The FDA Approves a New HPV Vaccine Containing Over Twice as Much Aluminum As its Predecessor
According to recent reports, the FDA has approved yet another HPV vaccine, despite documented safety issues and the new vaccine containing an exceptionally high level of aluminum, a known neurotoxin. Until now, only two vaccines have been manufactured to protect men and women against human papillomavirus (HPV), a virus believed to be the leading cause of cervical cancer: Cervarix, which is believed to protect against strains 16 and 18 of the virus, and Gardasil, which is believed to protect against strains 6, 11, 16 and 18.   //   A Third HPV Vaccine Hits the Market In December 2014, Gardasil 9 vaccine, manu...
Source: vactruth.com - February 1, 2015 Category: Allergy & Immunology Authors: Christina England Tags: Christina England Physical Top Stories aluminum hydroxide Food and Drug Administration (FDA) Gardasil 9 HPV Vaccine Merck Sharp and Dohme Source Type: blogs

Speeding Sepsis Response by Integrating Key Technology
Stephen Claypool, M.D., is Vice President of Clinical Development & Informatics, Clinical Solutions, with Wolters Kluwer Health and Medical Director of its Innovation Lab. He can be reached at steve.claypool@wolterskluwer.com. Three-week-old Jose Carlos Romero-Herrera was rushed to the ER, lethargic and unresponsive with a fever of 102.3. His mother watched helplessly as doctors, nurses, respiratory therapists and assorted other clinicians frantically worked to determine what was wrong with an infant who just 24 hours earlier had been healthy and happy. Hours later, Jose was transferred to the PICU where his heart ra...
Source: EMR and HIPAA - January 26, 2015 Category: Technology Consultants Authors: Guest Blogger Tags: Clinical Decision Support EHR Electronic Health Record Electronic Medical Record EMR Healthcare Interoperability HealthCare IT CDS Faces of Sepsis John Muir MEDITECH POC Advisor Sepsis Alerts Sepsis Alliance Sepsis Protocols Source Type: blogs

New Ideas for Old News: What Impact Can Mobile Gaming Have on the Sepsis Epidemic?
By: Kambria H. Evans, MEd, program officer, Quality and Organizational Improvement, Department of Medicine, Stanford University School of Medicine As a baby in the 1980s, I got very ill. When my condition worsened instead of improved, my mother found herself desperately pleading with ER nurses that I be admitted. My family would soon learn I was severely septic. Relatives came to the hospital to say good-bye. I lost almost a third of my body weight, my skin tone turned grey, and parts of my head were shaven to allow tubes to disappear into my small skull. While I don’t consciously remember this, it shaped my identity eac...
Source: Academic Medicine Blog - December 22, 2014 Category: Universities & Medical Training Authors: Guest Author Tags: Featured Guest Perspective gaming sepsis Stanford technology in medicine Source Type: blogs

CCC Update 009
Here is a quick overview of the major updates and revisions to the LITFL Critical Care Compendium since CCC Update 008.Check these out:Airway and cervical spine injuriesPeople can get pretty twitchy about intubating patients with suspected cervical spine injuries. Apply MILS, use a bougie and perform rapid sequence intubation. What’s so hard about that?… Airway management in Major TraumaAn overview of the issues affecting airway management in major trauma, including the indications for intubation the possible causes of airway compromise in this setting.Antimicrobial stewardshipUpdated with a recent systematic rev...
Source: Life in the Fast Lane - December 15, 2014 Category: Emergency Medicine Authors: Chris Nickson Tags: Critical Care Compendium Emergency Medicine FCICM Fellowship Intensive Care CCC update FCICM exam Source Type: blogs

Research and Reviews in the Fastlane 051
Welcome to the 51st edition of Research and Reviews in the Fastlane. R&R in the Fastlane is a free resource that harnesses the power of social media to allow some of the best and brightest emergency medicine and critical care clinicians from all over the world tell us what they think is worth reading from the published literature. This edition contains 10 recommended reads. The R&R Editorial Team includes Jeremy Fried, Nudrat Rashid, Soren Rudolph, Anand Swaminathan and, of course, Chris Nickson. Find more R&R in the Fastlane reviews in the R&R Archive, read more about the R&R project or check out...
Source: Life in the Fast Lane - October 6, 2014 Category: Emergency Medicine Authors: Nudrat Rashid Tags: Anaesthetics Cardiology Education Emergency Medicine Gastroenterology Infectious Disease Intensive Care Pre-hospital / Retrieval Respiratory Resuscitation critical care literature R&R in the FASTLANE recommendations Research an Source Type: blogs

