Sclerosing stromal tumor of the ovary in a postmenopausal woman with estrogen excess: A case report
We describe the first case of ovarian SST with estrogen excess with both clinical and serological evidence in a postmenopausal woman.
Patient concerns:
A 70-year-old female who referred menopause 14 years ago was admitted with postmenopausal bleeding for 3 months. Ultrasonography revealed thickened endometrium of 6 mm and no adnexal masses. An elevated serum estradiol level of 49.78 ng/L was revealed in laboratory examination with normal ranges less than 27.25 ng/L in postmenopausal women.
Diagnoses:
The final histology diagnosis is SST of left ovary and endometrial hyperplasia with polyps.
Interventions:
Laparo...
Source: Medicine - November 1, 2019 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
An Epithelioid Smooth Muscle Neoplasm Mimicking a Signet Ring Cell Carcinoma in the Ovary
A 53-yr-old woman who presented with elevated renal indices was discovered to have a 4.5 cm right renal mass and an incidental 9.7 cm left ovarian mass on imaging studies. She underwent a partial nephrectomy and bilateral salpingo-oophorectomy, revealing a chromophobe renal cell carcinoma and an unusual ovarian neoplasm with epithelioid cells displaying prominent signet ring cell-like morphology. Immunohistochemical analysis of the ovarian neoplasm demonstrated that the tumor cells were diffusely immunoreactive for smooth muscle markers and negative for all tested cytokeratins and epithelial membrane antigen. On the ba...
Source: International Journal of Gynecological Pathology - August 7, 2019 Category: Pathology Tags: Pathology of the Upper Genital Tract: Case Reports Source Type: research
Ovarian Sex Cord-Stromal Tumors: Reflections on a 40-Year Experience With a Fascinating Group of Tumors, Including Comments on the Seminal Observations of Robert E. Scully, MD.
CONCLUSIONS.—: The essay begins with remarks on the oftentimes straightforward stromal tumors of the ovary because the commonest of them, the fibroma, dominates from the viewpoint of case numbers. Then, the sclerosing stromal tumor and the peculiar so-called luteinized thecomas of the type associated with sclerosing peritonitis are discussed in greater detail and their wide spectrum is illustrated. Brief mention is made of 2 rare neoplasms: the ovarian myxoma and signet-ring stromal tumor. Discussion then turns to the more recently recognized intriguing tumor tentatively designated microcystic stromal tumor and the commo...
Source: Archives of Pathology and Laboratory Medicine - December 1, 2018 Category: Laboratory Medicine Authors: Young RH Tags: Arch Pathol Lab Med Source Type: research
EP19.10: HDliveFlow silhouette mode with HDlive silhouette mode for diagnosis of sclerosing stromal tumour of the ovary
Ultrasound in Obstetrics&Gynecology,Volume 52, Issue S1, Page 271-271, October 2018. (Source: Ultrasound in Obstetrics and Gynecology)
Source: Ultrasound in Obstetrics and Gynecology - October 16, 2018 Category: Radiology Authors: C. Tenkumo,
U. Hanaoka,
K. Kanenishi,
T. Hata Source Type: research
Sclerosing stromal cell tumor of ovary
Publication date: Available online 2 December 2017Source: Medical Journal Armed Forces IndiaAuthor(s): Shazia Khan, Virendra Singh, I.D. Khan, Sujatha Panda (Source: Medical Journal Armed Forces India)
Source: Medical Journal Armed Forces India - July 10, 2018 Category: General Medicine Source Type: research
Sclerosing stromal tumor of the ovary in a perimenopausal woman: a case report.
Authors: Liu SJ, Lv W, Shi M
Abstract
Sclerosing stromal tumor (SST) is a rare ovarian neoplasia deriving from the sex cord stromal tumor, which occurs usually in the sec- ond and third decades of life. However, the authors report a 46-year old multiparous woman who presented with a cystic-solid left pelvic mass, a large amount of ascites, and elevated serum CA-125, all suggesting a malignant tumor. Surgery was performed and final histopathological diagnosis of the specimen was diagnosed with SST. The authors herein report an extremely rare case of SST with a cystic-solid pelvic mass and a large amount of ...
