TFE3 is a Novel Biomarker of Ovarian Sclerosing Stromal Tumours
Res Sq. 2023 Feb 13:rs.3.rs-2563971. doi: 10.21203/rs.3.rs-2563971/v1. Preprint.ABSTRACTSclerosing stromal tumours of the ovary are benign and tend to occur in young women with lobular structures at low frequencies. Three types of cells, luteinized cells, short spindle myoid cells, and intermediate cells, are found in lobules, which are rich in blood vessels. Currently, immunohistochemistry and fluorescence in situ hybridization are used to detect normal follicles, sclerosing stromal tumours, granulosa cell tumours, and theca fibromas. Our research found the expression of transcription factor enhancer 3 (TFE3) was moderate...
Source: Cell Research - February 24, 2023 Category: Cytology Authors: Li Zhao Yan Zhou Yuping Liu Qiuping Luo Qingping Jiang Hui Wang Na Wang Source Type: research

Ovarian collision tumor consisting of sclerosing stromal tumor and mature cystic teratoma complicated with Meigs syndrome: A case report
Oncol Lett. 2022 Oct 26;24(6):443. doi: 10.3892/ol.2022.13563. eCollection 2022 Dec.ABSTRACTOvarian collision tumors are uncommon and reports of their radiological appearance are even less frequent. The present study reported the world's first case of an ovarian collision tumor consisting of an ovarian sclerosing stromal tumor and a mature cystic teratoma and its imaging presentation. When a cystic solid ovarian mass combined with ascites and elevated CA125 is encountered it is frequently diagnosed as a malignant tumor, but the present case was a benign tumor. Therefore, when encountering similar cases, clinicians should n...
Source: Oncology Letters - November 24, 2022 Category: Cancer & Oncology Authors: Jiaren Zhang Lian He Li Yang Ji Wang Ling Wei Xuejing Ma Lin Jiang Source Type: research

Ovarian collision tumor consisting of sclerosing stromal tumor and mature cystic teratoma complicated with Meigs syndrome: A case report
Oncol Lett. 2022 Oct 26;24(6):443. doi: 10.3892/ol.2022.13563. eCollection 2022 Dec.NO ABSTRACTPMID:36420070 | PMC:PMC9647795 | DOI:10.3892/ol.2022.13563 (Source: Oncology Letters)
Source: Oncology Letters - November 24, 2022 Category: Cancer & Oncology Authors: Jiaren Zhang Lian He Li Yang Ji Wang Ling Wei Xuejing Ma Lin Jiang Source Type: research

Imaging characteristics of ovarian sclerosing stromal tumor
This study was designed to evaluate the specific imaging features of ovarian sclerosing stromal tumor (SST), improve its accuracy as well as the specificity of imaging diagnosing, and prevent overestimation of... (Source: BMC Women's Health)
Source: BMC Women's Health - September 1, 2022 Category: OBGYN Authors: Zhifeng Zhou, Xiaoqiao Chen, Zhibin Zeng, Fangjing Zhang, Jing Yan and Gangqiang Hou Tags: Research Source Type: research

Minimally Invasive Ovarian-Preserving Approach for the Management of a Sclerosing Stromal Tumor in an Adolescent: A Case Report
Sclerosing stromal tumors (SSTs) are rare benign ovarian tumors that occur in adolescents and young adults. They are often treated with unilateral salpingo-oopherectomy due to concern for malignancy. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - February 2, 2022 Category: OBGYN Authors: Chaarushi Ahuja, Joan Tymon-Rosario, Douglas Rottmann, Rita Abi Raad, Dan-Arin Silasi, Alla Vash-Margita Source Type: research

47. Minimally Invasive Ovarian-Preserving Approach for the Management of a Sclerosing Stromal Tumor in an Adolescent
Sclerosing stromal tumor (SST) is a rare benign ovarian tumor that primarily occurs in the 2nd and 3rd decades of life with the most common presentation being abdominal pain due to a pelvic mass. Due to its rarity, ambiguous laboratory results, and imaging findings concerning for malignancy, unilateral salpingo-oophorectomy is often performed. There are scant case reports describing a laparoscopic approach of tumor enucleation allowing ovarian preservation. Herein, we present a case of SST in an adolescent treated via a minimally invasive ovarian-sparing technique. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - March 23, 2021 Category: OBGYN Authors: Chaarushi Ahuja, Douglas Rottmann, Joan Tymon-Rosario, Rita Abi Raad, Dan Arin-Silasi, Alla Vash-Margita Source Type: research

Juvenile Granulosa Cell Tumors of the Ovary.
CONCLUSIONS: JGCT is a rare neoplasm with a wide morphologic spectrum and is easily confused with other tumors. Familiarity with the characteristics, rare atypical appearances, and immunohistochemical results may aid in obtaining a correct diagnosis. PMID: 32561911 [PubMed - as supplied by publisher] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - June 19, 2020 Category: Pathology Authors: Ye Y, Lv C, Xu S, Chen Y, Qian R, Wang P, Wang S Tags: Am J Clin Pathol Source Type: research

Ovarian Sclerosing Stromal Tumor and Müllerian Cyst in an 11-yr-old Girl: A Case Report and Review of the Literature
Sclerosing stromal tumor (SST) is an extremely rare ovarian neoplasm that primarily affects young female individuals. Patients with SST often present with pelvic pain and menstrual irregularities. Herein, we report a case of SST of the ovary in an 11-yr-old girl with symptoms of abdominal pain and menstrual irregularities. A preoperative diagnosis of tumors in the left adnexa and right ovary was made by pelvic ultrasonography and magnetic resonance imaging, and the patient underwent exploratory laparotomy and laparoscopic cystectomy. The ovarian masses were removed and proven to be SST in the left ovary and Müllerian cyst...
Source: International Journal of Gynecological Pathology - February 12, 2020 Category: Pathology Tags: Online Article: Case Report Source Type: research