Research and Reviews in the Fastlane 048
This study looked at one institution’s discrepancy rate between EP and radiologist plain film reads over 10 years. They found overall an ~3% discrepancy rate on all plain films. This of course does not mean the radiologist was correct in every discrepancy. But it does show we agree most of the time. Most interestingly, the rate of discrepancies requiring emergent change in management was a mere 0.056%! Recommended by: Zack Repanshek Prehospital/Retrieval Braude D et al. Air Transport of Patients with Pneumothorax: Is Tube Thoracostomy Required Before Flight? Air Med J. 2014 Jul-Aug;33(4):152-6. PMID: 25049185 C...
Source: Life in the Fast Lane - September 15, 2014 Category: Emergency Medicine Authors: Anand Swaminathan Tags: Anaesthetics Cardiology Education Emergency Medicine Pediatrics Pre-hospital / Retrieval Public Health Respiratory Resuscitation Toxicology and Toxinology critical care Intensive Care literature R&R in the FASTLANE recommendati Source Type: blogs

Research and Reviews in the Fastlane 047
In this study, the research team collected pooled urine (read many people used the urinal they collected from) from a popular nightclub area in London and analyzed the specimens for the presence of illicit drug compounds. The goal was to determine whether this method could be used to track patterns and monitor trends in recreational drug use.  Recommended by: Anand Swaminathan Emergency Medicine, Critical Care, Anaesthetics Hindman BJ et al. Intubation Biomechanics: Laryngoscope Force and Cervical Spine Motion during Intubation with Macintosh and Airtraq Laryngoscopes. Anesthesiology. 2014; 121(2):260-71. PMID...
Source: Life in the Fast Lane - September 9, 2014 Category: Emergency Medicine Authors: Anand Swaminathan Tags: Clinical Research Education Emergency Medicine R&R in the FASTLANE critical care Intensive Care literature recommendations Research and Review Source Type: blogs

Contrasting American EDs with the World’s Largest Hospital
By Zubair Chao, MD   Dr. Thomas Cook and I escaped the dry heat of South Carolina to land in Chengdu, China, home of West China Hospital, in July 2012. He was set to teach an emergency ultrasound class, and I was on a global mission as part of my emergency medicine residency.   Some say it is the largest hospital in the world, boasting 5,000 beds, nearly 100 operating suites, and a large outpatient center, which, on any given day, has about 10,000 patients.     West China Hospital   The ED at West China Hospital recently moved to its new home in a larger, more modern facility. It sees about 160,000 patients a...
Source: Going Global - September 3, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Contrasting American EDs with the World’s Largest Hospital
By Zubair Chao, MD   Dr. Thomas Cook and I escaped the dry heat of South Carolina to land in Chengdu, China, home of West China Hospital, in July 2012. He was set to teach an emergency ultrasound class, and I was on a global mission as part of my emergency medicine residency.   Some say it is the largest hospital in the world, boasting 5,000 beds, nearly 100 operating suites, and a large outpatient center, which, on any given day, has about 10,000 patients.     West China Hospital   The ED at West China Hospital recently moved to its new home in a larger, more modern facility. It sees about 160,000 patients a year, wh...
Source: Going Global - September 3, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Nitric oxide synthase – NOS1, NOS2, NOS3
Nitric oxide synthase Three important varieties of nitric oxide synthase involved in the synthesis of nitric oxide can be seen in the human system. They are neuronal, inducible and endothelial varieties. nNOS: neuronal nitric oxide synthase (NOS1): Neuronal nitric oxide synthase is involved in the production of nitric oxide in both central and peripheral nervous system.  iNOS: inducible nitric oxide synthase (NOS2): Inducible nitric oxide synthase also generates nitric oxide from L-arginine. Nitric oxide has an important role in blood pressure regulation and is also thought to have roles in infectious and malignant pr...
Source: Cardiophile MD - July 30, 2014 Category: Cardiology Authors: Prof. Dr. Johnson Francis MD, DM, FACC, FRCP Edin, FRCP London Tags: General Cardiology endothelial nitric oxide synthase eNOS eNOS substrate L-arginine inducible nitric oxide synthase iNOS neuronal nitric oxide synthase nNOS NOS1 NOS2 NOS3 Source Type: blogs

