal Infirmary with diarrhea and vomiting, she was referred to the Medical Practitioners Tribunal (MPT). The General Medical Council (GMC) is the professional regulatory body for physicians. But the MPT determines whether a physician is fit to practice. Though the tribunal is nested within the GMC and therefore within an earshot of its opinions, it is a decision-making body which is theoretically independent of the GMC. The tribunal met in 2017, 6 ...
Source: The Health Care Blog - August 5, 2018 Category: Consumer Health News Authors: at RogueRad Tags: NHS #BawaGarba @roguerad Source Type: blogs

LITFL Review 341
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Welcome to the 341st LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM. Readers can subscribe to LITFL review RSS or LITFL review EMAIL subscription The Most Fair Dinkum Ripper Beauts of the Week PARAMEDIC-2 epi...
Source: Life in the Fast Lane - July 22, 2018 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: LITFL review LITFL R/V Source Type: blogs