Source: European Journal of Gynaecological Oncology - July 1, 2018 Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research
Different Presentations of Five Rare Cases of Sclerosing Stromal Tumor of the Ovary
AbstractA rare subtype of preceding neoplasm of ovary is sclerosing stromal cell tumor with few presented cases in the literature. In these case series, we describe five cases of ovarian sclerosing stromal cell tumor with different presentations in our department. Interestingly, one of our cases had elevated alfa-fetoprotein. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - May 19, 2018 Category: Cancer & Oncology Source Type: research
Expression of angiogenic factors in sclerosing stromal tumours of the ovary.
Authors: Hirakawa T, Kawano Y, Mizoguchi C, Nasu K, Narahara H
Abstract
Sclerosing stromal tumours (SSTs) are rare benign tumours and are generally observed in individuals in their teens to 20 s. Many cases are suspected as malignant tumours pre-operatively, owing to their high vascularity on diagnostic imaging. Herein, we aimed to evaluate the expressions of various angiogenic factors in SSTs. The expressions of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) and hepatocyte growth factor (HGF) were examined by immunohistochemical staining. Upon immunohistochemistry, over...
Source: Journal of Obstetrics and Gynaecology - February 14, 2018 Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
Solitary fibrous tumour of the female genital tract: a clinicopathological analysis of 25 cases
ConclusionGynaecological SFT can be diagnosed reliably with careful morphological evaluation and judicious use of immunohistochemical stains, and should be considered in the diagnostic workup of spindle cell tumours of unclear lineage in the female genital tract. (Source: Histopathology)
Source: Histopathology - January 26, 2018 Category: Pathology Authors: Eric J Yang, Brooke E Howitt, Christopher D M Fletcher, Marisa R Nucci Tags: Original Article Source Type: research
Sclerosing stromal cell tumor of ovary
Publication date: Available online 2 December 2017 Source:Medical Journal Armed Forces India Author(s): Shazia Khan, Virendra Singh, I.D. Khan, Sujatha Panda (Source: Medical Journal Armed Forces India)
Source: Medical Journal Armed Forces India - December 2, 2017 Category: General Medicine Source Type: research
Solitary Fibrous Tumor of the Female Genital Tract: A Clinicopathologic Analysis of 25 Cases
ConclusionGynecologic SFT can be diagnosed reliably with careful morphologic evaluation and judicious use of immunohistochemical stains, and should be considered in the diagnostic workup of spindle cell tumors of unclear lineage in the female genital tract.This article is protected by copyright. All rights reserved. (Source: Histopathology)
Source: Histopathology - November 1, 2017 Category: Pathology Authors: Eric J Yang, Brooke E Howitt, Christopher DM Fletcher, Marisa R. Nucci Tags: Original Article Source Type: research
Variable Distribution of Pseudolobules in Ovarian Sclerosing Stromal Tumors: Utility of Diffusion-weighted Imaging for Differential Diagnosis.
PMID: 28515408 [PubMed - as supplied by publisher] (Source: Magnetic Resonance in Medical Sciences : MRMS)
Source: Magnetic Resonance in Medical Sciences : MRMS - May 18, 2017 Category: Radiology Authors: Ito K, Tanaka YO, Watanabe R, Tanaka H, Takazawa Y, Matsueda K Tags: Magn Reson Med Sci Source Type: research
Benign Tumors Masquerading as Malignant: A Case of Sclerosing Stromal Tumor of the Ovary in an Adolescent
We describe clinical findings and histological features of an adolescent who presented with irregular menses and lower back pain. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2017 Category: OBGYN Authors: Nana Ama Ofei-Tenkorang, Rula V. Kanj, Lesley L. Breech Source Type: research