Continuum of Care on WIHI
Madge Kaplan writes:The next WIHI broadcast — From Prehospital to In-Hospital: The Continuum for Time-Sensitive Care — will take place on Thursday, July 24, from 2 to 3 PM ET, and I hope you'll tune in.Our guests will include:Kedar Mate, MD, Vice President, Institute for Healthcare Improvement (IHI)David Williams, PhD, Improvement Advisor and Founder, TrueSimpleJonathan R. Studnek, PhD, NRP, Quality Improvement Manager, Mecklenburg EMS Agency (North Carolina)Kevin Rooney, MBChB, FRCA, FFICM, Consultant in Anaesthesia and Intensive Care Medicine; Professor of Care Improvement, University of the West of Sc...
Source: Running a hospital - July 24, 2014 Category: Health Managers Source Type: blogs

Healthcare Update Satellite — 07-14-2014
Practicing telemedicine may just get a whole lot easier. Federation of State Medical Boards creating an interstate “compact” that would reduce barriers by providing an “expedited license” to physicians who wish to practice medicine in multiple states. The physician has to establish a state of “principal license” and then may apply to the “Interstate Commission” to receive a license in another state after the “applicable fees” have been paid. The hundreds of dollars per year paid to each state to maintain licensure don’t appear to be one of the barriers that ...
Source: WhiteCoat's Call Room - July 15, 2014 Category: Emergency Medicine Authors: WhiteCoat Tags: Healthcare Update Source Type: blogs

Research and Reviews in the Fastlane 039
Welcome to the 39th edition of Research and Reviews in the Fastlane. R&R in the Fastlane is a free resource that harnesses the power of social media to allow some of the best and brightest emergency medicine and critical care clinicians from all over the world tell us what they think is worth reading from the published literature. This edition contains 13 recommended reads. The R&R Editorial Team includes Jeremy Fried, Nudrat Rashid, Soren Rudolph, Anand Swaminathan and, of course, Chris Nickson. Find more R&R in the Fastlane reviews in the R&R Archive, read more about the R&R project or check out the f...
Source: Life in the Fast Lane - July 14, 2014 Category: Emergency Medicine Authors: Soren Rudolph Tags: Anaesthetics Cardiology Emergency Medicine Emergency Medicine Update Featured Infectious Disease Intensive Care Pre-hospital / Retrieval Resuscitation critical care literature R&R in the FASTLANE recommendations research and revi Source Type: blogs

The Price of Compassion - Commercialized Hospices and the Mistreatment of Vulnerable Patients
Introduction - Commercialized Hospices We have occasionally written about the rise of the commercialized hospice industry, and concerns that commercialized hospices may not be providing the compassionate care they promise.  As we have discussed before, the hospice movement began with small, non-profit, community based organizations meant to provide compassionate palliative care to the terminally ill.  However, in the US, the hospice movement has been co-opted by commercial hospices, often run by large corporations, which may put profit ahead of compassion.Several long investigative articles have appeared this yea...
Source: Health Care Renewal - July 10, 2014 Category: Health Management Tags: Carlyle Group deception Fillmore Partners Gentiva Golden Living HCR ManorCare hospices marketing private equity Vitas Source Type: blogs

The importance of recognizing immunodeficiency
On a cold, blustery Cleveland day when I was a resident, a forty-year-old man walked into our infectious disease clinic at the Cleveland Clinic. The patient was undergoing routine visits in preparation for a kidney transplant. This poor man had been hospitalized six months earlier at another hospital where he caught a terrible infection and was readmitted in septic shock and multi-organ failure. Luckily he survived, but in the process lost some of his toes as well as his kidney function. Thus, he was now on dialysis and awaiting a new kidney. The organism to blame was streptococcus pneumoniae, which causes pneumonias and e...
Source: Kevin, M.D. - Medical Weblog - July 3, 2014 Category: Journals (General) Authors: Tags: Conditions Specialist Source Type: blogs